Strain Name:
C57BL/6J-MtgxR1078Btlr/Mmmh
Stock Number:
039164-MU
Citation ID:
RRID:MMRRC_039164-MU
Other Names:
R1078 (G1), C57BL/6J-MtgxR1078Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21828
Homologene: 20691
Myo1e
Name: myosin IE
Synonyms: 9130023P14Rik, 2310020N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Ep400
Name: E1A binding protein p400
Synonyms: 1700020J09Rik, mDomino, p400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75560
Homologene: 38779
Gtse1
Name: G two S phase expressed protein 1
Synonyms: Gtse-1, B99
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 29870
VEGA: 15
Homologene: 8489
Kdm2b
Name: lysine (K)-specific demethylase 2B
Synonyms: Fbxl10, Jhdm1b, Cxxc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 30841
Homologene: 13069
Tcf7l2
Name: transcription factor 7 like 2, T cell specific, HMG box
Synonyms: Tcf4, Tcf-4, mTcf-4B, mTcf-4E, TCF4B, TCF4E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21416
Homologene: 7564
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 213895
Homologene: 7065
Dlgap5
Name: DLG associated protein 5
Synonyms: C86398, Dlg7, Hurp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218977
Homologene: 8840
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
Homologene: 40978
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330627
Homologene: 28044
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Lmo7
Name: LIM domain only 7
Synonyms: FBXO20, LOC380928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Ccdc187
Name: coiled-coil domain containing 187
Synonyms: 4932418E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329366
Homologene: 77630
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Tcp1
Name: t-complex protein 1
Synonyms: Cct1, Tcp-1, Ccta, p63, c-cpn, TRic, Tp63, CCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21454
Homologene: 5656
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72205
Homologene: 8125
Soat2
Name: sterol O-acyltransferase 2
Synonyms: D15Wsu97e, ACAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223920
Homologene: 68355
Ell2
Name: elongation factor RNA polymerase II 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 192657
VEGA: 13
Homologene: 8094
Gfi1b
Name: growth factor independent 1B
Synonyms: Gfi-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14582
HGNC: HGNC:4238
Homologene: 31223
Zfp830
Name: zinc finger protein 830
Synonyms: Ccdc16, 2410003C20Rik, Omcg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66983
Homologene: 41655
Lrrc37a
Name: leucine rich repeat containing 37A
Synonyms: LOC237954
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237954
Homologene: 138824
Ctu2
Name: cytosolic thiouridylase subunit 2
Synonyms: 2310061F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66965
Homologene: 79815
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102075
Homologene: 18516
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329628
Homologene: 14377
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 192188
Homologene: 23022
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: A330009G12Rik, LOC381663, Sec63d1, Mer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330149
Homologene: 87103
Unc79
Name: unc-79 homolog
Synonyms: Mlca3, 9030205A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217843
Homologene: 41397
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 52020
VEGA: 17
Homologene: 45466
Pld4
Name: phospholipase D family, member 4
Synonyms: thss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104759
VEGA: 12
Homologene: 16350
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 116904
Homologene: 10813
Cyp4f13
Name: cytochrome P450, family 4, subfamily f, polypeptide 13
Synonyms: P450 CYP4F13, leukotriene B4 omega hydroxylase, 0610030I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 170716
HGNC: HGNC:2646
Homologene: 73902
Prss39
Name: protease, serine 39
Synonyms: Tesp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21755
Homologene: 84781
Myrfl
Name: myelin regulatory factor-like
Synonyms: Gm239, LOC237558
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237558
VEGA: 10
Homologene: 88588
0610010F05Rik
Name: RIKEN cDNA 0610010F05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71675
Homologene: 19038
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226438
Homologene: 130054
Tmf1
Name: TATA element modulatory factor 1
Synonyms: 7030402D04Rik, LOC232286
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232286
Homologene: 133801
Gabbr2
Name: gamma-aminobutyric acid (GABA) B receptor, 2
Synonyms: Gababr2, Gpr51, GB2, LOC242425
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Ercc4
Name: excision repair cross-complementing rodent repair deficiency, complementation group 4
Synonyms: Xpf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 50505
HGNC: HGNC:3436
Homologene: 3836
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: CDA13, ASP21, ALP56, BAE2, 1110059C24Rik, ARP1, CEAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Lrrc38
Name: leucine rich repeat containing 38
Synonyms: A230053A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242735
Homologene: 77949
Fam189a2
Name: family with sequence similarity 189, member A2
Synonyms: LOC381217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 381217
VEGA: 19
Homologene: 3540
Iltifb
Name: interleukin 10-related T cell-derived inducible factor beta
Synonyms: Il22b, IL-TIFb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 116849
Homologene: 9669
Olfr1297
Name: olfactory receptor 1297
Synonyms: MOR248-4, GA_x6K02T2Q125-72673494-72672556
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258890
Homologene: 115545
Olfr1015
Name: olfactory receptor 1015
Synonyms: MOR213-3, GA_x6K02T2Q125-47264151-47265089
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258564
Homologene: 115499
Abi3bp
Name: ABI gene family, member 3 (NESH) binding protein
Synonyms: TARSH, eratin, D930038M13Rik, 5033411B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 320712
VEGA: 16
Homologene: 134172
9130230L23Rik
Name: RIKEN cDNA 9130230L23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231253
Psme1
Name: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Synonyms: PA28a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19186
HGNC: HGNC:9568
Homologene: 4560
Hyal2
Name: hyaluronoglucosaminidase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 15587
HGNC: HGNC:5321
Homologene: 7776
Cyp2a5
Name: cytochrome P450, family 2, subfamily a, polypeptide 5
Synonyms: Coh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13087
Homologene: 85917
Olfr103
Name: olfactory receptor 103
Synonyms: GA_x6K02T2PSCP-1798423-1797482, MOR250-3, MOR250-8_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258830
Homologene: 115555
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 34,502,086 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • A to G, chromosome 1 at 135,974,847 bp
  • T to C, chromosome 2 at 26,294,377 bp
  • A to T, chromosome 2 at 28,613,865 bp
  • T to C, chromosome 2 at 85,786,093 bp
  • T to C, chromosome 2 at 111,621,345 bp
  • A to T, chromosome 2 at 180,179,764 bp
  • T to C, chromosome 3 at 38,983,086 bp
  • C to T, chromosome 4 at 46,664,833 bp
  • A to G, chromosome 4 at 143,350,518 bp
  • T to C, chromosome 5 at 65,988,355 bp
  • A to T, chromosome 5 at 106,878,830 bp
  • C to T, chromosome 5 at 110,735,522 bp
  • T to C, chromosome 5 at 122,961,541 bp
  • T to C, chromosome 6 at 97,173,300 bp
  • T to C, chromosome 6 at 118,405,221 bp
  • A to T, chromosome 7 at 19,179,762 bp
  • A to G, chromosome 7 at 26,835,541 bp
  • A to T, chromosome 7 at 81,078,600 bp
  • G to T, chromosome 7 at 109,472,319 bp
  • T to A, chromosome 8 at 105,381,677 bp
  • T to C, chromosome 8 at 122,481,499 bp
  • T to C, chromosome 9 at 70,383,999 bp
  • T to A, chromosome 9 at 107,572,246 bp
  • T to G, chromosome 10 at 12,455,566 bp
  • C to T, chromosome 10 at 86,907,133 bp
  • T to C, chromosome 10 at 116,776,732 bp
  • T to G, chromosome 10 at 118,290,151 bp
  • C to A, chromosome 11 at 23,433,175 bp
  • A to C, chromosome 11 at 23,611,762 bp
  • T to C, chromosome 11 at 82,765,339 bp
  • G to T, chromosome 11 at 103,497,631 bp
  • T to G, chromosome 12 at 103,074,853 bp
  • A to T, chromosome 12 at 112,763,442 bp
  • C to T, chromosome 13 at 38,183,106 bp
  • T to C, chromosome 13 at 75,746,419 bp
  • G to A, chromosome 13 at 92,762,926 bp
  • G to A, chromosome 14 at 47,399,566 bp
  • G to T, chromosome 14 at 55,580,650 bp
  • C to T, chromosome 14 at 101,920,474 bp
  • C to T, chromosome 15 at 85,862,307 bp
  • T to A, chromosome 15 at 102,153,138 bp
  • C to A, chromosome 16 at 13,130,197 bp
  • T to C, chromosome 16 at 56,654,081 bp
  • C to T, chromosome 16 at 97,356,860 bp
  • T to C, chromosome 17 at 12,923,204 bp
  • T to C, chromosome 17 at 30,959,373 bp
  • T to C, chromosome 17 at 32,925,568 bp
  • T to A, chromosome 17 at 37,337,026 bp
  • T to A, chromosome 19 at 23,973,575 bp
  • A to G, chromosome 19 at 55,743,195 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1078 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039164-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.