Strain Name:
C57BL/6J-MtgxR1411Btlr/Mmmh
Stock Number:
039467-MU
Citation ID:
RRID:MMRRC_039467-MU
Other Names:
R1411 (G1), C57BL/6J-MtgxR1411Btlr
Major Collection:

Gene Information

Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: b2b692Clo, SW1/SNF, b2b508.1Clo, Brg1, SNF2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20586
Homologene: 135927
Cbx5
Name: chromobox 5
Synonyms: heterochromatin protein 1 alpha, Hp1alpha, HP1, 2610029O15Rik, Hp1a, HP1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12419
HGNC: HGNC:1555
Homologene: 7257
Nup188
Name: nucleoporin 188
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227699
Homologene: 45683
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: WSTF, Wbscr9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 360013
Homologene: 7977
Cdc73
Name: cell division cycle 73, Paf1/RNA polymerase II complex component
Synonyms: Hrpt2, C130030P16Rik, 8430414L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 214498
Homologene: 11571
Wdr12
Name: WD repeat domain 12
Synonyms: Ytm1, Ytm1p, 4933402C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 57750
Homologene: 10098
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: 5830451P18Rik, Duplin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67772
Homologene: 72405
Cdcp1
Name: CUB domain containing protein 1
Synonyms: E030027H19Rik, 9030022E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 109332
Homologene: 11276
Nupl1
Name: nucleoporin like 1
Synonyms: 1700017F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71844
VEGA: 14
Homologene: 40924
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: Nrbp, B230344L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 171395
Homologene: 51376
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100604
Homologene: 12997
Abhd8
Name: abhydrolase domain containing 8
Synonyms: 0910001L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 64296
Homologene: 11188
Flywch1
Name: FLYWCH-type zinc finger 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224613
VEGA: 17
Homologene: 72130
Ercc5
Name: excision repair cross-complementing rodent repair deficiency, complementation group 5
Synonyms: Xpg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22592
HGNC: HGNC:3437
Homologene: 133551
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, b2b1000Clo, LTBP-1, Ltbp1L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Flt1
Name: FMS-like tyrosine kinase 1
Synonyms: vascular endothelial growth factor receptor-1, VEGFR-1, Flt-1, VEGFR1, sFlt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14254
HGNC: HGNC:3763
Homologene: 134179
Gpld1
Name: glycosylphosphatidylinositol specific phospholipase D1
Synonyms: 6330541J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14756
HGNC: HGNC:4459
Homologene: 1152
Cyp2j11
Name: cytochrome P450, family 2, subfamily j, polypeptide 11
Synonyms: Cyp2j11-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100066
Homologene: 133819
Tfip11
Name: tuftelin interacting protein 11
Synonyms: Tip39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54723
Homologene: 40813
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223825
VEGA: 15
Homologene: 128807
Iqcm
Name: IQ motif containing M
Synonyms: 1700007B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71831
Homologene: 53050
RP24-170A20.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Serpinb9c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9c
Synonyms: NK9, Spi11, 3830421J05Rik, ovalbumin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20707
HGNC: HGNC:8955
Srp54a
Name: signal recognition particle 54A
Synonyms: Srp54, 54K subunit of signal recognition particle, 54kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 24067
VEGA: 12
Homologene: 2362
Vmn2r108
Name: vomeronasal 2, receptor 108
Synonyms: EG627805
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627805
Homologene: 129678
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Cpeb2
Name: cytoplasmic polyadenylation element binding protein 2
Synonyms: A630055H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231207
Homologene: 17995
Tnrc18
Name: trinucleotide repeat containing 18
Synonyms: Zfp469, EG381742
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231861
Homologene: 45603
Dgkq
Name: diacylglycerol kinase, theta
Synonyms: DAGK7, Dgk theta, 110kDa, Dgkd, Dagk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 110524
HGNC: HGNC:2856
Homologene: 20352
Plxnc1
Name: plexin C1
Synonyms: vespr, CD232, 2510048K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 54712
HGNC: HGNC:9106
Homologene: 4211
Pdzrn4
Name: PDZ domain containing RING finger 4
Synonyms: SAMCAP3L, LNX4, 1110017D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239618
VEGA: 15
Homologene: 85433
Vmn1r201
Name: vomeronasal 1 receptor 201
Synonyms: V1ri4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171255
Homologene: 110880
Vmn2r117
Name: vomeronasal 2, receptor 117
Synonyms: EG619788, V2Rp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 619788
Homologene: 86604
Gm1527
Name: predicted gene 1527
Synonyms: LOC385263
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 385263
Homologene: 133976
Zfp974
Name: zinc finger protein 974
Synonyms: 1700049G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73430
Olfr986
Name: olfactory receptor 986
Synonyms: MOR104-3, GA_x6K02T2PVTD-33886895-33887833
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258608
VEGA: 9
Homologene: 105185
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: Pdi4, PAD type IV, Pad4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18602
Homologene: 7883
Gm960
Name: predicted gene 960
Synonyms: Top6bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 381196
VEGA: 19
Homologene: 69381
Vmn1r199
Name: vomeronasal 1 receptor 199
Synonyms: V1rh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171247
Homologene: 110880
Slc9a7
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 7
Synonyms: NHE7, A530087D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 236727
Homologene: 32785
Cyp2c67
Name: cytochrome P450, family 2, subfamily c, polypeptide 67
Synonyms: C730004C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 545288
Homologene: 74936
Dbx2
Name: developing brain homeobox 2
Synonyms: 9430056A22Rik, LOC383001
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223843
Homologene: 54981
Acp4
Name: acid phosphatase 4
Synonyms: EG546967, Acpt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100503991
Homologene: 57200
Frmd3
Name: FERM domain containing 3
Synonyms: 4.1O, 9430066I12Rik, EPB41L4O, P410
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242506
Homologene: 16012
Gzma
Name: granzyme A
Synonyms: Ctla-3, serine esterase 1, TSP1, BLT esterase, SE1, Hanukah factor, H factor, Hf, Ctla3, TSP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14938
VEGA: 13
HGNC: HGNC:4708
Homologene: 21237
Ac165356.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Slc25a23
Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Synonyms: SCaMC-3, 2310067G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66972
Homologene: 11467
Speer4e
Name: spermatogenesis associated glutamate (E)-rich protein 4e
Synonyms: SPEER-4E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 624245
Homologene: 69402
Il1rapl1
Name: interleukin 1 receptor accessory protein-like 1
Synonyms: OPHN4, TIGIRR-2, 6330532G10Rik, IL1R8, MRX34, IL1RAPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 331461
HGNC: HGNC:5996
Homologene: 8609
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 20,373,896 bp
  • A to G, chromosome 1 at 44,178,281 bp
  • A to T, chromosome 1 at 60,088,072 bp
  • A to G, chromosome 1 at 143,609,514 bp
  • A to G, chromosome 2 at 30,343,795 bp
  • A to G, chromosome 3 at 28,914,483 bp
  • T to C, chromosome 4 at 74,153,621 bp
  • A to G, chromosome 4 at 96,345,216 bp
  • C to T, chromosome 4 at 140,752,603 bp
  • A to C, chromosome 5 at 14,935,108 bp
  • T to A, chromosome 5 at 31,245,813 bp
  • T to G, chromosome 5 at 43,233,770 bp
  • G to A, chromosome 5 at 105,608,179 bp
  • C to A, chromosome 5 at 108,650,362 bp
  • G to T, chromosome 5 at 112,333,033 bp
  • T to C, chromosome 5 at 135,230,323 bp
  • T to C, chromosome 5 at 142,765,947 bp
  • C to T, chromosome 5 at 147,580,316 bp
  • A to G, chromosome 7 at 27,911,209 bp
  • A to G, chromosome 7 at 44,256,843 bp
  • C to T, chromosome 7 at 106,083,479 bp
  • T to A, chromosome 8 at 71,461,730 bp
  • T to A, chromosome 8 at 75,629,702 bp
  • C to A, chromosome 8 at 110,575,031 bp
  • C to A, chromosome 9 at 21,658,955 bp
  • C to T, chromosome 9 at 40,187,139 bp
  • A to T, chromosome 9 at 123,190,112 bp
  • A to T, chromosome 10 at 39,892,140 bp
  • A to T, chromosome 10 at 94,906,450 bp
  • A to G, chromosome 11 at 8,868,625 bp
  • G to C, chromosome 11 at 77,845,382 bp
  • T to C, chromosome 12 at 55,255,528 bp
  • T to C, chromosome 13 at 22,383,501 bp
  • T to C, chromosome 13 at 22,474,679 bp
  • T to A, chromosome 13 at 24,962,808 bp
  • C to G, chromosome 13 at 33,151,834 bp
  • A to G, chromosome 13 at 40,142,787 bp
  • C to T, chromosome 13 at 113,096,208 bp
  • C to T, chromosome 14 at 52,224,646 bp
  • A to T, chromosome 14 at 60,244,670 bp
  • A to C, chromosome 15 at 4,918,317 bp
  • A to G, chromosome 15 at 92,771,013 bp
  • T to C, chromosome 15 at 95,632,381 bp
  • A to T, chromosome 15 at 103,213,120 bp
  • A to T, chromosome 17 at 20,462,845 bp
  • T to C, chromosome 17 at 23,460,553 bp
  • T to C, chromosome 17 at 23,755,824 bp
  • A to G, chromosome 17 at 57,059,622 bp
  • A to G, chromosome 17 at 75,225,285 bp
  • A to G, chromosome 19 at 4,626,196 bp
  • T to A, chromosome 19 at 39,638,591 bp
  • A to G, chromosome X at 20,162,244 bp
  • T to A, chromosome X at 86,747,298 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1411 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039467-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.