Strain Name:
C57BL/6J-MtgxR3841Btlr/Mmmh
Stock Number:
040781-MU
Citation ID:
RRID:MMRRC_040781-MU
Other Names:
R3841 (G1), C57BL/6J-MtgxR3841Btlr
Major Collection:

Gene Information

Rcan2
Name: regulator of calcineurin 2
Synonyms: ZAKI-4, Csp2, MCIP2, Dscr1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 53901
VEGA: 17
HGNC: HGNC:3041
Homologene: 130985
Utp20
Name: UTP20 small subunit processome component
Synonyms: 3830408P06Rik, mDRIM, DRIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70683
VEGA: 10
Homologene: 38373
Osbpl1a
Name: oxysterol binding protein-like 1A
Synonyms: LOC328902, G430090F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 64291
Homologene: 84746
Eef1e1
Name: eukaryotic translation elongation factor 1 epsilon 1
Synonyms: 1110003A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66143
VEGA: 13
HGNC: HGNC:3212
Homologene: 3161
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, Cxxc7, Mll, ALL-1, Mll1, All1, HTRX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Epc2
Name: enhancer of polycomb homolog 2
Synonyms: D2Ertd694e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227867
Homologene: 32274
Nr2c2
Name: nuclear receptor subfamily 2, group C, member 2
Synonyms: TAK1, Tr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22026
HGNC: HGNC:7972
Homologene: 2475
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: C030027K23Rik, E230037B21Rik, PH5P, Adprtl1, p193, VAULT3, VPARP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Zfp617
Name: zinc finger protein 617
Synonyms: Zfps11-6, Zinc finger protein s11-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170938
Homologene: 135689
Hsph1
Name: heat shock 105kDa/110kDa protein 1
Synonyms: HSP110, hsp110/105, Hsp105, hsp-E7I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15505
Homologene: 21322
Hipk2
Name: homeodomain interacting protein kinase 2
Synonyms: Stank, B230339E18Rik, 1110014O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15258
Homologene: 68766
Dsp
Name: desmoplakin
Synonyms: DP, 5730453H04Rik, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Adcy1
Name: adenylate cyclase 1
Synonyms: D11Bwg1392e, I-AC, AC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Susd1
Name: sushi domain containing 1
Synonyms: Gm12528
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 634731
Homologene: 11204
F11r
Name: F11 receptor
Synonyms: Jcam1, JAM-A, BV11 antigen, Ly106, ESTM33, JAM-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16456
Homologene: 14255
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: 6430556C10Rik, netrin g1 ligand
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241568
Homologene: 18696
Selenok
Name: selenoprotein K
Synonyms: HSPC030, 30kDa, Selk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 80795
Homologene: 56870
Bmper
Name: BMP-binding endothelial regulator
Synonyms: Cv2, CV-2, Crim3, crossveinless-2, 3110056H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73230
VEGA: 9
Homologene: 12494
C8b
Name: complement component 8, beta polypeptide
Synonyms: 4930439B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110382
HGNC: HGNC:1353
Homologene: 48
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68591
VEGA: 18
Homologene: 9931
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E16Rik, 2310076E21Rik, Myospryn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Rdh19
Name: retinol dehydrogenase 19
Synonyms: Rdhs, RDH-S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216453
Homologene: 129514
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Me3
Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Synonyms: 1700020C08Rik, B230207H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 109264
HGNC: HGNC:6985
Homologene: 100773
Map3k10
Name: mitogen-activated protein kinase kinase kinase 10
Synonyms: mixed lineage kinase 2, MKN28 kinase, serine/threonine kinase, MKN28 derived nonreceptor_type, Mlk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269881
HGNC: HGNC:6849
Homologene: 1834
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Impdh1
Name: inosine monophosphate dehydrogenase 1
Synonyms: B930086D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 23917
HGNC: HGNC:6052
Homologene: 68096
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: LOC268884, 4632417D23Rik, 5530401I02Rik, 9530025L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 77446
Homologene: 35276
Rap1gap
Name: Rap1 GTPase-activating protein
Synonyms: Rap1ga1, 2310004O14Rik, 1300019I11Rik, Gap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110351
HGNC: HGNC:9858
Homologene: 2163
Ldlrap1
Name: low density lipoprotein receptor adaptor protein 1
Synonyms: Arh, Arh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100017
Homologene: 9219
Olfr593
Name: olfactory receptor 593
Synonyms: MOR24-2, GA_x6K02T2PBJ9-5927412-5928362
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258378
Homologene: 27147
CT025661.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Tbpl1
Name: TATA box binding protein-like 1
Synonyms: TLF, TRP, Tlp, TRF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237336
Homologene: 3577
Fam83c
Name: family with sequence similarity 83, member C
Synonyms: 5530400B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71405
Homologene: 18669
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: SAPLT, 1700056N23Rik, 1700042F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Ptprb
Name: protein tyrosine phosphatase, receptor type, B
Synonyms: 3230402H02Rik, VE-PTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Ggt1
Name: gamma-glutamyltransferase 1
Synonyms: dwg, CD224, Ggtp, GGT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14598
HGNC: HGNC:4250
Homologene: 68450
Zfp773
Name: zinc finger protein 773
Synonyms: 2810409K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76373
Homologene: 137393
4921524L21Rik
Name: RIKEN cDNA 4921524L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70901
VEGA: 18
Homologene: 78009
Btnl7-ps
Name: butyrophilin-like 7, pseudogene
Synonyms: Btnl7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 195349
Cabp5
Name: calcium binding protein 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 29865
Homologene: 8486
Cracd
Name: capping protein inhibiting regulator of actin
Synonyms: C530008M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320827
Homologene: 136278
Jhy
Name: junctional cadherin complex regulator
Synonyms: 4931429I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70989
Homologene: 11726
Tulp1
Name: tubby like protein 1
Synonyms: Tulp1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22157
Homologene: 2491
Medag
Name: mesenteric estrogen dependent adipogenesis
Synonyms: 6330406I15Rik, MEDA-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70717
Homologene: 12364
BC035947
Name: cDNA sequence BC035947
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Olfr781
Name: olfactory receptor 781
Synonyms: GA_x6K02T2PULF-11013616-11014551, MOR114-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258723
Homologene: 37000
Otud1
Name: OTU domain containing 1
Synonyms: 4933428L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71198
Homologene: 45953
Dgcr6
Name: DiGeorge syndrome critical region gene 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13353
HGNC: HGNC:2846
Homologene: 4152
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 78,497,845 bp
  • G to T, chromosome 1 at 171,460,889 bp
  • G to T, chromosome 2 at 19,658,743 bp
  • A to G, chromosome 2 at 49,488,738 bp
  • C to A, chromosome 2 at 52,207,660 bp
  • A to G, chromosome 2 at 97,630,192 bp
  • C to T, chromosome 2 at 155,834,748 bp
  • A to G, chromosome 4 at 59,412,164 bp
  • A to G, chromosome 4 at 104,784,387 bp
  • T to C, chromosome 4 at 134,750,436 bp
  • T to C, chromosome 4 at 137,717,447 bp
  • A to T, chromosome 5 at 76,859,011 bp
  • T to A, chromosome 5 at 149,427,423 bp
  • T to A, chromosome 5 at 149,620,715 bp
  • A to G, chromosome 6 at 29,202,769 bp
  • T to C, chromosome 6 at 38,818,926 bp
  • C to T, chromosome 6 at 92,163,138 bp
  • A to G, chromosome 7 at 7,132,391 bp
  • T to A, chromosome 7 at 13,403,293 bp
  • C to A, chromosome 7 at 27,658,364 bp
  • A to T, chromosome 7 at 89,786,493 bp
  • G to A, chromosome 7 at 103,212,693 bp
  • G to A, chromosome 8 at 71,932,117 bp
  • T to A, chromosome 9 at 23,473,431 bp
  • T to A, chromosome 9 at 40,944,846 bp
  • T to C, chromosome 9 at 44,831,291 bp
  • A to T, chromosome 9 at 109,662,134 bp
  • A to G, chromosome 10 at 22,711,908 bp
  • T to A, chromosome 10 at 75,581,385 bp
  • A to G, chromosome 10 at 80,529,706 bp
  • A to T, chromosome 10 at 88,775,203 bp
  • T to C, chromosome 10 at 116,346,982 bp
  • A to T, chromosome 10 at 127,856,886 bp
  • A to G, chromosome 10 at 129,333,333 bp
  • T to C, chromosome 11 at 7,161,960 bp
  • A to C, chromosome 13 at 38,197,705 bp
  • G to A, chromosome 13 at 38,656,191 bp
  • A to G, chromosome 13 at 93,094,632 bp
  • C to T, chromosome 14 at 29,973,380 bp
  • A to T, chromosome 14 at 56,587,778 bp
  • C to A, chromosome 16 at 18,070,213 bp
  • T to A, chromosome 16 at 33,719,856 bp
  • A to G, chromosome 17 at 28,353,715 bp
  • A to G, chromosome 17 at 34,542,576 bp
  • A to G, chromosome 17 at 34,698,923 bp
  • A to G, chromosome 17 at 44,036,979 bp
  • A to T, chromosome 18 at 6,620,104 bp
  • A to G, chromosome 18 at 12,756,319 bp
  • C to T, chromosome 18 at 24,676,624 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3841 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040781-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.