Strain Name:
C57BL/6J-MtgxR1690Btlr/Mmmh
Stock Number:
039723-MU
Citation ID:
RRID:MMRRC_039723-MU
Other Names:
R1690 (G1), C57BL/6J-MtgxR1690Btlr
Major Collection:

Gene Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Htr3b
Name: 5-hydroxytryptamine (serotonin) receptor 3B
Synonyms: 5-HT3 receptor subunit B, 5-HT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57014
VEGA: 9
HGNC: HGNC:5298
Homologene: 38131
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271639
Homologene: 10188
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Pepd
Name: peptidase D
Synonyms: Pep-4, peptidase D, Pep4, dal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18624
HGNC: HGNC:8840
Homologene: 239
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 9130422G05Rik, 1810054D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69863
Homologene: 25228
Tdg
Name: thymine DNA glycosylase
Synonyms: Jza1, E130317C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21665
Homologene: 2415
Tcf12
Name: transcription factor 12
Synonyms: ME1, ALF1, HEB, HTF4, HTF-4, REB, bHLHb20, HEBAlt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21406
Homologene: 40774
Arhgap35
Name: Rho GTPase activating protein 35
Synonyms: P190 RhoGAP, 6430596G11Rik, p190RhoGAP, p190A, Grlf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232906
HGNC: HGNC:4591
Homologene: 35136
Lta4h
Name: leukotriene A4 hydrolase
Synonyms: LTA4 hydrodase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16993
VEGA: 10
HGNC: HGNC:6710
Homologene: 6820
Zc3hc1
Name: zinc finger, C3HC type 1
Synonyms: 1110054L24Rik, HSPC216, Nipa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232679
Homologene: 32315
Ttk
Name: Ttk protein kinase
Synonyms: Esk1, Mps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22137
Homologene: 2489
Smndc1
Name: survival motor neuron domain containing 1
Synonyms: 4933440I19Rik, 2410004J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76479
VEGA: 19
Homologene: 4290
Soat1
Name: sterol O-acyltransferase 1
Synonyms: ACAT-1, Acact, 8430426K15Rik, hid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20652
Homologene: 2333
Fabp3
Name: fatty acid binding protein 3, muscle and heart
Synonyms: H-FABP, Fabph-4, Fabph-1, Fabph4, Fabph1, Mdgi, Fabp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14077
HGNC: HGNC:3557
Homologene: 68379
Hnrnpk
Name: heterogeneous nuclear ribonucleoprotein K
Synonyms: hnRNPK, Hnrpk, KBBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15387
HGNC: HGNC:5044
Homologene: 81909
Fgf15
Name: fibroblast growth factor 15
Synonyms: FGF19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14170
HGNC: HGNC:3675
Homologene: 3754
Fgf21
Name: fibroblast growth factor 21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56636
HGNC: HGNC:3678
Homologene: 10428
Dpf2
Name: D4, zinc and double PHD fingers family 2
Synonyms: ubi-d4, Req, 2210010M07Rik, requiem
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19708
HGNC: HGNC:9964
Homologene: 21265
Rnf41
Name: ring finger protein 41
Synonyms: 4930511A05Rik, FLRF, 4933415P08Rik, 2210404G21Rik, D10Ertd722e, Nrdp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67588
VEGA: 10
Homologene: 4226
Vit
Name: vitrin
Synonyms: 1700110E08Rik, 1700052E02Rik, 2810429K11Rik, akhirin, AKH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74199
VEGA: 17
Homologene: 24942
Me2
Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Synonyms: D030040L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107029
VEGA: 18
HGNC: HGNC:6984
Homologene: 37615
Prlr
Name: prolactin receptor
Synonyms: Pr-1, Prlr-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19116
HGNC: HGNC:9446
Homologene: 733
Nlrc4
Name: NLR family, CARD domain containing 4
Synonyms: 9530011P19Rik, Card12, Ipaf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268973
VEGA: 17
Homologene: 10924
Fam184b
Name: family with sequence similarity 184, member B
Synonyms: 9630031F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 58227
Homologene: 137353
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20272
Homologene: 55706
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Tmem202
Name: transmembrane protein 202
Synonyms: 4930425N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73893
VEGA: 9
Homologene: 52264
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Nprl2
Name: NPR2 like, GATOR1 complex subunit
Synonyms: G21, NPR2L, NPRL2, 2810446G01Rik, Tusc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56032
Homologene: 4771
Chrd
Name: chordin
Synonyms: Chd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12667
HGNC: HGNC:1949
Homologene: 2774
Ccdc88b
Name: coiled-coil domain containing 88B
Synonyms: 2610041P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 78317
VEGA: 19
Homologene: 49992
Itgal
Name: integrin alpha L
Synonyms: LFA-1, Cd11a, Ly-21, Ly-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Sh2d4a
Name: SH2 domain containing 4A
Synonyms: SH2A, 2210402M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72281
Homologene: 11117
Rab11fip2
Name: RAB11 family interacting protein 2 (class I)
Synonyms: Rab11-FIP2, nRip11, 4930470G04Rik, A830046J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74998
Homologene: 8937
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: Mdga2, 9330209L04Rik, 6720489L24Rik, Mamdc1, Adp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320772
Homologene: 45659
Pramel23
Name: PRAME like 23
Synonyms: Gm13089
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 277667
Csf2rb
Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Synonyms: AIC2B, common beta chain, CDw131, beta c, Bc, Il5rb, Il3r, Il3rb1, Csf2rb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12983
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Camk4
Name: calcium/calmodulin-dependent protein kinase IV
Synonyms: Ca2+/calmodulin-dependent protein kinase type IV/Gr, CaMKIV/Gr, CaMKIV, A430110E23Rik, D18Bwg0362e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12326
VEGA: 18
HGNC: HGNC:1464
Homologene: 100780
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, 4632415N18Rik, 4930463G05Rik, D19Ertd652e, Wdr96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100048534
Homologene: 36425
Pth2r
Name: parathyroid hormone 2 receptor
Synonyms: Pthr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213527
HGNC: HGNC:9609
Homologene: 3701
Prkcsh
Name: protein kinase C substrate 80K-H
Synonyms: 80K-H, hepatocystin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19089
VEGA: 9
HGNC: HGNC:9411
Homologene: 2056
Myrf
Name: myelin regulatory factor
Synonyms: LOC225908, LOC386531, Gm98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Fmn1
Name: formin 1
Synonyms: Fmn, formin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14260
HGNC: HGNC:3768
Homologene: 121778
Olfr1061
Name: olfactory receptor 1061
Synonyms: MOR188-1, GA_x6K02T2Q125-47883395-47882454, MOR188-9, MOR188-1, MOR188-7, Olfr1515
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259022
Homologene: 79468
AC111097.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Dtx3l
Name: deltex 3-like, E3 ubiquitin ligase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 209200
Homologene: 51375
Adgrg7
Name: adhesion G protein-coupled receptor G7
Synonyms: 9130020O16Rik, Gpr128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239853
Homologene: 13115
Taar8a
Name: trace amine-associated receptor 8A
Synonyms: LOC215859
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215859
Homologene: 77586
D17H6S53E
Name: DNA segment, Chr 17, human D6S53E
Synonyms: NG34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 114585
Homologene: 75155
Mettl17
Name: methyltransferase like 17
Synonyms: 2310032K15Rik, D14Ertd209e, Mett11d1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 52535
Homologene: 11226
Tmtc2
Name: transmembrane and tetratricopeptide repeat containing 2
Synonyms: D330034A10Rik, 8430438D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 278279
Homologene: 25521
Septin12
Name: septin 12
Synonyms: 1700028G04Rik, 4933413B09Rik, Septin12, Sept12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71089
VEGA: 16
Homologene: 69435
4930591A17Rik
Name: RIKEN cDNA 4930591A17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68175
Zfp825
Name: zinc finger protein 825
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 235956
Lipi
Name: lipase, member I
Synonyms: D930038D03Rik, lpd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320355
Homologene: 77864
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 65,372,303 bp
  • A to T, chromosome 1 at 156,444,574 bp
  • A to G, chromosome 1 at 165,519,925 bp
  • T to G, chromosome 2 at 66,675,943 bp
  • T to A, chromosome 2 at 86,413,954 bp
  • T to A, chromosome 2 at 113,525,482 bp
  • A to T, chromosome 2 at 179,415,912 bp
  • T to C, chromosome 3 at 129,800,745 bp
  • A to T, chromosome 4 at 83,227,177 bp
  • C to T, chromosome 4 at 130,312,387 bp
  • T to C, chromosome 4 at 143,698,123 bp
  • A to T, chromosome 5 at 45,532,721 bp
  • A to G, chromosome 6 at 30,390,941 bp
  • A to G, chromosome 7 at 16,563,281 bp
  • A to G, chromosome 7 at 28,911,525 bp
  • G to A, chromosome 7 at 35,031,357 bp
  • A to G, chromosome 7 at 45,614,318 bp
  • T to C, chromosome 7 at 127,302,117 bp
  • A to G, chromosome 7 at 144,899,928 bp
  • T to C, chromosome 8 at 68,294,449 bp
  • T to A, chromosome 9 at 22,010,575 bp
  • T to A, chromosome 9 at 48,937,094 bp
  • T to A, chromosome 9 at 59,519,108 bp
  • A to G, chromosome 9 at 71,870,072 bp
  • G to A, chromosome 9 at 83,844,039 bp
  • C to A, chromosome 9 at 107,542,464 bp
  • A to G, chromosome 10 at 24,076,915 bp
  • T to A, chromosome 10 at 82,638,889 bp
  • A to G, chromosome 10 at 93,035,442 bp
  • A to G, chromosome 10 at 93,484,692 bp
  • A to T, chromosome 10 at 105,348,427 bp
  • C to A, chromosome 10 at 128,435,460 bp
  • T to A, chromosome 12 at 66,513,366 bp
  • T to A, chromosome 13 at 58,400,354 bp
  • T to A, chromosome 13 at 74,480,662 bp
  • T to A, chromosome 14 at 51,891,461 bp
  • A to T, chromosome 15 at 10,317,590 bp
  • T to A, chromosome 15 at 73,262,610 bp
  • T to C, chromosome 15 at 78,348,644 bp
  • A to G, chromosome 16 at 4,988,514 bp
  • T to C, chromosome 16 at 20,734,780 bp
  • C to T, chromosome 16 at 35,933,268 bp
  • A to T, chromosome 16 at 56,795,630 bp
  • A to G, chromosome 16 at 75,541,125 bp
  • A to G, chromosome 17 at 35,127,212 bp
  • G to A, chromosome 17 at 74,437,523 bp
  • A to G, chromosome 17 at 78,624,865 bp
  • T to G, chromosome 18 at 33,179,493 bp
  • T to A, chromosome 18 at 54,987,634 bp
  • T to C, chromosome 18 at 73,797,819 bp
  • C to T, chromosome 19 at 5,905,462 bp
  • T to C, chromosome 19 at 6,857,370 bp
  • C to T, chromosome 19 at 10,219,513 bp
  • A to G, chromosome 19 at 47,751,066 bp
  • A to T, chromosome 19 at 53,383,729 bp
  • A to T, chromosome 19 at 59,937,300 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1690 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039723-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.