Strain Name:
C57BL/6J-MtgxR0625Btlr/Mmmh
Stock Number:
038814-MU
Citation ID:
RRID:MMRRC_038814-MU
Other Names:
R0625 (G1), C57BL/6J-MtgxR0625Btlr
Major Collection:

Gene Information

Nes
Name: nestin
Synonyms: RC2, Marc2, ESTM46, Ifaprc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Foxm1
Name: forkhead box M1
Synonyms: Mpm2, WIN, HFH-11B, Trident, Fkh16, Foxm1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14235
HGNC: HGNC:3818
Homologene: 7318
Usp7
Name: ubiquitin specific peptidase 7
Synonyms: 2210010O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 252870
Homologene: 2592
Cxxc5
Name: CXXC finger 5
Synonyms: 4930415K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67393
VEGA: 18
Homologene: 9517
Qtrt1
Name: queuine tRNA-ribosyltransferase catalytic subunit 1
Synonyms: Tgt, tRNA-guanine transglycosylase, 2610028E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 60507
VEGA: 9
Homologene: 11061
Dock5
Name: dedicator of cytokinesis 5
Synonyms: lr2, 1110060D06Rik, rlc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68813
VEGA: 14
Homologene: 57016
Cnot6
Name: CCR4-NOT transcription complex, subunit 6
Synonyms: A230103N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104625
Homologene: 69187
Sec24a
Name: Sec24 related gene family, member A (S. cerevisiae)
Synonyms: 9430090N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77371
Homologene: 70131
Cdc37l1
Name: cell division cycle 37-like 1
Synonyms: 2700033A15Rik, Hsp90-associating relative of Cdc37, Harc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67072
VEGA: 19
Homologene: 9912
Parn
Name: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: DAN, 1200003I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74108
VEGA: 16
HGNC: HGNC:8609
Homologene: 31098
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: 2210008I11Rik, Zzank1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76580
Homologene: 16062
Podxl2
Name: podocalyxin-like 2
Synonyms: D130074J02Rik, PODLX2, Endoglycan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319655
Homologene: 9254
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Stau2
Name: staufen double-stranded RNA binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 29819
Homologene: 8666
Paxip1
Name: PAX interacting (with transcription-activation domain) protein 1
Synonyms: PTIP, D5Ertd149e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 55982
HGNC: HGNC:8624
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66686
Homologene: 12010
Ttc7b
Name: tetratricopeptide repeat domain 7B
Synonyms: Ttc7l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104718
VEGA: 12
Homologene: 14675
Marchf11
Name: membrane associated ring-CH-type finger 11
Synonyms: March11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211147
Homologene: 45584
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233810
Homologene: 132942
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: HKalpha2, cHKA, Atp1al1, ATPase H+K+-transporting, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192113
VEGA: 14
Homologene: 68197
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Fam160a1
Name: family with sequence similarity 160, member A1
Synonyms: 9930021J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229488
Homologene: 85149
Med12l
Name: mediator complex subunit 12-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329650
Homologene: 43143
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Olfr905
Name: olfactory receptor 905
Synonyms: GA_x6K02T2PVTD-32165709-32166641, MOR167-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258800
VEGA: 9
Homologene: 110524
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Skint2
Name: selection and upkeep of intraepithelial T cells 2
Synonyms: OTTMUSG00000008540, B7S3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329919
Homologene: 136741
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 666060
Homologene: 8939
Ppp3cc
Name: protein phosphatase 3, catalytic subunit, gamma isoform
Synonyms: PP2BA gamma, Calnc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19057
VEGA: 14
HGNC: HGNC:9316
Homologene: 68475
Olfr1104
Name: olfactory receptor 1104
Synonyms: GA_x6K02T2Q125-48508763-48507833, MOR207-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258763
Homologene: 64916
Itih2
Name: inter-alpha trypsin inhibitor, heavy chain 2
Synonyms: Intin2, Itih-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16425
HGNC: HGNC:6167
Homologene: 1668
Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
Synonyms: VPS10 domain receptor protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81840
Homologene: 56899
Smarca5
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Synonyms: Snf2h, D330027N15Rik, 4933427E24Rik, D030040M08Rik, MommeD4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 93762
Homologene: 55764
Shox2
Name: short stature homeobox 2
Synonyms: Prx3, Og12x, 6330543G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20429
Homologene: 68535
4930550C14Rik
Name: RIKEN cDNA 4930550C14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75311
VEGA: 9
Homologene: 12595
Erich5
Name: glutamate rich 5
Synonyms: BC030476
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239368
VEGA: 15
Homologene: 52129
Arhgap22
Name: Rho GTPase activating protein 22
Synonyms: RHOGAP2, B230341L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239027
Homologene: 23292
Cep44
Name: centrosomal protein 44
Synonyms: 4933440G23Rik, BC088983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382010
Homologene: 12738
Ttll3
Name: tubulin tyrosine ligase-like family, member 3
Synonyms: 4833441J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101100
Homologene: 134361
Gm5501
Name: predicted gene 5501
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433161
Arhgap11a
Name: Rho GTPase activating protein 11A
Synonyms: GAP (1-12), 6530401L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228482
Homologene: 8862
Phc2
Name: polyhomeotic 2
Synonyms: Mph2, D4Ertd810e, Edr2, D130050K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54383
HGNC: HGNC:3183
Homologene: 75090
Prl7d1
Name: prolactin family 7, subfamily d, member 1
Synonyms: PRP, PLF-RP, Plfr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18814
Homologene: 7894
C2cd4b
Name: C2 calcium-dependent domain containing 4B
Synonyms: 3300001A09Rik, Fam148b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75697
Homologene: 78036
Hacd4
Name: 3-hydroxyacyl-CoA dehydratase 4
Synonyms: 4933428I03Rik, Ptplad2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66775
Homologene: 12033
Pla2g4f
Name: phospholipase A2, group IVF
Synonyms: 4732472I07Rik, Pla2zeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271844
Homologene: 77933
Pramel7
Name: PRAME like 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 347712
Homologene: 87261
Gfra4
Name: glial cell line derived neurotrophic factor family receptor alpha 4
Synonyms: GFR alpha-4, G630015H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14588
Homologene: 10565
Acer2
Name: alkaline ceramidase 2
Synonyms: 2410116I05Rik, Asah3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230379
Homologene: 14986
Ctrc
Name: chymotrypsin C (caldecrin)
Synonyms: 1810044E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76701
HGNC: HGNC:2523
Homologene: 21422
Oas1a
Name: 2'-5' oligoadenylate synthetase 1A
Synonyms: L3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246730
HGNC: HGNC:8086
Homologene: 1903
N4bp2l1
Name: NEDD4 binding protein 2-like 1
Synonyms: B230342M21Rik, 2410024N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100637
Homologene: 14151
Olfr477
Name: olfactory receptor 477
Synonyms: GA_x6K02T2PBJ9-10319672-10320604, MOR204-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258928
Homologene: 27246
Plpbp
Name: pyridoxal phosphate binding protein
Synonyms: 2200002F22Rik, Prosc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 114863
HGNC: HGNC:9457
Homologene: 5211
Mlx
Name: MAX-like protein X
Synonyms: BigMax alpha, Tcfl4, bHLHd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21428
Homologene: 7969
Tmem114
Name: transmembrane protein 114
Synonyms: 4930511J11Rik, Cldn26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74720
VEGA: 16
Homologene: 12583
Cyp4f37
Name: cytochrome P450, family 4, subfamily f, polypeptide 37
Synonyms: Gm9705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 677156
VEGA: 17
Homologene: 135840
Marchf3
Name: membrane associated ring-CH-type finger 3
Synonyms: 6330411I15Rik, A530081L18Rik, March3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 320253
Homologene: 35310
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 16,369,743 bp
  • C to T, chromosome 2 at 10,123,414 bp
  • T to A, chromosome 2 at 87,021,620 bp
  • T to A, chromosome 2 at 87,491,008 bp
  • T to C, chromosome 2 at 113,841,711 bp
  • T to A, chromosome 2 at 120,305,041 bp
  • T to C, chromosome 2 at 120,713,990 bp
  • C to T, chromosome 2 at 131,040,256 bp
  • G to A, chromosome 3 at 59,247,437 bp
  • T to G, chromosome 3 at 66,981,544 bp
  • A to G, chromosome 3 at 85,730,500 bp
  • A to G, chromosome 3 at 87,977,172 bp
  • A to G, chromosome 4 at 45,284,055 bp
  • A to G, chromosome 4 at 86,887,162 bp
  • T to C, chromosome 4 at 88,435,010 bp
  • T to A, chromosome 4 at 112,624,086 bp
  • C to G, chromosome 4 at 128,723,710 bp
  • T to C, chromosome 4 at 141,841,518 bp
  • C to T, chromosome 4 at 155,659,460 bp
  • G to A, chromosome 5 at 27,765,942 bp
  • T to A, chromosome 5 at 36,024,572 bp
  • A to T, chromosome 5 at 110,325,550 bp
  • T to C, chromosome 5 at 120,899,259 bp
  • T to C, chromosome 5 at 129,171,931 bp
  • T to A, chromosome 5 at 150,576,745 bp
  • G to A, chromosome 6 at 84,111,987 bp
  • G to A, chromosome 6 at 88,849,955 bp
  • A to G, chromosome 6 at 113,408,903 bp
  • A to G, chromosome 6 at 128,373,871 bp
  • T to A, chromosome 6 at 146,166,651 bp
  • T to C, chromosome 7 at 107,991,189 bp
  • A to G, chromosome 7 at 120,071,887 bp
  • A to C, chromosome 7 at 120,435,893 bp
  • T to C, chromosome 7 at 141,846,427 bp
  • A to T, chromosome 8 at 27,045,131 bp
  • C to T, chromosome 8 at 56,545,395 bp
  • A to G, chromosome 8 at 80,720,686 bp
  • G to T, chromosome 9 at 21,418,288 bp
  • T to C, chromosome 9 at 38,473,208 bp
  • T to C, chromosome 9 at 53,408,065 bp
  • T to C, chromosome 9 at 54,382,702 bp
  • T to A, chromosome 9 at 67,759,751 bp
  • T to G, chromosome 10 at 52,312,850 bp
  • A to T, chromosome 11 at 49,683,171 bp
  • T to A, chromosome 11 at 51,729,454 bp
  • T to C, chromosome 11 at 101,087,782 bp
  • T to A, chromosome 12 at 100,355,046 bp
  • A to T, chromosome 13 at 27,710,140 bp
  • A to G, chromosome 14 at 33,366,714 bp
  • T to C, chromosome 14 at 56,372,837 bp
  • A to T, chromosome 14 at 67,841,163 bp
  • T to C, chromosome 14 at 70,225,027 bp
  • A to G, chromosome 15 at 26,311,043 bp
  • A to G, chromosome 15 at 34,471,369 bp
  • T to C, chromosome 16 at 8,412,102 bp
  • C to T, chromosome 16 at 8,704,982 bp
  • C to T, chromosome 16 at 13,640,294 bp
  • T to G, chromosome 17 at 32,634,678 bp
  • T to C, chromosome 18 at 9,917,195 bp
  • T to G, chromosome 18 at 35,858,589 bp
  • A to G, chromosome 18 at 56,811,830 bp
  • G to A, chromosome 19 at 29,007,705 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0625 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038814-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.