Strain Name:
C57BL/6J-MtgxR4108Btlr/Mmmh
Stock Number:
040987-MU
Citation ID:
RRID:MMRRC_040987-MU
Other Names:
R4108 (G1), C57BL/6J-MtgxR4108Btlr
Major Collection:

Gene Information

Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20269
Homologene: 56005
Sult6b1
Name: sulfotransferase family, cytosolic, 6B, member 1
Synonyms: 2410078J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73671
Homologene: 42242
Vps54
Name: VPS54 GARP complex subunit
Synonyms: wr, Vps54l, 5330404P15Rik, mSLP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 245944
Homologene: 5605
Dtx4
Name: deltex 4, E3 ubiquitin ligase
Synonyms: RNF155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 207521
VEGA: 19
Homologene: 27781
Plxnd1
Name: plexin D1
Synonyms: b2b553Clo, 6230425C21Rik, b2b1863Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Nfya
Name: nuclear transcription factor-Y alpha
Synonyms: Sez10, Cbf-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18044
HGNC: HGNC:7804
Homologene: 32114
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, A330063D19Rik, 9030205D12Rik, AD013
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109151
Homologene: 11844
Tbcd
Name: tubulin-specific chaperone d
Synonyms: A030005L14Rik, 2310057L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 108903
Homologene: 4368
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, mitosin, Lek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Psmb7
Name: proteasome (prosome, macropain) subunit, beta type 7
Synonyms: MC14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19177
HGNC: HGNC:9544
Homologene: 2093
Supt16
Name: SPT16, facilitates chromatin remodeling subunit
Synonyms: Spt16, Cdc68, Fact140, Supt16h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 114741
VEGA: 14
Homologene: 5207
Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Synonyms: ELP, adrenal 4-binding protein, steroidogenic factor 1, SF-1, SF1, Ad4BP, Ftzf1, Ftz-F1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 26423
HGNC: HGNC:7983
Homologene: 3638
Tsg101
Name: tumor susceptibility gene 101
Synonyms: CC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22088
Homologene: 4584
Sbf1
Name: SET binding factor 1
Synonyms: B230113C15Rik, 2610510A08Rik, Mtmr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 77980
Homologene: 84710
Setd1a
Name: SET domain containing 1A
Synonyms: KMT2F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233904
Homologene: 52251
Leprotl1
Name: leptin receptor overlapping transcript-like 1
Synonyms: 1110067H13Rik, 1520402O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 68192
HGNC: HGNC:6555
Homologene: 41031
Ncstn
Name: nicastrin
Synonyms: 9430068N19Rik, Nct, D1Dau13e, nicastrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 59287
Homologene: 41029
Ppp1r12c
Name: protein phosphatase 1, regulatory subunit 12C
Synonyms: 2410197A17Rik, Mbs85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232807
Homologene: 75071
Dnajb2
Name: DnaJ heat shock protein family (Hsp40) member B2
Synonyms: Dnajb10, 2700059H22Rik, mDj8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 56812
HGNC: HGNC:5228
Homologene: 4902
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319670
VEGA: 12
Homologene: 26807
Prss22
Name: protease, serine 22
Synonyms: 4733401N09Rik, SP001LA, BSSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 70835
VEGA: 17
Homologene: 23344
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: nmf112, sals, 4930542A03Rik, bob, mdfw, USH1D, ahl, nmf252, nmf181
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22295
Homologene: 11142
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Col1a-2, Cola-2, Cola2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Bmper
Name: BMP-binding endothelial regulator
Synonyms: CV-2, crossveinless-2, Crim3, 3110056H04Rik, Cv2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 73230
VEGA: 9
Homologene: 12494
Ccr7
Name: chemokine (C-C motif) receptor 7
Synonyms: Cmkbr7, Ebi1h, CD197, EBI1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12775
HGNC: HGNC:1608
Homologene: 1387
Ttn
Name: titin
Synonyms: D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, mdm, 1100001C23Rik, shru, connectin, L56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71985
Homologene: 49825
Pik3c2g
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18705
HGNC: HGNC:8973
Homologene: 3362
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna1, Spna-1, ihj, erythroid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20739
Homologene: 74460
4930579F01Rik
Name: RIKEN cDNA 4930579F01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67741
Homologene: 12962
Cyp2j7
Name: cytochrome P450, family 2, subfamily j, polypeptide 7
Synonyms: OTTMUSG00000007941, Cyp2j7-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 546837
Nfatc1
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Synonyms: NF-ATc, NFAT2, 2210017P03Rik, NFATc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 18018
VEGA: 18
HGNC: HGNC:7775
Homologene: 32336
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20192
Homologene: 68151
Tpo
Name: thyroid peroxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 22018
Homologene: 461
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: MyHC-IId/x, IId/x, IId, myosin heavy chain 2X, MYHC-IIX, Myhsf2, Myhs-f2, A530084A17Rik, Myhs-f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Caskin1
Name: CASK interacting protein 1
Synonyms: C630036E02Rik, 3300002N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268932
VEGA: 17
Homologene: 25873
Slc15a2
Name: solute carrier family 15 (H+/peptide transporter), member 2
Synonyms: 8430408C16Rik, Pept2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 57738
Homologene: 56912
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628870
Homologene: 46008
Ush1c
Name: USH1 protein network component harmonin
Synonyms: Usher syndrome 1C, 2010016F01Rik, harmonin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72088
Homologene: 77476
Slc34a2
Name: solute carrier family 34 (sodium phosphate), member 2
Synonyms: NaPi-2b, D5Ertd227e, type IIb Na/Picotransporter, Npt2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20531
Homologene: 2297
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237711
Homologene: 104282
Ccndbp1
Name: cyclin D-type binding-protein 1
Synonyms: Maid, SSEC-8, DIP1, stage specific embryonic cDNA-8, GCIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17151
HGNC: HGNC:1587
Homologene: 7826
Kif26b
Name: kinesin family member 26B
Synonyms: N-11 kinesin, D230039L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269152
Homologene: 18623
Fsd2
Name: fibronectin type III and SPRY domain containing 2
Synonyms: Spryd1, 9830160G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244091
Homologene: 18252
Rad51ap2
Name: RAD51 associated protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 209550
VEGA: 12
Homologene: 85245
Nfe2l1
Name: nuclear factor, erythroid derived 2,-like 1
Synonyms: TCF-11, Lcrf1, LCR-F1, TCF11, NRF1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18023
HGNC: HGNC:7781
Homologene: 20685
1700113H08Rik
Name: RIKEN cDNA 1700113H08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 76640
Homologene: 45695
Arhgap31
Name: Rho GTPase activating protein 31
Synonyms: CdGAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12549
Homologene: 10644
Smtn
Name: smoothelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 29856
Homologene: 8482
Inf2
Name: inverted formin, FH2 and WH2 domain containing
Synonyms: 2610204M08Rik, EG629699
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 70435
VEGA: 12
Homologene: 82406
Phc2
Name: polyhomeotic 2
Synonyms: D4Ertd810e, Mph2, Edr2, D130050K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54383
HGNC: HGNC:3183
Homologene: 75090
Olfr11
Name: olfactory receptor 11
Synonyms: MOR256-11, GA_x6K02T2QHY8-11597382-11598323
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218066
HGNC: HGNC:8241
Homologene: 40838
Scrn2
Name: secernin 2
Synonyms: D11Moh48, SES2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217140
Homologene: 26698
Atp4b
Name: ATPase, H+/K+ exchanging, beta polypeptide
Synonyms: H+/K+-ATPase beta, H,K-ATPase-Beta, H+,K+-ATPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11945
HGNC: HGNC:820
Homologene: 20182
Cyb5r2
Name: cytochrome b5 reductase 2
Synonyms: D630003K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320635
Homologene: 6182
Olfr844
Name: olfactory receptor 844
Synonyms: MOR153-3, GA_x6K02T2PVTD-13056760-13057689
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100503048
Ubald1
Name: UBA-like domain containing 1
Synonyms: 1500031H01Rik, Fam100a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207740
Homologene: 17055
Acox3
Name: acyl-Coenzyme A oxidase 3, pristanoyl
Synonyms: pristanoyl-CoA oxidase, PCOX, EST-s59
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 80911
HGNC: HGNC:121
Homologene: 37792
Rpl12
Name: ribosomal protein L12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269261
Homologene: 128047
Pou4f3
Name: POU domain, class 4, transcription factor 3
Synonyms: Brn-3.1, Brn3.1, Brn3c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 18998
HGNC: HGNC:9220
Homologene: 2023
Vmn2r-ps159
Name: vomeronasal 2, receptor, pseudogene 159
Synonyms: V2r9, Vmn2r-ps160, V2r8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22314
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 75,236,899 bp
  • G to T, chromosome 1 at 172,072,544 bp
  • A to G, chromosome 1 at 174,174,556 bp
  • A to G, chromosome 1 at 178,916,965 bp
  • A to G, chromosome 1 at 189,683,868 bp
  • C to A, chromosome 2 at 32,961,823 bp
  • A to T, chromosome 2 at 32,961,824 bp
  • T to A, chromosome 2 at 38,642,199 bp
  • T to C, chromosome 2 at 38,702,069 bp
  • A to G, chromosome 2 at 40,665,087 bp
  • A to G, chromosome 2 at 65,495,035 bp
  • G to C, chromosome 2 at 76,750,871 bp
  • C to T, chromosome 2 at 76,778,465 bp
  • C to G, chromosome 2 at 112,675,873 bp
  • T to C, chromosome 2 at 121,011,731 bp
  • T to C, chromosome 3 at 138,183,670 bp
  • T to C, chromosome 4 at 96,199,450 bp
  • A to G, chromosome 4 at 128,707,983 bp
  • G to T, chromosome 4 at 156,334,397 bp
  • T to C, chromosome 5 at 35,601,552 bp
  • G to A, chromosome 5 at 53,064,009 bp
  • G to T, chromosome 5 at 121,631,464 bp
  • G to A, chromosome 6 at 4,518,822 bp
  • G to T, chromosome 6 at 115,959,315 bp
  • C to A, chromosome 6 at 139,730,370 bp
  • T to C, chromosome 7 at 4,486,566 bp
  • C to T, chromosome 7 at 46,198,445 bp
  • T to A, chromosome 7 at 46,892,494 bp
  • C to T, chromosome 7 at 81,544,967 bp
  • A to T, chromosome 7 at 107,753,929 bp
  • G to A, chromosome 7 at 127,799,202 bp
  • A to G, chromosome 8 at 13,396,640 bp
  • A to G, chromosome 8 at 34,140,759 bp
  • A to T, chromosome 8 at 91,010,676 bp
  • T to A, chromosome 9 at 19,319,312 bp
  • G to A, chromosome 9 at 23,224,763 bp
  • C to A, chromosome 10 at 60,410,822 bp
  • A to G, chromosome 10 at 87,225,934 bp
  • C to T, chromosome 10 at 107,771,244 bp
  • G to A, chromosome 11 at 3,526,449 bp
  • A to G, chromosome 11 at 21,312,877 bp
  • A to C, chromosome 11 at 29,805,136 bp
  • T to C, chromosome 11 at 59,131,646 bp
  • T to C, chromosome 11 at 67,211,577 bp
  • C to T, chromosome 11 at 96,819,394 bp
  • T to C, chromosome 11 at 97,032,144 bp
  • C to T, chromosome 11 at 99,145,378 bp
  • T to A, chromosome 11 at 121,493,811 bp
  • T to C, chromosome 12 at 11,458,395 bp
  • G to A, chromosome 12 at 30,092,586 bp
  • T to C, chromosome 12 at 98,841,548 bp
  • T to C, chromosome 12 at 112,607,581 bp
  • A to G, chromosome 13 at 21,638,782 bp
  • T to C, chromosome 14 at 52,162,731 bp
  • T to C, chromosome 15 at 89,288,585 bp
  • C to A, chromosome 16 at 4,875,867 bp
  • G to T, chromosome 16 at 36,782,393 bp
  • A to G, chromosome 16 at 38,602,426 bp
  • A to G, chromosome 17 at 23,993,873 bp
  • C to A, chromosome 17 at 24,502,147 bp
  • G to T, chromosome 17 at 48,392,884 bp
  • G to T, chromosome 17 at 78,906,862 bp
  • A to G, chromosome 18 at 42,395,922 bp
  • T to A, chromosome 18 at 80,698,368 bp
  • G to A, chromosome 19 at 12,501,123 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4108 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040987-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.