Strain Name:
C57BL/6J-MtgxR3037Btlr/Mmmh
Stock Number:
040553-MU
Citation ID:
RRID:MMRRC_040553-MU
Other Names:
R3037 (G1), C57BL/6J-MtgxR3037Btlr
Major Collection:

Gene Information

Cntnap2
Name: contactin associated protein-like 2
Synonyms: 5430425M22Rik, Caspr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66797
Homologene: 69159
Ptprk
Name: protein tyrosine phosphatase, receptor type, K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Lrig3
Name: leucine-rich repeats and immunoglobulin-like domains 3
Synonyms: 9030421L11Rik, 9430095K15Rik, 9130004I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320398
VEGA: 10
Homologene: 62452
Topors
Name: topoisomerase I binding, arginine/serine-rich
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 106021
Homologene: 4237
Zc3h4
Name: zinc finger CCCH-type containing 4
Synonyms: Bwq1, Kiaa1064-hp, LOC330474
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330474
Homologene: 87150
Ythdf3
Name: YTH N6-methyladenosine RNA binding protein 3
Synonyms: 9130022A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229096
Homologene: 34991
Usp15
Name: ubiquitin specific peptidase 15
Synonyms: Gcap18, 4921514G19Rik, E430033I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14479
VEGA: 10
Homologene: 101542
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: Hps2, beta3A, rim2, recombination induced mutation 2, AP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Nup214
Name: nucleoporin 214
Synonyms: CAN, D2H9S46E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Ets2
Name: E26 avian leukemia oncogene 2, 3' domain
Synonyms: Ets-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 23872
HGNC: HGNC:3489
Homologene: 3838
Tspan5
Name: tetraspanin 5
Synonyms: 4930505M03Rik, Tm4sf9, NET-4, 2810455A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56224
Homologene: 4182
Cit
Name: citron
Synonyms: CRIK-SK, Cit-k, C030025P15Rik, citron-N, citron kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665775
Homologene: 45109
Cdh19
Name: cadherin 19, type 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227485
HGNC: HGNC:1758
Homologene: 23286
Kctd10
Name: potassium channel tetramerisation domain containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330171
Homologene: 32652
Cat
Name: catalase
Synonyms: Cas-1, Cs-1, Cas1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12359
HGNC: HGNC:1516
Homologene: 55514
Pced1a
Name: PC-esterase domain containing 1A
Synonyms: A930025D01Rik, Fam113a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319513
Homologene: 11241
Scaf1
Name: SR-related CTD-associated factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233208
Fcsk
Name: fucose kinase
Synonyms: Fuk, L-fucose kinase, 1110046B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234730
Homologene: 15452
Pdlim4
Name: PDZ and LIM domain 4
Synonyms: Ril
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 30794
Homologene: 2735
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Naip-rs6, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Il11ra1
Name: interleukin 11 receptor, alpha chain 1
Synonyms: Il11ra, Il-11ra, NR1, Il-11ra-alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16157
HGNC: HGNC:5967
Homologene: 88705
Dll3
Name: delta like canonical Notch ligand 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13389
HGNC: HGNC:2909
Homologene: 7291
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Ltrpc5, 9430099A16Rik, Mtr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56843
Homologene: 22818
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546983
Homologene: 115466
Gsdmc2
Name: gasdermin C2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 331063
HGNC: HGNC:7151
Homologene: 69487
Plce1
Name: phospholipase C, epsilon 1
Synonyms: 4933403A21Rik, PLCepsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74055
Homologene: 9478
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: CLR16.2, D230007K08Rik, Caterpiller 16.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268857
Homologene: 18720
Pth1r
Name: parathyroid hormone 1 receptor
Synonyms: PPR, PTH/PTHrP receptor, PTH-related peptide receptor, PTH1R, Pthr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19228
HGNC: HGNC:9608
Homologene: 267
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: 1700030F18Rik, LOC380973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72277
Rad21l
Name: RAD21-like (S. pombe)
Synonyms: Gm14160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668929
Homologene: 82650
Olfr228
Name: olfactory receptor 228
Synonyms: MOR189-3, GA_x6K02T0101M-139-669
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258400
Homologene: 17233
Pcdhb1
Name: protocadherin beta 1
Synonyms: PcdhbA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93872
HGNC: HGNC:8680
Homologene: 8348
Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
Synonyms: Aarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224805
VEGA: 17
Homologene: 56897
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 215384
Homologene: 68369
Nanog
Name: Nanog homeobox
Synonyms: ENK, ecat4, 2410002E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71950
Homologene: 78027
Kcnab2
Name: potassium voltage-gated channel, shaker-related subfamily, beta member 2
Synonyms: I2rf5, F5, Kcnb3, I2rf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16498
HGNC: HGNC:6229
Homologene: 56492
Bco1
Name: beta-carotene oxygenase 1
Synonyms: Bcdo, Bcmo1, Cmoi, beta-CD, Bcdo1, betaCMOOX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 63857
Homologene: 41172
4932415M13Rik
Name: RIKEN cDNA 4932415M13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 211496
Ttyh3
Name: tweety family member 3
Synonyms: 2900029G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78339
Homologene: 18431
Gng11
Name: guanine nucleotide binding protein (G protein), gamma 11
Synonyms: 0610037B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66066
HGNC: HGNC:4403
Homologene: 3045
Pdia6
Name: protein disulfide isomerase associated 6
Synonyms: CaBP5, Txndc7, P5, 1700015E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71853
Homologene: 4198
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 110,954,607 bp
  • A to T, chromosome 2 at 31,976,620 bp
  • A to T, chromosome 2 at 86,483,643 bp
  • A to G, chromosome 2 at 103,467,777 bp
  • A to C, chromosome 2 at 130,419,859 bp
  • A to T, chromosome 2 at 151,660,780 bp
  • T to C, chromosome 3 at 16,205,191 bp
  • G to A, chromosome 3 at 138,898,355 bp
  • C to T, chromosome 4 at 40,269,673 bp
  • T to A, chromosome 4 at 41,765,074 bp
  • T to A, chromosome 4 at 152,393,756 bp
  • A to T, chromosome 5 at 41,822,037 bp
  • A to G, chromosome 5 at 114,375,000 bp
  • G to T, chromosome 5 at 115,971,389 bp
  • C to A, chromosome 5 at 140,648,842 bp
  • A to G, chromosome 6 at 4,008,051 bp
  • G to A, chromosome 6 at 46,015,266 bp
  • C to A, chromosome 6 at 122,713,268 bp
  • A to G, chromosome 7 at 16,421,485 bp
  • A to G, chromosome 7 at 28,102,702 bp
  • A to G, chromosome 7 at 28,299,117 bp
  • T to C, chromosome 7 at 45,007,347 bp
  • A to T, chromosome 7 at 86,800,983 bp
  • G to A, chromosome 7 at 143,085,463 bp
  • A to T, chromosome 8 at 110,894,718 bp
  • A to G, chromosome 8 at 117,127,539 bp
  • G to A, chromosome 9 at 110,724,504 bp
  • T to C, chromosome 10 at 28,580,478 bp
  • C to A, chromosome 10 at 123,163,617 bp
  • A to G, chromosome 10 at 126,010,032 bp
  • C to A, chromosome 11 at 54,056,257 bp
  • C to T, chromosome 12 at 17,279,645 bp
  • T to C, chromosome 13 at 94,445,978 bp
  • A to C, chromosome 13 at 100,154,949 bp
  • A to T, chromosome 15 at 63,833,331 bp
  • G to T, chromosome 15 at 99,943,794 bp
  • T to C, chromosome 16 at 3,952,408 bp
  • C to A, chromosome 16 at 95,716,065 bp
  • G to A, chromosome 17 at 45,519,823 bp
  • T to A, chromosome 17 at 53,724,361 bp
  • T to G, chromosome 18 at 37,265,113 bp
  • G to A, chromosome 19 at 38,777,884 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3037 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040553-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.