Strain Name:
C57BL/6J-MtgxR2259Btlr/Mmmh
Stock Number:
040259-MU
Citation ID:
RRID:MMRRC_040259-MU
Other Names:
R2259 (G1), C57BL/6J-MtgxR2259Btlr
Major Collection:

Gene Information

Sod1
Name: superoxide dismutase 1, soluble
Synonyms: Cu/Zn-SOD, Ipo-1, Cu(2+)-Zn2+ superoxide dismutase, B430204E11Rik, Ipo1, SODC, Sod-1, CuZnSOD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20655
VEGA: 16
Homologene: 392
Npy2r
Name: neuropeptide Y receptor Y2
Synonyms: NPY-Y2 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18167
HGNC: HGNC:7957
Homologene: 701
Ift52
Name: intraflagellar transport 52
Synonyms: NGD5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 245866
Homologene: 9335
1190005I06Rik
Name: RIKEN cDNA 1190005I06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68918
Homologene: 18858
Dlg4
Name: discs large MAGUK scaffold protein 4
Synonyms: Dlgh4, SAP90A, SAP90, PSD-95, PSD95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13385
HGNC: HGNC:2903
Homologene: 1047
Trip10
Name: thyroid hormone receptor interactor 10
Synonyms: Cip4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106628
VEGA: 17
Homologene: 99728
E2f7
Name: E2F transcription factor 7
Synonyms: E2F7, A630014C11Rik, D10Ertd739e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52679
Homologene: 18685
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Psmd3
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Synonyms: AntP91a, Tstap91a, Psd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22123
HGNC: HGNC:9560
Homologene: 2102
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Fmn2
Name: formin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54418
Homologene: 137334
Tasp1
Name: taspase, threonine aspartase 1
Synonyms: 4930485D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75812
Homologene: 9795
Rab3gap2
Name: RAB3 GTPase activating protein subunit 2
Synonyms: 1110059F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98732
Homologene: 40842
Dctn1
Name: dynactin 1
Synonyms: Glued, p150glued, p150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Kdm2b
Name: lysine (K)-specific demethylase 2B
Synonyms: Fbxl10, Cxxc2, Jhdm1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 30841
Homologene: 13069
Gigyf1
Name: GRB10 interacting GYF protein 1
Synonyms: Perq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57330
HGNC: HGNC:9126
Homologene: 57145
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: Mll, trithorax Drosophila, HTRX1, Mll1, Cxxc7, ALL-1, All1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27103
Homologene: 40891
Zfp407
Name: zinc finger protein 407
Synonyms: 6430585N13Rik, LOC381139, LOC240469
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240476
Homologene: 86402
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Synonyms: 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18971
HGNC: HGNC:9175
Homologene: 2014
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: 2810487N22Rik, 4632407J06Rik, B130055D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Tmem242
Name: transmembrane protein 242
Synonyms: 5730437N04Rik, 2310046K16Rik, 1110008A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70544
Homologene: 44020
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 195018
Homologene: 9027
Trappc4
Name: trafficking protein particle complex 4
Synonyms: PTD009, HSPC172, 1500017G03Rik, Sbdn, TRS23, Sbd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 60409
VEGA: 9
Homologene: 105453
Xpo5
Name: exportin 5
Synonyms: 2700038C24Rik, 2410004H11Rik, Exp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72322
VEGA: 17
Homologene: 69316
Utp15
Name: UTP15 small subunit processome component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105372
VEGA: 13
Homologene: 6629
Galnt14
Name: polypeptide N-acetylgalactosaminyltransferase 14
Synonyms: 0610033M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71685
Homologene: 56997
Kif7
Name: kinesin family member 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16576
Homologene: 72555
Mettl7a1
Name: methyltransferase like 7A1
Synonyms: Mettl7a, 2210414H16Rik, 3300001H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70152
VEGA: 15
Homologene: 86842
Glb1
Name: galactosidase, beta 1
Synonyms: Bge, Bgl, Bgl-e, Bgl-t, Bgs, Bgl-s, C130097A14Rik, Bgt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12091
VEGA: 9
HGNC: HGNC:4298
Homologene: 47922
Jmjd6
Name: jumonji domain containing 6
Synonyms: PSR, 5730436I23Rik, PtdSerR, Ptdsr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107817
Homologene: 9046
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 84092
Homologene: 3782
Nptx1
Name: neuronal pentraxin 1
Synonyms: Np1, D11Bwg1004e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18164
HGNC: HGNC:7952
Homologene: 1891
Ttyh1
Name: tweety family member 1
Synonyms: 6330408P11Rik, tty, 4930459B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57776
Homologene: 10779
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: skrr, Ryr, calcium release channel isoform 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: steroid receptor coactivator-1, bHLHe74, SRC1, SRC-1, KAT13A, SRC-a/NCoA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Myo7a
Name: myosin VIIA
Synonyms: Hdb, USH1B, polka, nmf371, Myo7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17921
HGNC: HGNC:7606
Homologene: 219
Marveld2
Name: MARVEL (membrane-associating) domain containing 2
Synonyms: Tric, Mrvldc2, Tric-c, Tric-b, Tric-a, Tricellulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218518
VEGA: 13
Homologene: 27037
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Tmem138
Name: transmembrane protein 138
Synonyms: 1700113I01Rik, 2900055D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72982
VEGA: 19
Homologene: 9518
Unc13b
Name: unc-13 homolog B
Synonyms: Munc13-2, Unc13h2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22249
Homologene: 31376
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12815
HGNC: HGNC:2187
Homologene: 22547
Sema6b
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Synonyms: Seman, semaZ, Sema, VIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20359
VEGA: 17
Homologene: 8428
Insrr
Name: insulin receptor-related receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 23920
HGNC: HGNC:6093
Homologene: 56539
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Exoc7
Name: exocyst complex component 7
Synonyms: Exo70, 70kDa, sec70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53413
Homologene: 41019
Eln
Name: elastin
Synonyms: E030024M20Rik, tropoelastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13717
HGNC: HGNC:3327
Pear1
Name: platelet endothelial aggregation receptor 1
Synonyms: 3110045G13Rik, Jedi-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73182
Homologene: 12492
Trim30a
Name: tripartite motif-containing 30A
Synonyms: Trim30, Rpt1, Rpt-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20128
Homologene: 114426
Irf2
Name: interferon regulatory factor 2
Synonyms: 9830146E22Rik, Irf-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16363
HGNC: HGNC:6117
Homologene: 1659
Atp10b
Name: ATPase, class V, type 10B
Synonyms: 9030605H24Rik, 5930426O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319767
Homologene: 70969
Tshz2
Name: teashirt zinc finger family member 2
Synonyms: teashirt2, Sdccag33l, Zfp218, Tsh2, Mtsh2, 2900073F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228911
Homologene: 35258
Tmem30a
Name: transmembrane protein 30A
Synonyms: 2010200I23Rik, Cdc50a, D9Wsu20e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69981
Homologene: 110703
Dnaic2
Name: dynein, axonemal, intermediate chain 2
Synonyms: C030015H18Rik, b2b3405Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432611
Homologene: 11311
Ssc5d
Name: scavenger receptor cysteine rich family, 5 domains
Synonyms: s5d-srcrb, A430110N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269855
Homologene: 77555
Tmem132c
Name: transmembrane protein 132C
Synonyms: 4632425D07Rik, 2810482M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208213
Homologene: 76567
Fkbp6
Name: FK506 binding protein 6
Synonyms: D5Ertd724e, 1700008G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 94244
HGNC: HGNC:3722
Homologene: 2672
Flnc
Name: filamin C, gamma
Synonyms: 1110055E19Rik, Fln2, actin binding protein 280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228846
Homologene: 18598
Tcaf3
Name: TRPM8 channel-associated factor 3
Synonyms: Eapa2, Fam115e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 403088
Homologene: 74374
Npbwr1
Name: neuropeptides B/W receptor 1
Synonyms: Gpr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226304
HGNC: HGNC:4522
Homologene: 21096
Unc45b
Name: unc-45 myosin chaperone B
Synonyms: D230041A13Rik, Cmya4, UNC45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217012
Homologene: 14666
Olfr933
Name: olfactory receptor 933
Synonyms: GA_x6K02T2PVTD-32671531-32672457, MOR171-22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258433
VEGA: 9
HGNC: HGNC:8481
Homologene: 79676
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229927
Homologene: 135610
Ankrd13b
Name: ankyrin repeat domain 13b
Synonyms: B930093C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268445
Homologene: 27367
Vmn2r65
Name: vomeronasal 2, receptor 65
Synonyms: ENSMUSG00000070600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100009609
Plch1
Name: phospholipase C, eta 1
Synonyms: Plcl3, PLCeta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 269437
Homologene: 88833
Gba2
Name: glucosidase beta 2
Synonyms: bile acid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230101
Homologene: 10859
Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
Synonyms: testosterone 15alpha-hydroxylase, Cyp15a1, D7Ucla4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13086
Homologene: 85917
Repin1
Name: replication initiator 1
Synonyms: E430037F08Rik, AP4, Zfp464
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58887
Homologene: 22810
Olfr1350
Name: olfactory receptor 1350
Synonyms: MOR222-3, GA_x6K02T2QGBW-3300391-3301317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258384
Gm20518
Name: predicted gene 20518
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Insyn2a
Name: inhibitory synaptic factor 2A
Synonyms: Fam196a, B830028B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 627214
Homologene: 85469
Rpe65
Name: retinal pigment epithelium 65
Synonyms: rd12, Mord1, A930029L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19892
Homologene: 20108
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Trim35
Name: tripartite motif-containing 35
Synonyms: Hls5, 0710005M05Rik, Mair, A430106H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66854
Homologene: 134331
Spns2
Name: spinster homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216892
Homologene: 71040
Cnbd2
Name: cyclic nucleotide binding domain containing 2
Synonyms: 4921517L17Rik, 5430421B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70873
Homologene: 15440
Pde2a
Name: phosphodiesterase 2A, cGMP-stimulated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207728
HGNC: HGNC:8777
Homologene: 1952
Olfr295
Name: olfactory receptor 295
Synonyms: GA_x6K02T2NHDJ-9539243-9538314, MOR220-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258850
Homologene: 115526
Ager
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 11596
HGNC: HGNC:320
Homologene: 883
Josd2
Name: Josephin domain containing 2
Synonyms: 1110007C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66124
Homologene: 26696
Sephs2
Name: selenophosphate synthetase 2
Synonyms: Sps2, Ysg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20768
Homologene: 7550
Tnni3
Name: troponin I, cardiac 3
Synonyms: Tn1, cardiac troponin I, cTnI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21954
Homologene: 309
Fam187a
Name: family with sequence similarity 187, member A
Synonyms: 4933439F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66784
Homologene: 128440
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: 1110006M24Rik, PML, 0610012C17Rik, PLM, phospholemman
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Cflar
Name: CASP8 and FADD-like apoptosis regulator
Synonyms: A430105C05Rik, Cash, c-Flip, Flip, 2310024N18Rik, Casper
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12633
HGNC: HGNC:1876
Homologene: 7652
Gm11565
Name: predicted gene 11565
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 670550
Homologene: 134336
Tomm6
Name: translocase of outer mitochondrial membrane 6
Synonyms: 1110002E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66119
Homologene: 81910
Rnf208
Name: ring finger protein 208
Synonyms: 1110061N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68846
Homologene: 32752
Gpr160
Name: G protein-coupled receptor 160
Synonyms: 1700025D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71862
Homologene: 8659
Klhl38
Name: kelch-like 38
Synonyms: 8230402K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268807
Homologene: 18622
Eef2kmt
Name: eukaryotic elongation factor 2 lysine methyltransferase
Synonyms: Fam86, 5730409G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70511
Homologene: 45719
Pura
Name: purine rich element binding protein A
Synonyms: Pur-alpha, CAGER-1, ssCRE-BP, Pur alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19290
HGNC: HGNC:9701
Homologene: 4279
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 5,916,658 bp
  • A to G, chromosome 1 at 30,804,343 bp
  • C to T, chromosome 1 at 58,729,121 bp
  • T to A, chromosome 1 at 174,502,932 bp
  • T to A, chromosome 1 at 185,221,859 bp
  • G to A, chromosome 2 at 25,243,644 bp
  • A to C, chromosome 2 at 118,455,783 bp
  • A to G, chromosome 2 at 126,758,568 bp
  • A to T, chromosome 2 at 139,951,506 bp
  • T to A, chromosome 2 at 156,335,272 bp
  • A to T, chromosome 2 at 158,204,711 bp
  • A to G, chromosome 2 at 163,028,093 bp
  • A to T, chromosome 2 at 169,886,406 bp
  • A to G, chromosome 3 at 30,896,295 bp
  • T to A, chromosome 3 at 63,697,977 bp
  • G to T, chromosome 3 at 82,541,354 bp
  • T to C, chromosome 3 at 87,754,286 bp
  • A to G, chromosome 3 at 87,800,452 bp
  • T to C, chromosome 3 at 144,846,381 bp
  • A to G, chromosome 3 at 159,615,571 bp
  • A to T, chromosome 4 at 43,182,780 bp
  • A to G, chromosome 4 at 43,570,107 bp
  • C to T, chromosome 5 at 122,882,416 bp
  • T to C, chromosome 5 at 127,504,924 bp
  • T to G, chromosome 5 at 129,112,311 bp
  • C to A, chromosome 5 at 134,729,654 bp
  • C to T, chromosome 5 at 135,337,614 bp
  • C to A, chromosome 5 at 137,520,332 bp
  • G to A, chromosome 6 at 29,438,666 bp
  • A to G, chromosome 6 at 42,591,430 bp
  • A to G, chromosome 6 at 48,596,530 bp
  • C to A, chromosome 6 at 83,197,586 bp
  • T to C, chromosome 7 at 4,128,184 bp
  • T to A, chromosome 7 at 4,519,406 bp
  • C to T, chromosome 7 at 4,943,916 bp
  • A to T, chromosome 7 at 6,570,023 bp
  • C to T, chromosome 7 at 26,309,035 bp
  • C to A, chromosome 7 at 29,019,741 bp
  • G to A, chromosome 7 at 31,053,878 bp
  • T to C, chromosome 7 at 44,471,411 bp
  • T to C, chromosome 7 at 44,541,484 bp
  • C to T, chromosome 7 at 79,711,589 bp
  • T to A, chromosome 7 at 84,940,911 bp
  • T to A, chromosome 7 at 86,585,884 bp
  • T to G, chromosome 7 at 98,069,499 bp
  • A to T, chromosome 7 at 101,484,567 bp
  • T to A, chromosome 7 at 104,411,504 bp
  • T to C, chromosome 7 at 127,273,477 bp
  • T to A, chromosome 7 at 134,917,667 bp
  • A to G, chromosome 7 at 141,791,008 bp
  • A to G, chromosome 8 at 46,837,833 bp
  • A to T, chromosome 8 at 120,634,260 bp
  • A to G, chromosome 9 at 27,056,072 bp
  • T to C, chromosome 9 at 38,976,000 bp
  • C to A, chromosome 9 at 44,405,238 bp
  • G to T, chromosome 9 at 44,881,142 bp
  • A to G, chromosome 9 at 67,953,860 bp
  • C to T, chromosome 9 at 79,774,164 bp
  • C to T, chromosome 9 at 114,443,032 bp
  • A to G, chromosome 10 at 27,031,127 bp
  • T to G, chromosome 10 at 110,746,343 bp
  • A to G, chromosome 11 at 43,172,745 bp
  • G to A, chromosome 11 at 43,189,613 bp
  • G to A, chromosome 11 at 66,108,301 bp
  • T to C, chromosome 11 at 70,031,370 bp
  • T to A, chromosome 11 at 72,457,268 bp
  • C to T, chromosome 11 at 72,900,633 bp
  • T to G, chromosome 11 at 77,476,342 bp
  • T to A, chromosome 11 at 82,917,799 bp
  • T to C, chromosome 11 at 97,664,976 bp
  • T to A, chromosome 11 at 98,690,964 bp
  • T to G, chromosome 11 at 99,915,018 bp
  • A to G, chromosome 11 at 102,885,298 bp
  • T to A, chromosome 11 at 114,751,928 bp
  • T to C, chromosome 11 at 116,306,411 bp
  • T to C, chromosome 11 at 116,841,314 bp
  • T to G, chromosome 11 at 119,543,316 bp
  • A to C, chromosome 12 at 4,315,819 bp
  • T to C, chromosome 13 at 98,260,791 bp
  • A to T, chromosome 13 at 100,535,029 bp
  • A to G, chromosome 13 at 100,612,470 bp
  • C to T, chromosome 14 at 66,309,262 bp
  • G to C, chromosome 15 at 58,314,978 bp
  • T to C, chromosome 15 at 66,683,898 bp
  • A to T, chromosome 15 at 100,313,168 bp
  • C to T, chromosome 16 at 5,245,308 bp
  • A to T, chromosome 16 at 17,844,977 bp
  • T to C, chromosome 16 at 37,062,097 bp
  • T to C, chromosome 16 at 90,224,342 bp
  • G to T, chromosome 17 at 5,433,470 bp
  • A to G, chromosome 17 at 34,039,677 bp
  • T to C, chromosome 17 at 34,600,703 bp
  • C to T, chromosome 17 at 46,240,896 bp
  • T to C, chromosome 17 at 47,687,294 bp
  • A to C, chromosome 17 at 56,125,600 bp
  • G to C, chromosome 17 at 57,255,135 bp
  • C to A, chromosome 17 at 73,494,266 bp
  • T to C, chromosome 18 at 36,287,750 bp
  • G to T, chromosome 18 at 84,209,793 bp
  • T to C, chromosome 19 at 10,571,603 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2259 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040259-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.