Strain Name:
C57BL/6J-MtgxR0838Btlr/Mmmh
Stock Number:
039017-MU
Citation ID:
RRID:MMRRC_039017-MU
Other Names:
R0838 (G1), C57BL/6J-MtgxR0838Btlr
Major Collection:

Strain Information

Ppm1a
Name: protein phosphatase 1A, magnesium dependent, alpha isoform
Synonyms: Mpp alpha, MMPa-2, MPPa-1, 2900017D14Rik, 2310003C21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19042
VEGA: 12
HGNC: HGNC:9275
Homologene: 56428
Rfx3
Name: regulatory factor X, 3 (influences HLA class II expression)
Synonyms: MRFX3, C230093O12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19726
HGNC: HGNC:9984
Homologene: 7917
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20513
VEGA: 10
Homologene: 21055
Sec24d
Name: SEC24 homolog D, COPII coat complex component
Synonyms: 2310020L09Rik, LOC383951
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69608
Homologene: 40986
2310057M21Rik
Name: RIKEN cDNA 2310057M21 gene
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68277
Homologene: 11793
Fkbp15
Name: FK506 binding protein 15
Synonyms: FKBP133, C430014M02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338355
Homologene: 28743
Npepps
Name: aminopeptidase puromycin sensitive
Synonyms: MP100, Psa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19155
HGNC: HGNC:7900
Homologene: 36199
Bard1
Name: BRCA1 associated RING domain 1
Synonyms: ENSMUSG00000060893, ENSMUSG00000073653
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12021
HGNC: HGNC:952
Homologene: 400
Pon1
Name: paraoxonase 1
Synonyms: Pon
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18979
HGNC: HGNC:9204
Homologene: 68058
Arrdc3
Name: arrestin domain containing 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105171
Homologene: 69318
Gga1
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 1
Synonyms: 4930406E12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106039
VEGA: 15
Homologene: 39250
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: RIM2, 2810036I15Rik, Syt3-rs
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 116838
VEGA: 15
Homologene: 81639
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Dedd2
Name: death effector domain-containing DNA binding protein 2
Synonyms: FLAME-3, 2410050E11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67379
Homologene: 23569
Arap1
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Synonyms: 2410002L19Rik, Centd2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69710
Homologene: 12326
Stard3nl
Name: STARD3 N-terminal like
Synonyms: 0610035N01Rik, 6530409L22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76205
Homologene: 11501
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: C330012F17Rik, D130005J21Rik, C130096N06Rik, GIV, HkRP1, Girdin, A430106J12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108686
Homologene: 41180
Slc15a4
Name: solute carrier family 15, member 4
Synonyms: C130069N12Rik, PTR4, PHT1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100561
Homologene: 26432
Jag1
Name: jagged 1
Synonyms: Serrate-1, Headturner, Htu, ABE2, Ozz, Gsfabe2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Adamts6
Name: ADAM metallopeptidase with thrombospondin type 1 motif 6
Synonyms: ADAM-TS6, A930019D11Rik, b2b1879.1Clo, b2b2228Clo, b2b2187.1Clo, b2b2182Clo, b2b2029Clo
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 108154
VEGA: 13
HGNC: HGNC:222
Homologene: 82573
Zscan10
Name: zinc finger and SCAN domain containing 10
Synonyms: Zscan10, Zfp206
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 332221
Homologene: 13122
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Lrp2bp
Name: Lrp2 binding protein
Synonyms: MegBP, 4930479L12Rik, 1700113N17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67620
Homologene: 10183
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Dpy19l1
Name: dpy-19 like C-mannosyltransferase 1
Synonyms: 1100001I19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244745
Homologene: 14762
Zdhhc8
Name: zinc finger, DHHC domain containing 8
Synonyms: D16H22S1738E, E330009O14Rik, Op53c05
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27801
VEGA: 16
Homologene: 8363
Myocd
Name: myocardin
Synonyms: Srfcp
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 214384
Homologene: 17043
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: CYLD1, 2010013M14Rik, C130039D01Rik, 2900009M21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Cd96
Name: CD96 antigen
Synonyms: Tactile, 1700109I12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 84544
Homologene: 68489
Map3k19
Name: mitogen-activated protein kinase kinase kinase 19
Synonyms: Ysk4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22625
Homologene: 19318
Zfp366
Name: zinc finger protein 366
Synonyms: DC-SCRIPT
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238803
Homologene: 17637
Tgtp1
Name: T cell specific GTPase 1
Synonyms: Mg21, Gtp2, Tgtp, Irgb6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21822
Homologene: 129991
Kcnh1
Name: potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms: ether a go-go, Eag1, Kv10.1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16510
HGNC: HGNC:6250
Homologene: 68242
Guk1
Name: guanylate kinase 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14923
HGNC: HGNC:4693
Homologene: 665
Slc28a3
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Synonyms: Cnt3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 114304
Homologene: 32533
Or51b17
Name: olfactory receptor family 51 subfamily B member 17
Synonyms: 5'[b]2, MOR1-2, GA_x6K02T2PBJ9-6648196-6649143, Olfr64
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18366
Homologene: 56593
Cilp2
Name: cartilage intermediate layer protein 2
Synonyms: CLIP-2, 1110031K21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68709
Homologene: 17713
Plscr4
Name: phospholipid scramblase 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235527
Homologene: 23217
Fam228a
Name: family with sequence similarity 228, member A
Synonyms: 4930417G10Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74855
VEGA: 12
Homologene: 54902
1110020G09Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Mixl1
Name: Mix paired-like homeobox
Synonyms: Mml
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27217
Homologene: 8445
Zfp69
Name: zinc finger protein 69
Synonyms: KRAB2, Zfp63, LOC381549
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381549
Homologene: 45693
Sult3a1
Name: sulfotransferase family 3A, member 1
Synonyms: Sultx2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57430
VEGA: 10
Homologene: 111031
Txndc16
Name: thioredoxin domain containing 16
Synonyms: 5730420B22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70561
Homologene: 18197
Ap5s1
Name: adaptor-related protein 5 complex, sigma 1 subunit
Synonyms: 0610038L13Rik, 2310035K24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69596
Homologene: 23095
Chit1
Name: chitinase 1
Synonyms: 2300002L19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71884
HGNC: HGNC:1936
Homologene: 68318
Amy2b
Name: amylase 2b
Synonyms: Amy-X, mAmy2-1, Amy2-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 545562
Orm1
Name: orosomucoid 1
Synonyms: Agp-2, Agp-1, Orm-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18405
Homologene: 130632
Gm4868
Name: predicted gene 4868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231736
Homologene: 138658
Nt5c1b
Name: 5'-nucleotidase, cytosolic IB
Synonyms: 4921514H13Rik, CN-IB
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70881
Homologene: 12370
Prl8a1
Name: prolactin family 8, subfamily a, member 1
Synonyms: PLP-Cd, 1600017L04Rik, 3830403L08Rik, Plpcd, Prlpc4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73244
Spata31d1e
Name: spermatogenesis associated 31 subfamily D, member 1E
Synonyms: 1700014D04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 102638268
Homologene: 140986
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 71,030,653 bp
  • C to A, chromosome 1 at 127,823,959 bp
  • T to A, chromosome 1 at 134,143,337 bp
  • A to T, chromosome 1 at 180,696,800 bp
  • A to G, chromosome 1 at 192,413,206 bp
  • A to G, chromosome 2 at 120,700,842 bp
  • G to A, chromosome 2 at 131,211,431 bp
  • G to A, chromosome 2 at 137,093,278 bp
  • T to A, chromosome 2 at 150,269,300 bp
  • T to C, chromosome 3 at 113,151,001 bp
  • T to A, chromosome 3 at 123,305,836 bp
  • G to T, chromosome 4 at 62,324,126 bp
  • A to G, chromosome 4 at 63,345,157 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • T to C, chromosome 4 at 120,931,281 bp
  • A to G, chromosome 5 at 125,848,623 bp
  • A to G, chromosome 5 at 127,617,003 bp
  • G to A, chromosome 6 at 5,175,758 bp
  • T to C, chromosome 7 at 25,211,187 bp
  • T to C, chromosome 7 at 101,400,412 bp
  • T to A, chromosome 7 at 103,893,415 bp
  • T to A, chromosome 7 at 131,361,806 bp
  • A to G, chromosome 8 at 46,025,124 bp
  • G to T, chromosome 8 at 69,881,719 bp
  • A to G, chromosome 8 at 88,741,350 bp
  • T to C, chromosome 9 at 24,432,431 bp
  • T to A, chromosome 9 at 92,471,760 bp
  • C to T, chromosome 10 at 33,879,288 bp
  • A to T, chromosome 10 at 78,796,222 bp
  • A to G, chromosome 11 at 29,400,285 bp
  • A to G, chromosome 11 at 48,987,143 bp
  • G to A, chromosome 11 at 59,185,095 bp
  • A to G, chromosome 11 at 65,178,932 bp
  • A to T, chromosome 11 at 97,267,692 bp
  • A to C, chromosome 11 at 115,998,162 bp
  • A to T, chromosome 11 at 118,060,104 bp
  • T to A, chromosome 12 at 4,735,002 bp
  • C to T, chromosome 12 at 10,375,071 bp
  • T to A, chromosome 12 at 72,784,320 bp
  • A to G, chromosome 13 at 19,372,586 bp
  • G to A, chromosome 13 at 27,574,025 bp
  • A to T, chromosome 13 at 58,588,269 bp
  • A to G, chromosome 13 at 59,742,468 bp
  • A to T, chromosome 13 at 80,889,247 bp
  • A to G, chromosome 13 at 99,228,610 bp
  • A to G, chromosome 13 at 104,413,789 bp
  • T to C, chromosome 14 at 45,165,419 bp
  • T to A, chromosome 15 at 9,091,242 bp
  • T to C, chromosome 15 at 39,681,025 bp
  • C to T, chromosome 15 at 78,891,918 bp
  • A to G, chromosome 16 at 18,224,566 bp
  • A to G, chromosome 16 at 46,117,926 bp
  • T to C, chromosome 17 at 23,610,034 bp
  • C to T, chromosome 19 at 27,849,967 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0838 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039017-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.