Strain Name:
C57BL/6J-MtgxR2211Btlr/Mmmh
Stock Number:
040213-MU
Citation ID:
RRID:MMRRC_040213-MU
Other Names:
R2211 (G1), C57BL/6J-MtgxR2211Btlr
Major Collection:

Gene Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: nmf261, Spnb4, neuroaxonal dystrophy, 1700022P15Rik, SpbIV, ROSA62, dyn, 5830426A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80297
Homologene: 11879
Sphk2
Name: sphingosine kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56632
Homologene: 32456
Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: Brg1, b2b508.1Clo, SNF2beta, SW1/SNF, b2b692Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20586
Homologene: 135927
Notch3
Name: notch 3
Synonyms: hpbk, N3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Ltbp3
Name: latent transforming growth factor beta binding protein 3
Synonyms: Ltbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16998
VEGA: 19
HGNC: HGNC:6716
Homologene: 7405
Adcy10
Name: adenylate cyclase 10
Synonyms: 4930431D04Rik, soluble adenylyl cyclase, Sacy, sAC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271639
Homologene: 10188
Plekha7
Name: pleckstrin homology domain containing, family A member 7
Synonyms: A430081P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233765
Homologene: 52172
Rarg
Name: retinoic acid receptor, gamma
Synonyms: RAR gamma 2, RARgamma2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19411
HGNC: HGNC:9866
Homologene: 20263
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, A930013E17Rik, Zap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Hap1
Name: huntingtin-associated protein 1
Synonyms: HAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15114
HGNC: HGNC:4812
Homologene: 2935
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Etaa1
Name: Ewing tumor-associated antigen 1
Synonyms: 5730466H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68145
Homologene: 10369
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: ARHGAP10, 5530401C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71435
Homologene: 10822
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Dsk9, Mhdadsk9, Nf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Trmt13
Name: tRNA methyltransferase 13
Synonyms: A930028L21Rik, 4631408H19Rik, Ccdc76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229780
Homologene: 6875
Cdc42bpb
Name: CDC42 binding protein kinase beta
Synonyms: DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217866
VEGA: 12
HGNC: HGNC:1738
Homologene: 55945
Rcc2
Name: regulator of chromosome condensation 2
Synonyms: Td60, 2610529N02Rik, 2610510H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108911
Homologene: 10282
Ints4
Name: integrator complex subunit 4
Synonyms: 2610034N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101861
Homologene: 69427
Rsf1
Name: remodeling and spacing factor 1
Synonyms: C030033M12Rik, 4832420A03Rik, p325, Hbxap, XAP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233532
Homologene: 41142
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: PEPP2, Gt(Ayu21)9Imeg, Ayu21-9, Tg(AMH-cre)1Flor, 2810431N21Rik, AMH-Cre
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109135
Homologene: 10377
Nbr1
Name: NBR1, autophagy cargo receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17966
HGNC: HGNC:6746
Homologene: 7438
Id4
Name: inhibitor of DNA binding 4
Synonyms: Id4, Idb4, bHLHb27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15904
VEGA: 13
HGNC: HGNC:5363
Homologene: 1186
Cebpa
Name: CCAAT/enhancer binding protein (C/EBP), alpha
Synonyms: C/ebpalpha, Cebp, C/EBP alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12606
HGNC: HGNC:1833
Homologene: 3211
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7a, Dnahc7, LOC381341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Fabp3
Name: fatty acid binding protein 3, muscle and heart
Synonyms: Fabph1, Fabph4, Mdgi, H-FABP, Fabph-1, Fabph-4, Fabp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14077
HGNC: HGNC:3557
Homologene: 68379
Lrrtm4
Name: leucine rich repeat transmembrane neuronal 4
Synonyms: 7530419J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243499
Homologene: 11807
Emc10
Name: ER membrane protein complex subunit 10
Synonyms: 5430410O10Rik, Mirta22, 2310044H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69683
Homologene: 18036
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Dtgn3, Adam27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Cpa4
Name: carboxypeptidase A4
Synonyms: 1110019K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71791
Homologene: 56753
Oit3
Name: oncoprotein induced transcript 3
Synonyms: EF-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18302
Homologene: 7870
Dnajc1
Name: DnaJ heat shock protein family (Hsp40) member C1
Synonyms: MTJ1, 4733401K02Rik, Dnajl1, D230036H06Rik, ERdj1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13418
Homologene: 7293
Edem3
Name: ER degradation enhancer, mannosidase alpha-like 3
Synonyms: 2310050N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66967
Homologene: 11866
Zfp524
Name: zinc finger protein 524
Synonyms: 0610012F07Rik, 2300009P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66056
Homologene: 11912
Nupl1
Name: nucleoporin like 1
Synonyms: 1700017F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71844
VEGA: 14
Homologene: 40924
Gzf1
Name: GDNF-inducible zinc finger protein 1
Synonyms: Zfp336, 8430437G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74533
Homologene: 11200
Mnd1
Name: meiotic nuclear divisions 1
Synonyms: 2610034E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76915
Homologene: 5890
AU041133
Name: expressed sequence AU041133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216177
Homologene: 87560
Ppwd1
Name: peptidylprolyl isomerase domain and WD repeat containing 1
Synonyms: A330090G21Rik, 4632422M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238831
VEGA: 13
Homologene: 9099
Slc35f5
Name: solute carrier family 35, member F5
Synonyms: 1300003P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74150
Homologene: 5745
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: nmf252, ahl, nmf181, USH1D, nmf112, bob, sals, mdfw, 4930542A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Sec31b
Name: Sec31 homolog B (S. cerevisiae)
Synonyms: Sec31l2, LOC240667
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240667
Homologene: 56708
Sema6b
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Synonyms: Sema, VIb, Seman, semaZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20359
VEGA: 17
Homologene: 8428
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Ogfod2
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 2
Synonyms: 5730405M13Rik, 1300006G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66627
Homologene: 32588
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Plcb2
Name: phospholipase C, beta 2
Synonyms: B230205M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18796
HGNC: HGNC:9055
Homologene: 20957
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: Dcdc3, Orp1, Rp1h, mG145, oxygen-regulated protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19888
Homologene: 4564
Naglu
Name: alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27419
HGNC: HGNC:7632
Homologene: 222
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: Arhgap13, 4930572H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 117600
Homologene: 56898
4932441B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Rnpepl1
Name: arginyl aminopeptidase (aminopeptidase B)-like 1
Synonyms: 1110014H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108657
Homologene: 36367
Spsb3
Name: splA/ryanodine receptor domain and SOCS box containing 3
Synonyms: 3300001M01Rik, Tce1, SSB3, 2310012N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 79043
Homologene: 12322
Fbxw10
Name: F-box and WD-40 domain protein 10
Synonyms: SM25H2, Fbw10, SM2SH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 213980
Homologene: 32757
Arfgef3
Name: ARFGEF family member 3
Synonyms: BIG3, B930094H20Rik, D10Bwg1379e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Fam149a
Name: family with sequence similarity 149, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212326
Homologene: 27540
Olfr804
Name: olfactory receptor 804
Synonyms: MOR110-7, GA_x6K02T2PULF-11383575-11384519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258068
Homologene: 133581
Hic1
Name: hypermethylated in cancer 1
Synonyms: HIC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15248
HGNC: HGNC:4909
Homologene: 4740
Il3ra
Name: interleukin 3 receptor, alpha chain
Synonyms: SUT-1, CD123, IL-3 receptor alpha chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16188
VEGA: 14
HGNC: HGNC:6012
Homologene: 48088
Olfr1497
Name: olfactory receptor 1497
Synonyms: MOR212-1, GA_x6K02T2RE5P-4127765-4126821
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258736
Homologene: 17373
Lmln
Name: leishmanolysin-like (metallopeptidase M8 family)
Synonyms: 5330415H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239833
Homologene: 13198
Zfp777
Name: zinc finger protein 777
Synonyms: 2500002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72306
Homologene: 56721
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Cfap221
Name: cilia and flagella associated protein 221
Synonyms: Gm101, Pcdp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226356
Homologene: 88578
Olfr787
Name: olfactory receptor 787
Synonyms: MOR111-10, GA_x6K02T2PULF-11141498-11142436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258069
Homologene: 105326
A430078G23Rik
Name: RIKEN cDNA A430078G23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Trim43b
Name: tripartite motif-containing 43B
Synonyms: Gm8269
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 666747
Homologene: 105432
Rsph3b
Name: radial spoke 3B homolog (Chlamydomonas)
Synonyms: Rshl2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100037282
VEGA: 17
Homologene: 12043
Dpysl5
Name: dihydropyrimidinase-like 5
Synonyms: CRAM, CRMP-5, Crmp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 65254
Homologene: 41347
FP885536.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
AC148991.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Fam98a
Name: family with sequence similarity 98, member A
Synonyms: 2810405J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72722
Homologene: 41042
Nol7
Name: nucleolar protein 7
Synonyms: 5730556I21Rik, RARG-1, NOP27, 2210008F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70078
VEGA: 13
Homologene: 49451
Cnn1
Name: calponin 1
Synonyms: CnnI, calponin h1, CN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12797
VEGA: 9
HGNC: HGNC:2155
Homologene: 995
Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Synonyms: A830037N07Rik, Pgc1, Pgc-1alphaa, Pgc-1alpha, Gm11133, PPAR Gamma Coactivator-1, Pgco1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19017
HGNC: HGNC:9237
Homologene: 7485
Olfr1079
Name: olfactory receptor 1079
Synonyms: GA_x6K02T2Q125-48024195-48023254, MOR189-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258402
Homologene: 74090
Mpp5
Name: membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
Synonyms: 3830420B02Rik, Pals1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56217
VEGA: 12
Homologene: 9512
Ddx51
Name: DEAD box helicase 51
Synonyms: 2310061O04Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69663
Homologene: 6850
Pcbp4
Name: poly(rC) binding protein 4
Synonyms: AlphaCP-4, 1200003L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 59092
HGNC: HGNC:8652
Homologene: 56926
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 4,348,139 bp
  • T to C, chromosome 1 at 53,479,773 bp
  • T to A, chromosome 1 at 63,573,129 bp
  • C to T, chromosome 1 at 92,916,380 bp
  • A to G, chromosome 1 at 119,949,665 bp
  • A to T, chromosome 1 at 125,579,264 bp
  • A to G, chromosome 1 at 151,804,702 bp
  • A to G, chromosome 1 at 158,657,306 bp
  • A to T, chromosome 1 at 165,518,212 bp
  • G to T, chromosome 2 at 18,392,475 bp
  • A to T, chromosome 2 at 20,881,640 bp
  • T to C, chromosome 2 at 86,538,513 bp
  • T to C, chromosome 2 at 118,723,534 bp
  • C to T, chromosome 2 at 148,684,950 bp
  • A to G, chromosome 3 at 38,891,527 bp
  • C to A, chromosome 3 at 84,134,109 bp
  • A to G, chromosome 3 at 116,594,754 bp
  • C to T, chromosome 4 at 130,312,387 bp
  • T to C, chromosome 4 at 140,708,051 bp
  • T to C, chromosome 4 at 156,333,492 bp
  • G to A, chromosome 5 at 30,791,597 bp
  • A to C, chromosome 5 at 51,474,259 bp
  • T to A, chromosome 5 at 110,655,768 bp
  • C to A, chromosome 5 at 124,112,780 bp
  • A to G, chromosome 6 at 18,214,280 bp
  • A to G, chromosome 6 at 30,583,650 bp
  • T to C, chromosome 6 at 48,043,885 bp
  • A to G, chromosome 6 at 80,022,640 bp
  • G to A, chromosome 6 at 140,525,861 bp
  • T to C, chromosome 7 at 5,017,919 bp
  • T to C, chromosome 7 at 27,367,609 bp
  • T to C, chromosome 7 at 35,120,466 bp
  • G to A, chromosome 7 at 44,493,192 bp
  • G to A, chromosome 7 at 45,712,045 bp
  • T to C, chromosome 7 at 97,509,750 bp
  • ATGGCG to ATGGCGAGGGTGGCG, chromosome 7 at 97,579,904 bp
  • A to G, chromosome 7 at 116,137,387 bp
  • T to C, chromosome 8 at 3,387,680 bp
  • A to G, chromosome 8 at 24,628,155 bp
  • G to A, chromosome 8 at 45,341,009 bp
  • A to G, chromosome 9 at 21,686,029 bp
  • G to T, chromosome 9 at 22,107,904 bp
  • T to A, chromosome 9 at 89,085,249 bp
  • C to A, chromosome 9 at 106,460,734 bp
  • A to T, chromosome 10 at 18,592,245 bp
  • T to C, chromosome 10 at 59,428,070 bp
  • T to C, chromosome 10 at 60,466,004 bp
  • G to A, chromosome 10 at 82,150,921 bp
  • A to G, chromosome 10 at 121,853,740 bp
  • A to T, chromosome 10 at 129,462,940 bp
  • A to G, chromosome 10 at 129,705,451 bp
  • G to A, chromosome 11 at 17,952,686 bp
  • A to G, chromosome 11 at 62,867,535 bp
  • T to A, chromosome 11 at 75,169,384 bp
  • T to C, chromosome 11 at 79,444,064 bp
  • G to A, chromosome 11 at 100,354,724 bp
  • A to G, chromosome 11 at 101,072,206 bp
  • T to C, chromosome 11 at 101,567,264 bp
  • A to T, chromosome 12 at 78,797,248 bp
  • A to T, chromosome 12 at 85,044,378 bp
  • A to G, chromosome 12 at 111,301,854 bp
  • A to G, chromosome 13 at 43,401,292 bp
  • T to A, chromosome 13 at 48,261,802 bp
  • T to C, chromosome 13 at 65,035,939 bp
  • G to A, chromosome 13 at 104,207,142 bp
  • T to C, chromosome 14 at 14,355,029 bp
  • A to G, chromosome 14 at 60,232,640 bp
  • T to C, chromosome 15 at 102,239,524 bp
  • A to G, chromosome 16 at 33,109,778 bp
  • C to A, chromosome 17 at 3,414,918 bp
  • T to C, chromosome 17 at 6,941,740 bp
  • T to C, chromosome 17 at 24,890,937 bp
  • T to A, chromosome 17 at 32,147,978 bp
  • T to A, chromosome 17 at 56,124,741 bp
  • A to G, chromosome 17 at 75,538,945 bp
  • T to C, chromosome 19 at 5,753,962 bp
  • C to A, chromosome 19 at 10,997,305 bp
  • T to A, chromosome 19 at 13,795,369 bp
  • A to T, chromosome 19 at 24,378,850 bp
  • A to T, chromosome 19 at 44,523,150 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2211 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040213-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.