Strain Name:
C57BL/6J-MtgxR1271Btlr/Mmmh
Stock Number:
039337-MU
Citation ID:
RRID:MMRRC_039337-MU
Other Names:
R1271 (G1), C57BL/6J-MtgxR1271Btlr
Major Collection:

Strain Information

Foxp4
Name: forkhead box P4
Synonyms: 1200010K03Rik, 2310007G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74123
Homologene: 12536
Gabrg1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
Synonyms: GabaA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14405
HGNC: HGNC:4086
Homologene: 22570
Tnfsf4
Name: tumor necrosis factor (ligand) superfamily, member 4
Synonyms: OX40L, gp34, Txgp1l, Ath-1, TXGP1, CD134L, Ath1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22164
Homologene: 2495
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: 3110012M15Rik, Tmem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
Usp28
Name: ubiquitin specific peptidase 28
Synonyms: 9830148O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235323
VEGA: 9
Homologene: 10840
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Tent3b, Zcchc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Kpna3
Name: karyopherin (importin) alpha 3
Synonyms: IPOA4, importin alpha 4, importin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16648
VEGA: 14
HGNC: HGNC:6396
Homologene: 20520
Ccdc18
Name: coiled-coil domain containing 18
Synonyms: 1700021E15Rik, 4932411G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73254
Homologene: 35455
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Mphosph10
Name: M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Synonyms: 2810453H10Rik, 5730405D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67973
HGNC: HGNC:7213
Homologene: 134741
1700019D03Rik
Name: RIKEN cDNA 1700019D03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67080
Homologene: 49994
Kars
Name: lysyl-tRNA synthetase
Synonyms: D8Wsu108e, LysRS, D8Ertd698e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 85305
HGNC: HGNC:6215
Homologene: 4053
Gpsm1
Name: G-protein signalling modulator 1 (AGS3-like, C. elegans)
Synonyms: 1810037C22Rik, Ags3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67839
Homologene: 16987
Acadvl
Name: acyl-Coenzyme A dehydrogenase, very long chain
Synonyms: VLCAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11370
HGNC: HGNC:92
Homologene: 5
Ebf3
Name: early B cell factor 3
Synonyms: O/E-2, Olf-1/EBF-like 2, 3110018A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13593
Homologene: 56472
Magel2
Name: MAGE family member L2
Synonyms: NDNL1, Mage-l2, nM15, ns7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27385
HGNC: HGNC:6814
Homologene: 8460
Hapln3
Name: hyaluronan and proteoglycan link protein 3
Synonyms: Lpr3, 4930554N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67666
Homologene: 18654
Prkag1
Name: protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Synonyms: Prkaac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19082
VEGA: 15
HGNC: HGNC:9385
Homologene: 99712
Atad2
Name: ATPase family, AAA domain containing 2
Synonyms: 2610509G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70472
VEGA: 15
Homologene: 6044
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216742
Homologene: 28173
Shf
Name: Src homology 2 domain containing F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 435684
Homologene: 44524
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: 0710001E20Rik, LGL3, 4930565N16Rik, tomosyn 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78808
Homologene: 16402
Des
Name: desmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13346
HGNC: HGNC:2770
Homologene: 56469
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234214
Homologene: 83295
Abca14
Name: ATP-binding cassette, sub-family A (ABC1), member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67928
Homologene: 86128
Mup6
Name: major urinary protein 6
Synonyms: Gm12544
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 620807
Homologene: 74304
Mctp1
Name: multiple C2 domains, transmembrane 1
Synonyms: 2810465F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78771
Homologene: 75211
H2-M1
Name: histocompatibility 2, M region locus 1
Synonyms: H-2M1, Mb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224756
Homologene: 110792
Irf9
Name: interferon regulatory factor 9
Synonyms: p48, Irf-9, Isgf3g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16391
HGNC: HGNC:6131
Homologene: 4436
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, 4632415N18Rik, 4930463G05Rik, D19Ertd652e, Wdr96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100048534
Homologene: 36425
Or4c11
Name: olfactory receptor family 4 subfamily C member 11
Synonyms: GA_x6K02T2Q125-50339974-50340609, GA_x6K02T2Q125-50338497-50339264, MOR230-3, Olfr1207, Olfr1206
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258896
Homologene: 81567
Nsmce1
Name: NSE1 homolog, SMC5-SMC6 complex component
Synonyms: 2510027N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67711
Homologene: 41672
Tacc3
Name: transforming, acidic coiled-coil containing protein 3
Synonyms: Arnt interacting protein, Aint
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21335
Homologene: 81618
4930447C04Rik
Name: RIKEN cDNA 4930447C04 gene
Synonyms: Six6as, Six6os1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75801
Homologene: 49922
Gcm1
Name: glial cells missing homolog 1
Synonyms: glial cell deficient, glide, Gcm a, Gcm 1, Gcm1-rs1, GCMa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14531
VEGA: 9
HGNC: HGNC:4197
Homologene: 2702
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 52,925,334 bp
  • A to T, chromosome 1 at 75,360,646 bp
  • T to A, chromosome 1 at 161,395,703 bp
  • G to T, chromosome 2 at 26,344,672 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to A, chromosome 2 at 88,865,131 bp
  • G to A, chromosome 2 at 122,368,682 bp
  • A to T, chromosome 4 at 60,003,579 bp
  • T to C, chromosome 5 at 33,667,037 bp
  • T to A, chromosome 5 at 70,777,144 bp
  • A to T, chromosome 5 at 108,202,116 bp
  • T to C, chromosome 7 at 62,381,014 bp
  • A to T, chromosome 7 at 64,390,084 bp
  • T to C, chromosome 7 at 79,118,016 bp
  • T to C, chromosome 7 at 120,325,117 bp
  • T to A, chromosome 7 at 125,471,254 bp
  • C to T, chromosome 7 at 137,198,696 bp
  • T to A, chromosome 8 at 45,795,967 bp
  • C to A, chromosome 8 at 111,996,596 bp
  • G to A, chromosome 9 at 49,035,961 bp
  • A to G, chromosome 9 at 78,059,577 bp
  • A to T, chromosome 10 at 9,816,269 bp
  • T to C, chromosome 11 at 54,503,297 bp
  • A to G, chromosome 11 at 70,014,700 bp
  • A to T, chromosome 12 at 72,892,883 bp
  • A to C, chromosome 13 at 59,821,855 bp
  • A to T, chromosome 13 at 68,642,498 bp
  • T to C, chromosome 13 at 76,806,163 bp
  • A to G, chromosome 14 at 55,605,238 bp
  • G to A, chromosome 14 at 61,391,464 bp
  • T to A, chromosome 15 at 48,011,059 bp
  • T to C, chromosome 15 at 58,126,589 bp
  • C to T, chromosome 15 at 98,825,683 bp
  • T to A, chromosome 17 at 36,671,245 bp
  • G to C, chromosome 17 at 47,880,353 bp
  • T to A, chromosome 19 at 21,823,904 bp
  • C to T, chromosome 19 at 47,739,744 bp
  • G to T, chromosome 19 at 47,747,948 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1271 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039337-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.