Strain Name:
C57BL/6J-MtgxR2920Btlr/Mmmh
Stock Number:
040505-MU
Citation ID:
RRID:MMRRC_040505-MU
Other Names:
R2920 (G1), C57BL/6J-MtgxR2920Btlr
Major Collection:

Gene Information

Myo10
Name: myosin X
Synonyms: myosin-X, D15Ertd600e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Ep400
Name: E1A binding protein p400
Synonyms: 1700020J09Rik, mDomino, p400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75560
Homologene: 38779
Sdf2
Name: stromal cell derived factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20316
Homologene: 5045
Lrch2
Name: leucine-rich repeats and calponin homology (CH) domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 210297
Homologene: 32491
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229543
Homologene: 11309
Atrx
Name: ATRX, chromatin remodeler
Synonyms: 4833408C14Rik, Rad54, alpha thalassemia/mental retardation syndrome X-linked, DXHXS6677E, XH2, Xnp, HP1-BP38, Hp1bp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 22589
HGNC: HGNC:886
Homologene: 416
Myo9b
Name: myosin IXb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Mettl25
Name: methyltransferase like 25
Synonyms: BC067068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216292
Homologene: 32774
Adam11
Name: a disintegrin and metallopeptidase domain 11
Synonyms: Mdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11488
HGNC: HGNC:189
Homologene: 7614
Crebbp
Name: CREB binding protein
Synonyms: KAT3A, CBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Fgfr3
Name: fibroblast growth factor receptor 3
Synonyms: sam3, Fgfr-3, HBGFR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14184
HGNC: HGNC:3690
Homologene: 55437
Cops7a
Name: COP9 signalosome subunit 7A
Synonyms: D6Ertd35e, COP9 complex S7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 26894
Homologene: 22685
Edrf1
Name: erythroid differentiation regulatory factor 1
Synonyms: 2700050L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 214764
Homologene: 27985
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: MPP9, MPP-9, B930097C17Rik, 9630025B04Rik, 4930548D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Tmem107
Name: transmembrane protein 107
Synonyms: 1110004B13Rik, 2810049P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66910
Homologene: 12052
Zbtb1
Name: zinc finger and BTB domain containing 1
Synonyms: C430003J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 268564
Homologene: 8974
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Pak6
Name: p21 (RAC1) activated kinase 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214230
Homologene: 23200
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328783
VEGA: 17
HGNC: null
Homologene: 18633
Il12rb2
Name: interleukin 12 receptor, beta 2
Synonyms: IL-12RB2, Ifnm, A930027I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16162
HGNC: HGNC:5972
Homologene: 1197
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mgr1, Mass1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Slc13a5
Name: solute carrier family 13 (sodium-dependent citrate transporter), member 5
Synonyms: Nact, Indy, NaC2/NaCT, mINDY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237831
Homologene: 21941
Olfr702
Name: olfactory receptor 702
Synonyms: MOR260-4, GA_x6K02T2PBJ9-9202245-9201289
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258590
HGNC: null
Homologene: 121512
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232156
Homologene: 31125
Chl1
Name: cell adhesion molecule L1-like
Synonyms: close homolog of L1, LICAM2, A530023M13Rik, CALL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Rint1
Name: RAD50 interactor 1
Synonyms: 2810450M21Rik, 1500019C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72772
Homologene: 11070
Gm5155
Name: predicted gene 5155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381852
HGNC: null
Homologene: 115938
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71310
Homologene: 57079
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215772
Homologene: 100289
Slc38a7
Name: solute carrier family 38, member 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234595
Homologene: 41237
Pcdh8
Name: protocadherin 8
Synonyms: Papc, 1700080P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18530
HGNC: HGNC:8660
Homologene: 1943
Elmo3
Name: engulfment and cell motility 3
Synonyms: CED-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234683
Homologene: 23475
Slc14a2
Name: solute carrier family 14 (urea transporter), member 2
Synonyms: UT-A3, UT-A5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 27411
VEGA: 18
Homologene: 5183
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229927
HGNC: null
Homologene: 135610
Vmn1r19
Name: vomeronasal 1 receptor 19
Synonyms: V1rc27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171200
HGNC: null
Homologene: 134034
Flot2
Name: flotillin 2
Synonyms: reggie-2, Esa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14252
HGNC: HGNC:3758
Homologene: 3293
Olfr1353
Name: olfactory receptor 1353
Synonyms: GA_x6K02T2QGN0-2842591-2841662, MOR139-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 259044
HGNC: null
Homologene: 131345
Ecm1
Name: extracellular matrix protein 1
Synonyms: p85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13601
HGNC: HGNC:3153
Homologene: 3260
Ugt2b5
Name: UDP glucuronosyltransferase 2 family, polypeptide B5
Synonyms: Udpgt-3, m-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22238
Homologene: 137225
Tcerg1l
Name: transcription elongation regulator 1-like
Synonyms: 5730476P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 70571
Homologene: 52165
Glb1l
Name: galactosidase, beta 1-like
Synonyms: 4833408P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74577
Homologene: 75208
Olfr30
Name: olfactory receptor 30
Synonyms: MTPCR07, GA_x6K02T2NKPP-957001-957948, MOR281-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18329
HGNC: null
Homologene: 131139
Vmn2r69
Name: vomeronasal 2, receptor 69
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330581
HGNC: null
Homologene: 115466
Lin7b
Name: lin-7 homolog B (C. elegans)
Synonyms: Veli2, MALS-2, LIN-7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22342
Homologene: 22648
Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: E330010H22Rik, uPFK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 170768
HGNC: HGNC:8874
Homologene: 88708
Gm10093
Name: predicted pseudogene 10093
Synonyms: EG15181
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15181
VEGA: 17
HGNC: null
Homologene: null
Mepe
Name: matrix extracellular phosphoglycoprotein with ASARM motif (bone)
Synonyms: OF45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 94111
Homologene: 10623
Atp2b3
Name: ATPase, Ca++ transporting, plasma membrane 3
Synonyms: Pmca3, 6430519O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 320707
HGNC: HGNC:816
Homologene: 123775
Aloxe3
Name: arachidonate lipoxygenase 3
Synonyms: e-LOX-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23801
Homologene: 8013
Comtd1
Name: catechol-O-methyltransferase domain containing 1
Synonyms: MT773, 1810030M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 69156
Homologene: 41703
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 75,209,190 bp
  • C to T, chromosome 2 at 11,484,327 bp
  • A to T, chromosome 2 at 118,694,007 bp
  • T to C, chromosome 3 at 90,393,162 bp
  • A to T, chromosome 3 at 95,736,998 bp
  • T to A, chromosome 3 at 144,837,853 bp
  • C to T, chromosome 3 at 144,846,931 bp
  • A to G, chromosome 5 at 23,805,402 bp
  • A to G, chromosome 5 at 33,733,940 bp
  • A to G, chromosome 5 at 87,125,407 bp
  • C to T, chromosome 5 at 104,338,247 bp
  • C to A, chromosome 5 at 110,755,914 bp
  • G to A, chromosome 5 at 124,261,006 bp
  • A to T, chromosome 6 at 57,404,924 bp
  • C to T, chromosome 6 at 67,360,568 bp
  • T to C, chromosome 6 at 83,264,387 bp
  • C to A, chromosome 6 at 103,695,343 bp
  • A to G, chromosome 6 at 124,962,362 bp
  • T to A, chromosome 7 at 17,909,085 bp
  • A to G, chromosome 7 at 45,368,397 bp
  • T to A, chromosome 7 at 85,411,765 bp
  • C to T, chromosome 7 at 106,824,364 bp
  • T to A, chromosome 7 at 133,667,572 bp
  • T to C, chromosome 7 at 138,248,379 bp
  • A to G, chromosome 8 at 71,325,857 bp
  • T to C, chromosome 8 at 83,210,469 bp
  • A to G, chromosome 8 at 95,845,943 bp
  • A to G, chromosome 8 at 105,308,059 bp
  • A to G, chromosome 10 at 10,390,243 bp
  • A to C, chromosome 10 at 78,970,012 bp
  • A to T, chromosome 10 at 105,765,177 bp
  • T to C, chromosome 11 at 58,455,577 bp
  • T to C, chromosome 11 at 69,071,421 bp
  • C to T, chromosome 11 at 69,142,923 bp
  • T to C, chromosome 11 at 72,247,791 bp
  • C to T, chromosome 11 at 78,054,887 bp
  • G to C, chromosome 11 at 78,254,854 bp
  • T to C, chromosome 11 at 102,771,906 bp
  • T to A, chromosome 12 at 76,385,845 bp
  • C to T, chromosome 13 at 81,448,865 bp
  • A to G, chromosome 14 at 21,847,618 bp
  • C to T, chromosome 14 at 33,956,018 bp
  • G to T, chromosome 14 at 79,768,714 bp
  • G to T, chromosome 15 at 25,801,140 bp
  • A to G, chromosome 16 at 4,119,082 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • A to G, chromosome 17 at 78,492,846 bp
  • G to T, chromosome 18 at 78,158,297 bp
  • A to C, chromosome X at 73,533,920 bp
  • A to T, chromosome X at 105,830,868 bp
  • A to T, chromosome X at 147,473,030 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2920 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040505-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.