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Strain Name:
C57BL/6J-MtgxR2239Btlr/Mmmh
Stock Number:
040239-MU
Citation ID:
RRID:MMRRC_040239-MU
Other Names:
R2239 (G1), C57BL/6J-MtgxR2239Btlr
Major Collection:

Strain Information

Ltbp3
Name: latent transforming growth factor beta binding protein 3
Synonyms: Ltbp2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16998
VEGA: 19
HGNC: HGNC:6716
Homologene: 7405
Eomes
Name: eomesodermin
Synonyms: Tbr2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13813
HGNC: HGNC:3372
Homologene: 3971
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: 2510010B09Rik, D10Ertd17e, Cxxc6, BB001228
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52463
Homologene: 12735
Map7
Name: microtubule-associated protein 7
Synonyms: E-MAP-115, mste, ste, mshi, Mtap7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17761
VEGA: 10
HGNC: HGNC:6869
Homologene: 20851
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Rgs3
Name: regulator of G-protein signaling 3
Synonyms: 4930506N09Rik, PDZ-RGS3, C2pa, RGS3S, C2PA-RGS3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50780
HGNC: HGNC:9999
Homologene: 32440
Cilk1
Name: ciliogenesis associated kinase 1
Synonyms: 2210420N10Rik, Ick
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56542
Homologene: 69218
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208628
Homologene: 32227
Kdm6a
Name: lysine (K)-specific demethylase 6A
Synonyms: Utx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 22289
Homologene: 7586
Ago3
Name: argonaute RISC catalytic subunit 3
Synonyms: argonaute 3, eIF2C3, C130014L07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 214150
Homologene: 49799
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Cux1
Name: cut-like homeobox 1
Synonyms: Cux, CDP, Cux-1, Cutl1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13047
HGNC: HGNC:2557
Lgr4
Name: leucine-rich repeat-containing G protein-coupled receptor 4
Synonyms: A930009A08Rik, Gpr48, A330106J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107515
Homologene: 10226
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, D14Ertd453e, Fndc3, sys
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: Nrf2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18024
HGNC: HGNC:7782
Homologene: 2412
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Phka2
Name: phosphorylase kinase alpha 2
Synonyms: k, Phk, 6330505C01Rik
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 110094
HGNC: HGNC:8926
Homologene: 246
Cog8
Name: component of oligomeric golgi complex 8
Synonyms: C87832
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 97484
Homologene: 13018
Arl10
Name: ADP-ribosylation factor-like 10
Synonyms: ARL10, Arm1, Arl10a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56795
Homologene: 10550
Cep128
Name: centrosomal protein 128
Synonyms: 5430424K18Rik, 4930534B04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75216
Homologene: 35315
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: NMHC II-C, 2400004E04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71960
Homologene: 23480
Kcnh5
Name: potassium voltage-gated channel, subfamily H (eag-related), member 5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238271
VEGA: 12
HGNC: HGNC:6254
Homologene: 15858
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC224088, LOC224087, LOC385637
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224088
Homologene: 23455
Map3k1
Name: mitogen-activated protein kinase kinase kinase 1
Synonyms: MEKK1, Mekk
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26401
HGNC: HGNC:6848
Homologene: 8056
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101471
Homologene: 16377
Dars2
Name: aspartyl-tRNA synthetase 2 (mitochondrial)
Synonyms: 5830468K18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226539
Homologene: 7093
Ap5z1
Name: adaptor-related protein complex 5, zeta 1 subunit
Synonyms: C330006K01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231855
Homologene: 18213
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
P4hb
Name: prolyl 4-hydroxylase, beta polypeptide
Synonyms: ERp59, protein disulfide isomerase, Thbp, Pdia1, PDI
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18453
HGNC: HGNC:8548
Homologene: 55495
Cdc37
Name: cell division cycle 37
Synonyms: p50Cdc37
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12539
VEGA: 9
HGNC: HGNC:1735
Homologene: 38268
Ccdc47
Name: coiled-coil domain containing 47
Synonyms: asp4, 2610204L23Rik, calumin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67163
Homologene: 41351
Gca
Name: grancalcin
Synonyms: 5133401E04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227960
Homologene: 22702
Ttc7b
Name: tetratricopeptide repeat domain 7B
Synonyms: Ttc7l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104718
VEGA: 12
Homologene: 14675
Exoc1
Name: exocyst complex component 1
Synonyms: Sec3p, SEC3, A730011E05Rik, 2810407P21Rik, Sec3l1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69940
Homologene: 41241
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: CD140a, Pdgfr-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Pde4a
Name: phosphodiesterase 4A, cAMP specific
Synonyms: dunce, Dpde2, D9Ertd60e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18577
HGNC: HGNC:8780
Homologene: 4520
Col24a1
Name: collagen, type XXIV, alpha 1
Synonyms: 5430404K19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71355
Homologene: 65061
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75288
Homologene: 45939
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: basilin, FOAP-10
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: GlcT-1, Epcs21, Ugcgl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22234
Homologene: 37763
Cdh5
Name: cadherin 5
Synonyms: VE-cadherin, 7B4/cadherin-5, VEC, CD144, VE-Cad, VECD, VEcad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242627
Homologene: 135888
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Camk2g
Name: calcium/calmodulin-dependent protein kinase II gamma
Synonyms: CaMK II, Ca2+/calmodulin-dependent protein kinase II, Camkg, 5930429P18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12325
VEGA: 14
HGNC: HGNC:1463
Homologene: 15596
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218214
Homologene: 14695
Or5ac23
Name: olfactory receptor family 5 subfamily AC member 23
Synonyms: GA_x54KRFPKG5P-55543875-55542958, MOR182-11P, Olfr205
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 257881
Homologene: 79469
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94229
Homologene: 23340
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227058
Homologene: 41287
Papolg
Name: poly(A) polymerase gamma
Synonyms: 9630006B20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216578
Homologene: 56959
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: LOC380973, 1700030F18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72277
Stac
Name: src homology three (SH3) and cysteine rich domain
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20840
Homologene: 2371
Smr2l
Name: submaxillary gland androgen regulated protein 2 like
Synonyms: Gm7714
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665615
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: SAPLT, 1700042F02Rik, 1700056N23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Or5l13
Name: olfactory receptor family 5 subfamily L member 13
Synonyms: GA_x6K02T2Q125-49433499-49432537, MOR174-3, Olfr1156
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258814
HGNC: HGNC:8351
Homologene: 72031
Abcc1
Name: ATP-binding cassette, sub-family C member 1
Synonyms: MRP, Mdrap, Mrp1, Abcc1b, Abcc1a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Pcgf5
Name: polycomb group ring finger 5
Synonyms: 5830443C21Rik, 9530023M17Rik, 1110054A01Rik, 0610009F02Rik, 5830406C17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76073
VEGA: 19
Homologene: 12632
Tnfsf11
Name: tumor necrosis factor (ligand) superfamily, member 11
Synonyms: RANKL, OPGL, ODF, Ly109l, Trance, osteoclast differentiation factor, OPGL
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21943
VEGA: 14
Homologene: 2744
Cnnm4
Name: cyclin M4
Synonyms: Acdp4, 5430430O18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 94220
HGNC: HGNC:105
Homologene: 75662
Ift88
Name: intraflagellar transport 88
Synonyms: Tg737, polaris, Oak Ridge polycystic kidneys, orpk, IFT88, fxo, TgN737Rpw, Tg737Rpw, Ttc10
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21821
Homologene: 4761
Slc16a8
Name: solute carrier family 16 (monocarboxylic acid transporters), member 8
Synonyms: proton-coupled monocarboxylate transporter 3, Mct3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 57274
Homologene: 75006
Men1
Name: multiple endocrine neoplasia 1
Synonyms: menin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 17283
HGNC: HGNC:7010
Homologene: 7418
Zpld2
Name: zona pellucida like domain containing 2
Synonyms: Gm7534
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 665186
Homologene: 104039
Or10v5
Name: olfactory receptor family 10 subfamily V member 5
Synonyms: GA_x6K02T2RE5P-2172809-2171862, MOR266-2, Olfr1417
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258938
Homologene: 27304
Fam98a
Name: family with sequence similarity 98, member A
Synonyms: 2810405J04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72722
Homologene: 41042
Or5b109
Name: olfactory receptor family 5 subfamily B member 109
Synonyms: GA_x6K02T2RE5P-3560863-3561795, MOR202-29P, Olfr1463
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258120
HGNC: HGNC:8324
Homologene: 133886
Spata4
Name: spermatogenesis associated 4
Synonyms: SRG2, TSARG2, 1700001N01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69281
Homologene: 15868
Cd200r4
Name: CD200 receptor 4
Synonyms: MCD200RLa, F630107N04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239849
Homologene: 45557
Sult2a1
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Synonyms: mSTa1, Std, Sth1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20859
Homologene: 37741
Morn4
Name: MORN repeat containing 4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226123
VEGA: 19
Homologene: 16635
Trmt5
Name: TRM5 tRNA methyltransferase 5
Synonyms: 2610027O18Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76357
VEGA: 12
Homologene: 6096
Hsd17b1
Name: hydroxysteroid (17-beta) dehydrogenase 1
Synonyms: 17beta-HSD, Hsd17ba
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15485
HGNC: HGNC:5210
Homologene: 37303
Arhgap36
Name: Rho GTPase activating protein 36
Synonyms: 1100001E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 75404
Homologene: 17012
Htatsf1
Name: HIV TAT specific factor 1
Synonyms: 1600023H17Rik, 2700077B20Rik, TAT-SF1, 2600017A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 72459
HGNC: HGNC:5276
Homologene: 40950
Spin2c
Name: spindlin family, member 2C
Synonyms: Spin2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 278240
Homologene: 10370
Or2aa1
Name: olfactory receptor family 2 subfamily AA member 1
Synonyms: GA_x6K02T000SA-78-1037, MOR256-30, Olfr223
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258421
Homologene: 73917
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 36,505,678 bp
  • C to A, chromosome 1 at 46,201,184 bp
  • T to C, chromosome 1 at 132,583,022 bp
  • T to A, chromosome 1 at 139,456,846 bp
  • T to C, chromosome 1 at 161,063,282 bp
  • C to A, chromosome 1 at 188,576,214 bp
  • T to A, chromosome 2 at 62,268,646 bp
  • T to A, chromosome 2 at 62,690,377 bp
  • G to A, chromosome 2 at 75,676,554 bp
  • T to C, chromosome 2 at 87,949,397 bp
  • T to C, chromosome 2 at 110,012,393 bp
  • T to A, chromosome 3 at 145,358,508 bp
  • C to T, chromosome 4 at 59,207,798 bp
  • A to T, chromosome 4 at 62,625,887 bp
  • G to A, chromosome 4 at 113,546,536 bp
  • G to A, chromosome 4 at 126,368,522 bp
  • A to C, chromosome 4 at 134,202,205 bp
  • A to G, chromosome 5 at 73,108,547 bp
  • T to A, chromosome 5 at 75,181,508 bp
  • T to C, chromosome 5 at 76,559,710 bp
  • T to G, chromosome 5 at 88,282,554 bp
  • T to C, chromosome 5 at 123,803,670 bp
  • A to G, chromosome 5 at 136,408,041 bp
  • G to A, chromosome 5 at 137,457,837 bp
  • G to A, chromosome 5 at 142,474,865 bp
  • A to G, chromosome 7 at 5,097,602 bp
  • G to A, chromosome 7 at 13,801,372 bp
  • A to T, chromosome 7 at 44,665,183 bp
  • A to G, chromosome 7 at 141,237,692 bp
  • T to C, chromosome 8 at 24,646,287 bp
  • A to C, chromosome 8 at 54,602,629 bp
  • T to C, chromosome 8 at 95,769,521 bp
  • C to A, chromosome 8 at 104,125,672 bp
  • C to A, chromosome 8 at 107,056,361 bp
  • G to A, chromosome 9 at 21,142,533 bp
  • G to A, chromosome 9 at 21,211,268 bp
  • T to C, chromosome 9 at 78,155,336 bp
  • G to A, chromosome 9 at 111,690,122 bp
  • A to G, chromosome 9 at 118,482,291 bp
  • C to T, chromosome 9 at 122,771,147 bp
  • A to T, chromosome 10 at 20,278,282 bp
  • T to C, chromosome 10 at 62,879,734 bp
  • A to G, chromosome 10 at 80,530,988 bp
  • A to G, chromosome 11 at 23,876,378 bp
  • A to G, chromosome 11 at 59,589,271 bp
  • A to T, chromosome 11 at 101,078,463 bp
  • G to T, chromosome 11 at 106,202,134 bp
  • A to G, chromosome 11 at 120,563,282 bp
  • C to A, chromosome 12 at 10,375,558 bp
  • A to G, chromosome 12 at 73,285,114 bp
  • T to A, chromosome 12 at 75,007,719 bp
  • T to C, chromosome 12 at 91,347,567 bp
  • A to G, chromosome 12 at 100,355,001 bp
  • T to A, chromosome 13 at 47,073,755 bp
  • G to T, chromosome 13 at 54,575,149 bp
  • A to C, chromosome 13 at 111,748,944 bp
  • A to G, chromosome 14 at 20,739,387 bp
  • A to G, chromosome 14 at 49,306,203 bp
  • A to G, chromosome 14 at 57,455,504 bp
  • A to T, chromosome 14 at 72,574,339 bp
  • A to T, chromosome 14 at 78,299,981 bp
  • T to C, chromosome 15 at 79,252,947 bp
  • C to T, chromosome 15 at 99,954,864 bp
  • T to C, chromosome 16 at 14,443,339 bp
  • T to G, chromosome 16 at 30,338,422 bp
  • T to A, chromosome 16 at 44,820,897 bp
  • T to A, chromosome 16 at 59,329,375 bp
  • T to A, chromosome 17 at 71,310,224 bp
  • A to C, chromosome 17 at 75,547,772 bp
  • C to A, chromosome 19 at 5,751,523 bp
  • T to A, chromosome 19 at 6,337,590 bp
  • T to C, chromosome 19 at 11,828,450 bp
  • T to C, chromosome 19 at 13,234,721 bp
  • A to T, chromosome 19 at 36,437,354 bp
  • A to G, chromosome 19 at 42,078,032 bp
  • T to C, chromosome 19 at 46,163,618 bp
  • T to C, chromosome X at 18,199,237 bp
  • G to T, chromosome X at 49,493,405 bp
  • G to T, chromosome X at 57,066,504 bp
  • A to G, chromosome X at 153,833,676 bp
  • A to G, chromosome X at 160,541,412 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2239 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040239-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.