Strain Name:
C57BL/6J-MtgxR1429Btlr/Mmmh
Stock Number:
039485-MU
Citation ID:
RRID:MMRRC_039485-MU
Other Names:
R1429 (G1), C57BL/6J-MtgxR1429Btlr
Major Collection:

Gene Information

Pmel
Name: premelanosome protein
Synonyms: Pmel17, Si, D10H12S53E, gp100, D12S53Eh, gp87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20431
VEGA: 10
Homologene: 5048
Ess2
Name: ess-2 splicing factor
Synonyms: Dgcr14, Es2el, Dgsi, ES2, D16H22S1269E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 27886
VEGA: 16
Homologene: 11184
Zfp423
Name: zinc finger protein 423
Synonyms: ataxia1, Roaz, Ebfaz, Zfp104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94187
Homologene: 9010
Zmym6
Name: zinc finger, MYM-type 6
Synonyms: Zfp258, D4Wsu24e, 9330177P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100177
Homologene: 5186
Ddx50
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
Synonyms: 8430408E17Rik, 4933429B04Rik, GU2, RH-II/Gubeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 94213
VEGA: 10
Homologene: 56986
Armc8
Name: armadillo repeat containing 8
Synonyms: HSPC056, Gid5, 1200015K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74125
Homologene: 9121
Wdr5
Name: WD repeat domain 5
Synonyms: Big-3, 2410008O07Rik, Bmp2-induced gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 140858
Homologene: 59931
Naa16
Name: N(alpha)-acetyltransferase 16, NatA auxiliary subunit
Synonyms: Narg1l, 1300019C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66897
Homologene: 134838
Rps24
Name: ribosomal protein S24
Synonyms: MRP S24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 20088
VEGA: 14
Homologene: 68148
Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Synonyms: 5430432H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19725
VEGA: 17
HGNC: HGNC:9983
Homologene: 30980
Rsbn1l
Name: round spermatid basic protein 1-like
Synonyms: C330002G24Rik, 8430412F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242860
Homologene: 19435
Itgb1
Name: integrin beta 1 (fibronectin receptor beta)
Synonyms: Gm9863, CD29, 4633401G24Rik, Fnrb, beta1 integrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16412
HGNC: HGNC:6153
Homologene: 22999
Fam135a
Name: family with sequence similarity 135, member A
Synonyms: 4921533L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68187
Homologene: 32665
Alg8
Name: asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
Synonyms: LOC381903
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381903
Homologene: 6931
Pgap1
Name: post-GPI attachment to proteins 1
Synonyms: PGAP1, oto, 9030223K07Rik, 5033403E17Rik, D230012E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241062
Homologene: 41605
Wscd1
Name: WSC domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216881
Homologene: 18590
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Gm5134
Name: predicted gene 5134
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 333669
Homologene: 129891
S100a16
Name: S100 calcium binding protein A16
Synonyms: 2300002L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67860
Homologene: 12201
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: myosin heavy chain 2X, IId, IId/x, Myhsf2, Myhs-f, Myhs-f2, MyHC-IId/x, A530084A17Rik, MYHC-IIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Olfr183
Name: olfactory receptor 183
Synonyms: GA_x54KRFPKG5P-55229158-55230087, MOR183-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258478
Homologene: 27178
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: Giantin, Gm6840, 6330407A06Rik, C130074L01Rik, F730017E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329421
Homologene: 51393
Dsg1b
Name: desmoglein 1 beta
Synonyms: Dsg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225256
HGNC: HGNC:3048
Homologene: 1463
Arhgef4
Name: Rho guanine nucleotide exchange factor (GEF) 4
Synonyms: Asef, C230030N03Rik, 9330140K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Fam83b
Name: family with sequence similarity 83, member B
Synonyms: C530008M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208994
Homologene: 19478
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: Dnahc7b, LOC227058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227058
Homologene: 41287
Rassf8
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Synonyms: mHoj-1, 5133400D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71323
Homologene: 5219
Cactin
Name: cactin, spliceosome C complex subunit
Synonyms: 2510012J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70312
VEGA: 10
Homologene: 69553
Fxyd3
Name: FXYD domain-containing ion transport regulator 3
Synonyms: Mat8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17178
HGNC: HGNC:4027
Homologene: 4356
Hmgxb3
Name: HMG box domain containing 3
Synonyms: 2510002C16Rik, A630042L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106894
VEGA: 18
Homologene: 44229
Cdh15
Name: cadherin 15
Synonyms: Mcad, Cdh14, M cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Cpxm1
Name: carboxypeptidase X 1 (M14 family)
Synonyms: Cpx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56264
Homologene: 10485
Phc2
Name: polyhomeotic 2
Synonyms: D4Ertd810e, D130050K19Rik, Edr2, Mph2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54383
HGNC: HGNC:3183
Homologene: 75090
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243944
Homologene: 77912
Vmn2r67
Name: vomeronasal 2, receptor 67
Synonyms: EG620672
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620672
Homologene: 115466
Stx19
Name: syntaxin 19
Synonyms: A030009B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 68159
Homologene: 55777
Tas2r105
Name: taste receptor, type 2, member 105
Synonyms: T2R05, mt2r5, mGR05, T2r5, T2R9, Tas2r5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 57252
Homologene: 69307
Gpat3
Name: glycerol-3-phosphate acyltransferase 3
Synonyms: Agpat9, 4933407I02Rik, A230097K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231510
Homologene: 13099
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 24,044,267 bp
  • A to G, chromosome 1 at 34,810,339 bp
  • G to T, chromosome 1 at 46,289,656 bp
  • T to C, chromosome 1 at 54,494,861 bp
  • A to G, chromosome 2 at 27,520,560 bp
  • A to C, chromosome 2 at 70,253,007 bp
  • A to T, chromosome 2 at 130,396,444 bp
  • A to C, chromosome 3 at 90,542,084 bp
  • T to C, chromosome 4 at 127,123,879 bp
  • C to A, chromosome 4 at 128,743,555 bp
  • A to G, chromosome 5 at 20,920,018 bp
  • G to A, chromosome 5 at 100,893,087 bp
  • T to C, chromosome 6 at 131,686,941 bp
  • G to T, chromosome 6 at 145,815,190 bp
  • T to A, chromosome 7 at 31,073,621 bp
  • A to T, chromosome 7 at 40,993,056 bp
  • T to A, chromosome 7 at 85,152,823 bp
  • C to T, chromosome 7 at 97,390,292 bp
  • T to A, chromosome 8 at 87,686,442 bp
  • G to C, chromosome 8 at 122,857,495 bp
  • T to C, chromosome 8 at 128,717,676 bp
  • G to T, chromosome 9 at 76,492,577 bp
  • A to G, chromosome 9 at 99,536,207 bp
  • G to A, chromosome 10 at 62,647,068 bp
  • T to A, chromosome 10 at 75,978,381 bp
  • T to C, chromosome 10 at 81,323,678 bp
  • T to C, chromosome 10 at 92,821,038 bp
  • G to A, chromosome 10 at 128,718,992 bp
  • C to A, chromosome 11 at 67,217,910 bp
  • T to A, chromosome 11 at 71,760,174 bp
  • A to G, chromosome 14 at 24,491,762 bp
  • A to G, chromosome 14 at 79,359,527 bp
  • G to A, chromosome 16 at 17,902,205 bp
  • A to G, chromosome 16 at 36,900,563 bp
  • G to A, chromosome 16 at 59,000,138 bp
  • G to A, chromosome 16 at 62,822,597 bp
  • G to T, chromosome 17 at 56,804,369 bp
  • A to G, chromosome 18 at 20,390,195 bp
  • C to T, chromosome 18 at 61,150,433 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1429 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039485-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.