Strain Name:
C57BL/6J-MtgxR0882Btlr/Mmmh
Stock Number:
039049-MU
Citation ID:
RRID:MMRRC_039049-MU
Other Names:
R0882 (G1), C57BL/6J-MtgxR0882Btlr
Major Collection:

Gene Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231051
Homologene: 46480
Mc3r
Name: melanocortin 3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17201
HGNC: HGNC:6931
Homologene: 7412
Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, bNOS, Nos-1, NO, 2310005C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Pdia3
Name: protein disulfide isomerase associated 3
Synonyms: ERp61, ERp60, ERp57, PDI-Q2, Plca, Erp, Grp58, PDI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14827
HGNC: HGNC:4606
Homologene: 68454
Aasdh
Name: aminoadipate-semialdehyde dehydrogenase
Synonyms: A230062G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231326
Homologene: 71711
Srgap2
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: FBP2, 9930124L22Rik, Fnbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14270
Homologene: 52683
Apbb2
Name: amyloid beta (A4) precursor protein-binding, family B, member 2
Synonyms: TR2L, Rirl1, 2310007D03Rik, Zfra, FE65L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11787
HGNC: HGNC:582
Homologene: 32079
Vps53
Name: VPS53 GARP complex subunit
Synonyms: 2310040I21Rik, 2010002A08Rik, 3100002B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68299
Homologene: 6264
Cep68
Name: centrosomal protein 68
Synonyms: 6030463E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216543
Homologene: 65235
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Pot1b
Name: protection of telomeres 1B
Synonyms: 2810458H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72836
VEGA: 17
Homologene: 87058
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: 6720464I07Rik, Solo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223435
VEGA: 15
Homologene: 20847
Ctla4
Name: cytotoxic T-lymphocyte-associated protein 4
Synonyms: Ctla-4, Ly-56, Cd152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12477
HGNC: HGNC:2505
Homologene: 3820
Nfix
Name: nuclear factor I/X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18032
HGNC: HGNC:7788
Homologene: 1872
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, MSws, Nte
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50767
Homologene: 21333
Zc2hc1a
Name: zinc finger, C2HC-type containing 1A
Synonyms: 3110050N22Rik, Fam164a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67306
Homologene: 9338
Slc25a20
Name: solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
Synonyms: mCAC, Cact, 1110007P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57279
HGNC: HGNC:1421
Homologene: 331
Prss57
Name: protease, serine 57
Synonyms: GLGL782, UNQ782, 2900092M14Rik, Prssl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73106
Homologene: 133812
Pkp2
Name: plakophilin 2
Synonyms: 1200012P04Rik, 1200008D14Rik, Pkp2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67451
HGNC: HGNC:9024
Homologene: 3364
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: (alpha)1 subunit, Cchl1a1, Cav1.2, L-type Cav1.2, D930026N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, D430038H04Rik, 9430076A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Gdpd4
Name: glycerophosphodiester phosphodiesterase domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233537
Homologene: 18606
Vars2
Name: valyl-tRNA synthetase 2, mitochondrial
Synonyms: 1190004I24Rik, Vars2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68915
Homologene: 57502
Agap2
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Synonyms: Centg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216439
VEGA: 10
Homologene: 86815
Olfr151
Name: olfactory receptor 151
Synonyms: M71, MOR171-2, GA_x6K02T2PVTD-31408136-31407207
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 406176
HGNC: HGNC:8469
Homologene: 12726
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086, AI414108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235086
Homologene: 19472
Fam209
Name: family with sequence similarity 209
Synonyms: 1700029J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76426
Homologene: 19218
Zfp820
Name: zinc finger protein 820
Synonyms: 2610036F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75424
VEGA: 17
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: 1110061H03Rik, SRRP129, CASP11, SIP1, 2610510E10Rik, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72193
VEGA: 15
Homologene: 37957
Gtf3c4
Name: general transcription factor IIIC, polypeptide 4
Synonyms: KAT12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269252
HGNC: HGNC:4667
Homologene: 8147
Gabbr2
Name: gamma-aminobutyric acid (GABA) B receptor, 2
Synonyms: Gababr2, LOC242425, Gpr51, GB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Pcdhb12
Name: protocadherin beta 12
Synonyms: Pcdhb5F, PcdhbL, Pcdh3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93883
Homologene: 87126
Gm4841
Name: predicted gene 4841
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225594
VEGA: 18
Alcam
Name: activated leukocyte cell adhesion molecule
Synonyms: DM-GRASP, CD166, MuSC, SC1, BEN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11658
HGNC: HGNC:400
Homologene: 1229
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Thoc2l
Name: THO complex subunit 2-like
Synonyms: Gm3179, BC005561
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100042165
Myb
Name: myeloblastosis oncogene
Synonyms: c-myb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17863
HGNC: HGNC:7545
Homologene: 31311
Vmn2r109
Name: vomeronasal 2, receptor 109
Synonyms: EG627814
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627814
Homologene: 129678
Adh1
Name: alcohol dehydrogenase 1 (class I)
Synonyms: ADH-AA, class I alcohol dehydrogenase, Adh-1-t, Adh-1t, Adh-1, Adh1-t, Adh1-e, Adh1tl, Adh-1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11522
Homologene: 73888
Zhx3
Name: zinc fingers and homeoboxes 3
Synonyms: 4932418O04Rik, 1810059C13Rik, 9530010N21Rik, Tix1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320799
Homologene: 9000
Olfr586
Name: olfactory receptor 586
Synonyms: GA_x6K02T2PBJ9-5836380-5835439, MOR8-2, MOR8-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259115
Homologene: 131143
Sorbs3
Name: sorbin and SH3 domain containing 3
Synonyms: SH3P3, vinexin alpha, vinexin beta, Sh3d4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20410
VEGA: 14
Homologene: 4218
Lrwd1
Name: leucine-rich repeats and WD repeat domain containing 1
Synonyms: 1200011O22Rik, Orca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71735
Homologene: 17678
Prr5l
Name: proline rich 5 like
Synonyms: 4833411O04Rik, 2600010E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72446
Homologene: 11753
Plekha3
Name: pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
Synonyms: FAPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 83435
Homologene: 10417
Gm20628
Name: predicted gene 20628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Tmem109
Name: transmembrane protein 109
Synonyms: 1110006I15Rik, mitsugumin23, MG23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68539
Homologene: 11458
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 46,340,132 bp
  • T to C, chromosome 1 at 60,909,238 bp
  • A to T, chromosome 1 at 131,289,515 bp
  • A to T, chromosome 2 at 28,834,770 bp
  • G to A, chromosome 2 at 76,682,798 bp
  • T to C, chromosome 2 at 101,758,541 bp
  • G to A, chromosome 2 at 121,432,377 bp
  • A to C, chromosome 2 at 160,780,709 bp
  • A to G, chromosome 2 at 172,249,791 bp
  • G to T, chromosome 2 at 172,472,635 bp
  • G to A, chromosome 3 at 7,526,362 bp
  • G to A, chromosome 3 at 96,269,744 bp
  • A to T, chromosome 3 at 138,286,797 bp
  • A to G, chromosome 4 at 46,718,904 bp
  • T to C, chromosome 5 at 25,295,607 bp
  • T to A, chromosome 5 at 66,400,255 bp
  • G to A, chromosome 5 at 76,876,283 bp
  • T to C, chromosome 5 at 104,519,009 bp
  • T to C, chromosome 5 at 117,947,447 bp
  • T to C, chromosome 5 at 136,123,400 bp
  • C to T, chromosome 6 at 118,612,625 bp
  • T to C, chromosome 7 at 97,966,298 bp
  • A to C, chromosome 7 at 103,122,575 bp
  • T to C, chromosome 8 at 3,517,081 bp
  • T to C, chromosome 8 at 84,727,925 bp
  • A to G, chromosome 9 at 16,031,368 bp
  • T to C, chromosome 9 at 27,319,316 bp
  • T to C, chromosome 9 at 37,711,872 bp
  • T to A, chromosome 9 at 108,681,990 bp
  • T to C, chromosome 10 at 21,156,360 bp
  • A to G, chromosome 10 at 74,342,656 bp
  • G to A, chromosome 10 at 79,785,865 bp
  • A to G, chromosome 10 at 127,087,450 bp
  • T to C, chromosome 11 at 20,239,393 bp
  • A to G, chromosome 11 at 76,082,659 bp
  • A to T, chromosome 14 at 30,892,274 bp
  • T to A, chromosome 14 at 70,207,572 bp
  • A to T, chromosome 15 at 27,732,894 bp
  • G to T, chromosome 15 at 96,418,295 bp
  • C to A, chromosome 16 at 16,269,711 bp
  • T to C, chromosome 16 at 52,253,210 bp
  • A to G, chromosome 17 at 20,554,580 bp
  • A to G, chromosome 17 at 21,823,836 bp
  • T to C, chromosome 17 at 35,657,299 bp
  • C to T, chromosome 17 at 55,666,400 bp
  • C to A, chromosome 18 at 37,437,322 bp
  • C to T, chromosome 18 at 60,269,780 bp
  • C to T, chromosome 18 at 88,973,689 bp
  • T to C, chromosome 19 at 10,871,841 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0882 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039049-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.