Strain Name:
C57BL/6J-MtgxR0939Btlr/Mmmh
Stock Number:
039078-MU
Citation ID:
RRID:MMRRC_039078-MU
Other Names:
R0939 (G1), C57BL/6J-MtgxR0939Btlr
Major Collection:

Gene Information

Dst
Name: dystonin
Synonyms: ah, athetoid, nmf203, Bpag1, nmf339, A830042E19Rik, bullous pemphigoid antigen 1, Macf2, BPAG1, BPAG1-n, bullous pemphigoid antigen 1, Bpag, 2310001O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Grg1, C230057C06Rik, Estm14, Tle4l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21885
Homologene: 21058
Bicd1
Name: BICD cargo adaptor 1
Synonyms: B830009D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12121
HGNC: HGNC:1049
Homologene: 37518
Rif1
Name: replication timing regulatory factor 1
Synonyms: D2Ertd145e, 6530403D07Rik, 5730435J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223435
VEGA: 15
Homologene: 20847
Rreb1
Name: ras responsive element binding protein 1
Synonyms: 1110037N09Rik, B930013M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68750
Homologene: 2218
Cdcp1
Name: CUB domain containing protein 1
Synonyms: E030027H19Rik, 9030022E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109332
Homologene: 11276
Eapp
Name: E2F-associated phosphoprotein
Synonyms: 1810011O16Rik, EAPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66266
Homologene: 10206
Ssh1
Name: slingshot protein phosphatase 1
Synonyms: mSSH-1L, LOC384311
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231637
Homologene: 41299
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Dach1
Name: dachshund family transcription factor 1
Synonyms: Dac, E130112M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13134
HGNC: HGNC:2663
Homologene: 7288
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: b2b1289Clo, b2b1727Clo, lrd, b2b1279Clo, avc4, b2b598Clo, Dnahc11, b2b1203Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Spocd1
Name: SPOC domain containing 1
Synonyms: OTTMUSG00000009522
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 622480
Homologene: 83439
Cfap53
Name: cilia and flagella associated protein 53
Synonyms: Ccdc11, 4933415I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 74453
Homologene: 27056
Cacna1b
Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms: Cchn1a, Cav2.2, alpha(1B)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12287
HGNC: HGNC:1389
Homologene: 20184
Slc25a39
Name: solute carrier family 25, member 39
Synonyms: 3010027G13Rik, D11Ertd333e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68066
Homologene: 69200
Npr2
Name: natriuretic peptide receptor 2
Synonyms: pwe, cn, guanylyl cyclase-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Olfr1564
Name: olfactory receptor 1564
Synonyms: Gm4461
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100043474
Homologene: 133726
Prss1
Name: protease, serine 1 (trypsin 1)
Synonyms: Try1, Trygn16, PRSS1, Try-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 114228
Homologene: 88408
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320277
Homologene: 23371
Tubb1
Name: tubulin, beta 1 class VI
Synonyms: 2810484G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545486
Homologene: 69474
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Wiz
Name: widely-interspaced zinc finger motifs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22404
Homologene: 7997
Gnmt
Name: glycine N-methyltransferase
Synonyms: glycine N methyl transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14711
HGNC: HGNC:4415
Homologene: 7741
Olfr1013
Name: olfactory receptor 1013
Synonyms: MOR213-2, GA_x6K02T2Q125-47248551-47249468
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258757
Homologene: 74096
Slfn5
Name: schlafen 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327978
Homologene: 18839
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233445
Homologene: 115466
AC238840.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Olfr516
Name: olfactory receptor 516
Synonyms: GA_x6K02T2PBJ9-11176324-11175380, MOR268-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258720
HGNC: HGNC:8162
Homologene: 138316
Igdcc4
Name: immunoglobulin superfamily, DCC subclass, member 4
Synonyms: WI-18508, 9330155G14Rik, Nope, WI-16786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56741
VEGA: 9
Homologene: 10570
Plcxd3
Name: phosphatidylinositol-specific phospholipase C, X domain containing 3
Synonyms: B130016O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239318
Homologene: 45574
Esd
Name: esterase D/formylglutathione hydrolase
Synonyms: Esd, Es10, Es-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13885
HGNC: HGNC:3465
Homologene: 55623
Rbms3
Name: RNA binding motif, single stranded interacting protein
Synonyms: 8430436O14Rik, 6720477E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 207181
Homologene: 49388
Speer4f2
Name: spermatogenesis associated glutamate (E)-rich protein 4f2
Synonyms: Gm3495, Gm3535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100041749
Gm525
Name: predicted gene 525
Synonyms: LOC217071
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217071
Homologene: 129636
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 34,244,383 bp
  • A to G, chromosome 2 at 24,679,654 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to A, chromosome 2 at 85,770,653 bp
  • G to A, chromosome 2 at 174,455,756 bp
  • A to G, chromosome 4 at 43,650,499 bp
  • A to G, chromosome 4 at 72,118,534 bp
  • A to T, chromosome 4 at 129,948,870 bp
  • A to G, chromosome 5 at 17,374,404 bp
  • A to G, chromosome 5 at 113,970,436 bp
  • A to C, chromosome 6 at 41,463,588 bp
  • A to T, chromosome 6 at 121,884,349 bp
  • A to T, chromosome 6 at 149,409,648 bp
  • T to C, chromosome 7 at 38,568,932 bp
  • T to C, chromosome 7 at 44,506,887 bp
  • A to T, chromosome 7 at 85,623,681 bp
  • T to A, chromosome 7 at 108,845,233 bp
  • T to A, chromosome 9 at 65,131,473 bp
  • C to T, chromosome 9 at 117,109,960 bp
  • A to G, chromosome 9 at 123,183,690 bp
  • G to T, chromosome 11 at 82,961,338 bp
  • C to A, chromosome 11 at 89,075,102 bp
  • T to C, chromosome 11 at 102,405,051 bp
  • C to T, chromosome 11 at 120,012,143 bp
  • TTTCTTCTTCTTCTTCTT to TTTCTTCTTCTTCTT, chromosome 12 at 54,685,949 bp
  • C to T, chromosome 12 at 118,060,407 bp
  • A to G, chromosome 13 at 37,932,231 bp
  • C to A, chromosome 14 at 74,736,027 bp
  • A to G, chromosome 14 at 84,447,755 bp
  • A to G, chromosome 14 at 97,915,924 bp
  • T to A, chromosome 15 at 4,516,862 bp
  • A to T, chromosome 15 at 9,704,550 bp
  • A to G, chromosome 15 at 27,741,250 bp
  • T to C, chromosome 17 at 32,387,567 bp
  • T to C, chromosome 17 at 33,215,661 bp
  • A to G, chromosome 17 at 46,726,345 bp
  • A to G, chromosome 18 at 74,305,730 bp
  • A to T, chromosome 19 at 41,130,471 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0939 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039078-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.