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Strain Name:
C57BL/6J-MtgxR3892Btlr/Mmmh
Stock Number:
040804-MU
Citation ID:
RRID:MMRRC_040804-MU
Other Names:
R3892 (G1), C57BL/6J-MtgxR3892Btlr
Major Collection:

Strain Information

Cnnm2
Name: cyclin M2
Synonyms: Acdp2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94219
VEGA: 19
HGNC: HGNC:103
Homologene: 9761
Myd88
Name: myeloid differentiation primary response gene 88
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17874
HGNC: HGNC:7562
Homologene: 1849
Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: PTPk, RPTPkappa
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Zmym4
Name: zinc finger, MYM-type 4
Synonyms: 6330503C17Rik, Zfp262
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67785
Homologene: 35470
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: ASC1p200, B630009I04Rik, Helic1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, Drf1, Dia1, D18Wsu154e, mDia1, Diap1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Rcbtb1
Name: regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
Synonyms: 5430409I18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71330
Homologene: 10061
Ints9
Name: integrator complex subunit 9
Synonyms: D14Ertd231e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 210925
VEGA: 14
Homologene: 10096
Zfp407
Name: zinc finger protein 407
Synonyms: LOC240469, LOC381139, 6430585N13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240476
Homologene: 86402
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20624
Homologene: 3133
Map3k11
Name: mitogen-activated protein kinase kinase kinase 11
Synonyms: Mlk3, 2610017K16Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 26403
VEGA: 19
HGNC: HGNC:6850
Homologene: 37618
Mccc2
Name: methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
Synonyms: 4930552N12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 78038
VEGA: 13
HGNC: HGNC:6937
Homologene: 11145
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Uvssa
Name: UV stimulated scaffold protein A
Synonyms: D330017J19Rik, 4933407H18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71101
Homologene: 13807
Card6
Name: caspase recruitment domain family, member 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239319
Homologene: 13067
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Lamp5
Name: lysosomal-associated membrane protein family, member 5
Synonyms: 3110035N03Rik, BAD-LAMP, 6330527O06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76161
Homologene: 8173
Mob1b
Name: MOB kinase activator 1B
Synonyms: 1110003E08Rik, Mobkl1a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68473
Homologene: 61676
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Sp3
Name: trans-acting transcription factor 3
Synonyms: D130027J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20687
Homologene: 7952
Cckbr
Name: cholecystokinin B receptor
Synonyms: CCK-B/gastrin receptor, CCK2/gastrin, CCK2R, CCKR-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12426
HGNC: HGNC:1571
Homologene: 7258
Strip2
Name: striatin interacting protein 2
Synonyms: Myoscape, D330017J20Rik, Fam40b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320609
Homologene: 66198
Klf5
Name: Kruppel-like transcription factor 5
Synonyms: Bteb2, 4930520J07Rik, IKLF, CKLF
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12224
VEGA: 14
HGNC: HGNC:6349
Homologene: 37520
Def8
Name: differentially expressed in FDCP 8
Synonyms: D8Ertd713e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23854
Homologene: 14279
Snrnp27
Name: small nuclear ribonucleoprotein 27 (U4/U6.U5)
Synonyms: 2610209M04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66618
Homologene: 135794
Snrnp48
Name: small nuclear ribonucleoprotein 48 (U11/U12)
Synonyms: 1110050F08Rik, 6530403A03Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67797
VEGA: 13
Homologene: 12191
Rabgef1
Name: RAB guanine nucleotide exchange factor (GEF) 1
Synonyms: Ras negative regulator Rabex-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56715
Homologene: 8720
Pcdhb16
Name: protocadherin beta 16
Synonyms: PcdhbP, Pcdhb8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93887
Homologene: 99843
Robo4
Name: roundabout guidance receptor 4
Synonyms: 1200012D01Rik, Magic roundabout
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74144
Homologene: 10397
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Rasef
Name: RAS and EF hand domain containing
Synonyms: RAB45
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242505
Homologene: 28424
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, D430038H04Rik, 9430076A06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545030
Homologene: 83473
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin, B230334C09Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242274
Homologene: 10817
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Gm10801
Name: predicted gene 10801
Type: Gene
Species: Mouse
Chromosome: 2
Deup1
Name: deuterosome assembly protein 1
Synonyms: 4933401K09Rik, Ccdc67
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234964
Homologene: 18760
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, LOC235639, C030048J01Rik, Lba1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320429
Homologene: 45845
Flg
Name: filaggrin
Synonyms: profilaggrin, fillagrin, ft
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14246
VEGA: 3
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546981
Homologene: 115466
Grhpr
Name: glyoxylate reductase/hydroxypyruvate reductase
Synonyms: 6430629L09Rik, 1110059D05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76238
HGNC: HGNC:4570
Homologene: 49088
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: D030049F17Rik, Nedl2, A730039N16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329152
Homologene: 66192
Ctnnb1
Name: catenin beta 1
Synonyms: beta-catenin, Catnb, beta catenin, catenin (cadherin associated protein), beta 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12387
HGNC: HGNC:2514
Homologene: 1434
Nos1ap
Name: nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms: 6330408P19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70729
Homologene: 135990
Dmrta1
Name: doublesex and mab-3 related transcription factor like family A1
Synonyms: Dmrt4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242523
Homologene: 18477
Psg23
Name: pregnancy-specific beta-1-glycoprotein 23
Synonyms: 1620401C02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56868
HGNC: HGNC:1819
Homologene: 110989
Cd248
Name: CD248 antigen, endosialin
Synonyms: 2610111G01Rik, Tem1, Cd164l1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 70445
VEGA: 19
Homologene: 10699
Fam209
Name: family with sequence similarity 209
Synonyms: 1700029J11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76426
Homologene: 19218
Or4f15
Name: olfactory receptor family 4 subfamily F member 15
Synonyms: GA_x6K02T2Q125-73031456-73030518, MOR245-5, Olfr1309
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258439
Homologene: 74054
Tmem67
Name: transmembrane protein 67
Synonyms: 5330408M12Rik, b2b1291.1Clo, b2b1163.1Clo
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329795
Homologene: 71886
Or10ah1-ps1
Name: olfactory receptor family 10 subfamily AH member 1, pseudogene 1
Synonyms: GA_x6K02T2PH54-2346206-2347174, MOR0-10P, Olfr718-ps1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 258006
Cbs
Name: cystathionine beta-synthase
Synonyms: HIP4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12411
HGNC: HGNC:1550
Homologene: 37258
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: CLIP-115, WSCR4, Cyln2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
St8sia6
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
Synonyms: ST8Sia VI, 1700007J08Rik, Siat8f
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241230
Homologene: 17112
Slc19a3
Name: solute carrier family 19, member 3
Synonyms: ThTr2, A230084E24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 80721
Homologene: 23530
Krt1
Name: keratin 1
Synonyms: Krt2-1, Krt-2.1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16678
VEGA: 15
HGNC: HGNC:6412
Homologene: 38146
Lrrc14b
Name: leucine rich repeat containing 14B
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 432779
Homologene: 47758
Ggcx
Name: gamma-glutamyl carboxylase
Synonyms: vitamin K-dependent carboxylase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56316
HGNC: HGNC:4247
Homologene: 639
Nuak2
Name: NUAK family, SNF1-like kinase, 2
Synonyms: 1200013B22Rik, Snark
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74137
Homologene: 12539
Or7e165
Name: olfactory receptor family 7 subfamily E member 165
Synonyms: IG6, MOR146-7P, GA_x6K02T2PVTD-13523015-13523944, MOR146-3, Olfr58
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18358
Homologene: 134093
Bckdhb
Name: branched chain ketoacid dehydrogenase E1, beta polypeptide
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12040
HGNC: HGNC:987
Homologene: 39
Mipep
Name: mitochondrial intermediate peptidase
Synonyms: 5730405E07Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70478
VEGA: 14
HGNC: HGNC:7104
Homologene: 4337
Gabrr2
Name: gamma-aminobutyric acid type A receptor subunit rho 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14409
HGNC: HGNC:4091
Homologene: 20471
BC061237
Name: cDNA sequence BC061237
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 385138
Homologene: 128452
H2-M10.1
Name: histocompatibility 2, M region locus 10.1
Synonyms: 9.5H
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14985
Homologene: 117973
AC121271.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 45,406,300 bp
  • A to T, chromosome 1 at 53,926,121 bp
  • A to T, chromosome 1 at 83,022,957 bp
  • G to T, chromosome 1 at 132,331,485 bp
  • A to T, chromosome 1 at 150,635,195 bp
  • T to C, chromosome 1 at 170,349,456 bp
  • G to A, chromosome 2 at 13,672,524 bp
  • A to G, chromosome 2 at 72,979,032 bp
  • T to G, chromosome 2 at 98,663,901 bp
  • A to C, chromosome 2 at 111,983,141 bp
  • G to A, chromosome 2 at 136,059,481 bp
  • A to G, chromosome 2 at 172,472,698 bp
  • A to T, chromosome 3 at 93,279,526 bp
  • A to G, chromosome 3 at 158,160,696 bp
  • A to G, chromosome 4 at 12,054,844 bp
  • A to G, chromosome 4 at 33,081,348 bp
  • T to C, chromosome 4 at 44,990,368 bp
  • A to G, chromosome 4 at 73,780,397 bp
  • A to T, chromosome 4 at 89,691,594 bp
  • A to G, chromosome 4 at 126,904,476 bp
  • T to C, chromosome 4 at 130,764,082 bp
  • T to A, chromosome 5 at 33,389,752 bp
  • T to A, chromosome 5 at 88,753,202 bp
  • T to G, chromosome 5 at 110,336,439 bp
  • A to G, chromosome 5 at 130,208,679 bp
  • T to C, chromosome 5 at 134,522,993 bp
  • G to T, chromosome 5 at 143,137,397 bp
  • A to T, chromosome 6 at 29,917,075 bp
  • C to A, chromosome 6 at 32,215,654 bp
  • G to A, chromosome 6 at 72,418,372 bp
  • A to T, chromosome 6 at 86,681,580 bp
  • G to T, chromosome 7 at 18,612,041 bp
  • A to G, chromosome 7 at 24,064,118 bp
  • A to T, chromosome 7 at 86,164,286 bp
  • A to C, chromosome 7 at 105,426,169 bp
  • T to C, chromosome 8 at 104,616,327 bp
  • T to C, chromosome 8 at 123,458,344 bp
  • A to G, chromosome 9 at 15,599,713 bp
  • G to A, chromosome 9 at 15,998,271 bp
  • T to G, chromosome 9 at 19,783,715 bp
  • CGG to CG, chromosome 9 at 37,411,490 bp
  • A to C, chromosome 9 at 83,988,810 bp
  • T to C, chromosome 9 at 111,364,759 bp
  • T to C, chromosome 9 at 119,337,816 bp
  • T to G, chromosome 9 at 120,950,514 bp
  • A to T, chromosome 10 at 28,263,621 bp
  • T to A, chromosome 10 at 50,842,193 bp
  • A to C, chromosome 11 at 102,846,187 bp
  • G to A, chromosome 13 at 38,217,389 bp
  • T to C, chromosome 13 at 74,363,668 bp
  • T to C, chromosome 13 at 99,967,733 bp
  • T to C, chromosome 14 at 33,047,280 bp
  • A to G, chromosome 14 at 44,501,273 bp
  • T to A, chromosome 14 at 59,228,355 bp
  • T to C, chromosome 14 at 60,808,995 bp
  • T to G, chromosome 14 at 61,204,387 bp
  • A to G, chromosome 14 at 65,020,507 bp
  • T to A, chromosome 14 at 99,299,073 bp
  • T to C, chromosome 15 at 5,099,296 bp
  • T to C, chromosome 15 at 81,619,997 bp
  • T to A, chromosome 15 at 101,850,412 bp
  • C to A, chromosome 17 at 31,616,074 bp
  • T to A, chromosome 17 at 36,324,389 bp
  • A to T, chromosome 18 at 37,479,369 bp
  • C to A, chromosome 18 at 37,900,638 bp
  • C to T, chromosome 18 at 84,560,352 bp
  • C to T, chromosome 19 at 5,069,506 bp
  • G to T, chromosome 19 at 5,702,283 bp
  • T to A, chromosome 19 at 46,761,793 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3892 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040804-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.