Strain Name:
C57BL/6J-MtgxR1345Btlr/Mmmh
Stock Number:
039410-MU
Citation ID:
RRID:MMRRC_039410-MU
Other Names:
R1345 (G1), C57BL/6J-MtgxR1345Btlr
Major Collection:

Gene Information

Cd86
Name: CD86 antigen
Synonyms: B7-2, MB7-2, B70, Ly-58, Cd28l2, B7.2, Ly58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12524
HGNC: HGNC:1705
Homologene: 10443
Kdm5b
Name: lysine (K)-specific demethylase 5B
Synonyms: PLU-1, 2010009J12Rik, Plu1, Rb-Bp2, 2210016I17Rik, D1Ertd202e, Jarid1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75605
Homologene: 48448
Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Synonyms: MTase, Dnmt1o, Cxxc9, MommeD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Zfp7
Name: zinc finger protein 7
Synonyms: Krox-2, Zfp-7, KRAB7, Zfp65, mszf73-2, Zfp80, KRAB20, Zfp86-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223669
VEGA: 15
Homologene: 20729
Kif2a
Name: kinesin family member 2A
Synonyms: Kns2, Kif2, M-kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16563
HGNC: HGNC:6318
Homologene: 3320
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216860
Homologene: 13029
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Zfp407
Name: zinc finger protein 407
Synonyms: LOC381139, LOC240469, 6430585N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240476
Homologene: 86402
Snrpb2
Name: U2 small nuclear ribonucleoprotein B
Synonyms: 2810052G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20639
Homologene: 37728
Sucla2
Name: succinate-Coenzyme A ligase, ADP-forming, beta subunit
Synonyms: 4930547K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20916
Homologene: 2856
Mmp16
Name: matrix metallopeptidase 16
Synonyms: Membrane type 3-MMP, MT3-MMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17389
HGNC: HGNC:7162
Homologene: 55939
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: CDA-I, CDA1, 1500015A01Rik, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Fam151a
Name: family with sequence simliarity 151, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230579
Homologene: 17143
Mtm1
Name: X-linked myotubular myopathy gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 17772
HGNC: HGNC:7448
Homologene: 37279
Lzic
Name: leucine zipper and CTNNBIP1 domain containing
Synonyms: 1810030J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69151
Homologene: 12301
Usp42
Name: ubiquitin specific peptidase 42
Synonyms: 3110031A07Rik, 2410140K03Rik, D5Ertd591e, A630018G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76800
Homologene: 35425
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Akr1c18
Name: aldo-keto reductase family 1, member C18
Synonyms: 20alpha-HSD, 20alpha-hydroxysteroid dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105349
HGNC: HGNC:386
Homologene: 128661
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: LEKT1, 2310065D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 72432
Homologene: 4987
Ern2
Name: endoplasmic reticulum (ER) to nucleus signalling 2
Synonyms: Ire1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26918
Homologene: 22687
Vav1
Name: vav 1 oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22324
Homologene: 3961
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212728
Homologene: 38082
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: ALX, Hsh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209488
Homologene: 13142
Vmn2r103
Name: vomeronasal 2, receptor 103
Synonyms: EG627636
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627636
Homologene: 115024
Dll1
Name: delta like canonical Notch ligand 1
Synonyms: Delta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13388
HGNC: HGNC:2908
Homologene: 4104
Tulp2
Name: tubby-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56734
Homologene: 2492
Vmn1r170
Name: vomeronasal 1 receptor 170
Synonyms: Gm5999
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546944
Homologene: 128341
Sel1l3
Name: sel-1 suppressor of lin-12-like 3 (C. elegans)
Synonyms: 2310045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231238
Homologene: 9054
Brf1
Name: BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
Synonyms: TAF3C, TFIIIB90, GTF3B, TAFIII90, 2510002F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72308
VEGA: 12
Homologene: 1161
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 338349
Homologene: 9805
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319719
Homologene: 131217
Olfr813
Name: olfactory receptor 813
Synonyms: GA_x6K02T2PULF-11535078-11536010, MOR108-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258252
Homologene: 138308
1700001K19Rik
Name: RIKEN cDNA 1700001K19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66323
VEGA: 12
Homologene: 19832
Muc21
Name: mucin 21
Synonyms: epiglycanin, Gm9573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 672682
Rbm44
Name: RNA binding motif protein 44
Synonyms: LOC329207
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329207
Homologene: 66636
Tmem232
Name: transmembrane protein 232
Synonyms: LOC381107, E130009J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381107
VEGA: 17
Homologene: 54378
Trim43b
Name: tripartite motif-containing 43B
Synonyms: Gm8269
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 666747
Homologene: 105432
4932411G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Tedc2
Name: tubulin epsilon and delta complex 2
Synonyms: 1600002H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72016
Homologene: 45943
Vmn1r169
Name: vomeronasal 1 receptor 169
Synonyms: Gm4232
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043103
Homologene: 128341
Cypt4
Name: cysteine-rich perinuclear theca 4
Synonyms: Ckt1r2, 1700009B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235067
VEGA: 9
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 91,152,759 bp
  • A to C, chromosome 1 at 134,630,550 bp
  • T to C, chromosome 1 at 194,644,486 bp
  • A to G, chromosome 2 at 120,719,139 bp
  • T to C, chromosome 2 at 125,314,671 bp
  • A to G, chromosome 2 at 143,065,166 bp
  • A to G, chromosome 4 at 18,112,021 bp
  • A to G, chromosome 4 at 84,973,991 bp
  • A to G, chromosome 4 at 106,742,294 bp
  • A to G, chromosome 4 at 149,486,851 bp
  • G to T, chromosome 5 at 53,200,217 bp
  • A to G, chromosome 5 at 143,717,333 bp
  • A to C, chromosome 7 at 23,577,822 bp
  • C to T, chromosome 7 at 23,606,362 bp
  • C to A, chromosome 7 at 45,518,721 bp
  • A to G, chromosome 7 at 122,177,770 bp
  • G to A, chromosome 8 at 72,200,460 bp
  • T to C, chromosome 8 at 126,448,330 bp
  • G to T, chromosome 9 at 20,908,518 bp
  • A to G, chromosome 9 at 24,625,219 bp
  • G to C, chromosome 9 at 89,085,672 bp
  • A to G, chromosome 9 at 95,920,355 bp
  • A to G, chromosome 10 at 103,028,492 bp
  • T to C, chromosome 10 at 129,856,890 bp
  • A to G, chromosome 11 at 69,903,876 bp
  • C to T, chromosome 12 at 110,668,718 bp
  • A to T, chromosome 12 at 112,961,108 bp
  • T to C, chromosome 13 at 4,145,214 bp
  • A to ANNNNNNNNNNNNNNNNNNNNN, chromosome 13 at 54,525,247 bp
  • T to G, chromosome 13 at 59,726,024 bp
  • G to A, chromosome 13 at 106,993,915 bp
  • C to T, chromosome 14 at 73,560,634 bp
  • T to C, chromosome 15 at 76,890,708 bp
  • A to G, chromosome 16 at 36,618,324 bp
  • G to T, chromosome 17 at 15,373,555 bp
  • T to G, chromosome 17 at 19,794,247 bp
  • T to A, chromosome 17 at 24,216,317 bp
  • C to A, chromosome 17 at 24,216,318 bp
  • T to A, chromosome 17 at 35,621,597 bp
  • A to T, chromosome 17 at 57,301,214 bp
  • T to C, chromosome 17 at 65,450,406 bp
  • A to T, chromosome 18 at 43,990,682 bp
  • C to T, chromosome 18 at 84,559,773 bp
  • T to C, chromosome X at 71,287,231 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1345 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039410-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.