Strain Name:
C57BL/6J-MtgxR1597Btlr/Mmmh
Stock Number:
039634-MU
Citation ID:
RRID:MMRRC_039634-MU
Other Names:
R1597 (G1), C57BL/6J-MtgxR1597Btlr
Major Collection:

Strain Information

Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, OB-cadherin, Cad11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, 6030440P17Rik, my, ne, b2b1562Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242022
Homologene: 18454
Mtss1
Name: MTSS I-BAR domain containing 1
Synonyms: MIM, D130001D01Rik, 2310003N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211401
VEGA: 15
Homologene: 8841
Taok1
Name: TAO kinase 1
Synonyms: D130018F14Rik, 2810468K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216965
Homologene: 27041
Polr2a
Name: polymerase (RNA) II (DNA directed) polypeptide A
Synonyms: 220kDa, Rpo2-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20020
HGNC: HGNC:9187
Homologene: 721
U2surp
Name: U2 snRNP-associated SURP domain containing
Synonyms: 2610101N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67958
Homologene: 13964
Ttc27
Name: tetratricopeptide repeat domain 27
Synonyms: 2610511O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74196
VEGA: 17
Homologene: 41191
Fbxl17
Name: F-box and leucine-rich repeat protein 17
Synonyms: Fbx13, C130023C01Rik, 6330576B01Rik, Fbxo13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 50758
Homologene: 79859
Ppfibp2
Name: PTPRF interacting protein, binding protein 2 (liprin beta 2)
Synonyms: liprin beta 2, Cclp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19024
HGNC: HGNC:9250
Homologene: 7486
Kif15
Name: kinesin family member 15
Synonyms: N-10 kinesin, HKLP2, 3930402I10Rik, 3110023M17Rik, Knsl7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 209737
VEGA: 9
Homologene: 23210
Mdc1
Name: mediator of DNA damage checkpoint 1
Synonyms: NFBD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240087
Homologene: 67092
Atp1b1
Name: ATPase, Na+/K+ transporting, beta 1 polypeptide
Synonyms: sodium/potassium ATPase beta subunit, Atpb, Atpb-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11931
HGNC: HGNC:804
Homologene: 37509
Kif18a
Name: kinesin family member 18A
Synonyms: N-8 kinesin, B130001M12Rik, gcd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228421
Homologene: 41820
Unc13d
Name: unc-13 homolog D
Synonyms: Munc13-4, 2610108D09Rik, Jinx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70450
Homologene: 26714
Mcm10
Name: minichromosome maintenance 10 replication initiation factor
Synonyms: C330019M07Rik, 2410041F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70024
Homologene: 41275
N4bp2
Name: NEDD4 binding protein 2
Synonyms: LOC333789, LOC386488, B3bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
Syn3
Name: synapsin III
Synonyms: Synapsin IIIa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27204
Homologene: 68320
Ap1s1
Name: adaptor protein complex AP-1, sigma 1
Synonyms: AP19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11769
HGNC: HGNC:559
Homologene: 20342
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231329
HGNC: HGNC:9188
Homologene: 722
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: l(7)-3Rn, Ten-m4, Doc4, l7Rn3, ELM2, Odz4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23966
Homologene: 8034
Atad3a
Name: ATPase family, AAA domain containing 3A
Synonyms: Tob3, 2400004H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108888
Homologene: 10059
Tnc
Name: tenascin C
Synonyms: Hxb, TN-C, TN, C130033P17Rik, tenascin-C, cytotactin, hexabrachion
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52397
Homologene: 12971
Lrch3
Name: leucine-rich repeats and calponin homology (CH) domain containing 3
Synonyms: LOC385628, 2210409B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70144
Homologene: 13111
Ddhd2
Name: DDHD domain containing 2
Synonyms: SAMWD1, 2010305K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72108
Homologene: 66646
Zfp386
Name: zinc finger protein 386 (Kruppel-like)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56220
Homologene: 51668
Pcdhb18
Name: protocadherin beta 18
Synonyms: Pcdhb9, PcdhbR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93889
Homologene: 137649
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54403
Homologene: 55776
Me2
Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Synonyms: D030040L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107029
VEGA: 18
HGNC: HGNC:6984
Homologene: 37615
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: MBC, CED-5, Hch
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Tnik
Name: TRAF2 and NCK interacting kinase
Synonyms: 4831440I19Rik, 1500031A17Rik, C530008O15Rik, C630040K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 665113
Homologene: 77943
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: eNOS, ecNOS, Nos-3, 2310065A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Acta2
Name: actin alpha 2, smooth muscle, aorta
Synonyms: Actvs, a-SMA, 0610041G09Rik, SMalphaA, alphaSMA, SMAalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11475
VEGA: 19
HGNC: HGNC:130
Homologene: 133938
Psmd5
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
Synonyms: S5b, 1500032A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66998
HGNC: HGNC:9563
Homologene: 37999
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104271
Homologene: 12837
Klhl1
Name: kelch-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 93688
HGNC: HGNC:6352
Homologene: 56903
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Mx1
Name: MX dynamin-like GTPase 1
Synonyms: myxovirus (influenza) resistance 1 polypeptide, Mx-1, Mx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17857
HGNC: HGNC:7532
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC6, SPC6, PC5A, PC5/6A, b2b585Clo, b2b1549Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Tgfbi
Name: transforming growth factor, beta induced
Synonyms: bIG-h3, 68kDa, Beta-ig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21810
VEGA: 13
Homologene: 37294
Ermap
Name: erythroblast membrane-associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 27028
Homologene: 22782
Gas6
Name: growth arrest specific 6
Synonyms: growth arrest-specific, GAS 6, Gas-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14456
HGNC: HGNC:4168
Homologene: 638
Ifngr1
Name: interferon gamma receptor 1
Synonyms: CD119, Nktar, Ifgr, Ifngr, IFN-gamma R, IFN-gammaR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15979
HGNC: HGNC:5439
Homologene: 359
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: Nav1.5c, Nav1.5, mH1, SkM2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20271
Homologene: 22738
Rapgef5
Name: Rap guanine nucleotide exchange factor (GEF) 5
Synonyms: mr-gef, D030051B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217944
VEGA: 12
Homologene: 56563
Tmem62
Name: transmembrane protein 62
Synonyms: B830009D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 96957
Homologene: 11801
Aox1
Name: aldehyde oxidase 1
Synonyms: retinal oxidase, Aox-2, Aox-1, Aox2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11761
HGNC: HGNC:553
Homologene: 68165
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: D230007K08Rik, Caterpiller 16.2, CLR16.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268857
Homologene: 18720
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226250
Homologene: 13057
Tecpr1
Name: tectonin beta-propeller repeat containing 1
Synonyms: 2210010N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70381
Homologene: 9120
Or52a5
Name: olfactory receptor family 52 subfamily A member 5
Synonyms: 3'[b]2, MOR22-3, GA_x6K02T2PBJ9-6504436-6503489, Olfr68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18369
Homologene: 130658
Mup5
Name: major urinary protein 5
Synonyms: Mup V
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17844
Homologene: 74304
Pabpc2
Name: poly(A) binding protein, cytoplasmic 2
Synonyms: Pabp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 18459
Homologene: 56509
Ube4a
Name: ubiquitination factor E4A
Synonyms: UFD2b, 9930123J21Rik, 4732444G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 140630
Homologene: 3517
Gopc
Name: golgi associated PDZ and coiled-coil motif containing
Synonyms: GOPC1, 2210402P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 94221
VEGA: 10
Homologene: 10695
Cel
Name: carboxyl ester lipase
Synonyms: BAL, 1810036E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12613
HGNC: HGNC:1848
Homologene: 37529
Zfyve16
Name: zinc finger, FYVE domain containing 16
Synonyms: B130024H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218441
Homologene: 8826
Skida1
Name: SKI/DACH domain containing 1
Synonyms: 5730507N06Rik, 2810030E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72668
Homologene: 66327
Lrriq4
Name: leucine-rich repeats and IQ motif containing 4
Synonyms: 4930558O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68307
Homologene: 12260
Fbh1
Name: F-box DNA helicase 1
Synonyms: Fbx18, Fbxo18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50755
Homologene: 9272
Birc7
Name: baculoviral IAP repeat-containing 7 (livin)
Synonyms: ML-IAP, Livin, KIAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329581
Homologene: 51405
Psme1
Name: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Synonyms: PA28a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19186
HGNC: HGNC:9568
Homologene: 4560
Btnl2
Name: butyrophilin-like 2
Synonyms: butyrophylin-like MHC class II associated, BTL-II, NG9, BTLN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 547431
HGNC: HGNC:1142
Homologene: 10482
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233445
Homologene: 115466
Rpe65
Name: retinal pigment epithelium 65
Synonyms: A930029L06Rik, Mord1, rd12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19892
Homologene: 20108
Col10a1
Name: collagen, type X, alpha 1
Synonyms: Col10a-1, Col10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12813
HGNC: HGNC:2185
Homologene: 55466
Rela
Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Synonyms: p65 NF kappaB, p65
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19697
HGNC: HGNC:9955
Homologene: 32064
Itga7
Name: integrin alpha 7
Synonyms: [a]7, alpha7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16404
VEGA: 10
HGNC: HGNC:6143
Homologene: 37592
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Gzma
Name: granzyme A
Synonyms: serine esterase 1, TSP1, BLT esterase, Hanukah factor, Ctla-3, Hf, Ctla3, H factor, SE1, TSP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14938
VEGA: 13
HGNC: HGNC:4708
Homologene: 21237
Spaca7
Name: sperm acrosome associated 7
Synonyms: 1700094C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78634
Homologene: 49754
Galm
Name: galactose mutarotase
Synonyms: aldose 1-epimerase, A530057M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 319625
Homologene: 71795
Cwc25
Name: CWC25 spliceosome-associated protein
Synonyms: R75228, 1300013D05Rik, Ccdc49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67480
Homologene: 135922
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 58,047,167 bp
  • G to T, chromosome 1 at 164,438,320 bp
  • A to C, chromosome 1 at 194,749,306 bp
  • A to T, chromosome 2 at 4,998,752 bp
  • A to T, chromosome 2 at 11,763,036 bp
  • T to C, chromosome 2 at 18,046,332 bp
  • G to T, chromosome 2 at 28,560,467 bp
  • A to G, chromosome 2 at 34,867,023 bp
  • A to G, chromosome 2 at 109,292,991 bp
  • G to A, chromosome 2 at 120,984,362 bp
  • T to C, chromosome 2 at 180,929,181 bp
  • T to C, chromosome 3 at 28,604,269 bp
  • C to G, chromosome 3 at 30,650,888 bp
  • T to C, chromosome 3 at 53,654,519 bp
  • T to A, chromosome 3 at 159,614,784 bp
  • A to T, chromosome 4 at 61,835,080 bp
  • A to G, chromosome 4 at 64,006,384 bp
  • A to T, chromosome 4 at 119,183,955 bp
  • A to T, chromosome 4 at 155,751,435 bp
  • A to T, chromosome 5 at 24,368,997 bp
  • C to T, chromosome 5 at 65,807,140 bp
  • A to G, chromosome 5 at 77,326,101 bp
  • G to A, chromosome 5 at 89,135,728 bp
  • A to T, chromosome 5 at 106,638,333 bp
  • A to T, chromosome 5 at 137,043,241 bp
  • A to G, chromosome 5 at 144,214,310 bp
  • T to C, chromosome 7 at 85,624,144 bp
  • T to A, chromosome 7 at 96,902,989 bp
  • A to G, chromosome 7 at 103,778,060 bp
  • G to A, chromosome 7 at 107,685,848 bp
  • G to T, chromosome 8 at 12,580,991 bp
  • T to C, chromosome 8 at 13,493,901 bp
  • A to G, chromosome 8 at 25,749,741 bp
  • A to G, chromosome 8 at 33,571,483 bp
  • A to T, chromosome 8 at 102,650,711 bp
  • A to T, chromosome 9 at 44,929,766 bp
  • C to T, chromosome 9 at 95,481,740 bp
  • C to A, chromosome 9 at 119,562,497 bp
  • A to G, chromosome 9 at 122,994,009 bp
  • C to T, chromosome 10 at 19,609,342 bp
  • A to G, chromosome 10 at 34,395,078 bp
  • A to G, chromosome 10 at 52,346,244 bp
  • T to C, chromosome 10 at 76,483,226 bp
  • G to T, chromosome 10 at 86,135,044 bp
  • A to G, chromosome 10 at 128,946,863 bp
  • T to C, chromosome 11 at 34,704,647 bp
  • A to G, chromosome 11 at 69,739,929 bp
  • A to G, chromosome 11 at 77,579,800 bp
  • C to T, chromosome 11 at 97,748,133 bp
  • T to C, chromosome 11 at 116,074,436 bp
  • C to A, chromosome 11 at 118,103,498 bp
  • T to C, chromosome 12 at 116,060,089 bp
  • C to T, chromosome 12 at 117,658,320 bp
  • T to A, chromosome 13 at 56,632,191 bp
  • T to A, chromosome 13 at 92,508,247 bp
  • T to A, chromosome 13 at 113,095,797 bp
  • A to G, chromosome 14 at 55,580,765 bp
  • A to T, chromosome 14 at 96,201,211 bp
  • A to G, chromosome 15 at 58,943,711 bp
  • T to A, chromosome 16 at 3,963,995 bp
  • T to A, chromosome 16 at 5,107,574 bp
  • C to T, chromosome 16 at 32,950,411 bp
  • T to A, chromosome 16 at 97,455,129 bp
  • T to C, chromosome 17 at 34,363,237 bp
  • T to A, chromosome 17 at 35,845,866 bp
  • T to C, chromosome 17 at 63,487,818 bp
  • T to A, chromosome 17 at 74,863,407 bp
  • T to C, chromosome 17 at 80,127,916 bp
  • A to G, chromosome 18 at 37,491,767 bp
  • A to G, chromosome 18 at 39,773,900 bp
  • A to T, chromosome 18 at 73,797,945 bp
  • G to A, chromosome 19 at 5,645,331 bp
  • T to A, chromosome 19 at 17,436,600 bp
  • A to T, chromosome 19 at 18,827,524 bp
  • A to T, chromosome 19 at 34,252,583 bp
  • T to C, chromosome 19 at 56,914,449 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1597 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039634-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.