Strain Name:
C57BL/6J-MtgxR1029Btlr/Mmmh
Stock Number:
039131-MU
Citation ID:
RRID:MMRRC_039131-MU
Other Names:
R1029 (G1), C57BL/6J-MtgxR1029Btlr
Major Collection:

Gene Information

Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Synonyms: Her4, ErbB4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13869
HGNC: HGNC:3432
Homologene: 21084
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DOXNPH, DNAPDcs, DNA-PK, slip, dxnph, XRCC7, DNA-PKcs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Dock9
Name: dedicator of cytokinesis 9
Synonyms: B230309H04Rik, Zizimin1, D14Wsu89e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105445
Homologene: 41026
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194401
Homologene: 85288
Znrf1
Name: zinc and ring finger 1
Synonyms: Rnf42, Zrfp1, B830022L21Rik, nin283
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170737
Homologene: 41858
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233824
Homologene: 33431
Atg2b
Name: autophagy related 2B
Synonyms: 2410024A21Rik, C630028L02Rik, C030004M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76559
VEGA: 12
Homologene: 9974
Rab7
Name: RAB7, member RAS oncogene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19349
HGNC: HGNC:9788
Homologene: 3408
Zfp335
Name: zinc finger protein 335
Synonyms: 1810045J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329559
Homologene: 11129
Hspa13
Name: heat shock protein 70 family, member 13
Synonyms: Stch, 1600002I10Rik, B230217N24Rik, 60kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 110920
Homologene: 5062
Trim55
Name: tripartite motif-containing 55
Synonyms: Murf2, D830041C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381485
Homologene: 13205
Sppl2a
Name: signal peptide peptidase like 2A
Synonyms: C130089K23Rik, 2010106G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66552
Homologene: 36411
Slc35e1
Name: solute carrier family 35, member E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270066
Homologene: 49075
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: mdig, Megf7, 6430526J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212392
Homologene: 17668
Myoz1
Name: myozenin 1
Synonyms: calsarcin-2, FATZ, 2310001N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 59011
VEGA: 14
Homologene: 23311
Gfra3
Name: glial cell line derived neurotrophic factor family receptor alpha 3
Synonyms: GFR alpha-3, GFRalpha3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14587
VEGA: 18
HGNC: HGNC:4245
Homologene: 1146
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70950
VEGA: 18
Homologene: 12373
Tgs1
Name: trimethylguanosine synthase 1
Synonyms: Ncoa6ip, Pimt, D4Ertd800e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 116940
Homologene: 32608
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Gm10295
Name: predicted gene 10295
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
4930505A04Rik
Name: RIKEN cDNA 4930505A04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75087
Homologene: 18988
Taar7a
Name: trace amine-associated receptor 7A
Synonyms: LOC215856, Taar7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215856
Homologene: 110833
Fam170a
Name: family with sequence similarity 170, member A
Synonyms: Znfd, LOC225497
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225497
VEGA: 18
Homologene: 86702
Tmem117
Name: transmembrane protein 117
Synonyms: B930062P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320709
VEGA: 15
Homologene: 12992
Pak3
Name: p21 (RAC1) activated kinase 3
Synonyms: PAK-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 18481
HGNC: HGNC:8592
Homologene: 55664
Ehd3
Name: EH-domain containing 3
Synonyms: Ehd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57440
HGNC: HGNC:3244
Homologene: 81837
Vmn2r67
Name: vomeronasal 2, receptor 67
Synonyms: EG620672
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 620672
Homologene: 115466
Olfr521
Name: olfactory receptor 521
Synonyms: GA_x6K02T2PBJ9-2443810-2444775, MOR101-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258353
Homologene: 128108
Lrfn3
Name: leucine rich repeat and fibronectin type III domain containing 3
Synonyms: A530045B06Rik, SALM4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233067
Homologene: 11558
Ugt2b34
Name: UDP glucuronosyltransferase 2 family, polypeptide B34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100727
Homologene: 117389
AC242409.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100101919
Homologene: 41287
Gm10553
Name: predicted gene 10553
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Pttg1ip2
Name: PTTG1IP family member 2
Synonyms: LOC381716, 1700015F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381716
Homologene: 136447
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 46,612,721 bp
  • A to G, chromosome 1 at 68,309,614 bp
  • T to C, chromosome 1 at 85,100,449 bp
  • A to G, chromosome 2 at 91,487,027 bp
  • A to G, chromosome 2 at 126,923,594 bp
  • C to G, chromosome 2 at 164,892,678 bp
  • A to G, chromosome 3 at 19,644,742 bp
  • T to C, chromosome 4 at 3,593,471 bp
  • C to T, chromosome 5 at 5,455,919 bp
  • G to C, chromosome 5 at 86,904,387 bp
  • A to G, chromosome 6 at 88,013,642 bp
  • T to C, chromosome 6 at 120,934,678 bp
  • G to A, chromosome 7 at 30,355,922 bp
  • A to G, chromosome 7 at 46,274,595 bp
  • A to T, chromosome 7 at 71,350,700 bp
  • G to A, chromosome 7 at 85,136,766 bp
  • A to T, chromosome 7 at 99,767,224 bp
  • C to T, chromosome 7 at 121,930,529 bp
  • T to C, chromosome 8 at 45,941,780 bp
  • T to C, chromosome 8 at 72,492,571 bp
  • T to A, chromosome 8 at 111,537,354 bp
  • T to A, chromosome 9 at 9,831,572 bp
  • A to G, chromosome 10 at 23,992,541 bp
  • A to G, chromosome 11 at 30,426,177 bp
  • A to G, chromosome 11 at 30,446,389 bp
  • A to G, chromosome 12 at 105,635,773 bp
  • T to A, chromosome 14 at 19,415,957 bp
  • A to G, chromosome 14 at 20,650,532 bp
  • T to C, chromosome 14 at 121,599,684 bp
  • C to A, chromosome 15 at 95,011,336 bp
  • A to G, chromosome 16 at 15,654,749 bp
  • A to T, chromosome 16 at 75,765,237 bp
  • T to A, chromosome 17 at 73,816,326 bp
  • T to C, chromosome 18 at 22,097,725 bp
  • T to C, chromosome 18 at 34,690,839 bp
  • T to C, chromosome 18 at 50,281,674 bp
  • TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC to TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC, chromosome X at 143,743,893 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1029 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039131-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.