Strain Name:
C57BL/6J-MtgxR0714Btlr/Mmmh
Stock Number:
038897-MU
Citation ID:
RRID:MMRRC_038897-MU
Other Names:
R0714 (G1), C57BL/6J-MtgxR0714Btlr
Major Collection:

Gene Information

Arhgap10
Name: Rho GTPase activating protein 10
Synonyms: PSGAP-s, PSGAP-m, A930033B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78514
Homologene: 12695
Nedd4
Name: neural precursor cell expressed, developmentally down-regulated 4
Synonyms: Nedd4-1, Nedd4, Nedd4a, E430025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17999
HGNC: HGNC:7727
Homologene: 134533
Ccr2
Name: chemokine (C-C motif) receptor 2
Synonyms: CC-CKR-2, CKR2B, CKR2A, CCR2B, CCR2A, CKR2, Cmkbr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12772
HGNC: HGNC:1603
Homologene: 537
Sdhc
Name: succinate dehydrogenase complex, subunit C, integral membrane protein
Synonyms: 0610010E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66052
Homologene: 2256
Utp23
Name: UTP23 small subunit processome component
Synonyms: 1700010I21Rik, D530033C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78581
Homologene: 41789
Dhx35
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 35
Synonyms: Ddx35, 1200009D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71715
Homologene: 6406
Dmd
Name: dystrophin, muscular dystrophy
Synonyms: Duchenne muscular dystrophy, mdx, pke, X-linked muscular dystrophy, Dp427, Dp71, dys
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 13405
HGNC: HGNC:2928
Homologene: 20856
Abhd17b
Name: abhydrolase domain containing 17B
Synonyms: 5730446C15Rik, Fam108b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226016
VEGA: 19
Homologene: 41089
St13
Name: suppression of tumorigenicity 13
Synonyms: PRO0786, HSPABP1, SNC6, p48, Hsp70 interacting protein, 3110002K08Rik, 1110007I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70356
Homologene: 2921
Aspscr1
Name: alveolar soft part sarcoma chromosome region, candidate 1 (human)
Synonyms: ASPCR1, RCC17, ASPC, 1190006K01Rik, TUG, ASPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68938
Homologene: 41550
St7l
Name: suppression of tumorigenicity 7-like
Synonyms: St7r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229681
Homologene: 14910
Tonsl
Name: tonsoku-like, DNA repair protein
Synonyms: 2810439M11Rik, Nfkbil2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72749
HGNC: HGNC:7801
Homologene: 22754
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: 2210008I11Rik, Zzank1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76580
Homologene: 16062
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: 8430415E05Rik, 1700034M03Rik, Ccdc132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73288
Homologene: 11498
Emc7
Name: ER membrane protein complex subunit 7
Synonyms: 2900064A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73024
Homologene: 10597
Vps11
Name: VPS11, CORVET/HOPS core subunit
Synonyms: 1200011A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71732
VEGA: 9
Homologene: 6673
Nxph4
Name: neurexophilin 4
Synonyms: 1110036M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 104080
HGNC: HGNC:8078
Homologene: 11020
Sidt2
Name: SID1 transmembrane family, member 2
Synonyms: CGI-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214597
Homologene: 22943
Alb
Name: albumin
Synonyms: Alb-1, Alb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11657
HGNC: HGNC:399
Homologene: 405
Lnx1
Name: ligand of numb-protein X 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16924
HGNC: HGNC:6657
Homologene: 7819
Larp7
Name: La ribonucleoprotein 7, transcriptional regulator
Synonyms: D3Wsu161e, C330027G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 28036
Homologene: 88843
Fbxo34
Name: F-box protein 34
Synonyms: 5830426G16Rik, 2900057B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78938
VEGA: 14
Homologene: 12713
Dhx29
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 29
Synonyms: E130202M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218629
VEGA: 13
Homologene: 10387
Ttc13
Name: tetratricopeptide repeat domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234875
Homologene: 11569
Tmem130
Name: transmembrane protein 130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243339
Homologene: 17680
Kat2a
Name: K(lysine) acetyltransferase 2A
Synonyms: PCAF-B/GCN5, 1110051E14Rik, Gcn5, Gcn5l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14534
HGNC: HGNC:4201
Homologene: 41343
Adamts13
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Nudt8
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 8
Synonyms: 2310039H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66387
VEGA: 19
HGNC: HGNC:8055
Homologene: 41633
Exoc7
Name: exocyst complex component 7
Synonyms: sec70, 70kDa, Exo70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53413
Homologene: 41019
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212392
Homologene: 17668
Capn3
Name: calpain 3
Synonyms: Capa-3, Capa3, Lp82, p94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12335
HGNC: HGNC:1480
Homologene: 52
Sik2
Name: salt inducible kinase 2
Synonyms: G630080D20Rik, Snf1lk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235344
Homologene: 22875
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74362
Homologene: 52601
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233424
Homologene: 45588
Slc5a4b
Name: solute carrier family 5 (neutral amino acid transporters, system A), member 4b
Synonyms: 2010104G07Rik, pSGLT2, SAAT1, SGLT3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64454
Homologene: 56968
Pcdhb15
Name: protocadherin beta 15
Synonyms: Pcdhb7, PcdhbO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93886
HGNC: HGNC:8692
Homologene: 32429
Or9g4b
Name: olfactory receptor family 9 subfamily G member 4B
Synonyms: GA_x6K02T2Q125-47264151-47265089, MOR213-3, Olfr1015
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258564
Homologene: 115499
Nt5dc3
Name: 5'-nucleotidase domain containing 3
Synonyms: Gnn, C630002B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103466
VEGA: 10
Homologene: 9571
Nrsn2
Name: neurensin 2
Synonyms: LOC228777, Neurensin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228777
Homologene: 11802
Slx1b
Name: SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Synonyms: 4833422P03Rik, 2410170E21Rik, 1110030E23Rik, Giyd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75764
Homologene: 11434
Fndc3c1
Name: fibronectin type III domain containing 3C1
Synonyms: LOC333564
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 333564
Homologene: 46440
Tacc3
Name: transforming, acidic coiled-coil containing protein 3
Synonyms: Arnt interacting protein, Aint
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21335
Homologene: 81618
Or8k17
Name: olfactory receptor family 8 subfamily K member 17
Synonyms: GA_x6K02T2Q125-47716657-47715716, MOR187-2, Olfr1048
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259016
Or4f14b
Name: olfactory receptor family 4 subfamily F member 14B
Synonyms: GA_x6K02T2Q125-72988111-72987173, MOR245-19P, Olfr1307
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257956
Homologene: 128383
Ndufab1
Name: NADH:ubiquinone oxidoreductase subunit AB1
Synonyms: 9130423F15Rik, 2210401F17Rik, 2310039H15Rik, 8kDa, 2610003B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70316
HGNC: HGNC:7694
Homologene: 80336
Nckipsd
Name: NCK interacting protein with SH3 domain
Synonyms: WISH, SPIN90, AF3P21, ORF1, DIP1, Wasbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80987
Homologene: 9514
Tbx22
Name: T-box 22
Synonyms: D230020M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245572
Homologene: 9666
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 171,129,919 bp
  • A to G, chromosome 2 at 26,986,985 bp
  • A to G, chromosome 2 at 85,786,399 bp
  • A to C, chromosome 2 at 86,236,154 bp
  • A to G, chromosome 2 at 111,944,553 bp
  • A to G, chromosome 2 at 112,462,932 bp
  • A to T, chromosome 2 at 120,491,880 bp
  • G to A, chromosome 2 at 152,374,122 bp
  • C to A, chromosome 2 at 158,844,183 bp
  • C to G, chromosome 3 at 100,080,156 bp
  • G to A, chromosome 3 at 104,874,928 bp
  • T to C, chromosome 3 at 127,547,184 bp
  • C to T, chromosome 4 at 155,659,460 bp
  • T to C, chromosome 5 at 33,671,397 bp
  • A to G, chromosome 5 at 74,607,909 bp
  • T to C, chromosome 5 at 90,462,806 bp
  • C to T, chromosome 5 at 144,737,809 bp
  • G to T, chromosome 6 at 3,571,105 bp
  • G to A, chromosome 7 at 83,616,761 bp
  • A to G, chromosome 7 at 122,096,737 bp
  • A to T, chromosome 7 at 126,692,448 bp
  • A to T, chromosome 8 at 45,943,010 bp
  • G to A, chromosome 8 at 77,351,687 bp
  • A to T, chromosome 8 at 124,674,366 bp
  • A to G, chromosome 9 at 44,359,656 bp
  • A to G, chromosome 9 at 45,947,060 bp
  • T to C, chromosome 9 at 50,907,436 bp
  • G to A, chromosome 9 at 72,731,446 bp
  • A to G, chromosome 9 at 106,017,903 bp
  • C to A, chromosome 9 at 108,814,134 bp
  • G to A, chromosome 9 at 124,105,929 bp
  • A to G, chromosome 10 at 76,081,507 bp
  • T to A, chromosome 10 at 86,812,374 bp
  • A to G, chromosome 10 at 127,526,939 bp
  • A to G, chromosome 11 at 100,711,352 bp
  • A to T, chromosome 11 at 116,293,294 bp
  • T to A, chromosome 11 at 120,703,667 bp
  • AGAGTGAG to AGAGTGAGTGAG, chromosome 12 at 76,097,960 bp
  • T to C, chromosome 13 at 112,927,965 bp
  • T to C, chromosome 14 at 47,530,029 bp
  • T to G, chromosome 15 at 51,882,269 bp
  • T to C, chromosome 15 at 76,633,721 bp
  • T to C, chromosome 15 at 81,383,027 bp
  • A to G, chromosome 15 at 85,815,511 bp
  • A to G, chromosome 18 at 37,474,621 bp
  • A to G, chromosome 19 at 4,002,023 bp
  • T to A, chromosome 19 at 18,838,087 bp
  • G to A, chromosome 19 at 21,678,609 bp
  • T to C, chromosome X at 84,309,897 bp
  • A to T, chromosome X at 106,425,366 bp
  • G to A, chromosome X at 107,685,125 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0714 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038897-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.