Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR2873Btlr/Mmmh
Stock Number:
040461-MU
Citation ID:
RRID:MMRRC_040461-MU
Other Names:
R2873 (G1), C57BL/6J-MtgxR2873Btlr
Major Collection:

Gene Information

Matr3
Name: matrin 3
Synonyms: 2810017I02Rik, 1110061A14Rik, D030046F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17184
HGNC: HGNC:6912
Homologene: 7830
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 11287
HGNC: null
Homologene: 104112
Plin2
Name: perilipin 2
Synonyms: Adfp, adipophilin, ADPH, Adrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11520
HGNC: HGNC:248
Homologene: 872
Slc27a4
Name: solute carrier family 27 (fatty acid transporter), member 4
Synonyms: fatty acid transport protein 4, FATP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 26569
Homologene: 68437
Slit3
Name: slit guidance ligand 3
Synonyms: Slit1, b2b2362.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20564
Homologene: 2303
St5
Name: suppression of tumorigenicity 5
Synonyms: 2010004M01Rik, 2610305K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76954
Homologene: 3951
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: 2610315D21Rik, FKBP-rapamycin-associated protein FRAP, Frap1, RAPT1, RAFT1, mechanistic target of rapamycin (serine/threonine kinase), flat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Ybx3
Name: Y box protein 3
Synonyms: Dpba, Csda, oxyR, dbpA, MSY4, MSY3, Yb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56449
HGNC: HGNC:2428
Homologene: 2708
Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: Adprt1, 5830444G22Rik, parp-1, Adprp, sPARP-1, PARP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11545
HGNC: HGNC:270
Homologene: 1222
Nomo1
Name: nodal modulator 1
Synonyms: D7Ertd156e, Nomo, PM5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 211548
Homologene: 13810
Eif4enif1
Name: eukaryotic translation initiation factor 4E nuclear import factor 1
Synonyms: A930019J01Rik, D11Ertd166e, Clast4, 2610509L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74203
Homologene: 10522
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214133
Homologene: 49498
Tbc1d8
Name: TBC1 domain family, member 8
Synonyms: AD3, GRAM domain, BUB2-like protein 1, HBLP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54610
Homologene: 31421
Myo9b
Name: myosin IXb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Als2cr6, Alsin, 3222402C23Rik, 9430073A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Chek2
Name: checkpoint kinase 2
Synonyms: Rad53, CHK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50883
Homologene: 38289
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269608
Homologene: 10768
St7
Name: suppression of tumorigenicity 7
Synonyms: Fam4a2, TSG7, SEN4, HELG, 9430001H04Rik, RAY1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 64213
Homologene: 10185
Ostc
Name: oligosaccharyltransferase complex subunit (non-catalytic)
Synonyms: 5730557H03Rik, 2310008M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66357
Homologene: 10933
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 170935
Homologene: 15781
Ppp1r7
Name: protein phosphatase 1, regulatory subunit 7
Synonyms: SDS22, 2310014J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 66385
HGNC: HGNC:9295
Homologene: 2032
Gucy2c
Name: guanylate cyclase 2c
Synonyms: GC-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14917
HGNC: HGNC:4688
Homologene: 3641
Pms2
Name: PMS1 homolog2, mismatch repair system component
Synonyms: mismatch repair, DNA mismatch repair
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18861
HGNC: HGNC:9122
Homologene: 133560
Slc39a8
Name: solute carrier family 39 (metal ion transporter), member 8
Synonyms: BIGM103, ZIP8, 4933419D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67547
Homologene: 11155
Fan1
Name: FANCD2/FANCI-associated nuclease 1
Synonyms: 6030441H18Rik, Mtmr15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330554
Homologene: 45598
Acvr1
Name: activin A receptor, type 1
Synonyms: Alk-2, Acvr1a, ALK2, Acvr, Alk8, ActRIA, D330013D15Rik, Acvrlk2, ActR-I, Tsk7L, SKR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11477
HGNC: HGNC:171
Homologene: 7
Notch1
Name: notch 1
Synonyms: lin-12, Tan1, N1, Motch A, 9930111A19Rik, Mis6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18128
HGNC: HGNC:7881
Homologene: 32049
Pes1
Name: pescadillo ribosomal biogenesis factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 64934
HGNC: HGNC:8848
Homologene: 5984
Atp6v1g1
Name: ATPase, H+ transporting, lysosomal V1 subunit G1
Synonyms: ATP6J, Vma10, Atp6g1, 1810024D14Rik, VAG1, lysosomal 13kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66290
HGNC: HGNC:864
Homologene: 31272
Rnf6
Name: ring finger protein (C3H2C3 type) 6
Synonyms: 5730419H05Rik, 1200013I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74132
Homologene: 14036
Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Synonyms: 5830412M15Rik, 9930026A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227197
HGNC: HGNC:7707
Homologene: 3670
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
Homologene: 55776
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: Atp1al1, cHKA, HKalpha2, ATPase H+K+-transporting, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 192113
VEGA: 14
Homologene: 68197
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Plcz1
Name: phospholipase C, zeta 1
Synonyms: 1700041H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 114875
Homologene: 23815
Vwa7
Name: von Willebrand factor A domain containing 7
Synonyms: D17H6S56E-3, G7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27762
Homologene: 11895
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216225
VEGA: 10
Homologene: 64832
Hdhd2
Name: haloacid dehalogenase-like hydrolase domain containing 2
Synonyms: 3110052N05Rik, 0610039H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 76987
Homologene: 12667
Kpna7
Name: karyopherin alpha 7 (importin alpha 8)
Synonyms: importin alpha 2, LOC381686
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381686
Homologene: 73467
Ralgds
Name: ral guanine nucleotide dissociation stimulator
Synonyms: RalGDS, Rgds, Gnds
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19730
HGNC: HGNC:9842
Homologene: 4562
Nlrp4b
Name: NLR family, pyrin domain containing 4B
Synonyms: Nalp-gamma, Nalp4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 210045
HGNC: null
Homologene: 65242
Abca8b
Name: ATP-binding cassette, sub-family A (ABC1), member 8b
Synonyms: Abca8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Zfp53
Name: zinc finger protein 53
Synonyms: KRAZ1, Zfp-53, zfas8, Zfp118, D030067O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 24132
VEGA: 17
HGNC: null
Homologene: 135946
Plcl1
Name: phospholipase C-like 1
Synonyms: PRIP-1, PLC-L, C230017K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227120
HGNC: HGNC:9063
Homologene: 38155
Cd101
Name: CD101 antigen
Synonyms: Igsf2, LOC381460
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Shoc1
Name: shortage in chiasmata 1
Synonyms: LOC242489, Gm426, AI481877, Mzip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100155
Homologene: 79783
Mdm1
Name: transformed mouse 3T3 cell double minute 1
Synonyms: Mdm-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17245
VEGA: 10
Homologene: 9692
Sppl2c
Name: signal peptide peptidase 2C
Synonyms: 4933407P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237958
Homologene: 18491
Albfm1
Name: albumin superfamily member 1
Synonyms: ARG, Gm17754, 5830473C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 622307
HGNC: null
Homologene: 129803
Palmd
Name: palmdelphin
Synonyms: PALML, 4631423C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 114301
Homologene: 9804
Flnc
Name: filamin C, gamma
Synonyms: actin binding protein 280, Fln2, 1110055E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Olfr801
Name: olfactory receptor 801
Synonyms: GA_x6K02T2PULF-11349138-11348182, MOR110-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258282
HGNC: null
Homologene: 138306
Mlxip
Name: MLX interacting protein
Synonyms: Mir, bHLHe36, Mondoa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208104
Homologene: 22851
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 213402
Homologene: 41848
Msh5
Name: mutS homolog 5
Synonyms: Mut5, G7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Tnni3k
Name: TNNI3 interacting kinase
Synonyms: D830019J24Rik, Cark
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 435766
Homologene: 41084
Odf3l2
Name: outer dense fiber of sperm tails 3-like 2
Synonyms: LOC382384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382384
VEGA: 10
Homologene: 16801
Notum
Name: notum palmitoleoyl-protein carboxylesterase
Synonyms: 5730593N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 77583
Homologene: 45335
Vmn2r68
Name: vomeronasal 2, receptor 68
Synonyms: EG620697, Vmn2r68-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620697
HGNC: null
Homologene: 115466
Olfr1510
Name: olfactory receptor 1510
Synonyms: GA_x6K02T2RJGY-583652-584608, MOR223-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258423
HGNC: HGNC:8170
Homologene: 87788
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Fafl2, Dffry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 107868
Homologene: 68408
Sgk2
Name: serum/glucocorticoid regulated kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27219
Homologene: 8446
Ptger4
Name: prostaglandin E receptor 4 (subtype EP4)
Synonyms: Ptgerep4, EP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 19219
HGNC: HGNC:9596
Homologene: 20261
Tafa2
Name: TAFA chemokine like family member 2
Synonyms: Sam2, Tafa-2, Fam19a2, Tafa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 268354
VEGA: 10
Homologene: 18678
Gbp11
Name: guanylate binding protein 11
Synonyms: Gm7141
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 634650
Homologene: 128731
Ankrd40
Name: ankyrin repeat domain 40
Synonyms: 5530600A18Rik, Gcap15, 1110011C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71452
Homologene: 12393
Atp13a2
Name: ATPase type 13A2
Synonyms: 1110012E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74772
Homologene: 56940
Ch25h
Name: cholesterol 25-hydroxylase
Synonyms: m25OH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12642
VEGA: 19
HGNC: HGNC:1907
Homologene: 2942
Gm813
Name: predicted gene 813
Synonyms: LOC385656, LOC328695
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 328695
VEGA: 16
HGNC: null
Homologene: null
Cyp4a14
Name: cytochrome P450, family 4, subfamily a, polypeptide 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13119
HGNC: null
Homologene: 134697
Gm5519
Name: predicted pseudogene 5519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 433241
VEGA: 19
HGNC: null
Homologene: null
Olfr419
Name: olfactory receptor 419
Synonyms: GA_x6K02T2P20D-20891507-20892448, MOR267-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258710
Homologene: 72017
Psmb8
Name: proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
Synonyms: Lmp7, Lmp-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16913
HGNC: HGNC:9545
Homologene: 56499
Ccdc59
Name: coiled-coil domain containing 59
Synonyms: 2300004H16Rik, D10Ertd718e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52713
Homologene: 32208
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 14,887,620 bp
  • A to G, chromosome 1 at 39,405,317 bp
  • A to T, chromosome 1 at 55,697,150 bp
  • A to G, chromosome 1 at 59,211,137 bp
  • A to G, chromosome 1 at 63,164,723 bp
  • T to A, chromosome 1 at 93,357,863 bp
  • A to T, chromosome 1 at 150,738,716 bp
  • T to C, chromosome 1 at 174,250,526 bp
  • A to G, chromosome 1 at 180,573,665 bp
  • A to G, chromosome 2 at 26,460,235 bp
  • A to G, chromosome 2 at 28,548,769 bp
  • T to C, chromosome 2 at 29,809,652 bp
  • G to A, chromosome 2 at 58,477,796 bp
  • A to G, chromosome 2 at 162,994,529 bp
  • A to T, chromosome 3 at 101,003,848 bp
  • T to C, chromosome 3 at 116,923,751 bp
  • T to C, chromosome 3 at 130,703,508 bp
  • C to T, chromosome 3 at 133,486,954 bp
  • T to A, chromosome 3 at 135,886,793 bp
  • C to T, chromosome 3 at 154,938,750 bp
  • A to C, chromosome 4 at 59,093,850 bp
  • A to G, chromosome 4 at 63,550,021 bp
  • A to G, chromosome 4 at 86,668,678 bp
  • C to A, chromosome 4 at 115,487,301 bp
  • T to C, chromosome 4 at 141,002,983 bp
  • T to A, chromosome 4 at 148,540,030 bp
  • T to A, chromosome 4 at 152,107,503 bp
  • G to T, chromosome 5 at 89,135,764 bp
  • T to A, chromosome 5 at 90,569,595 bp
  • C to T, chromosome 5 at 105,331,000 bp
  • C to A, chromosome 5 at 110,863,336 bp
  • A to G, chromosome 5 at 123,452,667 bp
  • C to A, chromosome 5 at 143,357,929 bp
  • G to A, chromosome 5 at 143,911,914 bp
  • T to C, chromosome 5 at 144,993,935 bp
  • T to C, chromosome 5 at 146,210,405 bp
  • C to T, chromosome 6 at 17,819,277 bp
  • A to G, chromosome 6 at 29,447,543 bp
  • A to T, chromosome 6 at 128,485,556 bp
  • G to A, chromosome 6 at 131,370,413 bp
  • G to A, chromosome 6 at 136,765,593 bp
  • A to G, chromosome 6 at 140,016,074 bp
  • C to T, chromosome 7 at 10,710,243 bp
  • C to A, chromosome 7 at 46,046,937 bp
  • A to G, chromosome 7 at 64,363,190 bp
  • A to C, chromosome 7 at 85,233,626 bp
  • A to T, chromosome 7 at 109,557,430 bp
  • G to A, chromosome 8 at 71,334,337 bp
  • C to T, chromosome 10 at 41,966,700 bp
  • G to A, chromosome 10 at 79,645,653 bp
  • A to G, chromosome 10 at 88,904,963 bp
  • A to T, chromosome 10 at 105,841,527 bp
  • A to G, chromosome 10 at 118,150,942 bp
  • A to T, chromosome 10 at 123,704,365 bp
  • A to T, chromosome 10 at 129,669,759 bp
  • C to T, chromosome 11 at 3,242,586 bp
  • C to A, chromosome 11 at 3,976,834 bp
  • G to T, chromosome 11 at 35,544,793 bp
  • T to C, chromosome 11 at 94,333,945 bp
  • C to T, chromosome 11 at 104,187,315 bp
  • A to G, chromosome 11 at 109,955,176 bp
  • A to G, chromosome 11 at 120,660,196 bp
  • T to G, chromosome 14 at 52,410,861 bp
  • A to G, chromosome 14 at 56,386,950 bp
  • T to C, chromosome 15 at 5,234,805 bp
  • A to T, chromosome 16 at 58,613,979 bp
  • A to T, chromosome 17 at 21,508,078 bp
  • T to C, chromosome 17 at 34,200,170 bp
  • G to A, chromosome 17 at 35,021,242 bp
  • G to T, chromosome 17 at 35,029,181 bp
  • T to A, chromosome 18 at 35,572,296 bp
  • T to C, chromosome 18 at 76,955,006 bp
  • A to C, chromosome 19 at 33,825,010 bp
  • T to A, chromosome 19 at 34,474,810 bp
  • T to A, chromosome Y at 1,310,502 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2873 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040461-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.