Strain Name:
C57BL/6J-MtgxR1160Btlr/Mmmh
Stock Number:
039233-MU
Citation ID:
RRID:MMRRC_039233-MU
Other Names:
R1160 (G1), C57BL/6J-MtgxR1160Btlr
Major Collection:

Gene Information

Tal1
Name: T cell acute lymphocytic leukemia 1
Synonyms: SCL/tal-1, Hpt, bHLHa17, Scl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21349
Homologene: 2400
Khdc4
Name: KH domain containing 4, pre-mRNA splicing factor
Synonyms: 2810403A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74200
Homologene: 41761
Agap1
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Synonyms: Ggap1, Centg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 347722
Homologene: 56689
Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Synonyms: MommeD2, Dnmt1o, MTase, Cxxc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Pdia3
Name: protein disulfide isomerase associated 3
Synonyms: PDI, ERp61, Erp, Plca, PDI-Q2, ERp57, ERp60, Grp58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14827
HGNC: HGNC:4606
Homologene: 68454
Srpk1
Name: serine/arginine-rich protein specific kinase 1
Synonyms: SR protein-specific kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20815
Homologene: 110962
Arl5b
Name: ADP-ribosylation factor-like 5B
Synonyms: 4930587A11Rik, Arl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75869
Homologene: 101695
Ccar2
Name: cell cycle activator and apoptosis regulator 2
Synonyms: Dbc1, 2610301G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219158
VEGA: 14
Homologene: 10910
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: CIF150, TAFII150, TAF2B, 150kDa, 4732460C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Snupn
Name: snurportin 1
Synonyms: 0610031A09Rik, Rnut1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66069
Homologene: 4166
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: 2810487N22Rik, 4632407J06Rik, B130055D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: Zak, MLTKalpha, B230120H23Rik, MLTKbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65964
Homologene: 32331
Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Synonyms: DEP-1, RPTPJ, Byp, Scc1, CD148, Scc-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: 2310001H13Rik, hyrt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67095
Homologene: 25103
Syt13
Name: synaptotagmin XIII
Synonyms: 5730409J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 80976
Homologene: 10823
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Scamp3
Name: secretory carrier membrane protein 3
Synonyms: Sc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 24045
Homologene: 4164
Bach1
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: 6230421P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12013
HGNC: HGNC:935
Homologene: 916
Tbl2
Name: transducin (beta)-like 2
Synonyms: WS-bTRP, C76179
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 27368
Homologene: 8260
Ddx17
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
Synonyms: 2610007K22Rik, p72, LOC381024, A430025E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67040
VEGA: 15
HGNC: HGNC:2740
Homologene: 101101
Trappc6b
Name: trafficking protein particle complex 6B
Synonyms: 5830498C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 78232
VEGA: 12
Homologene: 42466
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Zp2
Name: zona pellucida glycoprotein 2
Synonyms: Zp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22787
Homologene: 48194
Zmiz1
Name: zinc finger, MIZ-type containing 1
Synonyms: Zimp10, Rai17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328365
Homologene: 10667
Sox17
Name: SRY (sex determining region Y)-box 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20671
Homologene: 7948
Usf3
Name: upstream transcription factor family member 3
Synonyms: Gm608, LOC385650, LOC207806, 5530400K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: Cchl1a1, (alpha)1 subunit, D930026N18Rik, Cav1.2, L-type Cav1.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
4930432E11Rik
Name: RIKEN cDNA 4930432E11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243900
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: D230004J03Rik, B430006D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194388
Homologene: 35360
Epha3
Name: Eph receptor A3
Synonyms: Cek4, Hek4, End3, Mek4, Tyro4, Hek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13837
VEGA: 16
HGNC: HGNC:3387
Homologene: 21083
Cldnd1
Name: claudin domain containing 1
Synonyms: 1110019C08Rik, Cldn25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224250
HGNC: HGNC:1322
Homologene: 10534
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: myomaxin, 2310003D02Rik, Cmya3, 2310008C07Rik, mXin beta, A530024P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: beta3B, Naptb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: Arhgap13, 4930572H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 117600
Homologene: 56898
Slc5a4a
Name: solute carrier family 5, member 4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64452
VEGA: 10
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234214
Homologene: 83295
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225898
VEGA: 19
Homologene: 27044
Klhl5
Name: kelch-like 5
Synonyms: 1300013C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71778
HGNC: HGNC:6356
Homologene: 56736
Parp14
Name: poly (ADP-ribose) polymerase family, member 14
Synonyms: 1600029O10Rik, collaborator of Stat6, CoaSt6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 547253
Homologene: 19697
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Gtpbp10
Name: GTP-binding protein 10 (putative)
Synonyms: 4930545J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207704
Homologene: 8114
Slc19a3
Name: solute carrier family 19, member 3
Synonyms: ThTr2, A230084E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 80721
Homologene: 23530
Lrif1
Name: ligand dependent nuclear receptor interacting factor 1
Synonyms: 2010012G17Rik, 4933421E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 321000
Homologene: 10160
Mrps15
Name: mitochondrial ribosomal protein S15
Synonyms: 1500003E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66407
Homologene: 32636
Dcpp1
Name: demilune cell and parotid protein 1
Synonyms: p20, Dcpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13184
VEGA: 17
Homologene: 103921
Sccpdh
Name: saccharopine dehydrogenase (putative)
Synonyms: C330023F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109232
Homologene: 9334
Tmem132a
Name: transmembrane protein 132A
Synonyms: 6720481D13Rik, Hspa5bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 98170
Homologene: 75076
Rasd1
Name: RAS, dexamethasone-induced 1
Synonyms: Dexras1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19416
Homologene: 7509
Zfp810
Name: zinc finger protein 810
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235050
VEGA: 9
Homologene: 138299
Pglyrp4
Name: peptidoglycan recognition protein 4
Synonyms: LOC384997, LOC242097
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 384997
Homologene: 130057
Klrg2
Name: killer cell lectin-like receptor subfamily G, member 2
Synonyms: 2310020F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74253
Homologene: 52362
Olfr625-ps1
Name: olfactory receptor 625, pseudogene 1
Synonyms: GA_x6K02T2PBJ9-6416276-6417237, MOR31-15P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258169
Dcaf5
Name: DDB1 and CUL4 associated factor 5
Synonyms: BCRP2, Wdr22, BCRG2, 9430020B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320808
VEGA: 12
Homologene: 18564
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 4,491,852 bp
  • A to C, chromosome 1 at 83,022,692 bp
  • G to T, chromosome 1 at 89,843,154 bp
  • T to C, chromosome 1 at 158,600,365 bp
  • T to G, chromosome 1 at 179,684,210 bp
  • T to C, chromosome 2 at 15,069,837 bp
  • T to C, chromosome 2 at 67,509,887 bp
  • A to G, chromosome 2 at 72,441,520 bp
  • A to G, chromosome 2 at 90,444,524 bp
  • T to A, chromosome 2 at 92,943,042 bp
  • G to A, chromosome 2 at 121,432,377 bp
  • C to A, chromosome 3 at 88,708,862 bp
  • T to C, chromosome 3 at 89,181,198 bp
  • T to A, chromosome 3 at 90,728,831 bp
  • A to G, chromosome 3 at 106,732,717 bp
  • A to T, chromosome 4 at 115,068,616 bp
  • G to C, chromosome 4 at 126,047,483 bp
  • A to T, chromosome 5 at 5,554,816 bp
  • A to G, chromosome 5 at 65,141,340 bp
  • A to G, chromosome 5 at 110,295,253 bp
  • A to G, chromosome 5 at 135,159,392 bp
  • C to T, chromosome 6 at 38,629,923 bp
  • A to G, chromosome 6 at 83,404,452 bp
  • C to T, chromosome 6 at 118,612,625 bp
  • A to G, chromosome 7 at 29,562,725 bp
  • A to T, chromosome 7 at 81,466,169 bp
  • A to G, chromosome 7 at 103,682,861 bp
  • A to T, chromosome 7 at 120,136,045 bp
  • A to T, chromosome 7 at 141,801,088 bp
  • A to G, chromosome 8 at 45,770,576 bp
  • T to C, chromosome 9 at 20,918,327 bp
  • T to C, chromosome 9 at 22,278,532 bp
  • T to C, chromosome 9 at 27,051,608 bp
  • T to G, chromosome 9 at 56,957,105 bp
  • T to C, chromosome 9 at 121,392,007 bp
  • G to A, chromosome 10 at 76,178,161 bp
  • T to A, chromosome 10 at 121,855,477 bp
  • T to A, chromosome 11 at 59,964,721 bp
  • G to A, chromosome 12 at 59,050,278 bp
  • T to C, chromosome 12 at 80,340,215 bp
  • T to A, chromosome 14 at 25,654,512 bp
  • C to T, chromosome 14 at 70,139,769 bp
  • A to G, chromosome 15 at 55,071,397 bp
  • T to A, chromosome 15 at 79,541,087 bp
  • G to A, chromosome 16 at 35,856,760 bp
  • T to A, chromosome 16 at 44,218,547 bp
  • C to A, chromosome 16 at 58,731,299 bp
  • T to G, chromosome 16 at 63,773,068 bp
  • T to C, chromosome 16 at 87,715,434 bp
  • T to A, chromosome 17 at 23,881,431 bp
  • C to T, chromosome 17 at 25,246,098 bp
  • C to A, chromosome 17 at 28,599,774 bp
  • C to T, chromosome 18 at 24,985,236 bp
  • A to G, chromosome 19 at 8,933,250 bp
  • A to G, chromosome 19 at 10,858,574 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1160 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039233-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.