Strain Name:
C57BL/6J-MtgxR3932Btlr/Mmmh
Stock Number:
040919-MU
Citation ID:
RRID:MMRRC_040919-MU
Other Names:
R3932 (G1), C57BL/6J-MtgxR3932Btlr
Major Collection:

Gene Information

Rgs9
Name: regulator of G-protein signaling 9
Synonyms: RGS9-1, Rgs9-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19739
Homologene: 2845
Odc1
Name: ornithine decarboxylase, structural 1
Synonyms: ODC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18263
VEGA: 12
HGNC: HGNC:8109
Homologene: 1906
Grin3a
Name: glutamate receptor ionotropic, NMDA3A
Synonyms: A830097C19Rik, NMDAR-L, NR3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242443
Homologene: 128613
Rubcn
Name: RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
Synonyms: 1700021K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 100502698
Homologene: 15687
Arl1
Name: ADP-ribosylation factor-like 1
Synonyms: 2310008D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 104303
HGNC: HGNC:692
Homologene: 20319
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: GCN1L, G431004K08Rik, Gcn1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Mbtd1
Name: mbt domain containing 1
Synonyms: hemp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103537
Homologene: 41185
Opa1
Name: OPA1, mitochondrial dynamin like GTPase
Synonyms: 1200011N24Rik, optic atrophy 1, lilr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74143
HGNC: HGNC:8140
Homologene: 14618
Clcc1
Name: chloride channel CLIC-like 1
Synonyms: Mclc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229725
Homologene: 9032
Rag1
Name: recombination activating 1
Synonyms: Rag-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19373
HGNC: HGNC:9831
Homologene: 387
Coch
Name: cochlin
Synonyms: D12H14S564E, Coch-5B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12810
VEGA: 12
HGNC: HGNC:2180
Homologene: 20868
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: Pcn, Plc, perlecan, per
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Pdcd1
Name: programmed cell death 1
Synonyms: PD-1, Pdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18566
HGNC: HGNC:8760
Homologene: 3681
Atp10a
Name: ATPase, class V, type 10A
Synonyms: pfatp, Atp10c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11982
Homologene: 56461
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 545260
Homologene: 44428
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: MIBP1, Gm20114, Shn-2, Schnurri-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Pde5a
Name: phosphodiesterase 5A, cGMP-specific
Synonyms: Pde5, PDE5A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242202
HGNC: HGNC:8784
Homologene: 842
Nav3
Name: neuron navigator 3
Synonyms: 9630020C08Rik, Pomfil1p, 4732483H20Rik, unc53H3, steerin 3, POMFIL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 260315
Homologene: 56688
Fam135b
Name: family with sequence similarity 135, member B
Synonyms: A830008O07Rik, 1700010C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 70363
VEGA: 15
Homologene: 66605
Tubgcp6
Name: tubulin, gamma complex associated protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 328580
Homologene: 32477
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: VR16, V2r16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22307
Homologene: 129606
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: beta3B, Naptb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
BC051142
Name: cDNA sequence BC051142
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 407788
Homologene: 128168
Frmd4a
Name: FERM domain containing 4A
Synonyms: 2700017I06Rik, C230040M21Rik, Gm13190
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 209630
Homologene: 9971
Vmn2r85
Name: vomeronasal 2, receptor 85
Synonyms: EG623734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 623734
Homologene: 129606
Fbxw10
Name: F-box and WD-40 domain protein 10
Synonyms: SM2SH2, SM25H2, Fbw10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 213980
Homologene: 32757
Tmem94
Name: transmembrane protein 94
Synonyms: 2310067B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71947
Homologene: 8831
Mgat4b
Name: mannoside acetylglucosaminyltransferase 4, isoenzyme B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103534
HGNC: HGNC:7048
Homologene: 8611
Slc13a2
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
Synonyms: sodium/dicarboxylate co-transporter, Nadc1, mNaDC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20500
Homologene: 2965
Rin3
Name: Ras and Rab interactor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217835
Homologene: 11748
Edar
Name: ectodysplasin-A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13608
HGNC: HGNC:2895
Homologene: 7699
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20684
Homologene: 86761
Ctdnep1
Name: CTD nuclear envelope phosphatase 1
Synonyms: 2610507E10Rik, Dullard
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67181
Homologene: 9100
Med10
Name: mediator complex subunit 10
Synonyms: D13Wsu50e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 28077
VEGA: 13
Homologene: 44533
Zfp422
Name: zinc finger protein 422
Synonyms: KOX15, Krox25, Krox-25-2, Krox26, Krox-26, 2900028O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67255
Homologene: 5067
Plin4
Name: perilipin 4
Synonyms: S3-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 57435
Homologene: 69311
Mrc2
Name: mannose receptor, C type 2
Synonyms: Endo180, novel lectin, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17534
Homologene: 4408
Nfe2l3
Name: nuclear factor, erythroid derived 2, like 3
Synonyms: Nrf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18025
HGNC: HGNC:7783
Homologene: 3168
Morn5
Name: MORN repeat containing 5
Synonyms: 1700010A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75495
Homologene: 16510
Olfr1444
Name: olfactory receptor 1444
Synonyms: MOR202-4, GA_x6K02T2RE5P-3191201-3192160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258697
Homologene: 64906
Myrf
Name: myelin regulatory factor
Synonyms: LOC386531, LOC225908, Gm98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Fam184a
Name: family with sequence similarity 184, member A
Synonyms: 4930589M24Rik, 3110012E06Rik, 4930438C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75906
Homologene: 11600
H2-Q6
Name: histocompatibility 2, Q region locus 6
Synonyms: H-2Q6, Qa-6, 0610037M15Rik, Qa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 110557
HGNC: HGNC:4931
Homologene: 128352
Rgs7bp
Name: regulator of G-protein signalling 7 binding protein
Synonyms: D13Bwg1146e, A930030I01Rik, R7bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 52882
VEGA: 13
Homologene: 78705
Zfp94
Name: zinc finger protein 94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22756
Homologene: 86846
Bcl2l14
Name: BCL2-like 14 (apoptosis facilitator)
Synonyms: 4930452K23Rik, 4933405K19Rik, 9030625M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 66813
Homologene: 49840
Tfec
Name: transcription factor EC
Synonyms: bHLHe34, Tcfec, TFEC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 21426
Homologene: 32148
Cdc34b
Name: cell division cycle 34B
Synonyms: Cdc34-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 111266
Tmem28
Name: transmembrane protein 28
Synonyms: EG620592, Fam155b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 620592
Homologene: 83276
Msl3
Name: MSL complex subunit 3
Synonyms: Msl31, Msl3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 17692
HGNC: HGNC:7370
Homologene: 40749
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 85,665,264 bp
  • T to C, chromosome 1 at 94,041,264 bp
  • T to C, chromosome 2 at 4,537,260 bp
  • C to A, chromosome 2 at 36,053,023 bp
  • T to C, chromosome 2 at 101,643,039 bp
  • T to C, chromosome 3 at 108,673,366 bp
  • G to A, chromosome 3 at 122,760,896 bp
  • C to T, chromosome 4 at 49,672,472 bp
  • T to C, chromosome 4 at 137,515,568 bp
  • C to A, chromosome 5 at 109,002,222 bp
  • A to G, chromosome 5 at 115,587,834 bp
  • T to A, chromosome 6 at 16,845,459 bp
  • A to G, chromosome 6 at 51,456,615 bp
  • T to C, chromosome 6 at 116,626,459 bp
  • A to G, chromosome 6 at 134,423,808 bp
  • T to G, chromosome 7 at 24,303,687 bp
  • T to C, chromosome 7 at 58,827,104 bp
  • C to T, chromosome 7 at 81,473,850 bp
  • C to A, chromosome 10 at 14,128,969 bp
  • C to T, chromosome 10 at 53,699,301 bp
  • C to T, chromosome 10 at 58,610,342 bp
  • C to T, chromosome 10 at 88,733,536 bp
  • T to C, chromosome 10 at 92,829,757 bp
  • T to A, chromosome 10 at 109,694,035 bp
  • T to C, chromosome 10 at 130,418,467 bp
  • T to A, chromosome 11 at 50,233,338 bp
  • A to G, chromosome 11 at 62,869,157 bp
  • A to G, chromosome 11 at 69,989,574 bp
  • T to A, chromosome 11 at 78,398,400 bp
  • T to A, chromosome 11 at 93,921,353 bp
  • G to A, chromosome 11 at 94,742,615 bp
  • G to A, chromosome 11 at 105,348,431 bp
  • A to G, chromosome 11 at 109,275,813 bp
  • T to C, chromosome 11 at 115,789,254 bp
  • T to A, chromosome 12 at 17,548,800 bp
  • T to C, chromosome 12 at 51,603,338 bp
  • A to G, chromosome 12 at 102,390,083 bp
  • A to G, chromosome 13 at 69,809,982 bp
  • T to C, chromosome 13 at 105,052,998 bp
  • T to A, chromosome 15 at 71,450,431 bp
  • A to G, chromosome 15 at 89,104,414 bp
  • A to T, chromosome 16 at 29,610,880 bp
  • A to G, chromosome 16 at 32,829,259 bp
  • A to G, chromosome 17 at 34,443,443 bp
  • C to T, chromosome 17 at 35,425,566 bp
  • A to G, chromosome 17 at 56,106,704 bp
  • G to A, chromosome 18 at 60,916,651 bp
  • T to C, chromosome 19 at 10,218,151 bp
  • T to C, chromosome 19 at 12,862,630 bp
  • G to A, chromosome X at 99,821,864 bp
  • C to T, chromosome X at 168,671,817 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3932 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040919-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.