Strain Name:
C57BL/6J-MtgxR1382Btlr/Mmmh
Stock Number:
039444-MU
Citation ID:
RRID:MMRRC_039444-MU
Other Names:
R1382 (G1), C57BL/6J-MtgxR1382Btlr
Major Collection:

Gene Information

Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: Sema6D-6, Sema6D-5, Sema6D-2, Sema6D-4, Sema6D-1, 1110067B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214968
Homologene: 16195
Prkd3
Name: protein kinase D3
Synonyms: Prkcn, 4930557O20Rik, PKD3, 5730497N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75292
HGNC: HGNC:9408
Homologene: 2055
Ddc
Name: dopa decarboxylase
Synonyms: aromatic L-amino acid decarboxylase, Aadc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13195
HGNC: HGNC:2719
Homologene: 618
Dst
Name: dystonin
Synonyms: BPAG1-n, bullous pemphigoid antigen 1, bullous pemphigoid antigen 1, A830042E19Rik, athetoid, 2310001O04Rik, Bpag, nmf203, Bpag1, Macf2, nmf339, BPAG1, ah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Cuedc1
Name: CUE domain containing 1
Synonyms: C330016O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103841
Homologene: 9933
Ppp1r1a
Name: protein phosphatase 1, regulatory inhibitor subunit 1A
Synonyms: I-1, protein phosphatase inhibitor-1, inhibitor-1, 0610038N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 58200
VEGA: 15
HGNC: HGNC:9286
Homologene: 4905
Arhgef6
Name: Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Synonyms: 1700038J06Rik, 4930592P22Rik, 1600028C08Rik, alpha-PIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 73341
HGNC: HGNC:685
Homologene: 3561
Exo1
Name: exonuclease 1
Synonyms: Msa, 5730442G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26909
HGNC: HGNC:3511
Homologene: 31352
Gpi1
Name: glucose-6-phosphate isomerase 1
Synonyms: maturation factor, Gpi-1r, Gpi-1s, NK, AMF, autocrine motility factor, neuroleukin, Gpi-1, MF, Gpi-1t, NK/GPI, Org, Gpi1-t, Gpi1-s, Gpi1-r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14751
HGNC: HGNC:4458
Homologene: 145
Ago2
Name: argonaute RISC catalytic subunit 2
Synonyms: argonaute 2, 2310051F07Rik, 1110029L17Rik, Eif2c2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239528
HGNC: HGNC:3263
Homologene: 81825
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: E130014J05Rik, Ayu17-449
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214133
Homologene: 49498
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Glyr1
Name: glyoxylate reductase 1 homolog (Arabidopsis)
Synonyms: 3930401K13Rik, NDF, Npac, 2810419J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74022
VEGA: 16
Homologene: 12525
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, Dnahc7a, LOC381341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Dsg4
Name: desmoglein 4
Synonyms: lah, CDHF13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16769
Homologene: 65341
Abcf1
Name: ATP-binding cassette, sub-family F (GCN20), member 1
Synonyms: GCN20, D17Wsu166e, Abc50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224742
HGNC: HGNC:70
Homologene: 849
Cndp1
Name: carnosine dipeptidase 1 (metallopeptidase M20 family)
Synonyms: Cn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 338403
Homologene: 57178
Wdr75
Name: WD repeat domain 75
Synonyms: 1300003A18Rik, 2410118I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73674
Homologene: 32771
Ppan
Name: peter pan homolog
Synonyms: A230087P06Rik, SSF1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235036
HGNC: HGNC:9227
Homologene: 5690
Lemd3
Name: LEM domain containing 3
Synonyms: Man1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 380664
Homologene: 8633
Cep192
Name: centrosomal protein 192
Synonyms: 4631422C13Rik, D430014P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70799
VEGA: 18
Homologene: 73526
Slc5a2
Name: solute carrier family 5 (sodium/glucose cotransporter), member 2
Synonyms: Sglt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246787
Homologene: 2289
Tub
Name: tubby bipartite transcription factor
Synonyms: tub, rd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22141
Homologene: 31147
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69239
Homologene: 130756
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: PTP-BK, PTP-phi, PTP-U2, GLEPP1, PTP-oc, Ptpn15, D28, PTPROt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: 9630030F18Rik, Rpel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218194
Homologene: 33597
Mamdc2
Name: MAM domain containing 2
Synonyms: mamcan, 1200015L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71738
VEGA: 19
Homologene: 17722
Nt5dc1
Name: 5'-nucleotidase domain containing 1
Synonyms: Nt5c2l1, 6030401B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319638
Homologene: 16281
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: 6720489L24Rik, Mamdc1, Tg(Prnp-PFN1*G118V)838Kiaei, Adp, Mdga2, 9330209L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320772
Homologene: 45659
Gjb3
Name: gap junction protein, beta 3
Synonyms: D4Wsu144e, Cnx31, connexin 31, Cx31, Gjb-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14620
HGNC: HGNC:4285
Homologene: 7338
Olfr638
Name: olfactory receptor 638
Synonyms: MOR5-1, GA_x6K02T2PBJ9-6737723-6738670
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259124
Homologene: 133592
Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Synonyms: 6530401G17Rik, LOC385250, Ddef2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 211914
HGNC: HGNC:2721
Homologene: 2888
9330159F19Rik
Name: RIKEN cDNA 9330159F19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 212448
VEGA: 10
Homologene: 8804
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: 6720455I24Rik, Snep, D430044C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208777
Homologene: 14708
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Atxn7l3
Name: ataxin 7-like 3
Synonyms: E030022H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217218
Homologene: 35401
Crocc2
Name: ciliary rootlet coiled-coil, rootletin family member 2
Synonyms: E030010N08Rik, LOC381284
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381284
Homologene: 141152
Cyp4a31
Name: cytochrome P450, family 4, subfamily a, polypeptide 31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 666168
HGNC: HGNC:2642
Homologene: 128044
Adamts5
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
Synonyms: 9530092O11Rik, ADAM-TS5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 23794
VEGA: 16
HGNC: HGNC:221
Homologene: 5109
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: Psg30, 1600029H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73250
Homologene: 115938
Cope
Name: coatomer protein complex, subunit epsilon
Synonyms: Cope1, 1110005D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 59042
HGNC: HGNC:2234
Homologene: 5254
Lrrc8b
Name: leucine rich repeat containing 8 family, member B
Synonyms: 2210408K08Rik, R75581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433926
Homologene: 9103
Pate7
Name: prostate and testis expressed 7
Synonyms: Gm17727
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100312986
Homologene: 129804
Rab3gap1
Name: RAB3 GTPase activating protein subunit 1
Synonyms: 4732493F09Rik, 1700003B17Rik, p130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226407
Homologene: 45617
Prl2c2
Name: prolactin family 2, subfamily c, member 2
Synonyms: Plf1, PLF-1, Plf, MRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18811
VEGA: 13
Homologene: 40763
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 34,268,833 bp
  • A to G, chromosome 1 at 45,817,311 bp
  • A to G, chromosome 1 at 53,537,650 bp
  • C to T, chromosome 1 at 54,417,778 bp
  • G to A, chromosome 1 at 93,217,093 bp
  • G to A, chromosome 1 at 93,281,654 bp
  • A to T, chromosome 1 at 127,942,596 bp
  • A to G, chromosome 1 at 175,893,796 bp
  • C to T, chromosome 2 at 124,655,055 bp
  • C to T, chromosome 3 at 133,476,615 bp
  • G to T, chromosome 4 at 115,563,910 bp
  • G to A, chromosome 4 at 127,326,431 bp
  • A to G, chromosome 4 at 131,808,229 bp
  • A to G, chromosome 5 at 105,480,883 bp
  • T to A, chromosome 6 at 137,443,594 bp
  • T to C, chromosome 7 at 17,752,165 bp
  • T to C, chromosome 7 at 34,205,942 bp
  • G to T, chromosome 7 at 104,003,720 bp
  • G to A, chromosome 7 at 109,030,153 bp
  • G to C, chromosome 7 at 128,270,631 bp
  • A to G, chromosome 8 at 70,312,863 bp
  • A to G, chromosome 9 at 20,891,918 bp
  • T to A, chromosome 9 at 35,778,094 bp
  • A to G, chromosome 10 at 29,225,428 bp
  • C to T, chromosome 10 at 34,399,824 bp
  • A to T, chromosome 10 at 120,931,736 bp
  • T to C, chromosome 11 at 11,824,856 bp
  • C to T, chromosome 11 at 88,177,363 bp
  • C to G, chromosome 11 at 102,292,435 bp
  • A to G, chromosome 12 at 21,265,954 bp
  • A to T, chromosome 12 at 66,470,916 bp
  • G to C, chromosome 13 at 13,002,201 bp
  • T to C, chromosome 13 at 43,132,975 bp
  • C to T, chromosome 15 at 73,127,040 bp
  • A to G, chromosome 15 at 103,532,496 bp
  • GCTGCC to G, chromosome 16 at 5,021,345 bp
  • T to C, chromosome 16 at 85,870,207 bp
  • A to G, chromosome 17 at 35,963,402 bp
  • A to G, chromosome 17 at 58,974,747 bp
  • A to G, chromosome 17 at 78,957,245 bp
  • T to A, chromosome 18 at 20,465,124 bp
  • G to A, chromosome 18 at 67,856,299 bp
  • G to A, chromosome 18 at 84,634,652 bp
  • T to A, chromosome 19 at 18,853,323 bp
  • T to C, chromosome 19 at 23,333,982 bp
  • T to C, chromosome X at 57,338,562 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1382 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039444-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.