Strain Name:
C57BL/6J-MtgxR3891Btlr/Mmmh
Stock Number:
040803-MU
Citation ID:
RRID:MMRRC_040803-MU
Other Names:
R3891 (G1), C57BL/6J-MtgxR3891Btlr
Major Collection:

Gene Information

Pum1
Name: pumilio RNA-binding family member 1
Synonyms: Pumm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 80912
Homologene: 22830
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4921507G06Rik, 4930435C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Zmym4
Name: zinc finger, MYM-type 4
Synonyms: Zfp262, 6330503C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67785
Homologene: 35470
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: B630009I04Rik, Helic1, ASC1p200
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, D18Wsu154e, Drf1, Dia1, Diap1, mDia1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Slc30a6
Name: solute carrier family 30 (zinc transporter), member 6
Synonyms: ZnT-6, ZnT6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210148
VEGA: 17
Homologene: 32380
Fam120c
Name: family with sequence similarity 120, member C
Synonyms: orf34, D930001I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 207375
Homologene: 9876
Polr2e
Name: polymerase (RNA) II (DNA directed) polypeptide E
Synonyms: 25kDa, RPB5, XAP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66420
HGNC: HGNC:9192
Homologene: 2018
Mob1b
Name: MOB kinase activator 1B
Synonyms: Mobkl1a, 1110003E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68473
Homologene: 61676
Def8
Name: differentially expressed in FDCP 8
Synonyms: D8Ertd713e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23854
Homologene: 14279
Pcdhb16
Name: protocadherin beta 16
Synonyms: Pcdhb8, PcdhbP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93887
HGNC: HGNC:8693
Homologene: 99843
Slc29a3
Name: solute carrier family 29 (nucleoside transporters), member 3
Synonyms: Ent3, 4933435C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71279
Homologene: 56805
Skor2
Name: SKI family transcriptional corepressor 2
Synonyms: Gm7348, Corl2, Fussel18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 664805
VEGA: 18
Homologene: 64797
Pex2
Name: peroxisomal biogenesis factor 2
Synonyms: Zellweger syndrome homolog, Pxmp3, PMP35, D3Ertd138e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19302
HGNC: HGNC:9717
Homologene: 269
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Zc3h12a
Name: zinc finger CCCH type containing 12A
Synonyms: Mcpip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230738
Homologene: 11824
Rasef
Name: RAS and EF hand domain containing
Synonyms: RAB45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242505
Homologene: 28424
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Naip-rs6, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Olfr170
Name: olfactory receptor 170
Synonyms: MOR273-2, GA_x54KRFPKG5P-16052703-16051765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258959
Homologene: 128058
Slx4
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Synonyms: Btbd12, D16Bwg1016e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 52864
Homologene: 23770
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: 2810012G08Rik, Cytsb, B230396K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432572
Homologene: 45157
Skint2
Name: selection and upkeep of intraepithelial T cells 2
Synonyms: B7S3, OTTMUSG00000008540
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329919
Homologene: 136741
Col9a1
Name: collagen, type IX, alpha 1
Synonyms: Col9a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12839
HGNC: HGNC:2217
Homologene: 1393
Nos1ap
Name: nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms: 6330408P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70729
Homologene: 135990
Dmrta1
Name: doublesex and mab-3 related transcription factor like family A1
Synonyms: Dmrt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242523
Homologene: 18477
H2-T24
Name: histocompatibility 2, T region locus 24
Synonyms: H-2T24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15042
Homologene: 69019
Vstm2a
Name: V-set and transmembrane domain containing 2A
Synonyms: 9330184N17Rik, Vstm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 211739
Homologene: 17123
Nfe2l1
Name: nuclear factor, erythroid derived 2,-like 1
Synonyms: TCF11, Lcrf1, TCF-11, NRF1, LCR-F1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18023
HGNC: HGNC:7781
Homologene: 20685
A3galt2
Name: alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
Synonyms: LOC215493, iGb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 215493
Homologene: 16326
Tmem67
Name: transmembrane protein 67
Synonyms: b2b1163.1Clo, b2b1291.1Clo, 5330408M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329795
Homologene: 71886
Il1rap
Name: interleukin 1 receptor accessory protein
Synonyms: 6430709H04Rik, IL-1R AcP, IL-1RAcP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16180
HGNC: HGNC:5995
Homologene: 1643
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 114601
VEGA: 19
Homologene: 136059
Olfr718-ps1
Name: olfactory receptor 718, pseudogene 1
Synonyms: GA_x6K02T2PH54-2346206-2347174, MOR0-10P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 258006
Olfr31
Name: olfactory receptor 31
Synonyms: MTPCR53, MOR274-1, GA_x6K02T2PLTE-6714644-6715597
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18330
HGNC: HGNC:8277
Homologene: 74028
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: Cyln2, WSCR4, CLIP-115
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212974
Homologene: 16023
Slc19a3
Name: solute carrier family 19, member 3
Synonyms: A230084E24Rik, ThTr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 80721
Homologene: 23530
Krt1
Name: keratin 1
Synonyms: Krt-2.1, Krt2-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16678
VEGA: 15
HGNC: HGNC:6412
Homologene: 38146
Slc9a7
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 7
Synonyms: NHE7, A530087D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 236727
Homologene: 32785
Nuak2
Name: NUAK family, SNF1-like kinase, 2
Synonyms: Snark, 1200013B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74137
Homologene: 12539
Clrn3
Name: clarin 3
Synonyms: Tmem12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212070
Homologene: 17544
Gm4907
Name: predicted gene 4907
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 236749
Syce1
Name: synaptonemal complex central element protein 1
Synonyms: 4933406J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74075
Homologene: 77044
Rpl13
Name: ribosomal protein L13
Synonyms: L13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270106
Homologene: 5568
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: 4932416A11Rik, WARP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 246228
Homologene: 11270
Gabrr2
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14409
HGNC: HGNC:4091
Homologene: 20471
Stard10
Name: START domain containing 10
Synonyms: CGI-52, NY-C0-28, Pctpl, PC-TP2, Sdccag28, TISP-81, PCTP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56018
Homologene: 4841
Gm10088
Name: predicted gene 10088
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 100504250
Gm5616
Name: predicted gene 5616
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 434401
VEGA: 9
C1qb
Name: complement component 1, q subcomponent, beta polypeptide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12260
HGNC: HGNC:1242
Homologene: 418
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 24,185,436 bp
  • A to T, chromosome 1 at 83,022,957 bp
  • G to T, chromosome 1 at 132,331,485 bp
  • A to T, chromosome 1 at 150,635,195 bp
  • T to C, chromosome 1 at 170,349,456 bp
  • C to T, chromosome 3 at 5,560,948 bp
  • A to G, chromosome 4 at 12,054,844 bp
  • A to G, chromosome 4 at 33,081,348 bp
  • A to G, chromosome 4 at 73,780,397 bp
  • A to T, chromosome 4 at 89,691,594 bp
  • A to G, chromosome 4 at 112,624,186 bp
  • A to G, chromosome 4 at 125,126,885 bp
  • A to G, chromosome 4 at 126,904,476 bp
  • A to G, chromosome 4 at 128,762,054 bp
  • T to C, chromosome 4 at 130,764,082 bp
  • A to T, chromosome 4 at 136,880,416 bp
  • T to C, chromosome 4 at 155,773,194 bp
  • T to A, chromosome 5 at 88,753,202 bp
  • T to C, chromosome 5 at 134,522,993 bp
  • G to T, chromosome 5 at 143,137,397 bp
  • G to A, chromosome 7 at 101,343,930 bp
  • T to C, chromosome 7 at 135,518,465 bp
  • C to A, chromosome 7 at 140,779,896 bp
  • T to C, chromosome 7 at 140,945,703 bp
  • A to G, chromosome 8 at 123,105,168 bp
  • T to C, chromosome 8 at 123,458,344 bp
  • A to T, chromosome 9 at 45,717,484 bp
  • A to G, chromosome 9 at 48,450,509 bp
  • T to A, chromosome 10 at 50,842,193 bp
  • T to A, chromosome 10 at 60,716,261 bp
  • G to T, chromosome 10 at 80,037,379 bp
  • T to A, chromosome 10 at 93,038,846 bp
  • T to C, chromosome 11 at 16,258,096 bp
  • C to T, chromosome 11 at 62,151,913 bp
  • A to G, chromosome 11 at 96,819,997 bp
  • T to A, chromosome 13 at 100,161,098 bp
  • T to A, chromosome 14 at 14,328,114 bp
  • T to A, chromosome 15 at 101,850,412 bp
  • A to T, chromosome 16 at 3,979,909 bp
  • T to C, chromosome 16 at 19,028,251 bp
  • A to G, chromosome 16 at 19,606,455 bp
  • A to G, chromosome 16 at 26,676,856 bp
  • T to A, chromosome 17 at 36,015,438 bp
  • T to A, chromosome 17 at 74,419,546 bp
  • A to T, chromosome 18 at 37,479,369 bp
  • C to A, chromosome 18 at 37,900,638 bp
  • A to G, chromosome 18 at 76,858,655 bp
  • A to G, chromosome 19 at 5,718,312 bp
  • A to G, chromosome X at 20,186,113 bp
  • A to G, chromosome X at 23,906,941 bp
  • A to G, chromosome X at 151,382,006 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3891 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040803-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.