Strain Name:
C57BL/6J-MtgxR1633Btlr/Mmmh
Stock Number:
039670-MU
Citation ID:
RRID:MMRRC_039670-MU
Other Names:
R1633 (G1), C57BL/6J-MtgxR1633Btlr
Major Collection:

Gene Information

Nedd4
Name: neural precursor cell expressed, developmentally down-regulated 4
Synonyms: Nedd4-1, Nedd4a, Nedd4, E430025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17999
HGNC: HGNC:7727
Homologene: 134533
Pax6
Name: paired box 6
Synonyms: Pax-6, 1500038E17Rik, Dickie's small eye, Dey, Gsfaey11, AEY11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18508
HGNC: HGNC:8620
Homologene: 1212
Bpifb3
Name: BPI fold containing family B, member 3
Synonyms: Rya3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 378700
Homologene: 18807
Ess2
Name: ess-2 splicing factor
Synonyms: Es2el, D16H22S1269E, Dgsi, ES2, Dgcr14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27886
VEGA: 16
Homologene: 11184
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: NMF335, Nav1.6, mnd-2, NaCh6, motor end-plate disease, nmf2, seal, ataxia 3, mnd2, nur14, nmf58, C630029C19Rik, med, nmf335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20273
Homologene: 7927
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy, D5Ertd66e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72145
Homologene: 22855
Ccar1
Name: cell division cycle and apoptosis regulator 1
Synonyms: 2610511G16Rik, 9430036H15Rik, Carp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67500
VEGA: 10
Homologene: 10086
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D15F32S1h, D7H15F37S1, jdf2, rjs, D7H15F32S1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 208836
Homologene: 49530
Rad50
Name: RAD50 double strand break repair protein
Synonyms: Mrell, Rad50l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19360
HGNC: HGNC:9816
Homologene: 38092
Zfp442
Name: zinc finger protein 442
Synonyms: OTTMUSG00000015730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668923
Homologene: 136215
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: LL5A, D330037A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102693
Homologene: 15903
Zfp180
Name: zinc finger protein 180
Synonyms: D130011P11, HHZ168, 2310040I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210135
Homologene: 8306
Stk3
Name: serine/threonine kinase 3
Synonyms: mess1, MST, 0610042I06Rik, Mst2, Ste20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56274
Homologene: 48420
Arel1
Name: apoptosis resistant E3 ubiquitin protein ligase 1
Synonyms: 1110018G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68497
Homologene: 8885
Eif5
Name: eukaryotic translation initiation factor 5
Synonyms: D12Ertd549e, 2810011H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217869
VEGA: 12
HGNC: HGNC:3299
Homologene: 49610
Srf
Name: serum response factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20807
VEGA: 17
Homologene: 31135
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: BC016423, Fam208b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
Synonyms: ppGaNTase-T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14426
HGNC: HGNC:4126
Homologene: 74511
Enpp3
Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms: CD203c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209558
VEGA: 10
HGNC: HGNC:3358
Homologene: 3683
Gdpd5
Name: glycerophosphodiester phosphodiesterase domain containing 5
Synonyms: Gde2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233552
Homologene: 32741
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: CD222, IGF-II/CI-MPR, CI-MPR, mannose-6-phosphate receptor, cation independent, Mpr300, M6P/IGF2R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Reck
Name: reversion-inducing-cysteine-rich protein with kazal motifs
Synonyms: St15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53614
Homologene: 9622
Edrf1
Name: erythroid differentiation regulatory factor 1
Synonyms: 2700050L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 214764
Homologene: 27985
Nipal3
Name: NIPA-like domain containing 3
Synonyms: Npal3, 9130020G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74552
Homologene: 10722
Nadk
Name: NAD kinase
Synonyms: 4432404C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 192185
Homologene: 49724
Dock8
Name: dedicator of cytokinesis 8
Synonyms: 1200017A24Rik, A130095G14Rik, 5830472H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76088
VEGA: 19
Homologene: 52414
Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
Synonyms: ECaC1, CaT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194352
HGNC: HGNC:3145
Homologene: 10520
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh4, Zfh-4, C130041O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Rdh10
Name: retinol dehydrogenase 10 (all-trans)
Synonyms: 3110069K09Rik, m366Asp, 4921506A21Rik, D1Ertd762e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98711
Homologene: 14061
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: hy-3, hy3, hyrh, 4930545D19Rik, 1700034M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244653
Homologene: 52118
Dusp19
Name: dual specificity phosphatase 19
Synonyms: TS-DSP1, SKRP1, C79103, 5930436K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68082
Homologene: 41565
Wdr95
Name: WD40 repeat domain 95
Synonyms: 4930434E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381693
Homologene: 124480
AC159748.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Stxbp4
Name: syntaxin binding protein 4
Synonyms: 6030470M02Rik, Synip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20913
Homologene: 7963
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Tmem63a
Name: transmembrane protein 63a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208795
Homologene: 101673
Ggt7
Name: gamma-glutamyltransferase 7
Synonyms: 6330563L03Rik, Ggtl3, 1110017C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 207182
HGNC: HGNC:4259
Homologene: 70866
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Tram2
Name: translocating chain-associating membrane protein 2
Synonyms: C330003D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 170829
Homologene: 8183
Cep162
Name: centrosomal protein 162
Synonyms: 4922501C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382090
Homologene: 8930
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330267
Homologene: 46582
Vmn2r79
Name: vomeronasal 2, receptor 79
Synonyms: EG621430
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 621430
Homologene: 115466
Cacna2d1
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms: Cacna2, Ca(v)alpha2delta1, Cchl2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12293
HGNC: HGNC:1399
Homologene: 579
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319719
Homologene: 131217
Cttnbp2
Name: cortactin binding protein 2
Synonyms: 9130022E09Rik, 3010022N24Rik, ORF4, 4732477G22Rik, Cortbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30785
Homologene: 14125
Cpt1b
Name: carnitine palmitoyltransferase 1b, muscle
Synonyms: M-CPTI, Cpt1, M-CPT I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12895
HGNC: HGNC:2329
Homologene: 22548
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Itih3
Name: inter-alpha trypsin inhibitor, heavy chain 3
Synonyms: Itih-3, Intin3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16426
HGNC: HGNC:6168
Homologene: 1669
Olfr15
Name: olfactory receptor 15
Synonyms: OR3, GA_x54KRFPKG5P-348087-349025, MOR256-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 18312
HGNC: HGNC:8242
Homologene: 7459
Tspyl5
Name: testis-specific protein, Y-encoded-like 5
Synonyms: E130308C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239364
VEGA: 15
Homologene: 14134
Gm5884
Name: predicted pseudogene 5884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545878
AC133939.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Acsl6
Name: acyl-CoA synthetase long-chain family member 6
Synonyms: Facl6, A330035H04Rik, Lacsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216739
Homologene: 100939
Acmsd
Name: amino carboxymuconate semialdehyde decarboxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 266645
Homologene: 44520
Vezt
Name: vezatin, adherens junctions transmembrane protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215008
Homologene: 9739
Olfr98
Name: olfactory receptor 98
Synonyms: MOR156-4, GA_x6K02T2PSCP-1703582-1702653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258503
Homologene: 133051
Olfr364-ps1
Name: olfactory receptor 364, pseudogene 1
Synonyms: GA_x6K02T2NLDC-33831282-33832243, MOR138-4P, MOR138-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227794
HGNC: HGNC:8216
Pdilt
Name: protein disulfide isomerase-like, testis expressed
Synonyms: 1700007B13Rik, PDILT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71830
Homologene: 18382
Rdh12
Name: retinol dehydrogenase 12
Synonyms: A930033N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77974
Homologene: 110830
Mepe
Name: matrix extracellular phosphoglycoprotein with ASARM motif (bone)
Synonyms: OF45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 94111
Homologene: 10623
CAAA01066805.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
C630004L07Rik
Name: RIKEN cDNA C630004L07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Sult2a1
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Synonyms: Std, Sth1, mSTa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20859
Homologene: 37741
Nkx2-9
Name: NK2 homeobox 9
Synonyms: Nkx-2.9, tinman, Nkx2.9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18094
Homologene: 7444
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 16,128,196 bp
  • A to T, chromosome 1 at 21,003,922 bp
  • C to T, chromosome 1 at 127,753,855 bp
  • A to T, chromosome 1 at 153,141,698 bp
  • T to A, chromosome 1 at 180,948,826 bp
  • T to A, chromosome 2 at 37,146,971 bp
  • T to C, chromosome 2 at 80,621,255 bp
  • A to T, chromosome 2 at 105,691,718 bp
  • A to T, chromosome 2 at 150,408,340 bp
  • T to A, chromosome 2 at 153,922,584 bp
  • C to T, chromosome 2 at 155,502,688 bp
  • A to T, chromosome 3 at 5,400,413 bp
  • T to C, chromosome 4 at 43,922,964 bp
  • C to A, chromosome 4 at 135,447,348 bp
  • T to C, chromosome 4 at 141,238,560 bp
  • C to T, chromosome 4 at 155,577,185 bp
  • T to A, chromosome 4 at 156,245,293 bp
  • A to G, chromosome 5 at 7,179,513 bp
  • T to A, chromosome 5 at 16,320,116 bp
  • A to C, chromosome 5 at 101,981,548 bp
  • G to T, chromosome 5 at 104,337,674 bp
  • A to T, chromosome 5 at 149,593,172 bp
  • G to T, chromosome 6 at 12,471,104 bp
  • A to T, chromosome 6 at 18,435,167 bp
  • A to T, chromosome 6 at 41,675,920 bp
  • A to T, chromosome 6 at 128,646,065 bp
  • A to G, chromosome 7 at 13,801,426 bp
  • A to G, chromosome 7 at 24,104,801 bp
  • G to A, chromosome 7 at 56,229,369 bp
  • T to A, chromosome 7 at 79,405,193 bp
  • T to C, chromosome 7 at 87,037,834 bp
  • T to C, chromosome 7 at 99,448,513 bp
  • T to G, chromosome 7 at 119,487,994 bp
  • T to C, chromosome 7 at 133,652,140 bp
  • T to A, chromosome 8 at 110,506,982 bp
  • T to A, chromosome 9 at 44,718,322 bp
  • G to A, chromosome 9 at 72,671,257 bp
  • T to C, chromosome 9 at 87,203,683 bp
  • A to G, chromosome 10 at 5,349,388 bp
  • T to C, chromosome 10 at 24,795,782 bp
  • T to C, chromosome 10 at 62,751,014 bp
  • T to A, chromosome 10 at 93,984,276 bp
  • T to C, chromosome 10 at 99,109,952 bp
  • C to T, chromosome 11 at 53,692,859 bp
  • T to C, chromosome 11 at 54,328,398 bp
  • A to G, chromosome 11 at 90,540,160 bp
  • T to C, chromosome 11 at 116,007,760 bp
  • T to C, chromosome 12 at 56,612,981 bp
  • A to T, chromosome 12 at 79,218,724 bp
  • A to G, chromosome 12 at 84,926,283 bp
  • T to A, chromosome 12 at 111,540,287 bp
  • A to T, chromosome 13 at 3,581,771 bp
  • G to A, chromosome 13 at 54,525,231 bp
  • T to A, chromosome 14 at 30,917,398 bp
  • T to C, chromosome 14 at 31,150,380 bp
  • T to A, chromosome 15 at 33,686,645 bp
  • T to C, chromosome 15 at 34,959,060 bp
  • T to C, chromosome 15 at 89,418,815 bp
  • A to G, chromosome 15 at 101,029,815 bp
  • A to C, chromosome 16 at 3,839,532 bp
  • A to G, chromosome 16 at 17,909,967 bp
  • A to C, chromosome 17 at 12,726,309 bp
  • T to A, chromosome 17 at 37,263,662 bp
  • A to T, chromosome 17 at 46,551,608 bp
  • A to G, chromosome 19 at 25,051,563 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1633 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039670-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.