Strain Name:
C57BL/6J-MtgxR0847Btlr/Mmmh
Stock Number:
039026-MU
Citation ID:
RRID:MMRRC_039026-MU
Other Names:
R0847 (G1), C57BL/6J-MtgxR0847Btlr
Major Collection:

Gene Information

Slc26a5
Name: solute carrier family 26, member 5
Synonyms: prestin, Pres
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 80979
HGNC: HGNC:9359
Homologene: 69472
Slc27a4
Name: solute carrier family 27 (fatty acid transporter), member 4
Synonyms: fatty acid transport protein 4, FATP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 26569
Homologene: 68437
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Rprd2
Name: regulation of nuclear pre-mRNA domain containing 2
Synonyms: 6720469I21Rik, 4930535B03Rik, 2810036A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75137
Homologene: 19997
Sacm1l
Name: SAC1 suppressor of actin mutations 1-like (yeast)
Synonyms: Sac1p, SAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83493
VEGA: 9
Homologene: 6320
Ube3a
Name: ubiquitin protein ligase E3A
Synonyms: 5830462N02Rik, A130086L21Rik, E6-AP ubiquitin protein ligase, Hpve6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22215
Homologene: 7988
Rpap3
Name: RNA polymerase II associated protein 3
Synonyms: 2310042P20Rik, D15Ertd682e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71919
VEGA: 15
Homologene: 11613
Ints12
Name: integrator complex subunit 12
Synonyms: 1110020M19Rik, A230056J18Rik, 4930529N21Rik, Phf22, 2810027J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71793
Homologene: 32474
Tnfrsf21
Name: tumor necrosis factor receptor superfamily, member 21
Synonyms: DR6, Death receptor 6, TR7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 94185
VEGA: 17
Homologene: 8696
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230249
Homologene: 6056
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Tbr1
Name: T-box brain gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 21375
Homologene: 4807
Fxyd7
Name: FXYD domain-containing ion transport regulator 7
Synonyms: 1110035I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57780
HGNC: HGNC:4034
Homologene: 11091
Cep63
Name: centrosomal protein 63
Synonyms: ET2, D9Mgc41, CD20R, D9Mgc48e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 28135
Homologene: 11861
Tln1
Name: talin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21894
Homologene: 21267
Kdm4a
Name: lysine (K)-specific demethylase 4A
Synonyms: D4Ertd222e, Jmjd2a, Jmjd2, JHDM3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230674
Homologene: 27780
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: 9830168K16Rik, Trrp7, TRPC7, LTRPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 28240
Homologene: 20709
Med20
Name: mediator complex subunit 20
Synonyms: 2410115I17Rik, Trfp, 1110011O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 56771
Homologene: 3158
Pthlh
Name: parathyroid hormone-like peptide
Synonyms: parathyroid hormone-related protein, Pthrp, PTH-like, parathyroid hormone-like hormone, PTH-related peptide, parathyroid hormone-related peptide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19227
HGNC: HGNC:9607
Homologene: 2113
Ccn4
Name: cellular communication network factor 4
Synonyms: CCN4, Wisp1, Elm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22402
Homologene: 2883
Chia1
Name: chitinase, acidic 1
Synonyms: YNL, Chia, AMCase, 2200003E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 81600
Homologene: 75168
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269902
HGNC: null
Homologene: 104832
Nav3
Name: neuron navigator 3
Synonyms: 9630020C08Rik, Pomfil1p, 4732483H20Rik, unc53H3, steerin 3, POMFIL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 260315
Homologene: 56688
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Gpn2
Name: GPN-loop GTPase 2
Synonyms: Atpbd1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100210
Homologene: 7006
Olfm2
Name: olfactomedin 2
Synonyms: A030009A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244723
VEGA: 9
Homologene: 14380
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 192188
Homologene: 23022
Synm
Name: synemin, intermediate filament protein
Synonyms: Synemin, 4930412K21Rik, Dmn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233335
Homologene: 9081
Abcb1b
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Synonyms: Pgy-1, Mdr1, Abcb1, Mdr1b, mdr, Pgy1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18669
HGNC: null
Homologene: 69084
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 1110004P15Rik, 2310047C17Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Kremen2
Name: kringle containing transmembrane protein 2
Synonyms: Krm2, 2900054E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73016
VEGA: 17
Homologene: 65132
Sobp
Name: sine oculis binding protein
Synonyms: jc, Jxc1, 5330439J01Rik, 2900009C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 109205
Homologene: 41216
Olfr1453
Name: olfactory receptor 1453
Synonyms: GA_x6K02T2RE5P-3357666-3356743, MOR202-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258695
HGNC: null
Homologene: 120159
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: 6720489L24Rik, Adp, Mdga2, 9330209L04Rik, Tg(Prnp-PFN1*G118V)838Kiaei, Mamdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 320772
Homologene: 45659
Spata7
Name: spermatogenesis associated 7
Synonyms: B230306G18Rik, HSD3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104871
Homologene: 10189
Myo18b
Name: myosin XVIIIb
Synonyms: 4933411E19Rik, 4932408L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74376
Homologene: 53435
Olfr1487
Name: olfactory receptor 1487
Synonyms: GA_x6K02T2RE5P-3951719-3952666, MOR202-18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258629
HGNC: null
Homologene: 110492
Tmprss11g
Name: transmembrane protease, serine 11g
Synonyms: Desc4, 9930032O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320454
Homologene: 82239
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: 1600029H12Rik, Psg30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73250
HGNC: null
Homologene: 115938
Exosc3
Name: exosome component 3
Synonyms: 2310005D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66362
Homologene: 6867
Cblc
Name: Casitas B-lineage lymphoma c
Synonyms: 2310076I21Rik, Cbl3, 2310079L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 80794
Homologene: 8108
Olfr810
Name: olfactory receptor 810
Synonyms: GA_x6K02T2PULF-11470271-11469333, MOR113-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258543
Homologene: 46347
Tmem167b
Name: transmembrane protein 167B
Synonyms: 2010200O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67495
Homologene: 10594
Sri
Name: sorcin
Synonyms: 2900070H08Rik, 2210417O06Rik, Sor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 109552
Homologene: 37736
Arhgap8
Name: Rho GTPase activating protein 8
Synonyms: 3110043J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73167
Homologene: 23645
Gm17349
Name: predicted gene, 17349
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 2 at 29,811,249 bp
  • T to C, chromosome 2 at 61,805,029 bp
  • A to G, chromosome 3 at 95,765,413 bp
  • A to T, chromosome 3 at 106,131,937 bp
  • C to T, chromosome 3 at 108,560,221 bp
  • C to T, chromosome 3 at 133,108,842 bp
  • A to G, chromosome 4 at 43,555,333 bp
  • A to G, chromosome 4 at 45,319,695 bp
  • G to A, chromosome 4 at 58,841,439 bp
  • C to T, chromosome 4 at 118,164,498 bp
  • A to T, chromosome 4 at 123,399,366 bp
  • A to G, chromosome 4 at 133,588,595 bp
  • G to A, chromosome 5 at 8,063,755 bp
  • T to C, chromosome 5 at 8,845,764 bp
  • A to T, chromosome 5 at 21,837,866 bp
  • T to C, chromosome 5 at 86,490,726 bp
  • T to C, chromosome 5 at 112,874,488 bp
  • A to T, chromosome 6 at 147,263,268 bp
  • A to G, chromosome 7 at 17,757,837 bp
  • A to T, chromosome 7 at 19,790,534 bp
  • A to G, chromosome 7 at 31,044,604 bp
  • A to T, chromosome 7 at 41,428,801 bp
  • G to A, chromosome 7 at 59,276,586 bp
  • T to C, chromosome 7 at 67,735,056 bp
  • A to G, chromosome 7 at 119,955,996 bp
  • A to G, chromosome 9 at 20,668,657 bp
  • A to T, chromosome 9 at 54,405,828 bp
  • A to G, chromosome 9 at 102,588,758 bp
  • G to A, chromosome 9 at 123,548,862 bp
  • C to G, chromosome 10 at 43,022,419 bp
  • C to T, chromosome 10 at 77,929,288 bp
  • T to C, chromosome 10 at 86,969,871 bp
  • T to A, chromosome 10 at 109,903,857 bp
  • T to A, chromosome 10 at 129,791,458 bp
  • T to A, chromosome 12 at 66,723,080 bp
  • T to A, chromosome 12 at 98,648,430 bp
  • T to G, chromosome 15 at 66,919,275 bp
  • T to A, chromosome 15 at 84,771,775 bp
  • C to T, chromosome 15 at 97,703,201 bp
  • C to A, chromosome 15 at 99,702,408 bp
  • G to T, chromosome 17 at 23,744,660 bp
  • C to T, chromosome 17 at 43,038,213 bp
  • G to A, chromosome 17 at 47,611,693 bp
  • C to T, chromosome 19 at 9,006,433 bp
  • A to T, chromosome 19 at 13,027,731 bp
  • C to T, chromosome 19 at 13,619,551 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0847 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039026-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.