Strain Name:
C57BL/6J-MtgxR0763Btlr/Mmmh
Stock Number:
038943-MU
Citation ID:
RRID:MMRRC_038943-MU
Other Names:
R0763 (G1), C57BL/6J-MtgxR0763Btlr
Major Collection:

Strain Information

Slc17a5
Name: solute carrier family 17 (anion/sugar transporter), member 5
Synonyms: 4631416G20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235504
Homologene: 56571
Ep400
Name: E1A binding protein p400
Synonyms: 1700020J09Rik, p400, mDomino
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75560
Homologene: 38779
Jade1
Name: jade family PHD finger 1
Synonyms: D530048A03Rik, Phf17
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269424
Homologene: 18162
Arhgdig
Name: Rho GDP dissociation inhibitor gamma
Synonyms: RIP2, Rho-GDI-3, Gdi5, Rho-GDI2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14570
HGNC: HGNC:680
Homologene: 7337
Ttc17
Name: tetratricopeptide repeat domain 17
Synonyms: 9130020K17Rik, D2Bwg1005e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74569
Homologene: 10100
Slc25a17
Name: solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
Synonyms: PMP34, 34kDa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20524
VEGA: 15
Homologene: 4637
Tomm70a
Name: translocase of outer mitochondrial membrane 70A
Synonyms: D16Ium22e, D16Wsu109e, D16Ium22, Tomm70a, Tom70, 2610044B22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 28185
VEGA: 16
Homologene: 40112
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: NMHC II-C, 2400004E04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71960
Homologene: 23480
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 2810013C04Rik, 5630401D06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Casc3
Name: exon junction complex subunit
Synonyms: Btz, Mln51
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192160
Homologene: 7208
Rbm10
Name: RNA binding motif protein 10
Synonyms: E430039K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 236732
HGNC: HGNC:9896
Homologene: 31330
Cep120
Name: centrosomal protein 120
Synonyms: Ccdc100
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225523
VEGA: 18
Homologene: 27415
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Cntrl
Name: centriolin
Synonyms: Cep1, Ma2a8, IB3/5, 6720467O09Rik, Cep110, b2b1468Clo
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26920
HGNC: HGNC:1858
Homologene: 38260
Tm7sf3
Name: transmembrane 7 superfamily member 3
Synonyms: 2010003B14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67623
Homologene: 9560
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Papln
Name: papilin, proteoglycan-like sulfated glycoprotein
Synonyms: E030033C16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 170721
Homologene: 71541
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Zbed5
Name: zinc finger BED-type containing 5
Synonyms: 2410018M08Rik, Chchd2l, Zbed5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71970
Homologene: 84838
Akap6
Name: A kinase anchor protein 6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Hps3
Name: HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
Synonyms: Hermansky-Pudlak syndrome 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12807
Homologene: 13019
Ttn
Name: titin
Synonyms: 2310036G12Rik, 2310057K23Rik, D330041I19Rik, mdm, connectin, D830007G01Rik, 1100001C23Rik, shru, 2310074I15Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Il12rb1
Name: interleukin 12 receptor, beta 1
Synonyms: CD212, IL-12R[b]
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16161
HGNC: HGNC:5971
Homologene: 4042
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319555
Homologene: 72261
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mass1, Gpr98, VLGR1, Mgr1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
BC016579
Name: cDNA sequence, BC016579
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212998
VEGA: 16
Homologene: 11622
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: Ccdc108, B230363K08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Tmem266
Name: transmembrane protein 266
Synonyms: AI118078
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244886
Homologene: 17551
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17837
HGNC: HGNC:9750
Homologene: 136663
Notch4
Name: notch 4
Synonyms: N4, Int-3, Int3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Mmp15
Name: matrix metallopeptidase 15
Synonyms: Membrane type 2-MMP, MT2-MMP
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17388
HGNC: HGNC:7161
Homologene: 20549
Palm2
Name: paralemmin 2
Synonyms: 53-H12, pEN70
Type: Gene
Species: Mouse
Chromosome: 4
Adam26b
Name: a disintegrin and metallopeptidase domain 26B
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382007
Homologene: 128363
Ifi44
Name: interferon-induced protein 44
Synonyms: p44, A430056A10Rik, MTAP44
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99899
Homologene: 4683
Atp8a1
Name: ATPase phospholipid transporting 8A1
Synonyms: Atp3a2, B230107D19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11980
Homologene: 48402
Foxred1
Name: FAD-dependent oxidoreductase domain containing 1
Synonyms: Tex23, TEG-23
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235169
Homologene: 9712
Socs4
Name: suppressor of cytokine signaling 4
Synonyms: 3110032M18Rik, A730004F22Rik, Socs7
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67296
Homologene: 15442
Spata31f1a
Name: spermatogenesis associated 31 subfamily F member 1A
Synonyms: Gm12429, Fam205a1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433698
Homologene: 79022
Abtb1
Name: ankyrin repeat and BTB domain containing 1
Synonyms: BPOZ, EF1ABP
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 80283
Homologene: 32731
Itgax
Name: integrin alpha X
Synonyms: CR4, Cd11c, CD11C (p150) alpha polypeptide
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Tchhl1
Name: trichohyalin-like 1
Synonyms: S100a17, Thhl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71325
Homologene: 84625
Ogfod1
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 1
Synonyms: 4930415J21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270086
Homologene: 41238
Ppp1r26
Name: protein phosphatase 1, regulatory subunit 26
Synonyms: LOC241289
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241289
Homologene: 49400
N4bp2l1
Name: NEDD4 binding protein 2-like 1
Synonyms: 2410024N18Rik, B230342M21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100637
Homologene: 14151
Tmem30c
Name: transmembrane protein 30C
Synonyms: 4933401B01Rik, 4933409A18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71027
Homologene: 78138
H2-Eb1
Name: histocompatibility 2, class II antigen E beta
Synonyms: Ia4, H-2Eb, Ia-4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14969
Homologene: 101524
Heatr3
Name: HEAT repeat containing 3
Synonyms: C030036P15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234549
Homologene: 45429
Foxl2
Name: forkhead box L2
Synonyms: Pfrk
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26927
HGNC: HGNC:1092
Homologene: 74992
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,904,682 bp
  • A to G, chromosome 1 at 158,509,890 bp
  • T to C, chromosome 2 at 28,450,367 bp
  • T to C, chromosome 2 at 35,171,066 bp
  • C to T, chromosome 2 at 76,731,190 bp
  • G to T, chromosome 2 at 94,332,803 bp
  • T to G, chromosome 3 at 20,003,279 bp
  • G to T, chromosome 3 at 41,613,783 bp
  • A to C, chromosome 3 at 93,471,571 bp
  • G to A, chromosome 3 at 151,749,498 bp
  • A to G, chromosome 4 at 42,851,238 bp
  • G to A, chromosome 4 at 48,392,628 bp
  • G to A, chromosome 4 at 57,688,441 bp
  • T to C, chromosome 5 at 67,659,883 bp
  • T to C, chromosome 5 at 110,665,837 bp
  • T to C, chromosome 5 at 121,307,033 bp
  • T to C, chromosome 5 at 129,902,179 bp
  • C to A, chromosome 5 at 150,594,404 bp
  • A to C, chromosome 6 at 88,838,279 bp
  • A to G, chromosome 6 at 122,075,294 bp
  • A to G, chromosome 6 at 146,606,289 bp
  • A to T, chromosome 7 at 44,665,367 bp
  • G to T, chromosome 7 at 73,447,274 bp
  • C to A, chromosome 7 at 128,147,940 bp
  • G to A, chromosome 8 at 17,027,284 bp
  • G to A, chromosome 8 at 43,520,564 bp
  • G to A, chromosome 8 at 70,813,290 bp
  • A to G, chromosome 8 at 72,671,044 bp
  • T to C, chromosome 8 at 88,158,241 bp
  • T to C, chromosome 8 at 94,055,636 bp
  • C to A, chromosome 8 at 95,368,228 bp
  • A to T, chromosome 9 at 35,207,473 bp
  • G to T, chromosome 9 at 55,414,955 bp
  • A to T, chromosome 9 at 78,553,090 bp
  • A to C, chromosome 9 at 98,956,033 bp
  • T to C, chromosome 11 at 66,155,530 bp
  • T to C, chromosome 11 at 98,831,318 bp
  • A to G, chromosome 12 at 53,142,214 bp
  • A to G, chromosome 12 at 83,791,865 bp
  • T to A, chromosome 13 at 81,499,125 bp
  • T to C, chromosome 14 at 47,290,655 bp
  • A to G, chromosome 15 at 81,323,706 bp
  • T to A, chromosome 16 at 45,629,455 bp
  • G to A, chromosome 16 at 57,122,172 bp
  • T to A, chromosome 16 at 57,270,176 bp
  • T to C, chromosome 17 at 26,200,301 bp
  • T to A, chromosome 17 at 34,314,159 bp
  • T to A, chromosome 17 at 34,565,332 bp
  • C to T, chromosome 17 at 67,772,818 bp
  • A to C, chromosome 18 at 53,721,737 bp
  • C to T, chromosome X at 20,637,664 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0763 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038943-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.