Strain Name:
C57BL/6J-MtgxR1534Btlr/Mmmh
Stock Number:
039573-MU
Citation ID:
RRID:MMRRC_039573-MU
Other Names:
R1534 (G1), C57BL/6J-MtgxR1534Btlr
Major Collection:

Gene Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: N-CoR, Rxrip13, A230020K14Rik, 5730405M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20370
Homologene: 10948
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271639
Homologene: 10188
Frrs1
Name: ferric-chelate reductase 1
Synonyms: Sdfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20321
Homologene: 40653
Top1
Name: topoisomerase (DNA) I
Synonyms: Top-1, D130064I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21969
Homologene: 2467
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Cwc27
Name: CWC27 spliceosome-associated protein
Synonyms: NY-CO-10, 3110009E13Rik, Sdccag10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67285
Homologene: 21192
Usp28
Name: ubiquitin specific peptidase 28
Synonyms: 9830148O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235323
VEGA: 9
Homologene: 10840
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, Drf1, Dia1, D18Wsu154e, mDia1, Diap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Gan
Name: giant axonal neuropathy
Synonyms: gigaxonin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209239
HGNC: HGNC:4137
Homologene: 32523
Eif4b
Name: eukaryotic translation initiation factor 4B
Synonyms: 2310046H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75705
VEGA: 15
HGNC: HGNC:3285
Homologene: 83162
Brd1
Name: bromodomain containing 1
Synonyms: 1110059H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223770
HGNC: HGNC:1102
Homologene: 40956
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233532
Homologene: 41142
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Palm
Name: paralemmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18483
VEGA: 10
HGNC: HGNC:8594
Homologene: 1937
Zfp180
Name: zinc finger protein 180
Synonyms: D130011P11, HHZ168, 2310040I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210135
Homologene: 8306
Satb2
Name: special AT-rich sequence binding protein 2
Synonyms: BAP002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 212712
Homologene: 32249
Ankrd13c
Name: ankyrin repeat domain 13c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433667
Homologene: 41804
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: C530005A01Rik, 6030465E24Rik, spastic paraplegia 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214585
Homologene: 41614
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69116
Homologene: 10804
Uty
Name: ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Synonyms: Hydb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22290
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, Mtap2, repro4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Mtr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Synonyms: methionine synthase, MS, D830038K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238505
VEGA: 13
HGNC: HGNC:7468
Homologene: 37280
Pfkp
Name: phosphofructokinase, platelet
Synonyms: PFK-C, 1200015H23Rik, 9330125N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56421
HGNC: HGNC:8878
Homologene: 20579
Zfp142
Name: zinc finger protein 142
Synonyms: 9330177B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 77264
Homologene: 3723
Rrbp1
Name: ribosome binding protein 1
Synonyms: mRRp0, ES/130, p180, mRRp1.8, mRRp2, mRRp5.4, mRRp10, mRRp16.8, mRRp15b, mRRp15a, mRRp41, mRRp47, 5730465C04Rik, 1700087N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 81910
Homologene: 68138
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: FIC1, Ic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Cyp4f18
Name: cytochrome P450, family 4, subfamily f, polypeptide 18
Synonyms: 1810054N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72054
HGNC: HGNC:2646
Homologene: 128623
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Rexo2
Name: RNA exonuclease 2
Synonyms: 1810038D15Rik, Sfn, Smfn, Rex2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 104444
VEGA: 9
Homologene: 6447
Tspan11
Name: tetraspanin 11
Synonyms: 1110014F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68498
Homologene: 23595
Prkg2
Name: protein kinase, cGMP-dependent, type II
Synonyms: cGK-II, Prkgr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19092
HGNC: HGNC:9416
Homologene: 4556
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Wdr87-ps
Name: WD repeat domain 87, pseudogene
Synonyms: 4932431P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114675
Klra3
Name: killer cell lectin-like receptor, subfamily A, member 3
Synonyms: 5E6, Ly49C, Nk-2, Ly49c, NK-2.1, Nk2.1, Nk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16634
Homologene: 110821
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Bpifb5
Name: BPI fold containing family B, member 5
Synonyms: BC018465
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228802
Homologene: 64814
Sos2
Name: SOS Ras/Rho guanine nucleotide exchange factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20663
Homologene: 38253
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Ptprn
Name: protein tyrosine phosphatase, receptor type, N
Synonyms: IA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19275
HGNC: HGNC:9676
Homologene: 48142
Vmn2r56
Name: vomeronasal 2, receptor 56
Synonyms: EG629079
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 629079
Homologene: 104040
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Fmi1, flamingo, Adgrc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
D130040H23Rik
Name: RIKEN cDNA D130040H23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 211135
Homologene: 138403
Ankfn1
Name: ankyrin-repeat and fibronectin type III domain containing 1
Synonyms: LOC382543, 4932411E22Rik, nmf9, mWAKE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 382543
Homologene: 34996
Tlcd5
Name: TLC domain containing 5
Synonyms: LOC235300, Tmem136
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235300
VEGA: 9
Homologene: 72560
Prr14
Name: proline rich 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233895
Homologene: 11424
Lrrc18
Name: leucine rich repeat containing 18
Synonyms: mtLR1, 4930442L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67580
Homologene: 81914
Wars2
Name: tryptophanyl tRNA synthetase 2 (mitochondrial)
Synonyms: 9430020O07Rik, TrpRS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70560
Homologene: 5673
Cyp2c69
Name: cytochrome P450, family 2, subfamily c, polypeptide 69
Synonyms: AI098658
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100043108
VEGA: 19
Homologene: 74936
Hnf1b
Name: HNF1 homeobox B
Synonyms: hepatocyte nuclear factor-1 beta, vHNF1, Tcf-2, HNF-1Beta, Hnf1beta, LFB3, Tcf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21410
Homologene: 396
Trappc6a
Name: trafficking protein particle complex 6A
Synonyms: 4930519D19Rik, 1810073E21Rik, TRS33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67091
Homologene: 69370
Or5w22
Name: olfactory receptor family 5 subfamily W member 22
Synonyms: V5, Olfr4-2, GA_x6K02T2Q125-49033418-49034341, MOR177-5, Olfr153
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110511
Homologene: 128127
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
B4galt2
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53418
HGNC: HGNC:925
Homologene: 2804
Or52n2c
Name: olfactory receptor family 52 subfamily N member 2C
Synonyms: GA_x6K02T2PBJ9-7554614-7553658, MOR34-3, Olfr668
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259061
Homologene: 64947
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 56,948,233 bp
  • G to A, chromosome 1 at 66,413,180 bp
  • G to T, chromosome 1 at 74,572,088 bp
  • A to C, chromosome 1 at 75,257,943 bp
  • T to C, chromosome 1 at 165,518,312 bp
  • T to C, chromosome 2 at 27,995,695 bp
  • T to A, chromosome 2 at 87,532,672 bp
  • G to A, chromosome 2 at 122,092,325 bp
  • A to G, chromosome 2 at 143,988,313 bp
  • T to G, chromosome 2 at 154,229,499 bp
  • T to C, chromosome 2 at 160,714,232 bp
  • T to C, chromosome 3 at 38,890,089 bp
  • C to T, chromosome 3 at 99,216,861 bp
  • A to T, chromosome 3 at 116,878,408 bp
  • A to G, chromosome 3 at 158,001,120 bp
  • T to C, chromosome 4 at 117,877,472 bp
  • T to C, chromosome 4 at 139,428,151 bp
  • C to T, chromosome 4 at 156,176,684 bp
  • T to C, chromosome 5 at 98,994,561 bp
  • G to C, chromosome 6 at 127,949,805 bp
  • G to C, chromosome 6 at 130,333,144 bp
  • A to G, chromosome 7 at 12,694,027 bp
  • A to G, chromosome 7 at 19,514,213 bp
  • A to T, chromosome 7 at 24,101,523 bp
  • G to T, chromosome 7 at 29,530,429 bp
  • G to GACGGCGGCA, chromosome 7 at 97,579,909 bp
  • G to A, chromosome 7 at 104,925,414 bp
  • T to C, chromosome 7 at 105,772,040 bp
  • C to T, chromosome 7 at 127,473,982 bp
  • G to A, chromosome 8 at 41,287,701 bp
  • T to C, chromosome 8 at 69,302,726 bp
  • T to A, chromosome 8 at 71,992,955 bp
  • G to A, chromosome 8 at 117,187,429 bp
  • A to G, chromosome 9 at 43,111,628 bp
  • A to T, chromosome 9 at 48,468,890 bp
  • A to G, chromosome 9 at 48,985,506 bp
  • A to G, chromosome 9 at 108,848,884 bp
  • T to G, chromosome 10 at 79,816,903 bp
  • G to T, chromosome 11 at 62,378,504 bp
  • T to C, chromosome 11 at 73,145,605 bp
  • A to G, chromosome 11 at 77,963,045 bp
  • A to G, chromosome 11 at 83,893,583 bp
  • C to T, chromosome 11 at 89,523,151 bp
  • A to G, chromosome 12 at 69,616,955 bp
  • A to G, chromosome 13 at 6,619,538 bp
  • A to T, chromosome 13 at 12,235,544 bp
  • A to T, chromosome 13 at 104,658,015 bp
  • A to G, chromosome 14 at 33,008,521 bp
  • T to C, chromosome 15 at 88,689,663 bp
  • T to C, chromosome 15 at 102,093,728 bp
  • A to G, chromosome 16 at 5,091,948 bp
  • T to C, chromosome 16 at 35,253,259 bp
  • A to T, chromosome 16 at 89,867,508 bp
  • A to G, chromosome 18 at 37,896,093 bp
  • C to T, chromosome 18 at 64,545,264 bp
  • T to A, chromosome 19 at 39,851,149 bp
  • A to G, chromosome Y at 1,245,440 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1534 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039573-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.