Strain Name:
C57BL/6J-MtgxR0960Btlr/Mmmh
Stock Number:
039089-MU
Citation ID:
RRID:MMRRC_039089-MU
Other Names:
R0960 (G1), C57BL/6J-MtgxR0960Btlr
Major Collection:

Gene Information

Myo10
Name: myosin X
Synonyms: myosin-X, D15Ertd600e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Sh3gl2
Name: SH3-domain GRB2-like 2
Synonyms: endophilin A1, 9530001L19Rik, Sh3d2a, EEN-B1, B930049H17Rik, endophilin I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20404
Homologene: 20652
Casp8
Name: caspase 8
Synonyms: Caspase-8, Mch5, MACH, FLICE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12370
HGNC: HGNC:1509
Homologene: 7657
Ints6
Name: integrator complex subunit 6
Synonyms: 2900075H24Rik, Ddx26, Notch2l, DICE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18130
VEGA: 14
Homologene: 8121
Clasp1
Name: CLIP associating protein 1
Synonyms: 5730583A19Rik, 1700030C23Rik, CLASP1alpha, B130045P17Rik, mCLASP1, CLASP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76707
Homologene: 41024
Ankrd13a
Name: ankyrin repeat domain 13a
Synonyms: 1100001D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68420
Homologene: 23814
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Cdk5rap2
Name: CDK5 regulatory subunit associated protein 2
Synonyms: 2900018K03Rik, an
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214444
Homologene: 49533
Leo1
Name: Leo1, Paf1/RNA polymerase II complex component
Synonyms: LOC235497
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235497
VEGA: 9
Homologene: 133895
Sdha
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms: SDHF, FP, SDH2, 2310034D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66945
Homologene: 3073
Hmx3
Name: H6 homeobox 3
Synonyms: Nkx5.1, Nkx5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15373
HGNC: HGNC:5019
Homologene: 40612
Aamp
Name: angio-associated migratory protein
Synonyms: Aamp-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227290
HGNC: HGNC:18
Homologene: 846
Zap70
Name: zeta-chain (TCR) associated protein kinase
Synonyms: Srk, TZK, ZAP-70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22637
Homologene: 839
Tpd52
Name: tumor protein D52
Synonyms: mD52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21985
Homologene: 38007
Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Synonyms: BUBR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12236
HGNC: HGNC:1149
Homologene: 933
Atad2b
Name: ATPase family, AAA domain containing 2B
Synonyms: 1110014E10Rik, D530031C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320817
VEGA: 12
Homologene: 86351
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 142980
Homologene: 20696
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75050
VEGA: 13
Homologene: 69235
Txndc11
Name: thioredoxin domain containing 11
Synonyms: 2810408E11Rik, Txdc11, EFP1, EF-hand binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106200
Homologene: 9301
Gm4884
Name: predicted gene 4884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233164
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040766
Homologene: 85300
Tbc1d17
Name: TBC1 domain family, member 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233204
Homologene: 11656
Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms: merg1b, ERG1, M-erg, Lqt2, ether a go-go related, merg1a, LQT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16511
HGNC: HGNC:6251
Homologene: 201
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap-1, Mtap1, 6330416M19Rik, Mtap1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Pde1a
Name: phosphodiesterase 1A, calmodulin-dependent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18573
HGNC: HGNC:8774
Homologene: 21043
Flnc
Name: filamin C, gamma
Synonyms: 1110055E19Rik, actin binding protein 280, Fln2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Il12b
Name: interleukin 12b
Synonyms: Il-12b, Il-12p40, IL-12 p40, IL-23 subunit p40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16160
HGNC: HGNC:5970
Homologene: 1648
Adam26a
Name: a disintegrin and metallopeptidase domain 26A (testase 3)
Synonyms: Adam26, Dtgn4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13525
Homologene: 128363
Svopl
Name: SV2 related protein homolog (rat)-like
Synonyms: 9430071P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320590
Homologene: 52168
Vmn1r13
Name: vomeronasal 1 receptor 13
Synonyms: V1rc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113862
Homologene: 74368
Nudcd1
Name: NudC domain containing 1
Synonyms: 4921532K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67429
VEGA: 15
Homologene: 12128
Kif28
Name: kinesin family member 28
Synonyms: Gm1305, LOC383592
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 383592
Homologene: 130945
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74918
Homologene: 49784
Tspoap1
Name: TSPO associated protein 1
Synonyms: Bzrap1, peripheral
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207777
Homologene: 37961
Olfr1129
Name: olfactory receptor 1129
Synonyms: MOR264-23, GA_x6K02T2Q125-49078087-49079031, MOR264-9P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258111
Homologene: 133705
Tmem25
Name: transmembrane protein 25
Synonyms: 0610039J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71687
Homologene: 12403
Mpp2
Name: membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
Synonyms: D11Bwg0652e, Pals4, Dlg2, Dlgh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50997
HGNC: HGNC:7220
Homologene: 3920
Cntn6
Name: contactin 6
Synonyms: NB-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53870
HGNC: HGNC:2176
Homologene: 8702
Asic5
Name: acid-sensing (proton-gated) ion channel family member 5
Synonyms: Accn5, BLINaC, brain-liver-intestine amiloride-sensitive sodium channel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 58170
Homologene: 41171
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243944
Homologene: 77912
4930474N05Rik
Name: RIKEN cDNA 4930474N05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218921
Homologene: 138428
Hsf2bp
Name: heat shock transcription factor 2 binding protein
Synonyms: 4932437G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74377
HGNC: HGNC:5226
Homologene: 38263
Olfr1369-ps1
Name: olfactory receptor 1369, pseudogene 1
Synonyms: GA_x6K02T2QHY8-12126170-12125935, MOR256-31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 404504
HGNC: HGNC:8281
Selenoo
Name: selenoprotein O
Synonyms: 1300018J18Rik, Selo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223776
Homologene: 69439
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71765
VEGA: 17
Homologene: 14290
1810009A15Rik
Name: RIKEN cDNA 1810009A15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66276
Homologene: 84408
Lpcat2
Name: lysophosphatidylcholine acyltransferase 2
Synonyms: Aytl1a, LPCAT2, Aytl1, lysoPAFAT/LPCAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270084
Homologene: 41201
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 36,779,173 bp
  • T to C, chromosome 1 at 58,829,013 bp
  • T to C, chromosome 1 at 74,281,145 bp
  • C to A, chromosome 1 at 88,242,420 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • T to C, chromosome 1 at 118,552,026 bp
  • G to A, chromosome 1 at 179,695,805 bp
  • A to G, chromosome 2 at 52,212,983 bp
  • G to A, chromosome 2 at 79,865,034 bp
  • T to C, chromosome 2 at 87,575,935 bp
  • A to G, chromosome 2 at 118,606,680 bp
  • A to G, chromosome 2 at 121,301,643 bp
  • A to T, chromosome 3 at 8,943,590 bp
  • A to G, chromosome 3 at 82,006,540 bp
  • A to G, chromosome 4 at 70,243,508 bp
  • A to T, chromosome 4 at 85,377,480 bp
  • C to T, chromosome 5 at 24,322,672 bp
  • G to A, chromosome 5 at 114,786,807 bp
  • A to G, chromosome 6 at 29,441,512 bp
  • G to T, chromosome 6 at 38,017,057 bp
  • A to G, chromosome 6 at 57,210,011 bp
  • A to G, chromosome 6 at 104,774,480 bp
  • A to T, chromosome 7 at 40,993,056 bp
  • T to A, chromosome 7 at 41,042,808 bp
  • C to T, chromosome 7 at 44,848,428 bp
  • T to C, chromosome 7 at 131,543,314 bp
  • A to T, chromosome 8 at 43,568,763 bp
  • A to C, chromosome 8 at 45,397,415 bp
  • C to T, chromosome 8 at 92,869,710 bp
  • T to A, chromosome 9 at 44,795,512 bp
  • G to A, chromosome 9 at 75,445,240 bp
  • G to T, chromosome 11 at 44,408,488 bp
  • A to T, chromosome 11 at 87,770,595 bp
  • C to T, chromosome 11 at 97,664,946 bp
  • A to G, chromosome 11 at 102,061,585 bp
  • G to A, chromosome 12 at 5,006,593 bp
  • A to C, chromosome 13 at 21,116,265 bp
  • T to C, chromosome 13 at 58,323,967 bp
  • A to T, chromosome 13 at 74,323,184 bp
  • C to A, chromosome 14 at 36,096,410 bp
  • T to C, chromosome 14 at 62,709,566 bp
  • A to G, chromosome 15 at 25,801,189 bp
  • G to T, chromosome 15 at 44,427,651 bp
  • T to G, chromosome 15 at 89,096,754 bp
  • A to T, chromosome 16 at 11,091,589 bp
  • C to T, chromosome 17 at 32,007,769 bp
  • T to C, chromosome 17 at 46,676,518 bp
  • T to C, chromosome 19 at 8,890,428 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0960 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039089-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.