Strain Name:
C57BL/6J-MtgxR3832Btlr/Mmmh
Stock Number:
040887-MU
Citation ID:
RRID:MMRRC_040887-MU
Other Names:
R3832 (G1), C57BL/6J-MtgxR3832Btlr
Major Collection:

Strain Information

Adamts20
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Synonyms: ADAMTS-20, bt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223838
Homologene: 11808
Gdf6
Name: growth differentiation factor 6
Synonyms: BMP13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242316
HGNC: HGNC:4221
Homologene: 40883
Slit3
Name: slit guidance ligand 3
Synonyms: Slit1, b2b2362.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20564
Homologene: 2303
Bcar3
Name: breast cancer anti-estrogen resistance 3
Synonyms: AND-34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 29815
HGNC: HGNC:973
Homologene: 31181
Phf14
Name: PHD finger protein 14
Synonyms: 1110001C23Rik, 4932409F11Rik, 5730446A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 75725
Homologene: 8775
Col6a1
Name: collagen, type VI, alpha 1
Synonyms: Col6a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12833
HGNC: HGNC:2211
Homologene: 1391
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: 6230420N16Rik, C030045D06Rik, Depdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109294
Homologene: 23523
Snd1
Name: staphylococcal nuclease and tudor domain containing 1
Synonyms: p100 co-activator, Tudor-SN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56463
Homologene: 8665
Plcg1
Name: phospholipase C, gamma 1
Synonyms: Plc-1, Plcg-1, Plc-gamma1, Cded
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18803
HGNC: HGNC:9065
Homologene: 1997
Afdn
Name: afadin, adherens junction formation factor
Synonyms: AF6, Afadin, S-afadin, I-afadin, 5033403D15Rik, Mllt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: Pir121, 6430511D02Rik, 1500004I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76884
Homologene: 7936
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67534
Homologene: 8764
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: 5230400C17Rik, Pip5k3, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18711
Homologene: 32115
Ccdc3
Name: coiled-coil domain containing 3
Synonyms: 2310045O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74186
Homologene: 12870
Klhl28
Name: kelch-like 28
Synonyms: 2810440N09Rik, 4931401E10Rik, 4122402F11Rik, Btbd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66689
VEGA: 12
Homologene: 23036
Slc39a8
Name: solute carrier family 39 (metal ion transporter), member 8
Synonyms: BIGM103, 4933419D20Rik, ZIP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67547
Homologene: 11155
Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Synonyms: Plekhe1, Phlpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98432
Homologene: 11015
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, NKF3 kinase family member, C230081A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244895
Homologene: 18259
Pdgfd
Name: platelet-derived growth factor, D polypeptide
Synonyms: 1110003I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71785
VEGA: 9
Homologene: 11875
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213945
Homologene: 66345
Tecta
Name: tectorin alpha
Synonyms: [a]-tectorin, Tctna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21683
Homologene: 3955
Hephl1
Name: hephaestin-like 1
Synonyms: LOC244698, Zp, zyklopen, thd, cw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244698
Homologene: 9112
Pus3
Name: pseudouridine synthase 3
Synonyms: 2610020J05Rik, 5730412F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67049
Homologene: 11339
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Rab11fip1
Name: RAB11 family interacting protein 1 (class I)
Synonyms: 2010200K21Rik, 4833414G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75767
Homologene: 11853
Arhgef38
Name: Rho guanine nucleotide exchange factor (GEF) 38
Synonyms: 9130221D24Rik, D630013G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77669
Homologene: 137396
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71310
Homologene: 57079
Cacna1i
Name: calcium channel, voltage-dependent, alpha 1I subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239556
HGNC: HGNC:1396
Homologene: 69331
Fam38b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Scarf1
Name: scavenger receptor class F, member 1
Synonyms: SREC, SREC-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380713
Homologene: 2741
Lipn
Name: lipase, family member N
Synonyms: 2210418G03Rik, Lipl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70166
Homologene: 66969
Cacnb2
Name: calcium channel, voltage-dependent, beta 2 subunit
Synonyms: Cchb2, Cavbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12296
HGNC: HGNC:1402
Homologene: 75191
Aldh1a7
Name: aldehyde dehydrogenase family 1, subfamily A7
Synonyms: Aldh-pb, Ahd2-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 26358
HGNC: HGNC:402
Homologene: 137245
Kif26b
Name: kinesin family member 26B
Synonyms: N-11 kinesin, D230039L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269152
Homologene: 18623
Trim47
Name: tripartite motif-containing 47
Synonyms: 2210023F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217333
Homologene: 14128
Slc6a21
Name: solute carrier family 6 member 21
Synonyms: 1700039E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76713
Homologene: 66347
Pdzd7
Name: PDZ domain containing 7
Synonyms: Pdzk7, EG435601
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100503041
Homologene: 129509
Zfp777
Name: zinc finger protein 777
Synonyms: 2500002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72306
Homologene: 56721
Vcam1
Name: vascular cell adhesion molecule 1
Synonyms: CD106, Vcam-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22329
Homologene: 838
Vmn2r17
Name: vomeronasal 2, receptor 17
Synonyms: EG384221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 384221
Homologene: 104825
Kics2
Name: KICSTOR subunit 2
Synonyms: BC048403
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 270802
Homologene: 17580
Lypd10
Name: Ly6/PLAUR domain containing 10
Synonyms: BC049730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232972
Piwil4
Name: piwi-like RNA-mediated gene silencing 4
Synonyms: 9230101H05Rik, Miwi2, MIWI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330890
Homologene: 45122
Tekt1
Name: tektin 1
Synonyms: MT14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21689
Homologene: 7973
Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Synonyms: 1alpha(OH)ase, P450VD1alpha, 25-hydroxyvitamin D3 1alpha-hydroxylase, 25(OH)D 1alpha-hydroxylase, Pddr, Cyp1, Cp2b, Cyp40, VddrI, P450c1, Cyp27b, Vddr, Vdd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13115
HGNC: HGNC:2606
Homologene: 37139
Zp1
Name: zona pellucida glycoprotein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 22786
Homologene: 33483
Gtsf1
Name: gametocyte specific factor 1
Synonyms: Cue110, 1700006H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74174
Homologene: 16942
Or14j5
Name: olfactory receptor family 14 subfamily J member 5
Synonyms: MOR218-1, GA_x6K02T2PSCP-2307164-2308123, Olfr126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258892
Homologene: 134080
Cblc
Name: Casitas B-lineage lymphoma c
Synonyms: Cbl3, 2310079L19Rik, 2310076I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80794
Homologene: 8108
Med22
Name: mediator complex subunit 22
Synonyms: Surf-5, Surf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20933
Homologene: 4913
Vmn1r16
Name: vomeronasal 1 receptor 16
Synonyms: V1rc29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171202
Homologene: 123821
Or14c44
Name: olfactory receptor family 14 subfamily C member 44
Synonyms: GA_x6K02T2NHDJ-9693313-9692378, MOR221-1P, MOR211-8P, MOR221-1P, MOR221-4, Olfr1531-ps1, Olfr301
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257958
Homologene: 128067
Mapk7
Name: mitogen-activated protein kinase 7
Synonyms: ERK5, BMK1, big MAP kinase 1, Erk5-T, b2b2346Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23939
HGNC: HGNC:6880
Homologene: 2060
BC007180
Name: cDNA sequence BC007180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Sco1
Name: SCO1 cytochrome c oxidase assembly protein
Synonyms: 2610001C07Rik, D11Bwg1310e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52892
Homologene: 3374
Cyb5d2
Name: cytochrome b5 domain containing 2
Synonyms: 9330151E16Rik, neuferricin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192986
Homologene: 14701
Otud1
Name: OTU domain containing 1
Synonyms: 4933428L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71198
Homologene: 45953
I830134H01Rik
Name: RIKEN cDNA I830134H01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 11,156,364 bp
  • G to A, chromosome 1 at 65,244,420 bp
  • A to G, chromosome 1 at 74,686,391 bp
  • G to A, chromosome 1 at 106,392,597 bp
  • GAAA to GAA, chromosome 1 at 178,916,616 bp
  • A to G, chromosome 2 at 5,229,142 bp
  • A to T, chromosome 2 at 14,981,425 bp
  • G to C, chromosome 2 at 19,658,140 bp
  • A to G, chromosome 2 at 26,910,367 bp
  • T to G, chromosome 2 at 160,754,437 bp
  • T to C, chromosome 3 at 116,114,491 bp
  • A to G, chromosome 3 at 122,426,649 bp
  • T to C, chromosome 3 at 133,206,925 bp
  • T to A, chromosome 3 at 135,849,133 bp
  • G to A, chromosome 3 at 154,762,361 bp
  • T to C, chromosome 4 at 9,844,568 bp
  • T to A, chromosome 5 at 109,428,396 bp
  • A to G, chromosome 6 at 8,097,014 bp
  • A to G, chromosome 6 at 11,933,874 bp
  • G to T, chromosome 6 at 28,531,404 bp
  • T to C, chromosome 6 at 48,044,215 bp
  • A to G, chromosome 6 at 57,323,227 bp
  • T to C, chromosome 7 at 19,792,172 bp
  • T to A, chromosome 7 at 24,714,287 bp
  • T to C, chromosome 7 at 45,282,714 bp
  • A to T, chromosome 7 at 86,413,193 bp
  • G to A, chromosome 8 at 27,152,746 bp
  • A to G, chromosome 8 at 83,233,663 bp
  • T to C, chromosome 9 at 6,359,762 bp
  • T to C, chromosome 9 at 14,739,466 bp
  • T to C, chromosome 9 at 15,069,748 bp
  • G to C, chromosome 9 at 35,566,578 bp
  • A to C, chromosome 9 at 42,339,033 bp
  • T to C, chromosome 9 at 56,258,383 bp
  • T to C, chromosome 10 at 76,711,117 bp
  • T to C, chromosome 10 at 121,745,316 bp
  • G to T, chromosome 10 at 127,051,060 bp
  • A to T, chromosome 11 at 35,688,682 bp
  • T to C, chromosome 11 at 46,261,506 bp
  • A to G, chromosome 11 at 61,489,854 bp
  • T to C, chromosome 11 at 67,053,779 bp
  • T to C, chromosome 11 at 72,354,819 bp
  • G to T, chromosome 11 at 72,795,523 bp
  • T to C, chromosome 11 at 75,515,252 bp
  • T to C, chromosome 11 at 116,107,957 bp
  • C to A, chromosome 12 at 64,951,421 bp
  • CCTTTGCGCTT to CCTT, chromosome 15 at 47,741,236 bp
  • T to C, chromosome 15 at 80,356,187 bp
  • A to C, chromosome 15 at 94,331,458 bp
  • T to C, chromosome 15 at 103,425,475 bp
  • T to A, chromosome 17 at 13,896,174 bp
  • T to C, chromosome 17 at 37,851,180 bp
  • A to G, chromosome 18 at 63,081,662 bp
  • T to C, chromosome 19 at 10,916,524 bp
  • T to C, chromosome 19 at 20,708,238 bp
  • T to C, chromosome 19 at 34,069,533 bp
  • A to G, chromosome 19 at 38,053,112 bp
  • A to T, chromosome 19 at 45,040,254 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3832 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040887-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.