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Strain Name:
C57BL/6J-MtgxR1826Btlr/Mmmh
Stock Number:
039853-MU
Citation ID:
RRID:MMRRC_039853-MU
Other Names:
R1826 (G1), C57BL/6J-MtgxR1826Btlr
Major Collection:

Strain Information

Cdh1
Name: cadherin 1
Synonyms: E-cadherin, Ecad, UM, uvomorulin, L-CAM, E-cad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Gpr83
Name: G protein-coupled receptor 83
Synonyms: RP105, RP82, RP39, glucocorticoid-induced receptor, GIR, Gpr72, Gir
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14608
HGNC: HGNC:4523
Homologene: 7732
Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: NLRR-1, 2810047E21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16979
Homologene: 32036
Phf12
Name: PHD finger protein 12
Synonyms: PF1, 2410142K10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268448
Homologene: 10841
Jade1
Name: jade family PHD finger 1
Synonyms: D530048A03Rik, Phf17
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269424
Homologene: 18162
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 4930518N04Rik, neurabin-I, A230094E16Rik, 2810430P21Rik, Neurabin I, NRB
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243725
Homologene: 14247
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 73,953,634 bp
  • T to A, chromosome 1 at 91,984,699 bp
  • T to C, chromosome 1 at 150,452,009 bp
  • G to A, chromosome 1 at 183,436,344 bp
  • T to A, chromosome 1 at 192,413,068 bp
  • T to C, chromosome 2 at 59,968,733 bp
  • T to G, chromosome 3 at 41,613,213 bp
  • A to T, chromosome 3 at 93,526,121 bp
  • G to T, chromosome 3 at 104,650,939 bp
  • A to T, chromosome 3 at 142,723,179 bp
  • A to C, chromosome 3 at 146,175,472 bp
  • A to T, chromosome 4 at 94,970,686 bp
  • T to C, chromosome 4 at 110,251,292 bp
  • T to A, chromosome 4 at 120,704,504 bp
  • T to A, chromosome 4 at 139,614,065 bp
  • A to T, chromosome 4 at 145,155,003 bp
  • T to C, chromosome 4 at 155,386,486 bp
  • T to A, chromosome 4 at 156,016,279 bp
  • A to T, chromosome 5 at 26,001,242 bp
  • A to G, chromosome 5 at 33,433,933 bp
  • A to T, chromosome 5 at 97,061,402 bp
  • A to T, chromosome 5 at 114,060,056 bp
  • A to G, chromosome 5 at 120,855,589 bp
  • G to A, chromosome 5 at 125,513,906 bp
  • A to T, chromosome 5 at 135,149,975 bp
  • C to T, chromosome 5 at 150,436,709 bp
  • A to T, chromosome 6 at 5,111,060 bp
  • A to G, chromosome 6 at 29,455,185 bp
  • A to G, chromosome 6 at 30,812,842 bp
  • A to T, chromosome 6 at 107,567,568 bp
  • A to G, chromosome 6 at 123,283,632 bp
  • T to C, chromosome 7 at 24,309,115 bp
  • T to C, chromosome 7 at 25,628,763 bp
  • T to A, chromosome 7 at 27,132,562 bp
  • T to A, chromosome 7 at 51,943,673 bp
  • T to G, chromosome 7 at 64,337,466 bp
  • T to C, chromosome 7 at 80,320,218 bp
  • A to G, chromosome 7 at 102,477,513 bp
  • T to G, chromosome 7 at 105,757,627 bp
  • C to T, chromosome 7 at 116,368,117 bp
  • A to T, chromosome 7 at 126,875,838 bp
  • T to C, chromosome 7 at 128,007,844 bp
  • T to C, chromosome 8 at 3,386,913 bp
  • T to C, chromosome 8 at 11,313,509 bp
  • T to C, chromosome 8 at 12,846,154 bp
  • T to A, chromosome 8 at 43,651,342 bp
  • C to T, chromosome 8 at 54,181,312 bp
  • T to C, chromosome 8 at 68,902,291 bp
  • C to T, chromosome 8 at 77,555,674 bp
  • A to G, chromosome 8 at 104,131,091 bp
  • A to T, chromosome 8 at 105,293,618 bp
  • T to C, chromosome 8 at 106,666,266 bp
  • A to G, chromosome 8 at 129,026,759 bp
  • G to T, chromosome 9 at 14,868,333 bp
  • C to T, chromosome 9 at 54,622,556 bp
  • T to C, chromosome 9 at 72,298,780 bp
  • T to A, chromosome 9 at 107,558,193 bp
  • T to A, chromosome 9 at 107,742,414 bp
  • C to A, chromosome 9 at 109,559,714 bp
  • C to A, chromosome 9 at 110,517,633 bp
  • T to C, chromosome 9 at 114,597,621 bp
  • T to A, chromosome 9 at 116,822,868 bp
  • T to C, chromosome 10 at 24,027,576 bp
  • G to T, chromosome 10 at 34,394,649 bp
  • T to C, chromosome 10 at 53,348,812 bp
  • A to T, chromosome 10 at 127,553,707 bp
  • A to T, chromosome 11 at 29,489,637 bp
  • A to G, chromosome 11 at 43,420,366 bp
  • T to G, chromosome 11 at 54,466,164 bp
  • A to G, chromosome 11 at 55,220,453 bp
  • T to A, chromosome 11 at 58,841,431 bp
  • A to G, chromosome 11 at 70,683,308 bp
  • T to A, chromosome 11 at 71,107,980 bp
  • G to A, chromosome 11 at 71,122,747 bp
  • T to C, chromosome 11 at 78,024,954 bp
  • G to A, chromosome 11 at 94,494,079 bp
  • T to G, chromosome 11 at 100,103,030 bp
  • C to A, chromosome 11 at 115,793,213 bp
  • C to T, chromosome 11 at 120,808,499 bp
  • G to A, chromosome 12 at 4,974,094 bp
  • A to G, chromosome 12 at 34,429,492 bp
  • T to C, chromosome 12 at 57,660,247 bp
  • G to A, chromosome 12 at 71,318,344 bp
  • T to A, chromosome 12 at 79,269,049 bp
  • T to C, chromosome 12 at 86,062,044 bp
  • T to A, chromosome 12 at 112,123,418 bp
  • T to A, chromosome 12 at 113,546,122 bp
  • T to A, chromosome 13 at 3,581,759 bp
  • G to A, chromosome 13 at 43,668,534 bp
  • T to A, chromosome 13 at 54,524,639 bp
  • C to T, chromosome 13 at 104,169,819 bp
  • C to A, chromosome 14 at 23,330,929 bp
  • A to G, chromosome 14 at 26,711,019 bp
  • A to T, chromosome 14 at 65,253,106 bp
  • C to A, chromosome 15 at 11,071,520 bp
  • G to A, chromosome 15 at 26,552,765 bp
  • T to C, chromosome 15 at 39,118,899 bp
  • T to A, chromosome 15 at 44,503,345 bp
  • T to C, chromosome 15 at 80,474,281 bp
  • C to T, chromosome 15 at 83,303,102 bp
  • C to A, chromosome 16 at 4,670,587 bp
  • G to T, chromosome 16 at 33,865,560 bp
  • G to A, chromosome 16 at 48,317,348 bp
  • A to G, chromosome 16 at 87,415,616 bp
  • T to A, chromosome 16 at 93,591,299 bp
  • T to C, chromosome 16 at 97,455,637 bp
  • A to T, chromosome 17 at 17,562,836 bp
  • A to G, chromosome 17 at 28,356,367 bp
  • A to T, chromosome 17 at 33,886,561 bp
  • A to G, chromosome 17 at 76,284,423 bp
  • T to A, chromosome 17 at 78,534,676 bp
  • A to G, chromosome 17 at 88,486,805 bp
  • G to T, chromosome 17 at 88,689,974 bp
  • C to T, chromosome 18 at 5,063,383 bp
  • A to T, chromosome 18 at 21,129,452 bp
  • T to C, chromosome 18 at 35,653,575 bp
  • T to A, chromosome 18 at 37,295,985 bp
  • C to T, chromosome 18 at 37,321,469 bp
  • A to G, chromosome 18 at 54,898,576 bp
  • T to A, chromosome 18 at 65,198,740 bp
  • A to T, chromosome 19 at 11,523,934 bp
  • T to A, chromosome 19 at 13,749,347 bp
  • T to C, chromosome 19 at 43,822,014 bp
  • T to A, chromosome X at 8,880,705 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1826 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039853-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.