Strain Name:
C57BL/6J-MtgxR1384Btlr/Mmmh
Stock Number:
039446-MU
Citation ID:
RRID:MMRRC_039446-MU
Other Names:
R1384 (G1), C57BL/6J-MtgxR1384Btlr
Major Collection:

Gene Information

Alg10b
Name: asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
Synonyms: Deaf1, LOC380959, nse5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380959
VEGA: 15
Homologene: 6030
Tfr2
Name: transferrin receptor 2
Synonyms: Tfr2, Trfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50765
Homologene: 2428
Golga4
Name: golgi autoantigen, golgin subfamily a, 4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Rtn4
Name: reticulon 4
Synonyms: 1110020G17Rik, C130026I10Rik, NOGO, NgA, Nogo-B, Nogo-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68585
Homologene: 10743
Cpt1c
Name: carnitine palmitoyltransferase 1c
Synonyms: CPT I-C, 9630004I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78070
Homologene: 17561
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Nckap1
Name: NCK-associated protein 1
Synonyms: mh19, Hem-2, H19, Nap1, Hem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50884
HGNC: HGNC:7666
Homologene: 8384
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170935
Homologene: 15781
Pld3
Name: phospholipase D family, member 3
Synonyms: Sam-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18807
Homologene: 7893
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Fbxl18
Name: F-box and leucine-rich repeat protein 18
Synonyms: C330021B20Rik, B130019G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231863
Homologene: 41603
Upf2
Name: UPF2 regulator of nonsense transcripts homolog (yeast)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 326622
Homologene: 6101
Amph
Name: amphiphysin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218038
HGNC: HGNC:471
Homologene: 121585
Abcf3
Name: ATP-binding cassette, sub-family F (GCN20), member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27406
HGNC: HGNC:72
Homologene: 22784
Vps4a
Name: vacuolar protein sorting 4A
Synonyms: 4930589C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 116733
Homologene: 69132
Timm21
Name: translocase of inner mitochondrial membrane 21
Synonyms: 2700002I20Rik, 1700034H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67105
VEGA: 18
Homologene: 32211
Edc4
Name: enhancer of mRNA decapping 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234699
Homologene: 40937
Tspear
Name: thrombospondin type laminin G domain and EAR repeats
Synonyms: ORF65, C330046G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 252974
HGNC: HGNC:1268
Homologene: 36972
Slc45a2
Name: solute carrier family 45, member 2
Synonyms: Dbr, bls, Aim-1, Aim1, dominant brown, blanc-sale, Matp, Oca4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22293
Homologene: 9412
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Hipk1
Name: homeodomain interacting protein kinase 1
Synonyms: Myak, 1110062K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15257
Homologene: 56483
P2rx5
Name: purinergic receptor P2X, ligand-gated ion channel, 5
Synonyms: P2X5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94045
HGNC: HGNC:8536
Homologene: 1924
Prss43
Name: protease, serine 43
Synonyms: LOC272643, Tessp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 272643
Homologene: 138484
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: Cchl1a3, fmd, mdg, sj, muscle dysgenesis, Cav1.1, DHPR alpha1s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Nhsl1
Name: NHS-like 1
Synonyms: A630035H13Rik, D10Bwg0940e, 5730409E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215819
Homologene: 27834
Cyp2d41-ps
Name: cytochrome P450, family 2, subfamily d, member 41, pseudogene
Synonyms: Gm5062
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 271300
CT025680.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Igsf3
Name: immunoglobulin superfamily, member 3
Synonyms: 4833439O17Rik, 2810035F16Rik, 1700016K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 78908
HGNC: HGNC:5950
Homologene: 1182
Thap12
Name: THAP domain containing 12
Synonyms: 2900052B10Rik, Dap4, Prkrir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72981
HGNC: HGNC:9440
Homologene: 37952
Gucy1a2
Name: guanylate cyclase 1, soluble, alpha 2
Synonyms: 6330407I18Rik, A230060L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 234889
HGNC: HGNC:4684
Homologene: 47953
Ica1
Name: islet cell autoantigen 1
Synonyms: ICA69, 69kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15893
HGNC: HGNC:5343
Homologene: 7777
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Catip
Name: ciliogenesis associated TTC17 interacting protein
Synonyms: LOC241112, Gm216
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241112
Cyp2c23
Name: cytochrome P450, family 2, subfamily c, polypeptide 23
Synonyms: Cyp2c44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226143
Homologene: 115563
Strip1
Name: striatin interacting protein 1
Synonyms: 6530401O14Rik, 6330569M22Rik, Fam40a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229707
Homologene: 35064
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Nostrin
Name: nitric oxide synthase trafficker
Synonyms: mDaIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329416
Homologene: 43142
Tspyl5
Name: testis-specific protein, Y-encoded-like 5
Synonyms: E130308C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239364
VEGA: 15
Homologene: 14134
Abi3bp
Name: ABI family member 3 binding protein
Synonyms: 5033411B22Rik, D930038M13Rik, eratin, TARSH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320712
VEGA: 16
Homologene: 134172
Mrgpra2b
Name: MAS-related GPR, member A2B
Synonyms: MrgA2, Mrgpra2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 235712
Homologene: 79615
Men1
Name: multiple endocrine neoplasia 1
Synonyms: menin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17283
HGNC: HGNC:7010
Homologene: 7418
Speer4f2
Name: spermatogenesis associated glutamate (E)-rich protein 4f2
Synonyms: Gm3535, Gm3495
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100041749
Filip1l
Name: filamin A interacting protein 1-like
Synonyms: 4631422O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78749
Homologene: 37121
Tbx2
Name: T-box 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21385
Homologene: 38123
Myoz2
Name: myozenin 2
Synonyms: calsarcin-1, 1110012I24Rik, Fatz-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 59006
HGNC: HGNC:1330
Homologene: 9583
Pars2
Name: prolyl-tRNA synthetase (mitochondrial)(putative)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230577
Homologene: 5830
A930033H14Rik
Name: RIKEN cDNA A930033H14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320700
4930408O17Rik
Name: RIKEN cDNA 4930408O17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,364,363 bp
  • A to G, chromosome 1 at 136,094,971 bp
  • G to A, chromosome 2 at 5,960,989 bp
  • A to G, chromosome 2 at 69,189,062 bp
  • T to C, chromosome 2 at 76,775,658 bp
  • A to G, chromosome 2 at 80,533,670 bp
  • C to A, chromosome 2 at 120,673,636 bp
  • T to C, chromosome 3 at 101,451,296 bp
  • A to G, chromosome 3 at 103,758,774 bp
  • T to C, chromosome 3 at 107,626,839 bp
  • A to T, chromosome 3 at 123,026,116 bp
  • T to C, chromosome 4 at 106,653,716 bp
  • A to T, chromosome 5 at 17,374,449 bp
  • G to A, chromosome 5 at 110,323,664 bp
  • T to C, chromosome 5 at 137,586,820 bp
  • G to A, chromosome 5 at 142,886,223 bp
  • T to G, chromosome 5 at 143,386,096 bp
  • G to A, chromosome 6 at 8,742,262 bp
  • A to G, chromosome 7 at 27,537,657 bp
  • G to A, chromosome 7 at 44,960,924 bp
  • T to A, chromosome 7 at 46,273,695 bp
  • T to A, chromosome 7 at 47,463,994 bp
  • T to C, chromosome 7 at 98,703,438 bp
  • T to A, chromosome 8 at 105,892,382 bp
  • T to A, chromosome 8 at 107,036,644 bp
  • A to C, chromosome 9 at 3,759,620 bp
  • T to A, chromosome 9 at 39,046,904 bp
  • A to G, chromosome 9 at 110,827,442 bp
  • A to G, chromosome 9 at 118,565,651 bp
  • A to T, chromosome 10 at 18,408,513 bp
  • A to G, chromosome 10 at 69,212,361 bp
  • T to C, chromosome 10 at 77,866,332 bp
  • A to T, chromosome 11 at 29,736,437 bp
  • A to G, chromosome 11 at 73,167,890 bp
  • A to G, chromosome 11 at 85,833,492 bp
  • G to A, chromosome 12 at 104,871,192 bp
  • G to A, chromosome 13 at 19,142,028 bp
  • G to A, chromosome 15 at 6,458,934 bp
  • A to G, chromosome 15 at 11,025,746 bp
  • T to A, chromosome 15 at 33,687,380 bp
  • A to G, chromosome 15 at 34,409,810 bp
  • G to A, chromosome 15 at 82,779,517 bp
  • A to G, chromosome 15 at 90,227,582 bp
  • A to G, chromosome 16 at 17,297,537 bp
  • G to A, chromosome 16 at 20,559,303 bp
  • A to G, chromosome 16 at 56,574,499 bp
  • A to G, chromosome 16 at 57,571,289 bp
  • G to C, chromosome 18 at 84,949,262 bp
  • T to C, chromosome 19 at 6,339,891 bp
  • A to G, chromosome 19 at 44,013,663 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1384 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039446-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.