Strain Name:
C57BL/6J-MtgxR0839Btlr/Mmmh
Stock Number:
039018-MU
Citation ID:
RRID:MMRRC_039018-MU
Other Names:
R0839 (G1), C57BL/6J-MtgxR0839Btlr
Major Collection:

Gene Information

Cdk17
Name: cyclin-dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Rubcn
Name: RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
Synonyms: 1700021K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 100502698
Homologene: 15687
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100710
Homologene: 41001
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Zfp384
Name: zinc finger protein 384
Synonyms: C130073D16Rik, Ciz, Nmp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 269800
Homologene: 15849
Aco2
Name: aconitase 2, mitochondrial
Synonyms: Aco3, Aco-2, D10Wsu183e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11429
HGNC: HGNC:118
Homologene: 856
Mybl2
Name: myeloblastosis oncogene-like 2
Synonyms: Bmyb, B-Myb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17865
HGNC: HGNC:7548
Homologene: 1847
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 2410095B20Rik, 4931431C02Rik, C330023D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319899
VEGA: 9
Homologene: 83291
Cdc5l
Name: cell division cycle 5-like (S. pombe)
Synonyms: PCDC5RP, 1200002I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71702
VEGA: 17
HGNC: HGNC:1743
Homologene: 13291
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228850
Homologene: 10666
Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Synonyms: 1200015F06Rik, Mypt1, D10Ertd625e, 5730577I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17931
VEGA: 10
HGNC: HGNC:7618
Homologene: 1855
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Sos1
Name: SOS Ras/Rac guanine nucleotide exchange factor 1
Synonyms: 4430401P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20662
VEGA: 17
Homologene: 4117
Ptprc
Name: protein tyrosine phosphatase, receptor type, C
Synonyms: T200, B220, CD45, Lyt-4, Ly-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Pah
Name: phenylalanine hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18478
HGNC: HGNC:8582
Homologene: 234
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Pgam5
Name: phosphoglycerate mutase family member 5
Synonyms: 2610528A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72542
Homologene: 14597
Gle1
Name: GLE1 RNA export mediator (yeast)
Synonyms: 4933405K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74412
HGNC: HGNC:4315
Homologene: 20379
Nepro
Name: nucleolus and neural progenitor protein
Synonyms: BC027231
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 212547
Homologene: 9127
Dna2
Name: DNA replication helicase/nuclease 2
Synonyms: E130315B21Rik, Dna2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327762
HGNC: HGNC:2939
Homologene: 6124
Lct
Name: lactase
Synonyms: LOC226413, Lphl, LPH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226413
HGNC: HGNC:6530
Homologene: 124204
Ets1
Name: E26 avian leukemia oncogene 1, 5' domain
Synonyms: Ets-1, Tpl1, p51Ets-1, p42Ets-1, vs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23871
HGNC: HGNC:3488
Homologene: 3837
Abca4
Name: ATP-binding cassette, sub-family A (ABC1), member 4
Synonyms: Rim protein, RmP, Abc10, D430003I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Tapbp
Name: TAP binding protein
Synonyms: tapasin, TPN, D17Wsu91e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21356
Homologene: 2401
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: smMHC, SM2, SM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Ccdc73
Name: coiled-coil domain containing 73
Synonyms: 2210415I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211936
Homologene: 52235
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Olfr395
Name: olfactory receptor 395
Synonyms: GA_x6K02T2P1NL-4062605-4061667, MOR135-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259007
Eml1
Name: echinoderm microtubule associated protein like 1
Synonyms: ELP79, 1110008N23Rik, A930030P13Rik, heco
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68519
HGNC: HGNC:3330
Homologene: 20931
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: 1110008G13Rik, LOC100042382, Liprin-alpha4, Gm3812
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Ect2l
Name: epithelial cell transforming sequence 2 oncogene-like
Synonyms: Gm10331, C330021H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100045792
Homologene: 46005
Izumo1
Name: izumo sperm-egg fusion 1
Synonyms: 1700058F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73456
Homologene: 77701
Hltf
Name: helicase-like transcription factor
Synonyms: P113, Snf2l3, Smarca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20585
Homologene: 30136
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Col4a-1, Del(8)Bru44H, Del(8)44H, Bru, Svc, Raw, alpha1(IV) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224833
Homologene: 138294
Manea
Name: mannosidase, endo-alpha
Synonyms: 4932703L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242362
Homologene: 11636
Olfr967
Name: olfactory receptor 967
Synonyms: GA_x6K02T2PVTD-33447884-33448816, MOR171-30P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258086
VEGA: 9
HGNC: HGNC:8484
Homologene: 115535
Dgkz
Name: diacylglycerol kinase zeta
Synonyms: mDGK[z], E130307B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 104418
HGNC: HGNC:2857
Homologene: 37831
Nnt
Name: nicotinamide nucleotide transhydrogenase
Synonyms: 4930423F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18115
HGNC: HGNC:7863
Ankrd42
Name: ankyrin repeat domain 42
Synonyms: 4933417L02Rik, Ikbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73845
Homologene: 23652
Ube2l6
Name: ubiquitin-conjugating enzyme E2L 6
Synonyms: Ubcm8, 2810489I21Rik, UBCH8, RIG-B, Ubce8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56791
Homologene: 3112
Olfr144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226438
Homologene: 130054
Pla2g4b
Name: phospholipase A2, group IVB (cytosolic)
Synonyms: A030011C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211429
HGNC: HGNC:9036
Homologene: 3730
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: 4930415K13Rik, Rgsl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240816
Homologene: 129962
Plagl2
Name: pleiomorphic adenoma gene-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54711
HGNC: HGNC:9047
Homologene: 1994
Tmf1
Name: TATA element modulatory factor 1
Synonyms: LOC232286, 7030402D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232286
Homologene: 133801
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: 1110061H03Rik, SRRP129, CASP11, SIP1, 2610510E10Rik, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72193
VEGA: 15
Homologene: 37957
Scgb1b27
Name: secretoglobin, family 1B, member 27
Synonyms: Sal-1, Abp, Tcp, Abpa, Abpa27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11354
Homologene: 114479
Guk1
Name: guanylate kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14923
HGNC: HGNC:4693
Homologene: 665
Olfr1375
Name: olfactory receptor 1375
Synonyms: GA_x6K02T2QP88-4389999-4389056, MOR126-2, Olfr1375-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258509
Olfr237
Name: olfactory receptor 237
Synonyms: GA_x6K02T2P3E9-4404793-4403861, GA_x6K02T08UK8-1-481, MOR261-4, Olfr438, Olfr237-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258648
Homologene: 88438
Tmem33
Name: transmembrane protein 33
Synonyms: 5430406L04Rik, 2410089A21Rik, 2700052H22Rik, 1600019D15Rik, 1110006G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67878
Homologene: 10018
Olfr735
Name: olfactory receptor 735
Synonyms: GA_x6K02T2PMLR-6042130-6041183, MOR243-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 257909
Homologene: 71977
Olfr311
Name: olfactory receptor 311
Synonyms: GA_x6K02T2NKPP-565870-564944, MOR222-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258530
Homologene: 77375
Duoxa1
Name: dual oxidase maturation factor 1
Synonyms: Nip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 213696
Homologene: 16043
H2-Q7
Name: histocompatibility 2, Q region locus 7
Synonyms: H-2Q7, Qa-7, Qa7, Ped
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15018
HGNC: HGNC:4931
Homologene: 128352
Syf2
Name: SYF2 homolog, RNA splicing factor (S. cerevisiae)
Synonyms: p29, mp29, 1110018L13Rik, D4Bwg1551e, Gcipip, Cbpin, Ntc31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68592
Homologene: 5993
Kap
Name: kidney androgen regulated protein
Synonyms: kidney androgen-regulated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16483
Homologene: 49244
Gm10118
Name: predicted gene 10118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Kctd20
Name: potassium channel tetramerisation domain containing 20
Synonyms: D17Ertd562e, 2410004N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66989
Homologene: 12063
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 128,286,609 bp
  • A to T, chromosome 1 at 134,328,807 bp
  • A to G, chromosome 1 at 135,954,680 bp
  • A to G, chromosome 1 at 138,101,132 bp
  • A to G, chromosome 1 at 153,802,234 bp
  • T to A, chromosome 2 at 29,958,450 bp
  • T to C, chromosome 2 at 52,277,548 bp
  • T to C, chromosome 2 at 84,802,770 bp
  • A to G, chromosome 2 at 91,935,111 bp
  • A to T, chromosome 2 at 104,991,097 bp
  • T to A, chromosome 2 at 120,034,681 bp
  • A to G, chromosome 2 at 122,306,380 bp
  • C to A, chromosome 2 at 153,232,541 bp
  • T to C, chromosome 2 at 158,473,283 bp
  • T to C, chromosome 2 at 163,075,768 bp
  • T to C, chromosome 3 at 20,106,541 bp
  • G to A, chromosome 3 at 122,126,878 bp
  • T to C, chromosome 4 at 26,327,983 bp
  • T to A, chromosome 4 at 134,936,063 bp
  • T to A, chromosome 5 at 67,264,308 bp
  • A to T, chromosome 5 at 110,267,130 bp
  • G to T, chromosome 5 at 150,764,962 bp
  • T to A, chromosome 6 at 43,153,624 bp
  • T to C, chromosome 6 at 83,190,477 bp
  • A to G, chromosome 6 at 97,176,323 bp
  • C to A, chromosome 6 at 125,036,668 bp
  • T to C, chromosome 6 at 133,851,914 bp
  • A to G, chromosome 7 at 34,021,851 bp
  • T to A, chromosome 7 at 45,627,112 bp
  • T to C, chromosome 7 at 92,612,772 bp
  • G to A, chromosome 8 at 11,221,015 bp
  • T to C, chromosome 9 at 21,817,892 bp
  • T to A, chromosome 9 at 32,734,061 bp
  • A to T, chromosome 9 at 39,237,850 bp
  • A to T, chromosome 9 at 39,750,391 bp
  • A to T, chromosome 9 at 53,545,180 bp
  • T to C, chromosome 9 at 67,898,738 bp
  • A to G, chromosome 10 at 18,141,904 bp
  • T to C, chromosome 10 at 62,969,782 bp
  • T to G, chromosome 10 at 63,926,864 bp
  • C to A, chromosome 10 at 74,626,782 bp
  • C to T, chromosome 10 at 76,477,917 bp
  • T to C, chromosome 10 at 87,522,062 bp
  • A to G, chromosome 10 at 93,224,932 bp
  • T to C, chromosome 10 at 108,198,861 bp
  • A to G, chromosome 11 at 51,048,427 bp
  • G to A, chromosome 11 at 58,841,652 bp
  • G to A, chromosome 11 at 59,185,095 bp
  • T to A, chromosome 11 at 73,907,312 bp
  • A to G, chromosome 12 at 108,512,960 bp
  • A to T, chromosome 13 at 119,394,656 bp
  • A to G, chromosome 14 at 50,346,088 bp
  • A to G, chromosome 15 at 8,145,587 bp
  • A to G, chromosome 15 at 81,907,535 bp
  • A to G, chromosome 15 at 96,423,553 bp
  • C to T, chromosome 16 at 14,203,178 bp
  • A to C, chromosome 16 at 32,827,343 bp
  • C to A, chromosome 16 at 44,736,019 bp
  • A to T, chromosome 17 at 28,957,898 bp
  • T to C, chromosome 17 at 33,925,743 bp
  • A to G, chromosome 17 at 35,439,712 bp
  • A to C, chromosome 17 at 45,393,147 bp
  • A to T, chromosome 17 at 47,436,827 bp
  • A to T, chromosome 17 at 80,433,730 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0839 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039018-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.