Strain Name:
C57BL/6J-MtgxR1663Btlr/Mmmh
Stock Number:
039699-MU
Citation ID:
RRID:MMRRC_039699-MU
Other Names:
R1663 (G1), C57BL/6J-MtgxR1663Btlr
Major Collection:

Strain Information

Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: beta fodrin, Spnb-2, spectrin G, brain spectrin, elf3, elf1, 9930031C03Rik, non-erythrocytic, Spnb2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20742
Homologene: 2354
Notch3
Name: notch 3
Synonyms: hpbk, N3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Zmynd8
Name: zinc finger, MYND-type containing 8
Synonyms: 2010005I16Rik, 1110013E22Rik, ZMYND8, RACK7, 3632413B07Rik, Prkcbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228880
HGNC: HGNC:9397
Homologene: 32679
Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320938
Homologene: 40848
Cdc42ep4
Name: CDC42 effector protein 4
Synonyms: CEP4, Borg4, 1500041M20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56699
Homologene: 8110
Comp
Name: cartilage oligomeric matrix protein
Synonyms: thrombospondin-5, TSP5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12845
HGNC: HGNC:2227
Homologene: 74
Nisch
Name: nischarin
Synonyms: 1200007D05Rik, 3202002H23Rik, edsn
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 64652
Homologene: 136161
Drd5
Name: dopamine receptor D5
Synonyms: DRD1b, Drd-5, Gpcr1, Drd1b, D5R
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Nbea
Name: neurobeachin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Brd7
Name: bromodomain containing 7
Synonyms: bromodomain protein 75 kDa, BP75, CELTIX1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26992
Homologene: 8085
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Helb
Name: helicase (DNA) B
Synonyms: D10Ertd664e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 117599
Homologene: 50463
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: ATFa-associated Modulator, AM, 2610204M12Rik, Mcaf1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54343
Homologene: 10051
Pip5k1c
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
Synonyms: PIP5KIgamma
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18717
HGNC: HGNC:8996
Homologene: 69032
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: 2500002A22Rik, Smc4l1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70099
Homologene: 4015
Ccdc18
Name: coiled-coil domain containing 18
Synonyms: 1700021E15Rik, 4932411G06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73254
Homologene: 35455
Cc2d1b
Name: coiled-coil and C2 domain containing 1B
Synonyms: A830039B04Rik, Freud2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 319965
Homologene: 70951
Rad50
Name: RAD50 double strand break repair protein
Synonyms: Rad50l, Mrell
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19360
HGNC: HGNC:9816
Homologene: 38092
Strn3
Name: striatin, calmodulin binding protein 3
Synonyms: SG2NA
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 94186
VEGA: 12
Homologene: 82078
Nbn
Name: nibrin
Synonyms: Nbs1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 27354
HGNC: HGNC:7652
Homologene: 1858
Mtmr2
Name: myotubularin related protein 2
Synonyms: 6030445P13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77116
HGNC: HGNC:7450
Homologene: 22951
Dcc
Name: deleted in colorectal carcinoma
Synonyms: C030036D22Rik, Igdcc1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13176
HGNC: HGNC:2701
Homologene: 21081
Hnrnpc
Name: heterogeneous nuclear ribonucleoprotein C
Synonyms: hnRNP C2, hnRNP C1, hnRNPC2, hnRNPC1, D14Wsu171e, Hnrpc2, Hnrpc1, Hnrpc
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 15381
VEGA: 14
HGNC: HGNC:5035
Homologene: 74524
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 672125
Homologene: 129606
Spink6
Name: serine peptidase inhibitor, Kazal type 6
Synonyms: EG433180
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 433180
VEGA: 18
Cldn14
Name: claudin 14
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56173
HGNC: HGNC:2035
Homologene: 8115
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101202
Homologene: 18724
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: Min, CC1, adenomatosis polyposis coli
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Nucb1
Name: nucleobindin 1
Synonyms: MTEST82, B230337F23Rik, Calnuc
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18220
HGNC: HGNC:8043
Homologene: 4507
Prkag1
Name: protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Synonyms: Prkaac
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19082
VEGA: 15
HGNC: HGNC:9385
Homologene: 99712
Pnisr
Name: PNN interacting serine/arginine-rich
Synonyms: 5730406M06Rik, Sfrs18
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66625
Homologene: 32802
Atl2
Name: atlastin GTPase 2
Synonyms: Aip-2, 2010110I21Rik, Arl6ip2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 56298
VEGA: 17
Homologene: 56949
Dync2i1
Name: dynein 2 intermediate chain 1
Synonyms: D430033N04Rik, Wdr60, Dync2l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217935
VEGA: 12
Homologene: 23067
Tmem81
Name: transmembrane protein 81
Synonyms: 4930429O20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74626
Homologene: 12579
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Gipc2
Name: GIPC PDZ domain containing family, member 2
Synonyms: 2200002N01Rik, Semcap2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54120
Homologene: 22994
Enam
Name: enamelin
Synonyms: abte
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13801
HGNC: HGNC:3344
Homologene: 9698
Krt74
Name: keratin 74
Synonyms: Kb37
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 406222
VEGA: 15
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Mccc1
Name: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Synonyms: MCCalpha, MCCA, 1810045E08Rik, 2310058B18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72039
HGNC: HGNC:6936
Homologene: 10603
Wdr87-ps
Name: WD repeat domain 87, pseudogene
Synonyms: 4932431P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114675
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, KCP, Crim2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 333088
Homologene: 87817
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 672511
Homologene: 45439
Aplnr
Name: apelin receptor
Synonyms: msr/apj, apelin receptor, APJ, Agtrl1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 23796
HGNC: HGNC:339
Homologene: 3784
Zfp605
Name: zinc finger protein 605
Synonyms: A830023I12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 675812
Homologene: 52335
Clspn
Name: claspin
Synonyms: E130314M08Rik, C85083
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269582
Homologene: 11138
Vmn2r19
Name: vomeronasal 2, receptor 19
Synonyms: EG232358
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232358
Homologene: 84037
Ly75
Name: lymphocyte antigen 75
Synonyms: DEC-205, CD205
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17076
Homologene: 31085
Arhgef5
Name: Rho guanine nucleotide exchange factor 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54324
Homologene: 66300
Sema3a
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Synonyms: SemD, semaphorin III, sema III, collapsin-1, Semad
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20346
Homologene: 31358
Ankrd36
Name: ankyrin repeat domain 36
Synonyms: 1700012M14Rik, GC3, 1700008J08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76389
Homologene: 137366
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215772
Homologene: 100289
Mmp1a
Name: matrix metallopeptidase 1a (interstitial collagenase)
Synonyms: Mcol-A
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83995
VEGA: 9
HGNC: HGNC:7155
Homologene: 20544
Or6c6c
Name: olfactory receptor family 6 subfamily C member 6C
Synonyms: GA_x6K02T2PULF-11383575-11384519, MOR110-7, Olfr804
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258068
Homologene: 133581
Tecpr1
Name: tectonin beta-propeller repeat containing 1
Synonyms: 2210010N04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70381
Homologene: 9120
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 65020
Homologene: 129707
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226438
Homologene: 130054
Rims3
Name: regulating synaptic membrane exocytosis 3
Synonyms: Rim3, Nim3, A730060M23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242662
Homologene: 8837
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: 1300008P06Rik, 2810025E10Rik, D1Ertd161e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52231
Homologene: 41225
Eno3
Name: enolase 3, beta muscle
Synonyms: Eno-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13808
HGNC: HGNC:3354
Homologene: 68215
Zfp52
Name: zinc finger protein 52
Synonyms: zfec29, Zfp-52, KRAB11, Zfp76
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22710
VEGA: 17
Homologene: 77326
Zswim5
Name: zinc finger SWIM-type containing 5
Synonyms: 4933426E21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74464
Homologene: 18958
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: YSPL3, SVCT2, Slc23a1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54338
Homologene: 68440
Fam13a
Name: family with sequence similarity 13, member A
Synonyms: D430015B01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58909
Homologene: 135847
Apol10b
Name: apolipoprotein L 10B
Synonyms: 9130218O11Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328561
Homologene: 129975
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74682
Homologene: 10814
Or8b44
Name: olfactory receptor family 8 subfamily B member 44
Synonyms: GA_x6K02T2PVTD-32204729-32205661, MOR165-5, Olfr907
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258801
VEGA: 9
Homologene: 27268
Rnf170
Name: ring finger protein 170
Synonyms: 6720407G21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 77733
Homologene: 12807
Hk3
Name: hexokinase 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212032
HGNC: HGNC:4925
Homologene: 55633
Gzmg
Name: granzyme G
Synonyms: Ctla-7, Ctla7
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14944
VEGA: 14
Homologene: 133275
Or1l8
Name: olfactory receptor family 1 subfamily L member 8
Synonyms: GA_x6K02T2NLDC-33622642-33621710, MOR138-2, Olfr355
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258618
Homologene: 132326
Or7g12
Name: olfactory receptor family 7 subfamily G member 12
Synonyms: GA_x6K02T2PVTD-12724921-12725859, MOR153-2, MOR153-4_p, Olfr834
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258074
HGNC: HGNC:8467
Homologene: 128143
Ndufb8
Name: NADH:ubiquinone oxidoreductase subunit B8
Synonyms: 2900010I05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67264
HGNC: HGNC:7703
Homologene: 3668
Zfp964
Name: zinc finger protein 964
Synonyms: Gm7187
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 636741
Homologene: 130114
Adam3
Name: ADAM metallopeptidase domain 3
Synonyms: Taz83, tMDC, Cyrn1, ADAM3, Taz83
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11497
HGNC: HGNC:209
Homologene: 69052
Tll1
Name: tolloid-like
Synonyms: Tll-1, b2b2476Clo
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21892
Homologene: 49202
Kank3
Name: KN motif and ankyrin repeat domains 3
Synonyms: 0610013D04Rik, D17Ertd288e, Ankrd47
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 80880
Homologene: 12749
Hao1
Name: hydroxyacid oxidase 1, liver
Synonyms: GOX, Hao-1, Gox1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15112
HGNC: HGNC:4809
Homologene: 6578
Dcstamp
Name: dendrocyte expressed seven transmembrane protein
Synonyms: 4833414I07Rik, DC-STAMP, Tm7sf4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75766
VEGA: 15
Homologene: 12769
Arrb2
Name: arrestin, beta 2
Synonyms: beta arr2, beta-arrestin-2, beta-arrestin2, arrestin 3, Arr3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216869
HGNC: HGNC:712
Homologene: 3183
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 14,889,502 bp
  • T to C, chromosome 1 at 34,163,385 bp
  • C to T, chromosome 1 at 75,196,270 bp
  • C to T, chromosome 1 at 132,507,897 bp
  • C to T, chromosome 1 at 135,968,308 bp
  • T to C, chromosome 2 at 27,951,476 bp
  • T to A, chromosome 2 at 29,126,905 bp
  • T to G, chromosome 2 at 36,927,334 bp
  • T to C, chromosome 2 at 60,314,234 bp
  • A to G, chromosome 2 at 85,136,694 bp
  • A to G, chromosome 2 at 132,065,464 bp
  • T to C, chromosome 2 at 134,498,341 bp
  • A to G, chromosome 2 at 165,807,885 bp
  • T to C, chromosome 2 at 181,997,437 bp
  • C to A, chromosome 3 at 35,978,933 bp
  • A to G, chromosome 3 at 55,645,986 bp
  • A to G, chromosome 3 at 69,033,931 bp
  • C to T, chromosome 3 at 96,651,738 bp
  • T to A, chromosome 3 at 152,094,164 bp
  • T to A, chromosome 4 at 15,970,903 bp
  • T to A, chromosome 4 at 21,873,857 bp
  • T to C, chromosome 4 at 88,591,983 bp
  • A to G, chromosome 4 at 108,623,547 bp
  • T to A, chromosome 4 at 116,986,895 bp
  • T to C, chromosome 4 at 120,887,049 bp
  • T to A, chromosome 4 at 126,565,975 bp
  • G to A, chromosome 5 at 13,557,125 bp
  • T to C, chromosome 5 at 38,320,855 bp
  • A to T, chromosome 5 at 88,503,994 bp
  • A to G, chromosome 5 at 108,216,090 bp
  • G to A, chromosome 5 at 110,127,585 bp
  • C to A, chromosome 5 at 144,197,944 bp
  • A to T, chromosome 6 at 3,483,439 bp
  • G to T, chromosome 6 at 29,498,965 bp
  • T to C, chromosome 6 at 29,565,759 bp
  • G to A, chromosome 6 at 43,276,965 bp
  • G to A, chromosome 6 at 58,954,372 bp
  • T to A, chromosome 6 at 123,336,452 bp
  • A to G, chromosome 6 at 136,603,324 bp
  • A to G, chromosome 7 at 12,848,642 bp
  • A to T, chromosome 7 at 29,529,303 bp
  • A to G, chromosome 7 at 45,498,864 bp
  • T to A, chromosome 8 at 24,687,933 bp
  • C to T, chromosome 8 at 26,129,143 bp
  • T to A, chromosome 8 at 64,017,686 bp
  • A to G, chromosome 8 at 69,664,083 bp
  • T to C, chromosome 8 at 70,373,600 bp
  • T to C, chromosome 8 at 88,358,023 bp
  • C to T, chromosome 9 at 7,465,656 bp
  • C to T, chromosome 9 at 13,803,501 bp
  • T to A, chromosome 9 at 18,988,710 bp
  • T to G, chromosome 9 at 38,499,572 bp
  • T to C, chromosome 10 at 10,339,675 bp
  • T to C, chromosome 10 at 81,312,515 bp
  • G to T, chromosome 10 at 120,105,433 bp
  • A to T, chromosome 10 at 127,556,921 bp
  • G to A, chromosome 10 at 129,705,291 bp
  • T to A, chromosome 11 at 5,620,126 bp
  • T to C, chromosome 11 at 30,120,783 bp
  • T to C, chromosome 11 at 53,668,223 bp
  • A to T, chromosome 11 at 70,437,603 bp
  • T to C, chromosome 11 at 70,662,274 bp
  • A to T, chromosome 11 at 113,729,451 bp
  • A to G, chromosome 11 at 119,437,672 bp
  • A to G, chromosome 12 at 9,020,000 bp
  • A to G, chromosome 12 at 51,652,826 bp
  • T to C, chromosome 12 at 116,229,610 bp
  • A to T, chromosome 13 at 55,006,575 bp
  • A to G, chromosome 14 at 31,191,521 bp
  • A to G, chromosome 14 at 52,075,395 bp
  • A to T, chromosome 14 at 56,156,808 bp
  • C to T, chromosome 15 at 39,754,944 bp
  • A to T, chromosome 15 at 77,588,714 bp
  • A to G, chromosome 15 at 98,815,895 bp
  • A to T, chromosome 15 at 101,756,674 bp
  • A to G, chromosome 16 at 93,919,278 bp
  • T to C, chromosome 17 at 21,561,822 bp
  • T to C, chromosome 17 at 24,376,357 bp
  • C to T, chromosome 17 at 32,156,119 bp
  • A to G, chromosome 17 at 33,818,375 bp
  • A to G, chromosome 17 at 79,864,711 bp
  • A to G, chromosome 18 at 34,268,325 bp
  • T to G, chromosome 18 at 44,071,521 bp
  • A to T, chromosome 18 at 71,826,052 bp
  • T to C, chromosome 19 at 44,550,381 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1663 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039699-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.