Strain Name:
C57BL/6J-MtgxR0799Btlr/Mmmh
Stock Number:
038979-MU
Citation ID:
RRID:MMRRC_038979-MU
Other Names:
R0799 (G1), C57BL/6J-MtgxR0799Btlr
Major Collection:

Gene Information

Sbf2
Name: SET binding factor 2
Synonyms: SBF2, 4833411B01Rik, mMTMH1, B430219L04Rik, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: GENA 60, GENA 47, Gena 52, Cyn, A730019I05Rik, WBE1, Whi, Todo, Obt, Mt, Lda, Flo, Edy, Dz, Cycn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320790
Homologene: 19067
Cdk4
Name: cyclin-dependent kinase 4
Synonyms: p34PSK-J3/cdk4, Crk3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12567
HGNC: HGNC:1773
Homologene: 55429
Xrn2
Name: 5'-3' exoribonuclease 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 24128
Homologene: 6927
Cct3
Name: chaperonin containing Tcp1, subunit 3 (gamma)
Synonyms: TriC-P5, Cctg, Tcp1-rs3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12462
HGNC: HGNC:1616
Homologene: 4373
Eps15l1
Name: epidermal growth factor receptor pathway substrate 15-like 1
Synonyms: Eps15R, 9830147J04Rik, Eps15-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13859
Homologene: 31881
Pxk
Name: PX domain containing serine/threonine kinase
Synonyms: C230080L11Rik, D14Ertd813e, MONaKA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218699
VEGA: 14
Homologene: 9828
Atad3a
Name: ATPase family, AAA domain containing 3A
Synonyms: Tob3, 2400004H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108888
Homologene: 10059
Htt
Name: huntingtin
Synonyms: huntingtin, HD, htt, IT15, C430023I11Rik, Hdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Gtpbp1
Name: GTP binding protein 1
Synonyms: GP-1, GTPBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14904
VEGA: 15
HGNC: HGNC:4669
Homologene: 3165
Abcf3
Name: ATP-binding cassette, sub-family F (GCN20), member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27406
HGNC: HGNC:72
Homologene: 22784
Kdm4a
Name: lysine (K)-specific demethylase 4A
Synonyms: Jmjd2, D4Ertd222e, JHDM3A, Jmjd2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230674
Homologene: 27780
Zfp345
Name: zinc finger protein 345
Synonyms: OTTMUSG00000015743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545471
Homologene: 134546
Smpd3
Name: sphingomyelin phosphodiesterase 3, neutral
Synonyms: neutral sphingomyelinase II, nSMase2, 4631433G07Rik, fro
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 58994
Homologene: 10260
Dach1
Name: dachshund family transcription factor 1
Synonyms: Dac, E130112M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13134
HGNC: HGNC:2663
Homologene: 7288
Epb41l4b
Name: erythrocyte membrane protein band 4.1 like 4b
Synonyms: Ehm2, D4Ertd346e, 6430543G08Rik, Lulu2, Epb4.1l4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54357
Homologene: 69270
Sppl2a
Name: signal peptide peptidase like 2A
Synonyms: C130089K23Rik, 2010106G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66552
Homologene: 36411
Adamts6
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
Synonyms: ADAM-TS6, A930019D11Rik, b2b2228Clo, b2b2187.1Clo, b2b2182Clo, b2b2029Clo, b2b1879.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 108154
VEGA: 13
HGNC: HGNC:222
Homologene: 82573
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Raf, Afr-1, Afr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 387609
Homologene: 8968
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268933
Homologene: 6870
Ampd3
Name: adenosine monophosphate deaminase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11717
HGNC: HGNC:470
Homologene: 408
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Mtr1, Ltrpc5, 9430099A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56843
Homologene: 22818
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Prss59
Name: protease, serine 59
Synonyms: Tryx5, 1700074P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73481
Homologene: 49905
Vmn2r88
Name: vomeronasal 2, receptor 88
Synonyms: V2r13, V2r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 669149
Homologene: 129606
Arntl2
Name: aryl hydrocarbon receptor nuclear translocator-like 2
Synonyms: BMAL2, 4632430A05Rik, MOP9, bHLHe6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 272322
Homologene: 10609
Slc5a4a
Name: solute carrier family 5, member 4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64452
VEGA: 10
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: B230399N07Rik, 4930532L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269610
Homologene: 56712
Rpp40
Name: ribonuclease P 40 subunit
Synonyms: D8Bwg1265e, Rnasep1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 208366
Homologene: 4836
Wdr90
Name: WD repeat domain 90
Synonyms: 3230401M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106618
Homologene: 27066
Dnlz
Name: DNL-type zinc finger
Synonyms: 1110034G11Rik, D2Bwg1335e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 52838
Homologene: 36864
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545477
Homologene: 129594
H2-M2
Name: histocompatibility 2, M region locus 2
Synonyms: H-2M2, Thy19.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14990
Homologene: 133732
Pacsin2
Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: Syndapin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 23970
VEGA: 15
HGNC: HGNC:8571
Homologene: 21414
Hip1r
Name: huntingtin interacting protein 1 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 29816
Homologene: 78348
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: LOC380973, 1700030F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72277
Gm9116
Name: predicted gene 9116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 668344
Fam83d
Name: family with sequence similarity 83, member D
Synonyms: 2310007D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71878
Homologene: 23715
Pkdcc
Name: protein kinase domain containing, cytoplasmic
Synonyms: ESTM17, Vlk, MAd1, Adtk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106522
Homologene: 18932
AI597479
Name: expressed sequence AI597479
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98404
Homologene: 11459
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Hgd
Name: homogentisate 1, 2-dioxygenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15233
HGNC: HGNC:4892
Homologene: 156
Pabpc1l
Name: poly(A) binding protein, cytoplasmic 1-like
Synonyms: ePAB, 1810053B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381404
Homologene: 77989
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74918
Homologene: 49784
4921539E11Rik
Name: RIKEN cDNA 4921539E11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 70941
Homologene: 52843
Zfp28
Name: zinc finger protein 28
Synonyms: mkr-5, Zfp-28, 2810438M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22690
Homologene: 69047
Ajm1
Name: apical junction component 1
Synonyms: LOC381353, Gm996
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381353
Homologene: 19943
Olfr911-ps1
Name: olfactory receptor 911, pseudogene 1
Synonyms: GA_x6K02T2PVTD-32247224-32248163, GA_x6K02T2PVTD-32223906-32224841, MOR166-1, MOR165-1, Olfr909
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258873
VEGA: 9
Homologene: 74148
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
4930555F03Rik
Name: RIKEN cDNA 4930555F03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75359
Poglut1
Name: protein O-glucosyltransferase 1
Synonyms: 9630046K23Rik, Ktelc1, Rumi, wsnp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224143
Homologene: 41353
Ube2e2
Name: ubiquitin-conjugating enzyme E2E 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218793
Homologene: 77337
Adgra2
Name: adhesion G protein-coupled receptor A2
Synonyms: Tem5, 9530074E10Rik, 8430414O08Rik, Gpr124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78560
Homologene: 13112
Trim35
Name: tripartite motif-containing 35
Synonyms: Mair, 0710005M05Rik, A430106H13Rik, Hls5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66854
Homologene: 134331
Tas2r134
Name: taste receptor, type 2, member 134
Synonyms: Tas2r34, T2R134
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 387511
Homologene: 66001
Crybb2
Name: crystallin, beta B2
Synonyms: betaB2-crystallin, Cryb-2, Aey2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12961
HGNC: HGNC:2398
Homologene: 420
Rabep2
Name: rabaptin, RAB GTPase binding effector protein 2
Synonyms: 2610011A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70314
Homologene: 23489
Hspa8
Name: heat shock protein 8
Synonyms: Hsp73, Hsc71, Hsc70, 2410008N15Rik, Hsc73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15481
HGNC: HGNC:5241
Homologene: 68524
Pcdhb20
Name: protocadherin beta 20
Synonyms: Pcdhb14, PcdhbT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93891
HGNC: HGNC:8685
Homologene: 134303
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 43,111,170 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • A to G, chromosome 2 at 25,578,562 bp
  • A to G, chromosome 2 at 26,351,473 bp
  • T to C, chromosome 2 at 51,628,373 bp
  • C to A, chromosome 2 at 126,920,307 bp
  • T to A, chromosome 2 at 147,029,898 bp
  • T to C, chromosome 2 at 150,472,351 bp
  • A to T, chromosome 2 at 153,992,272 bp
  • T to A, chromosome 2 at 158,779,888 bp
  • C to A, chromosome 2 at 164,031,214 bp
  • A to T, chromosome 3 at 88,299,345 bp
  • A to T, chromosome 3 at 93,910,465 bp
  • A to G, chromosome 4 at 8,801,310 bp
  • A to G, chromosome 4 at 57,086,003 bp
  • G to A, chromosome 4 at 103,242,904 bp
  • A to G, chromosome 4 at 118,146,992 bp
  • A to G, chromosome 4 at 152,384,159 bp
  • A to G, chromosome 4 at 155,747,470 bp
  • C to A, chromosome 5 at 34,817,753 bp
  • T to C, chromosome 5 at 113,062,171 bp
  • A to G, chromosome 5 at 123,996,941 bp
  • T to C, chromosome 5 at 150,560,193 bp
  • A to G, chromosome 6 at 40,928,599 bp
  • T to C, chromosome 6 at 146,823,253 bp
  • T to A, chromosome 7 at 6,384,183 bp
  • T to C, chromosome 7 at 110,341,355 bp
  • T to C, chromosome 7 at 110,800,697 bp
  • T to C, chromosome 7 at 126,438,724 bp
  • C to A, chromosome 7 at 143,078,351 bp
  • G to A, chromosome 8 at 27,112,495 bp
  • A to G, chromosome 8 at 49,495,439 bp
  • C to T, chromosome 8 at 72,346,085 bp
  • G to T, chromosome 8 at 106,264,789 bp
  • G to A, chromosome 9 at 38,524,141 bp
  • G to A, chromosome 9 at 40,803,841 bp
  • T to C, chromosome 10 at 76,176,534 bp
  • A to G, chromosome 10 at 127,064,994 bp
  • G to A, chromosome 12 at 81,722,269 bp
  • C to T, chromosome 13 at 35,902,051 bp
  • T to C, chromosome 13 at 104,314,271 bp
  • T to C, chromosome 14 at 8,148,123 bp
  • G to T, chromosome 14 at 18,630,393 bp
  • A to C, chromosome 14 at 51,414,502 bp
  • T to A, chromosome 14 at 66,309,201 bp
  • G to T, chromosome 14 at 98,168,615 bp
  • A to G, chromosome 15 at 48,185,384 bp
  • A to G, chromosome 15 at 57,821,313 bp
  • A to G, chromosome 15 at 79,716,200 bp
  • A to T, chromosome 15 at 83,379,797 bp
  • G to A, chromosome 15 at 99,942,012 bp
  • T to C, chromosome 16 at 20,559,334 bp
  • C to T, chromosome 16 at 37,628,609 bp
  • T to C, chromosome 16 at 38,534,721 bp
  • A to G, chromosome 17 at 25,826,128 bp
  • A to G, chromosome 17 at 25,860,130 bp
  • G to A, chromosome 17 at 37,482,749 bp
  • G to A, chromosome 17 at 83,223,918 bp
  • A to G, chromosome 18 at 37,505,885 bp
  • G to A, chromosome 19 at 6,386,018 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0799 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038979-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.