Strain Name:
C57BL/6J-MtgxR2029Btlr/Mmmh
Stock Number:
040036-MU
Citation ID:
RRID:MMRRC_040036-MU
Other Names:
R2029 (G1), C57BL/6J-MtgxR2029Btlr
Major Collection:

Gene Information

Gene Symbol: Figla (Mus musculus (mouse))
Name: folliculogenesis specific basic helix-loop-helix
Synonyms: bHLHc8, FIG alpha
Chromosome: 6
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:1349421
Gene Symbol: Slc1a3 (Mus musculus (mouse))
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Synonyms: Gmt1, GLAST, B430115D02Rik, MGluT1, Eaat1
Chromosome: 15
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:99917
Gene Symbol: Cdh11 (Mus musculus (mouse))
Name: cadherin 11
Synonyms: OB-cadherin, osteoblast-cadherin, Cad11
Chromosome: 8
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:99217
Gene Symbol: Asna1 (Mus musculus (mouse))
Name: arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Synonyms: 1810048H22Rik, ArsA
Chromosome: 8
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:1928379
Gene Symbol: Myo1e (Mus musculus (mouse))
Name: myosin IE
Synonyms: 2310020N23Rik, 9130023P14Rik
Chromosome: 9
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:106621
Gene Symbol: Dop1b (Mus musculus (mouse))
Name: DOP1 leucine zipper like protein B
Synonyms: Dopey2, 0610038M01Rik, 2610510B01Rik
Chromosome: 16
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:1917278
Gene Symbol: Fryl (Mus musculus (mouse))
Name: FRY like transcription coactivator
Synonyms: 2510002A14Rik, 2310004H21Rik, 9030227G01Rik
Chromosome: 5
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:1919563
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 15,805,946 bp
  • T to C, chromosome 1 at 86,854,467 bp
  • A to G, chromosome 1 at 91,357,914 bp
  • T to A, chromosome 1 at 181,054,931 bp
  • T to C, chromosome 1 at 186,968,089 bp
  • T to C, chromosome 1 at 191,021,156 bp
  • T to C, chromosome 2 at 18,734,105 bp
  • C to T, chromosome 2 at 30,256,649 bp
  • T to C, chromosome 2 at 41,341,849 bp
  • A to T, chromosome 2 at 59,912,723 bp
  • A to T, chromosome 2 at 60,431,973 bp
  • C to T, chromosome 2 at 84,981,998 bp
  • T to A, chromosome 2 at 88,831,405 bp
  • T to A, chromosome 2 at 112,647,016 bp
  • A to G, chromosome 2 at 118,279,432 bp
  • T to C, chromosome 3 at 20,030,527 bp
  • G to T, chromosome 3 at 88,451,361 bp
  • G to A, chromosome 4 at 58,844,165 bp
  • G to A, chromosome 4 at 112,021,456 bp
  • T to C, chromosome 4 at 117,000,685 bp
  • T to C, chromosome 4 at 119,195,863 bp
  • T to C, chromosome 4 at 134,202,358 bp
  • T to A, chromosome 4 at 143,949,883 bp
  • T to C, chromosome 4 at 155,442,081 bp
  • A to G, chromosome 5 at 5,604,306 bp
  • A to T, chromosome 5 at 67,339,975 bp
  • T to A, chromosome 5 at 73,022,122 bp
  • T to A, chromosome 5 at 107,359,224 bp
  • A to C, chromosome 5 at 109,192,077 bp
  • A to G, chromosome 5 at 114,766,450 bp
  • A to G, chromosome 5 at 120,120,242 bp
  • A to G, chromosome 5 at 137,485,185 bp
  • T to C, chromosome 5 at 145,451,857 bp
  • T to A, chromosome 6 at 86,020,642 bp
  • T to A, chromosome 7 at 13,052,731 bp
  • T to C, chromosome 7 at 24,292,289 bp
  • T to C, chromosome 7 at 30,659,400 bp
  • T to A, chromosome 7 at 62,380,594 bp
  • T to A, chromosome 7 at 102,984,271 bp
  • T to C, chromosome 7 at 103,219,760 bp
  • T to C, chromosome 7 at 107,106,436 bp
  • GTCCAGGCATCTC to GTC, chromosome 7 at 142,512,627 bp
  • C to G, chromosome 8 at 24,650,877 bp
  • A to G, chromosome 8 at 33,571,274 bp
  • A to G, chromosome 8 at 69,663,917 bp
  • T to A, chromosome 8 at 83,677,963 bp
  • A to T, chromosome 8 at 85,019,774 bp
  • A to G, chromosome 8 at 88,745,312 bp
  • A to T, chromosome 8 at 93,534,577 bp
  • A to G, chromosome 8 at 102,679,772 bp
  • A to T, chromosome 8 at 104,498,100 bp
  • A to C, chromosome 8 at 104,617,802 bp
  • A to G, chromosome 9 at 19,645,236 bp
  • A to T, chromosome 9 at 30,429,000 bp
  • A to G, chromosome 9 at 35,268,014 bp
  • A to T, chromosome 9 at 44,818,450 bp
  • A to G, chromosome 9 at 48,985,503 bp
  • T to A, chromosome 9 at 69,464,480 bp
  • A to T, chromosome 9 at 70,368,687 bp
  • T to C, chromosome 9 at 70,378,715 bp
  • T to C, chromosome 9 at 75,289,055 bp
  • T to G, chromosome 9 at 78,065,044 bp
  • G to T, chromosome 9 at 86,521,365 bp
  • A to T, chromosome 9 at 100,786,687 bp
  • A to G, chromosome 9 at 101,145,481 bp
  • C to G, chromosome 9 at 108,575,355 bp
  • G to A, chromosome 10 at 116,347,053 bp
  • G to C, chromosome 10 at 130,425,574 bp
  • G to A, chromosome 11 at 7,139,142 bp
  • T to A, chromosome 11 at 21,148,110 bp
  • G to T, chromosome 11 at 55,228,338 bp
  • T to A, chromosome 11 at 58,625,493 bp
  • G to A, chromosome 11 at 61,378,007 bp
  • G to A, chromosome 11 at 62,267,473 bp
  • A to T, chromosome 11 at 67,194,625 bp
  • A to T, chromosome 11 at 67,361,289 bp
  • C to T, chromosome 11 at 69,403,592 bp
  • A to G, chromosome 11 at 72,437,541 bp
  • A to G, chromosome 11 at 73,425,362 bp
  • T to C, chromosome 11 at 105,100,025 bp
  • A to G, chromosome 11 at 109,583,190 bp
  • T to A, chromosome 11 at 116,601,148 bp
  • A to T, chromosome 12 at 88,321,421 bp
  • A to T, chromosome 12 at 114,322,814 bp
  • A to T, chromosome 13 at 13,964,791 bp
  • T to C, chromosome 13 at 92,504,477 bp
  • T to A, chromosome 13 at 98,637,038 bp
  • G to A, chromosome 14 at 21,039,149 bp
  • C to T, chromosome 14 at 50,810,086 bp
  • T to A, chromosome 14 at 55,943,734 bp
  • A to G, chromosome 15 at 8,645,669 bp
  • C to T, chromosome 15 at 47,838,579 bp
  • A to G, chromosome 16 at 93,769,435 bp
  • A to T, chromosome 17 at 17,568,399 bp
  • T to C, chromosome 17 at 20,224,578 bp
  • A to G, chromosome 17 at 20,375,287 bp
  • G to T, chromosome 17 at 33,067,624 bp
  • A to G, chromosome 17 at 34,314,392 bp
  • A to G, chromosome 17 at 36,813,907 bp
  • A to C, chromosome 17 at 74,245,054 bp
  • G to A, chromosome 17 at 87,422,784 bp
  • T to A, chromosome 17 at 94,875,824 bp
  • A to G, chromosome 18 at 15,151,309 bp
  • T to C, chromosome 18 at 63,118,935 bp
  • A to G, chromosome 19 at 8,793,418 bp
  • T to C, chromosome Y at 1,266,389 bp
Genotype Determination
ES Cell Line
N/A
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
MeSH Terms
    Strain Development
    C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
    Suggested Control Mice
    Wild-type littermates or C57BL/6J mice
    Primary Reference
    MUTAGENETIX record for R2029 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

    Colony and Husbandry Information

    Colony Surveillance Program and Current Health Reports

    Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
    Coat Color
    Black
    MMRRC Breeding System
    Random intra-strain mating
    Breeding Scheme(s)
    When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
    Overall Breeding Performance
    Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
    Average litter size
    Undetermined
    Recommended wean age
    3 weeks

    Order Request Information

    Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

    Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

    The donor or their institution limits the distribution to non-profit institutions only.

    Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

    Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
    MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
    040036-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.

    Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

    1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

    2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

    3 An aliquot contains a sufficient number of embryos (in one or more vials and based on the transfer success rate of the MMRRC facility) to transfer to at least two recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

    To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.