Strain Name:
C57BL/6J-MtgxR3150Btlr/Mmmh
Stock Number:
040602-MU
Citation ID:
RRID:MMRRC_040602-MU
Other Names:
R3150 (G1), C57BL/6J-MtgxR3150Btlr
Major Collection:

Gene Information

Pkd1
Name: polycystin 1, transient receptor poteintial channel interacting
Synonyms: PC1, PC-1, polycystin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: D230017O13Rik, 2610103K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 268281
Homologene: 6489
Ppp2r2a
Name: protein phosphatase 2, regulatory subunit B, alpha
Synonyms: 2410004D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71978
VEGA: 14
HGNC: HGNC:9304
Homologene: 2035
Nmral1
Name: NmrA-like family domain containing 1
Synonyms: 1110025F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67824
Homologene: 41388
Spats1
Name: spermatogenesis associated, serine-rich 1
Synonyms: 4933400B06Rik, 1700011H05Rik, Srsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71020
VEGA: 17
Homologene: 12376
Srgap2
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: Fnbp2, FBP2, 9930124L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14270
Homologene: 52683
Rtn4
Name: reticulon 4
Synonyms: Nogo-B, Nogo-A, C130026I10Rik, NOGO, 1110020G17Rik, NgA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68585
Homologene: 10743
Cabin1
Name: calcineurin binding protein 1
Synonyms: Cain, Ppp3in, A330070M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 104248
VEGA: 10
Homologene: 49307
Gpatch2l
Name: G patch domain containing 2 like
Synonyms: 1700020O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 70373
VEGA: 12
Homologene: 9942
Usp22
Name: ubiquitin specific peptidase 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216825
Homologene: 52664
Ddb1
Name: damage specific DNA binding protein 1
Synonyms: p127-Ddb1, DNA repair protein, damage-specific DNA-binding protein, DNA repair
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13194
VEGA: 19
HGNC: HGNC:2717
Homologene: 1448
Git2
Name: GIT ArfGAP 2
Synonyms: Cat-2, 5830420E16Rik, 9630056M03Rik, B230104M05Rik, Cool associated tyrosine phosphorylated-2, ARF GTPase activating protein 2, 1500036H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26431
HGNC: HGNC:4273
Homologene: 41336
Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: MLTKbeta, MLTKalpha, Zak, B230120H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65964
Homologene: 32331
Wdr62
Name: WD repeat domain 62
Synonyms: b2b1508Clo, 2310038K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233064
Homologene: 15927
Zswim7
Name: zinc finger SWIM-type containing 7
Synonyms: SWS1, 2410012H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69747
Homologene: 15565
Xpo5
Name: exportin 5
Synonyms: 2410004H11Rik, Exp5, 2700038C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72322
VEGA: 17
Homologene: 69316
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19876
Homologene: 2206
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Hnrnph1
Name: heterogeneous nuclear ribonucleoprotein H1
Synonyms: E430005G16Rik, Hnrph1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 59013
HGNC: HGNC:5041
Homologene: 31318
Cyp4f18
Name: cytochrome P450, family 4, subfamily f, polypeptide 18
Synonyms: 1810054N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72054
HGNC: HGNC:2645
Homologene: 128623
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: alpha3(IV), tumstatin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Mapk11
Name: mitogen-activated protein kinase 11
Synonyms: Sapk2, p38beta, Prkm11, P38b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 19094
VEGA: 15
HGNC: HGNC:6873
Homologene: 55684
BC067074
Name: cDNA sequence BC067074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 408066
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: PRDI-BF1, b2b1765Clo, Blimp1, Blimp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319482
Homologene: 130055
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20957
Homologene: 2389
Akna
Name: AT-hook transcription factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100182
Homologene: 49947
Olfr860
Name: olfactory receptor 860
Synonyms: MOR146-2, GA_x6K02T2PVTD-13586614-13585661
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258521
Homologene: 134093
Csf2ra
Name: colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Synonyms: Csfgmra, GM-CSF-Ra, GM-CSFRalpha, CD116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12982
VEGA: 19
HGNC: HGNC:2435
Homologene: 48406
Itgad
Name: integrin, alpha D
Synonyms: Cd11d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381924
HGNC: HGNC:6146
Homologene: 56919
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: TIE, tie-1, D430008P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21846
Homologene: 3957
Padi6
Name: peptidyl arginine deiminase, type VI
Synonyms: Padi5, ePAD, Pad6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242726
Homologene: 17695
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70950
VEGA: 18
Homologene: 12373
Mrc2
Name: mannose receptor, C type 2
Synonyms: Endo180, novel lectin, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17534
Homologene: 4408
Sry
Name: sex determining region of Chr Y
Synonyms: Tdf, Tdy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 21674
Ces1g
Name: carboxylesterase 1G
Synonyms: Ces-1, Ses-1, Ces1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12623
HGNC: HGNC:1863
Homologene: 137354
Olfr1475
Name: olfactory receptor 1475
Synonyms: MOR202-36, GA_x6K02T2RE5P-3812807-3811863
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258298
Homologene: 77370
Gm2128
Name: predicted gene 2128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100039269
Homologene: 45597
Zswim9
Name: zinc finger SWIM-type containing 9
Synonyms: 6330408A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 321008
Homologene: 52386
Hao2
Name: hydroxyacid oxidase 2
Synonyms: Hao3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 56185
HGNC: HGNC:4810
Homologene: 97412
Gm5592
Name: predicted gene 5592
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434172
Homologene: 45597
Adprh
Name: ADP-ribosylarginine hydrolase
Synonyms: Arh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 11544
VEGA: 16
HGNC: HGNC:269
Homologene: 874
Olfr1231
Name: olfactory receptor 1231
Synonyms: MOR235-2, GA_x6K02T2Q125-50748233-50747292
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258446
Homologene: 27168
Vmn2r32
Name: vomeronasal 2, receptor 32
Synonyms: V2r5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22311
Homologene: 113703
Gzmk
Name: granzyme K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14945
HGNC: HGNC:4711
Homologene: 20485
Gfod2
Name: glucose-fructose oxidoreductase domain containing 2
Synonyms: 5730466C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70575
Homologene: 10361
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 82,657,137 bp
  • T to C, chromosome 1 at 131,292,589 bp
  • C to T, chromosome 2 at 72,371,992 bp
  • C to T, chromosome 2 at 89,303,218 bp
  • T to C, chromosome 3 at 98,880,328 bp
  • G to A, chromosome 3 at 102,898,841 bp
  • A to T, chromosome 4 at 63,395,353 bp
  • G to A, chromosome 4 at 118,475,825 bp
  • A to G, chromosome 4 at 140,735,389 bp
  • A to C, chromosome 4 at 145,086,790 bp
  • A to G, chromosome 5 at 114,730,349 bp
  • T to C, chromosome 7 at 7,472,555 bp
  • T to C, chromosome 7 at 13,277,270 bp
  • C to A, chromosome 7 at 28,154,195 bp
  • A to T, chromosome 7 at 30,271,670 bp
  • A to G, chromosome 7 at 41,158,148 bp
  • A to G, chromosome 7 at 41,288,380 bp
  • C to A, chromosome 7 at 128,190,981 bp
  • T to C, chromosome 8 at 71,993,200 bp
  • C to T, chromosome 8 at 93,325,816 bp
  • C to T, chromosome 8 at 105,717,221 bp
  • A to G, chromosome 9 at 19,846,214 bp
  • A to G, chromosome 10 at 11,170,030 bp
  • A to T, chromosome 10 at 44,458,492 bp
  • A to G, chromosome 10 at 75,656,911 bp
  • CGAGGAGGAGGAGGAGGA to CGAGGAGGAGGAGGA, chromosome 11 at 29,693,308 bp
  • T to A, chromosome 11 at 50,385,792 bp
  • T to C, chromosome 11 at 61,160,581 bp
  • A to T, chromosome 11 at 62,273,785 bp
  • G to A, chromosome 11 at 105,348,431 bp
  • A to G, chromosome 12 at 86,244,315 bp
  • T to A, chromosome 13 at 113,173,920 bp
  • A to T, chromosome 13 at 113,351,760 bp
  • G to A, chromosome 14 at 67,023,765 bp
  • T to C, chromosome 15 at 89,145,450 bp
  • G to A, chromosome 16 at 4,716,469 bp
  • G to T, chromosome 16 at 38,446,107 bp
  • C to T, chromosome 16 at 72,970,269 bp
  • G to T, chromosome 17 at 24,579,791 bp
  • A to T, chromosome 17 at 45,464,554 bp
  • A to G, chromosome 17 at 46,242,247 bp
  • G to T, chromosome 18 at 22,067,652 bp
  • T to A, chromosome 19 at 10,612,982 bp
  • A to G, chromosome 19 at 13,479,460 bp
  • C to A, chromosome 19 at 61,227,320 bp
  • ACTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTG to ACTGCTGCTGCTGCTGCTGCTGCTGCTGCTG, chromosome Y at 2,662,944 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3150 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040602-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.