Strain Name:
C57BL/6J-MtgxR3419Btlr/Mmmh
Stock Number:
040637-MU
Citation ID:
RRID:MMRRC_040637-MU
Other Names:
R3419 (G1), C57BL/6J-MtgxR3419Btlr
Major Collection:

Gene Information

Armc9
Name: armadillo repeat containing 9
Synonyms: 5730415N24Rik, 4831423D23Rik, 3830422A13Rik, 4930438O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78795
Homologene: 11847
Exoc5
Name: exocyst complex component 5
Synonyms: SEC10, Sec10l1, PRO1912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105504
Homologene: 38195
Sel1l
Name: sel-1 suppressor of lin-12-like (C. elegans)
Synonyms: Sel1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20338
Homologene: 31286
Bend3
Name: BEN domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 331623
VEGA: 10
Homologene: 19511
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: RPC155, RPC1, 9330175N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218832
VEGA: 14
Homologene: 5124
Serpini1
Name: serine (or cysteine) peptidase inhibitor, clade I, member 1
Synonyms: Spi17, PI12, Ns, Neuroserpin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20713
HGNC: HGNC:8943
Homologene: 21045
Dmbx1
Name: diencephalon/mesencephalon homeobox 1
Synonyms: Otx3, Dmbx1, Mbx, Atx, Cdmx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 140477
Homologene: 15639
Fntb
Name: farnesyltransferase, CAAX box, beta
Synonyms: 2010013E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110606
HGNC: HGNC:3785
Homologene: 1535
Ptcd3
Name: pentatricopeptide repeat domain 3
Synonyms: 2810422B04Rik, 2610034F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69956
Homologene: 41211
Gucy1a1
Name: guanylate cyclase 1, soluble, alpha 1
Synonyms: alpha 1 sGC, Gucy1a3, sGC-alpha1, 1200016O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 60596
HGNC: HGNC:4685
Homologene: 37360
Unc5b
Name: unc-5 netrin receptor B
Synonyms: D10Bwg0792e, 6330415E02Rik, Unc5h2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 107449
VEGA: 10
Homologene: 32538
Lyn
Name: LYN proto-oncogene, Src family tyrosine kinase
Synonyms: Yamaguchi sarcoma viral (v-yes-1) oncogene homolog, Hck-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17096
HGNC: HGNC:6735
Homologene: 55649
Hoxd10
Name: homeobox D10
Synonyms: Hox-5.3, Hox-4.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15430
HGNC: HGNC:5133
Homologene: 1619
Dpy19l2
Name: dpy-19-like 2 (C. elegans)
Synonyms: 4932443J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320752
VEGA: 9
Homologene: 77569
Flrt2
Name: fibronectin leucine rich transmembrane protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 399558
HGNC: HGNC:3761
Homologene: 8291
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Acf1, Gtl5, Wcrf180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Mapk6
Name: mitogen-activated protein kinase 6
Synonyms: Prkm4, Erk3, Prkm6, Mapk63, D130053K17Rik, Mapk4, ERK3, 2610021I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 50772
HGNC: HGNC:6879
Homologene: 55683
Poc5
Name: POC5 centriolar protein
Synonyms: 1200014M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67463
VEGA: 13
Homologene: 12141
Snrnp48
Name: small nuclear ribonucleoprotein 48 (U11/U12)
Synonyms: 6530403A03Rik, 1110050F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67797
VEGA: 13
Homologene: 12191
Ankrd26
Name: ankyrin repeat domain 26
Synonyms: 5730521P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232339
Homologene: 45968
Gga2
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 2
Synonyms: 1200007E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74105
Homologene: 22860
Dync2i1
Name: dynein 2 intermediate chain 1
Synonyms: D430033N04Rik, Dync2l1, Wdr60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217935
VEGA: 12
Homologene: 23067
Fchsd2
Name: FCH and double SH3 domains 2
Synonyms: Sh3md3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207278
Homologene: 8887
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Clec9a
Name: C-type lectin domain family 9, member a
Synonyms: DNGR-1, 9830005G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232414
Homologene: 52106
St6galnac4
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Synonyms: ST6GalNAc IV, Siat7d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20448
Homologene: 7939
Rnf168
Name: ring finger protein 168
Synonyms: 3110001H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70238
Homologene: 87044
Ppp1r3a
Name: protein phosphatase 1, regulatory subunit 3A
Synonyms: RGL, GM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 140491
HGNC: HGNC:9291
Homologene: 48124
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: NaG, 1110034K09Rik, Nav2.3, Nav2, Scn6a, Nax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20272
Homologene: 55706
Cdh5
Name: cadherin 5
Synonyms: VEcad, VE-cadherin, CD144, VECD, 7B4/cadherin-5, VEC, VE-Cad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Vmn2r2
Name: vomeronasal 2, receptor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100125586
Homologene: 129753
Mbd6
Name: methyl-CpG binding domain protein 6
Synonyms: D10Wsu93e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110962
Homologene: 14171
Tulp2
Name: tubby-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56734
Homologene: 2492
5530400C23Rik
Name: RIKEN cDNA 5530400C23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232426
Homologene: 79760
Tdrd1
Name: tudor domain containing 1
Synonyms: MTR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83561
Homologene: 12850
Gm4736
Name: predicted gene 4736
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100502592
Vmn2r9
Name: vomeronasal 2, receptor 9
Synonyms: EG435864
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 435864
Homologene: 129606
Lacc1
Name: laccase domain containing 1
Synonyms: 9030625A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 210808
Homologene: 17712
Slco6b1
Name: solute carrier organic anion transporter family, member 6b1
Synonyms: 1700022M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67854
Homologene: 12199
Fam20c
Name: FAM20C, golgi associated secretory pathway kinase
Synonyms: DMP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 80752
Homologene: 56879
P2ry1
Name: purinergic receptor P2Y, G-protein coupled 1
Synonyms: P2Y1, P2Y1 receptor, P2y1r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18441
HGNC: HGNC:8539
Homologene: 1926
Gsto1
Name: glutathione S-transferase omega 1
Synonyms: GSTX, p28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14873
Homologene: 37971
Klk14
Name: kallikrein related-peptidase 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 317653
HGNC: HGNC:6362
Homologene: 69348
Olfr672
Name: olfactory receptor 672
Synonyms: MOR32-4, GA_x6K02T2PBJ9-7625746-7624808
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258755
Homologene: 138317
Olfr93
Name: olfactory receptor 93
Synonyms: MOR256-39P, GA_x6K02T2PSCP-1592036-1591098
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258051
HGNC: HGNC:8252
Homologene: 79436
Eef2k
Name: eukaryotic elongation factor-2 kinase
Synonyms: eEF-2K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13631
Homologene: 7299
Kcnj13
Name: potassium inwardly-rectifying channel, subfamily J, member 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040591
HGNC: HGNC:6259
Homologene: 55638
Olfr146
Name: olfactory receptor 146
Synonyms: MOR171-10, M15, GA_x6K02T2PVTD-32715386-32714466
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258742
VEGA: 9
Serpinb13
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
Synonyms: HUR7, headpin, PI13, HURPIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241196
HGNC: HGNC:8944
Homologene: 22718
Tmem30c
Name: transmembrane protein 30C
Synonyms: 4933409A18Rik, 4933401B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71027
Homologene: 78138
AI987944
Name: expressed sequence AI987944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233168
Ids
Name: iduronate 2-sulfatase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 15931
HGNC: HGNC:5389
Homologene: 169
Vmn1r175
Name: vomeronasal 1 receptor 175
Synonyms: Gm6299
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 622222
Homologene: 128341
Paqr3
Name: progestin and adipoQ receptor family member III
Synonyms: 6330415A20Rik, RKTG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231474
Homologene: 71077
Ndufa13
Name: NADH:ubiquinone oxidoreductase subunit A13
Synonyms: GRIM-19, 2700054G14Rik, CGI-39, CDA016, Grim19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67184
Homologene: 41083
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 14,874,381 bp
  • T to C, chromosome 1 at 86,194,338 bp
  • T to C, chromosome 1 at 87,386,919 bp
  • T to C, chromosome 1 at 90,804,091 bp
  • T to C, chromosome 1 at 96,942,033 bp
  • T to C, chromosome 1 at 106,998,927 bp
  • A to G, chromosome 2 at 32,595,731 bp
  • AT to ATT, chromosome 2 at 66,700,895 bp
  • A to G, chromosome 2 at 74,692,577 bp
  • T to C, chromosome 3 at 61,003,712 bp
  • A to T, chromosome 3 at 64,116,899 bp
  • A to G, chromosome 3 at 75,640,282 bp
  • A to G, chromosome 3 at 82,106,133 bp
  • A to T, chromosome 4 at 3,746,833 bp
  • G to C, chromosome 4 at 115,920,676 bp
  • A to G, chromosome 5 at 97,099,700 bp
  • A to C, chromosome 5 at 108,846,433 bp
  • A to T, chromosome 5 at 138,757,868 bp
  • A to T, chromosome 6 at 14,719,414 bp
  • A to T, chromosome 6 at 71,883,486 bp
  • A to G, chromosome 6 at 118,535,107 bp
  • A to G, chromosome 6 at 129,421,038 bp
  • A to T, chromosome 6 at 132,115,677 bp
  • A to G, chromosome 6 at 133,294,119 bp
  • A to T, chromosome 7 at 23,808,650 bp
  • C to G, chromosome 7 at 41,376,737 bp
  • G to A, chromosome 7 at 43,692,077 bp
  • T to A, chromosome 7 at 45,518,752 bp
  • T to A, chromosome 7 at 101,278,660 bp
  • A to G, chromosome 7 at 104,996,520 bp
  • T to A, chromosome 7 at 120,885,870 bp
  • C to T, chromosome 7 at 122,003,998 bp
  • A to G, chromosome 8 at 69,894,492 bp
  • C to T, chromosome 8 at 104,129,370 bp
  • T to C, chromosome 9 at 24,581,205 bp
  • C to T, chromosome 9 at 39,019,076 bp
  • T to C, chromosome 9 at 75,397,757 bp
  • T to C, chromosome 10 at 43,509,982 bp
  • G to A, chromosome 10 at 60,778,814 bp
  • C to A, chromosome 10 at 74,584,222 bp
  • C to G, chromosome 10 at 127,286,503 bp
  • T to C, chromosome 12 at 54,946,899 bp
  • C to A, chromosome 12 at 76,887,888 bp
  • A to G, chromosome 12 at 91,810,002 bp
  • A to G, chromosome 12 at 95,780,604 bp
  • C to T, chromosome 12 at 116,224,977 bp
  • G to A, chromosome 13 at 38,221,359 bp
  • A to T, chromosome 13 at 96,404,417 bp
  • A to G, chromosome 14 at 24,467,035 bp
  • A to T, chromosome 14 at 49,023,278 bp
  • T to G, chromosome 14 at 77,034,881 bp
  • A to G, chromosome 16 at 32,299,192 bp
  • A to G, chromosome 16 at 57,277,668 bp
  • A to T, chromosome 17 at 37,151,351 bp
  • T to C, chromosome 19 at 47,857,905 bp
  • T to A, chromosome 19 at 56,831,231 bp
  • A to G, chromosome X at 70,353,284 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3419 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040637-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.