Strain Name:
C57BL/6J-MtgxR1330Btlr/Mmmh
Stock Number:
039395-MU
Citation ID:
RRID:MMRRC_039395-MU
Other Names:
R1330 (G1), C57BL/6J-MtgxR1330Btlr
Major Collection:

Gene Information

Utp20
Name: UTP20 small subunit processome component
Synonyms: mDRIM, DRIM, 3830408P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70683
VEGA: 10
Homologene: 38373
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100710
Homologene: 41001
Osbpl1a
Name: oxysterol binding protein-like 1A
Synonyms: LOC328902, G430090F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 64291
Homologene: 84746
Wdr47
Name: WD repeat domain 47
Synonyms: 1810073M12Rik, nemitin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99512
Homologene: 8984
Rbm25
Name: RNA binding motif protein 25
Synonyms: 2610015J01Rik, A130095G20Rik, 2600011C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 67039
Lrch4
Name: leucine-rich repeats and calponin homology (CH) domain containing 4
Synonyms: 2900069C24Rik, LRRN4, LRN, 2810008P14Rik, SAP25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231798
HGNC: HGNC:6691
Homologene: 20532
Ncbp1
Name: nuclear cap binding protein subunit 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433702
HGNC: HGNC:7658
Homologene: 1859
Ddx6
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
Synonyms: mRCK/P54, HLR2, E230023J21Rik, p54, rck, 1110001P04Rik, C430015D01Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13209
VEGA: 9
HGNC: HGNC:2747
Homologene: 3238
Wap
Name: whey acidic protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22373
Homologene: 137242
Zfp318
Name: zinc finger protein 318
Synonyms: TZF, 2610034E08Rik, D530032D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57908
Homologene: 22808
Jup
Name: junction plakoglobin
Synonyms: PG, plakoglobin, gamma-catenin, D930025P04Rik, Ctnng
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16480
HGNC: HGNC:6207
Homologene: 1680
Dolk
Name: dolichol kinase
Synonyms: Tmem15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227697
Homologene: 8940
Eva1c
Name: eva-1 homolog C (C. elegans)
Synonyms: 1700092M14Rik, Fam176c, 4931408A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70967
Homologene: 14383
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: LOC381628, PGR23, Gpr113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381628
Homologene: 17826
Ncstn
Name: nicastrin
Synonyms: nicastrin, 9430068N19Rik, Nct, D1Dau13e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 59287
Homologene: 41029
Ddx41
Name: DEAD box helicase 41
Synonyms: 2900024F02Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72935
VEGA: 13
Homologene: 9431
Rfx7
Name: regulatory factor X, 7
Synonyms: 2510005N23Rik, 9930116O05Rik, D130086K05Rik, Rfxdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319758
Homologene: 11275
Pcdh12
Name: protocadherin 12
Synonyms: VE-cadherin-2, vascular endothelial cadherin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53601
HGNC: HGNC:8657
Homologene: 9574
Zfp429
Name: zinc finger protein 429
Synonyms: 2810487A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72807
Homologene: 110878
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 105242472
Rin2
Name: Ras and Rab interactor 2
Synonyms: RASSF4, 4632403N06Rik, 2010003K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74030
Homologene: 32430
Cdhr2
Name: cadherin-related family member 2
Synonyms: LOC268663, Pcdh24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 268663
Homologene: 134510
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, D17Ertd479e, FIRE, Gpr127, Emr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333315
Homologene: 35388
Kcnh7
Name: potassium voltage-gated channel, subfamily H (eag-related), member 7
Synonyms: Kv11.3, erg3, 9330137I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170738
Homologene: 13249
Dstyk
Name: dual serine/threonine and tyrosine protein kinase
Synonyms: A930019K20Rik, C430014H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213452
Homologene: 19711
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268739
Homologene: 19560
Tas1r2
Name: taste receptor, type 1, member 2
Synonyms: TR2, T1r2, Gpr71
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 83770
Homologene: 75323
Slc22a2
Name: solute carrier family 22 (organic cation transporter), member 2
Synonyms: Oct2, Orct2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20518
VEGA: 17
Homologene: 68293
Vmn1r1
Name: vomeronasal 1 receptor 1
Synonyms: Gm6628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 625823
Homologene: 83459
Vmn2r23
Name: vomeronasal 2, receptor 23
Synonyms: EG435916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435916
Homologene: 135826
Art4
Name: ADP-ribosyltransferase 4
Synonyms: 4432404K01Rik, DO, DOK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109978
HGNC: HGNC:726
Homologene: 10883
4933421I07Rik
Name: RIKEN cDNA 4933421I07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71162
Homologene: 86127
Spink11
Name: serine peptidase inhibitor, Kazal type 11
Synonyms: 9230112K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433181
Homologene: 128818
Rhod
Name: ras homolog family member D
Synonyms: Arhd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11854
HGNC: HGNC:670
Homologene: 22409
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 132,449,880 bp
  • C to T, chromosome 1 at 172,071,525 bp
  • A to T, chromosome 1 at 182,158,007 bp
  • A to T, chromosome 2 at 30,285,100 bp
  • A to G, chromosome 2 at 62,777,411 bp
  • C to T, chromosome 2 at 145,860,446 bp
  • T to C, chromosome 3 at 108,629,753 bp
  • G to A, chromosome 4 at 46,167,354 bp
  • A to G, chromosome 4 at 139,669,329 bp
  • T to A, chromosome 5 at 30,195,095 bp
  • G to A, chromosome 5 at 137,637,789 bp
  • T to A, chromosome 5 at 150,761,077 bp
  • T to C, chromosome 6 at 123,742,004 bp
  • A to T, chromosome 6 at 136,854,341 bp
  • T to C, chromosome 7 at 42,447,594 bp
  • T to A, chromosome 8 at 80,668,839 bp
  • T to C, chromosome 9 at 44,627,773 bp
  • C to T, chromosome 9 at 72,617,265 bp
  • G to A, chromosome 10 at 88,801,189 bp
  • T to C, chromosome 11 at 6,636,818 bp
  • A to T, chromosome 11 at 100,372,676 bp
  • A to G, chromosome 11 at 104,746,290 bp
  • A to G, chromosome 12 at 83,677,892 bp
  • A to G, chromosome 13 at 54,734,268 bp
  • G to A, chromosome 13 at 55,534,480 bp
  • T to C, chromosome 13 at 67,396,143 bp
  • T to C, chromosome 14 at 51,990,156 bp
  • A to C, chromosome 16 at 90,904,396 bp
  • A to C, chromosome 17 at 12,586,812 bp
  • A to G, chromosome 17 at 46,413,758 bp
  • T to A, chromosome 17 at 55,778,814 bp
  • A to G, chromosome 18 at 12,882,194 bp
  • A to G, chromosome 18 at 38,281,861 bp
  • A to G, chromosome 18 at 44,196,128 bp
  • C to A, chromosome 19 at 4,426,154 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1330 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039395-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.