Strain Name:
C57BL/6J-MtgxR0945Btlr/Mmmh
Stock Number:
039084-MU
Citation ID:
RRID:MMRRC_039084-MU
Other Names:
R0945 (G1), C57BL/6J-MtgxR0945Btlr
Major Collection:

Gene Information

Dnm2
Name: dynamin 2
Synonyms: Dyn2, b2b2159Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13430
HGNC: HGNC:2974
Homologene: 90883
Il4i1
Name: interleukin 4 induced 1
Synonyms: H-46, H-4, H4, Fig1, Fig1-ps, H46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14204
Homologene: 22567
Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Uri1
Name: URI1, prefoldin-like chaperone
Synonyms: Rmp, NNX3, C80913
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 19777
Homologene: 2813
Arfgef2
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99371
Homologene: 111880
Ppcdc
Name: phosphopantothenoylcysteine decarboxylase
Synonyms: 8430432M10Rik, 1810057I13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66812
VEGA: 9
Homologene: 11049
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: C630029C19Rik, nur14, NaCh6, med, seal, motor end-plate disease, nmf2, mnd-2, mnd2, NMF335, ataxia 3, nmf335, Nav1.6, nmf58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20273
Homologene: 7927
Lrsam1
Name: leucine rich repeat and sterile alpha motif containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227738
Homologene: 44526
Pdxdc1
Name: pyridoxal-dependent decarboxylase domain containing 1
Synonyms: 2210010A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 94184
Homologene: 22858
Rfc1
Name: replication factor C (activator 1) 1
Synonyms: Alp145, 140kDa, RFC140, Recc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19687
HGNC: HGNC:9969
Homologene: 2187
Exoc5
Name: exocyst complex component 5
Synonyms: SEC10, Sec10l1, PRO1912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105504
Homologene: 38195
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109151
Homologene: 11844
Miga1
Name: mitoguardin 1
Synonyms: Fam73a, Mita1, C030011O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 215708
Homologene: 18369
Chaf1a
Name: chromatin assembly factor 1, subunit A (p150)
Synonyms: CAF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27221
VEGA: 17
HGNC: HGNC:1910
Homologene: 4003
Slf1
Name: SMC5-SMC6 complex localization factor 1
Synonyms: 2700017A04Rik, Ankrd32, Brctd1, C730024G01Rik, Brctx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105377
Homologene: 13000
Il15ra
Name: interleukin 15 receptor, alpha chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16169
HGNC: HGNC:5978
Homologene: 1650
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 22767
Homologene: 56456
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226652
Homologene: 18766
Nell1
Name: NEL-like 1
Synonyms: B230343H07Rik, l7R6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 338352
HGNC: HGNC:7750
Homologene: 4486
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: Ugcgl, Epcs21, GlcT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22234
Homologene: 37763
Zfp941
Name: zinc finger protein 941
Synonyms: BC066028
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 407812
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235505
Homologene: 25183
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Zfp329
Name: zinc finger protein 329
Synonyms: 4632409L22Rik, 2810439M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67230
Homologene: 23459
Pex3
Name: peroxisomal biogenesis factor 3
Synonyms: 1700014F15Rik, 2810027F19Rik, 2900010N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56535
HGNC: HGNC:8858
Homologene: 2691
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 268527
Homologene: 8780
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: M-type receptor, Pla2g1br, PLA2-I receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Rbak
Name: RB-associated KRAB zinc finger
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 57782
Homologene: 23287
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Myrfl
Name: myelin regulatory factor-like
Synonyms: Gm239, LOC237558
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237558
VEGA: 10
Homologene: 88588
Synj1
Name: synaptojanin 1
Synonyms: A930006D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 104015
Homologene: 48252
Usp31
Name: ubiquitin specific peptidase 31
Synonyms: 6330567E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76179
Homologene: 44504
Gm6821
Name: predicted gene 6821
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 101055651
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: 1600029H12Rik, Psg30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73250
Homologene: 115938
Cnr2
Name: cannabinoid receptor 2 (macrophage)
Synonyms: cannabinoid receptor 2 (spleen), CB2-R, CB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12802
HGNC: HGNC:2160
Homologene: 1389
Olfr654
Name: olfactory receptor 654
Synonyms: GA_x6K02T2PBJ9-7215221-7216195, MOR38-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258377
Homologene: 90859
Anxa10
Name: annexin A10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 26359
HGNC: HGNC:534
Homologene: 21409
Apoa2
Name: apolipoprotein A-II
Synonyms: Alp-2, Hdl-1, ApoA-II, Apoa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11807
HGNC: HGNC:601
Homologene: 1242
Olfr1234
Name: olfactory receptor 1234
Synonyms: GA_x6K02T2Q125-50805620-50804676, MOR231-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258975
Homologene: 128156
Eid1
Name: EP300 interacting inhibitor of differentiation 1
Synonyms: EID-1, 2610002K20Rik, ORF12, Cri1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58521
HGNC: HGNC:1191
Homologene: 49376
Tmem59
Name: transmembrane protein 59
Synonyms: 3110046P06Rik, 1110001M20Rik, D4Ertd20e, MTDCF1, thymic dendritic cell-derived factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56374
HGNC: HGNC:1239
Homologene: 3583
Rpl13
Name: ribosomal protein L13
Synonyms: L13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270106
Homologene: 5568
Allc
Name: allantoicase
Synonyms: 1700012B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 94041
Homologene: 6202
Olfr112
Name: olfactory receptor 112
Synonyms: 4930580F03Rik, GA_x6K02T2PSCP-2023769-2022807, MOR218-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258096
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 34,271,419 bp
  • A to G, chromosome 1 at 171,225,699 bp
  • G to T, chromosome 1 at 171,403,286 bp
  • T to A, chromosome 2 at 11,718,327 bp
  • T to C, chromosome 2 at 32,947,909 bp
  • A to C, chromosome 2 at 60,458,410 bp
  • T to C, chromosome 2 at 89,363,255 bp
  • A to G, chromosome 2 at 125,673,577 bp
  • T to C, chromosome 2 at 166,826,969 bp
  • A to G, chromosome 3 at 88,381,046 bp
  • A to T, chromosome 3 at 152,317,663 bp
  • C to T, chromosome 4 at 59,207,798 bp
  • T to A, chromosome 4 at 107,187,725 bp
  • A to T, chromosome 4 at 135,917,321 bp
  • A to G, chromosome 5 at 65,278,709 bp
  • A to T, chromosome 5 at 143,173,579 bp
  • T to A, chromosome 7 at 12,811,468 bp
  • T to A, chromosome 7 at 17,747,344 bp
  • A to T, chromosome 7 at 37,969,678 bp
  • G to A, chromosome 7 at 44,839,704 bp
  • A to G, chromosome 7 at 50,219,585 bp
  • T to A, chromosome 7 at 104,588,672 bp
  • T to C, chromosome 7 at 121,670,253 bp
  • C to T, chromosome 7 at 140,811,664 bp
  • A to G, chromosome 8 at 62,060,245 bp
  • A to G, chromosome 8 at 90,933,002 bp
  • C to T, chromosome 8 at 123,105,174 bp
  • C to A, chromosome 9 at 21,505,660 bp
  • C to T, chromosome 9 at 57,420,158 bp
  • T to A, chromosome 9 at 78,688,941 bp
  • C to A, chromosome 10 at 13,542,676 bp
  • C to T, chromosome 10 at 116,803,394 bp
  • T to C, chromosome 12 at 16,673,802 bp
  • A to G, chromosome 12 at 28,559,963 bp
  • C to T, chromosome 13 at 40,208,829 bp
  • A to G, chromosome 13 at 77,103,471 bp
  • A to G, chromosome 14 at 49,039,342 bp
  • A to G, chromosome 15 at 101,015,787 bp
  • A to G, chromosome 16 at 13,857,432 bp
  • A to G, chromosome 16 at 35,290,111 bp
  • A to G, chromosome 16 at 90,960,445 bp
  • G to A, chromosome 17 at 37,563,387 bp
  • A to G, chromosome 17 at 56,067,441 bp
  • A to G, chromosome 19 at 6,954,878 bp
  • T to C, chromosome Y at 725,983 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0945 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039084-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.