Strain Name:
C57BL/6J-MtgxR2938Btlr/Mmmh
Stock Number:
040515-MU
Citation ID:
RRID:MMRRC_040515-MU
Other Names:
R2938 (G1), C57BL/6J-MtgxR2938Btlr
Major Collection:

Gene Information

Myo10
Name: myosin X
Synonyms: D15Ertd600e, myosin-X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Gpr83
Name: G protein-coupled receptor 83
Synonyms: GIR, RP82, glucocorticoid-induced receptor, Gpr72, RP105, Gir, RP39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14608
HGNC: HGNC:4523
Homologene: 7732
Prss12
Name: protease, serine 12 neurotrypsin (motopsin)
Synonyms: motopsin, Bssp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19142
HGNC: HGNC:9477
Homologene: 7490
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Acf7, Aclp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Arfgef2
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99371
Homologene: 111880
Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: Red, 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Pdss1
Name: prenyl (solanesyl) diphosphate synthase, subunit 1
Synonyms: mSPS1, Tprt, 2610203G20Rik, 2700031G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56075
Homologene: 5353
Cdc6
Name: cell division cycle 6
Synonyms: cell division cycle 18 homolog (S.pombe)-like, CDC18L, CDC18(S.pombe)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23834
HGNC: HGNC:1744
Homologene: 68172
Mib1
Name: mindbomb E3 ubiquitin protein ligase 1
Synonyms: E430019M12Rik, Mib, mind bomb-1, skeletrophin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225164
Homologene: 10810
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 277854
Homologene: 34718
Utp4
Name: UTP4 small subunit processome component
Synonyms: TEG-292, Tex292, Cirh1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21771
HGNC: HGNC:1983
Homologene: 40775
Xpo4
Name: exportin 4
Synonyms: B430309A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57258
Homologene: 10733
Fkbp15
Name: FK506 binding protein 15
Synonyms: FKBP133, C430014M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 338355
Homologene: 28743
Xpo7
Name: exportin 7
Synonyms: 4930506C02Rik, Ranbp16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 65246
VEGA: 14
Homologene: 22857
Htr2b
Name: 5-hydroxytryptamine (serotonin) receptor 2B
Synonyms: 5-HT2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15559
HGNC: HGNC:5294
Homologene: 55492
Rbm10
Name: RNA binding motif protein 10
Synonyms: E430039K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 236732
HGNC: HGNC:9896
Homologene: 31330
Lrrtm1
Name: leucine rich repeat transmembrane neuronal 1
Synonyms: 4632401D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74342
Homologene: 41763
Tmub1
Name: transmembrane and ubiquitin-like domain containing 1
Synonyms: Hops, 2010004O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64295
Homologene: 11187
Parm1
Name: prostate androgen-regulated mucin-like protein 1
Synonyms: 2210012L08Rik, 9130213B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231440
Homologene: 41036
Zfp808
Name: zinc finger protein 808
Synonyms: Gm7036
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 630579
Homologene: 134631
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Cola2, Cola-2, Col1a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Sec31b
Name: Sec31 homolog B (S. cerevisiae)
Synonyms: LOC240667, Sec31l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240667
Homologene: 56708
Rap1gap2
Name: RAP1 GTPase activating protein 2
Synonyms: Garnl4, LOC380710
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380711
Homologene: 56695
Csn1s1
Name: casein alpha s1
Synonyms: Csna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12990
HGNC: HGNC:2445
Ccdc73
Name: coiled-coil domain containing 73
Synonyms: 2210415I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211936
Homologene: 52235
Astn2
Name: astrotactin 2
Synonyms: Astnl, 1d8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56079
Homologene: 77850
Ifna11
Name: interferon alpha 11
Synonyms: IFN-[a]11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15964
HGNC: HGNC:5425
Homologene: 68536
Pfkfb2
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Synonyms: PFK-2/FBPase-2 gene B, 4930568D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18640
HGNC: HGNC:8873
Homologene: 88554
Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: 9030624O13Rik, NHE-3, NHE3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105243
VEGA: 13
Homologene: 55804
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Wdsub1
Name: WD repeat, SAM and U-box domain containing 1
Synonyms: 2610014F08Rik, 1700048E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72137
Homologene: 17609
Postn
Name: periostin, osteoblast specific factor
Synonyms: peri, A630052E07Rik, Periostin, Osf2, OSF-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50706
Homologene: 4730
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237711
Homologene: 104282
Cstl1
Name: cystatin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228756
Homologene: 16283
Sh3rf2
Name: SH3 domain containing ring finger 2
Synonyms: 9130023G24Rik, RNF158
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269016
Homologene: 17618
Man1c1
Name: mannosidase, alpha, class 1C, member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230815
Homologene: 69303
Olfr1032
Name: olfactory receptor 1032
Synonyms: GA_x6K02T2Q125-47485813-47486745, MOR199-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258572
Homologene: 17299
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: CDA13, 1110059C24Rik, CEAP1, ASP21, ALP56, BAE2, ARP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Cdr1
Name: cerebellar degeneration related antigen 1
Synonyms: Gm7077, Gm2409, Cdr34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 631990
VEGA: X
Cdh15
Name: cadherin 15
Synonyms: M cadherin, Cdh14, Mcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Tlr1
Name: toll-like receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21897
Homologene: 20694
Vmn1r35
Name: vomeronasal 1 receptor 35
Synonyms: V1rc12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171185
Homologene: 110800
Olfr792
Name: olfactory receptor 792
Synonyms: GA_x6K02T2PULF-11219415-11220350, MOR108-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258150
Homologene: 133881
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 627569
Homologene: 129606
Sgcg
Name: sarcoglycan, gamma (dystrophin-associated glycoprotein)
Synonyms: gamma-SG, 5430420E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 24053
Homologene: 194
Man2b2
Name: mannosidase 2, alpha B2
Synonyms: 135 kDa alpha-D-mannosidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17160
Homologene: 7411
Lmod1
Name: leiomodin 1 (smooth muscle)
Synonyms: 64kD D1, 9530015K06Rik, SM-Lmod, D1, 1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 93689
HGNC: HGNC:6647
Homologene: 8118
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70719
Homologene: 69120
Glis1
Name: GLIS family zinc finger 1
Synonyms: GliH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230587
Homologene: 77390
Olfr984
Name: olfactory receptor 984
Synonyms: GA_x6K02T2PVTD-33799484-33798540, MOR239-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258601
VEGA: 9
Homologene: 17314
Cela3b
Name: chymotrypsin-like elastase family, member 3B
Synonyms: Ela3, 2310074F01Rik, 0910001F22Rik, Ela3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67868
Homologene: 128227
Vamp5
Name: vesicle-associated membrane protein 5
Synonyms: Camp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53620
Homologene: 4833
Uck1
Name: uridine-cytidine kinase 1
Synonyms: URK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22245
Homologene: 7990
Cbarp
Name: calcium channel, voltage-dependent, beta subunit associated regulatory protein
Synonyms: Dos, R29144/1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100503659
Homologene: 82309
Gimap8
Name: GTPase, IMAP family member 8
Synonyms: IAN9, LOC243374
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243374
Homologene: 69703
Nsun5
Name: NOL1/NOP2/Sun domain family, member 5
Synonyms: Wbscr20a, 9830109N13Rik, Nol1r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100609
Homologene: 6828
1700013F07Rik
Name: RIKEN cDNA 1700013F07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75504
Homologene: 18986
Saraf
Name: store-operated calcium entry-associated regulatory factor
Synonyms: 1810045K07Rik, Tmem66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67887
Homologene: 9398
Ccdc59
Name: coiled-coil domain containing 59
Synonyms: 2300004H16Rik, D10Ertd718e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52713
Homologene: 32208
A630014C17Rik
Name: RIKEN cDNA A630014C17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 63,549,733 bp
  • T to A, chromosome 1 at 86,102,455 bp
  • G to A, chromosome 1 at 130,705,410 bp
  • A to G, chromosome 1 at 135,363,916 bp
  • T to A, chromosome 2 at 22,906,787 bp
  • GCCAACACC to GCC, chromosome 2 at 32,256,076 bp
  • T to C, chromosome 2 at 59,873,286 bp
  • T to C, chromosome 2 at 86,008,013 bp
  • T to A, chromosome 2 at 104,975,635 bp
  • T to A, chromosome 2 at 148,751,057 bp
  • T to A, chromosome 2 at 166,894,733 bp
  • T to A, chromosome 3 at 54,370,310 bp
  • C to T, chromosome 3 at 108,544,173 bp
  • A to G, chromosome 3 at 123,486,976 bp
  • T to A, chromosome 4 at 62,304,663 bp
  • A to T, chromosome 4 at 65,992,313 bp
  • T to C, chromosome 4 at 88,820,293 bp
  • A to G, chromosome 4 at 107,632,291 bp
  • T to C, chromosome 4 at 123,432,902 bp
  • A to G, chromosome 4 at 134,702,952 bp
  • A to G, chromosome 4 at 137,423,263 bp
  • A to G, chromosome 5 at 24,445,924 bp
  • G to A, chromosome 5 at 32,901,621 bp
  • A to G, chromosome 5 at 36,820,986 bp
  • A to G, chromosome 5 at 62,842,957 bp
  • A to G, chromosome 5 at 64,925,908 bp
  • A to T, chromosome 5 at 87,677,136 bp
  • T to C, chromosome 5 at 91,594,469 bp
  • C to T, chromosome 5 at 109,091,531 bp
  • C to T, chromosome 5 at 135,375,463 bp
  • A to T, chromosome 6 at 4,520,788 bp
  • A to T, chromosome 6 at 48,658,796 bp
  • A to T, chromosome 6 at 66,678,966 bp
  • A to G, chromosome 6 at 72,369,340 bp
  • A to T, chromosome 6 at 77,243,652 bp
  • A to G, chromosome 8 at 34,168,581 bp
  • A to G, chromosome 8 at 106,922,929 bp
  • G to A, chromosome 8 at 122,862,024 bp
  • A to G, chromosome 9 at 14,864,871 bp
  • A to T, chromosome 9 at 40,100,743 bp
  • T to A, chromosome 10 at 80,029,002 bp
  • T to C, chromosome 10 at 80,131,769 bp
  • A to T, chromosome 10 at 105,841,527 bp
  • T to A, chromosome 10 at 129,540,615 bp
  • G to A, chromosome 11 at 29,833,049 bp
  • A to T, chromosome 11 at 52,282,783 bp
  • C to A, chromosome 11 at 74,407,322 bp
  • A to G, chromosome 11 at 98,910,760 bp
  • G to A, chromosome 13 at 62,171,218 bp
  • T to C, chromosome 13 at 74,121,669 bp
  • G to A, chromosome 13 at 96,663,068 bp
  • G to T, chromosome 14 at 57,604,440 bp
  • A to T, chromosome 14 at 61,229,625 bp
  • A to G, chromosome 14 at 70,671,690 bp
  • T to A, chromosome 15 at 25,795,717 bp
  • T to C, chromosome 16 at 97,412,188 bp
  • T to A, chromosome 18 at 10,752,033 bp
  • A to G, chromosome 18 at 42,149,724 bp
  • T to C, chromosome 19 at 44,536,179 bp
  • T to C, chromosome X at 20,647,695 bp
  • T to G, chromosome X at 61,185,362 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2938 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040515-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.