Strain Name:
C57BL/6J-MtgxR4580Btlr/Mmmh
Stock Number:
041599-MU
Citation ID:
RRID:MMRRC_041599-MU
Other Names:
R4580 (G1), C57BL/6J-MtgxR4580Btlr
Major Collection:

Gene Information

Ifngr2
Name: interferon gamma receptor 2
Synonyms: Ifgt, Ifgr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15980
HGNC: HGNC:5440
Homologene: 4041
Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20349
Homologene: 8247
Nrcam
Name: neuronal cell adhesion molecule
Synonyms: Bravo, C030017F07Rik, C130076O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319504
VEGA: 12
HGNC: HGNC:7994
Homologene: 21041
Pmpca
Name: peptidase (mitochondrial processing) alpha
Synonyms: INPP5E, Alpha-MPP, 4933435E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66865
Homologene: 6078
Efr3a
Name: EFR3 homolog A
Synonyms: A130089M23Rik, D030063F01Rik, C920006C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76740
Homologene: 44222
Stk11ip
Name: serine/threonine kinase 11 interacting protein
Synonyms: LKB1IP, LIP1, 1200014D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71728
Homologene: 12406
Golga4
Name: golgi autoantigen, golgin subfamily a, 4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Usp32
Name: ubiquitin specific peptidase 32
Synonyms: 6430526O11Rik, 2900074J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237898
Homologene: 13066
Mast4
Name: microtubule associated serine/threonine kinase family member 4
Synonyms: 4930420O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328329
Homologene: 42094
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Tcf7l2
Name: transcription factor 7 like 2, T cell specific, HMG box
Synonyms: TCF4E, TCF4B, mTcf-4E, mTcf-4B, Tcf-4, Tcf4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21416
Homologene: 7564
Lmtk2
Name: lemur tyrosine kinase 2
Synonyms: 2900041G10Rik, KPI-2, cprk, KPI2, A330101P12Rik, BREK, AATYK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231876
Homologene: 8948
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Myo9b
Name: myosin IXb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Bub1
Name: BUB1, mitotic checkpoint serine/threonine kinase
Synonyms: Bub1a, D2Xrf87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12235
HGNC: HGNC:1148
Homologene: 37910
Nrf1
Name: nuclear respiratory factor 1
Synonyms: D6Ertd415e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18181
HGNC: HGNC:7996
Homologene: 3674
Vps39
Name: VPS39 HOPS complex subunit
Synonyms: A230065P22Rik, Vam6P, Vam6, mVam6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269338
Homologene: 41025
Acy1
Name: aminoacylase 1
Synonyms: Acy-1, 1110014J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109652
HGNC: HGNC:177
Homologene: 110440
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230249
Homologene: 6056
Ptprc
Name: protein tyrosine phosphatase, receptor type, C
Synonyms: T200, B220, CD45, Lyt-4, Ly-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 386750
Homologene: 8955
Mpzl3
Name: myelin protein zero-like 3
Synonyms: 5430427F17Rik, rc, A530065I17Rik, ruf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319742
Homologene: 18867
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Maea
Name: macrophage erythroblast attacher
Synonyms: 1110030D19Rik, Gid9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 59003
Homologene: 4298
Atp6v1g1
Name: ATPase, H+ transporting, lysosomal V1 subunit G1
Synonyms: 1810024D14Rik, VAG1, ATP6J, Vma10, Atp6g1, lysosomal 13kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66290
HGNC: HGNC:864
Homologene: 31272
Kif24
Name: kinesin family member 24
Synonyms: 4933425J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109242
Homologene: 52346
Pask
Name: PAS domain containing serine/threonine kinase
Synonyms: Paskin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269224
Homologene: 9038
Mavs
Name: mitochondrial antiviral signaling protein
Synonyms: IPS-1, D430028G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228607
Homologene: 17004
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240255
Homologene: 11265
Marchf11
Name: membrane associated ring-CH-type finger 11
Synonyms: March11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211147
Homologene: 45584
Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Synonyms: Cox-2, cyclooxygenase 2, Pghs2, COX2, prostaglandin G/H synthase, PHS-2, cyclooxygenase-2, PGHS-2, Tis10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19225
HGNC: HGNC:9605
Homologene: 31000
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, D830007G01Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Myh15
Name: myosin, heavy chain 15
Synonyms: EG667772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 667772
VEGA: 16
Homologene: 18929
Large2
Name: LARGE xylosyl- and glucuronyltransferase 2
Synonyms: 5730485C17Rik, Gyltl1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228366
Homologene: 27362
Xpc
Name: xeroderma pigmentosum, complementation group C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22591
Homologene: 3401
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Vmn1r59
Name: vomeronasal 1 receptor 59
Synonyms: V1rd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404284
Homologene: 41799
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: 2810012G08Rik, B230396K10Rik, Cytsb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432572
Homologene: 45157
Henmt1
Name: HEN1 methyltransferase homolog 1 (Arabidopsis)
Synonyms: Hen1, 4921515J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66715
Homologene: 32638
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545874
Homologene: 135915
Grb14
Name: growth factor receptor bound protein 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50915
HGNC: HGNC:4565
Homologene: 3303
Xab2
Name: XPA binding protein 2
Synonyms: 0610041O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67439
Homologene: 5738
Cog2
Name: component of oligomeric golgi complex 2
Synonyms: 1190002B08Rik, 2700012E02Rik, Cog2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76332
HGNC: HGNC:6546
Homologene: 7206
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: NHE3, 9030624O13Rik, NHE-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105243
VEGA: 13
Homologene: 55804
BC005537
Name: cDNA sequence BC005537
Synonyms: 8030460C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 79555
Homologene: 11551
Or4c120
Name: olfactory receptor family 4 subfamily C member 120
Synonyms: GA_x6K02T2Q125-50650037-50649102, MOR233-11, Olfr1225
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258893
Homologene: 17427
Grk4
Name: G protein-coupled receptor kinase 4
Synonyms: A830025H08Rik, Gprk2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14772
HGNC: HGNC:4543
Homologene: 23158
Efcab14
Name: EF-hand calcium binding domain 14
Synonyms: 4732418C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230648
Homologene: 8858
Ighv15-2
Name: immunoglobulin heavy variable V15-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780864
Gm4922
Name: predicted gene 4922
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237300
VEGA: 10
Homologene: 50497
Pcdhb7
Name: protocadherin beta 7
Synonyms: Pcdhb4B, PcdhbG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93878
HGNC: HGNC:8689
Homologene: 87123
Tbc1d4
Name: TBC1 domain family, member 4
Synonyms: 5930406J04Rik, AS160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 210789
Homologene: 45451
Rhbdl3
Name: rhomboid like 3
Synonyms: Ventrhoid, Vrho, Rhbdl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246104
Homologene: 34700
Abcc2
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms: multidrug resistance protein 2, Mrp2, Cmoat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Pgbd1
Name: piggyBac transposable element derived 1
Synonyms: 4921509E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319207
Homologene: 130030
Cdh15
Name: cadherin 15
Synonyms: Cdh14, Mcad, M cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Cobll1
Name: Cobl-like 1
Synonyms: Coblr1, D430044D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319876
Homologene: 8933
Fbxo5
Name: F-box protein 5
Synonyms: Emi1, 2510044I10Rik, Fbxo31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67141
Homologene: 8135
Zfp62
Name: zinc finger protein 62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22720
Homologene: 40686
Ccdc162
Name: coiled-coil domain containing 162
Synonyms: 5033413D22Rik, Gm29096, Gm6976
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 75973
Homologene: 136355
Creb5
Name: cAMP responsive element binding protein 5
Synonyms: D430026C09Rik, Crebpa, 9430076C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 231991
Homologene: 18215
Pdp2
Name: pyruvate dehydrogenase phosphatase catalytic subunit 2
Synonyms: LOC382051, 4833426J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382051
Homologene: 36388
Nt5c3b
Name: 5'-nucleotidase, cytosolic IIIB
Synonyms: 2610037D24Rik, C330027I04Rik, Nt5c3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68106
Homologene: 41684
Lrfn3
Name: leucine rich repeat and fibronectin type III domain containing 3
Synonyms: A530045B06Rik, SALM4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233067
Homologene: 11558
Plk5
Name: polo like kinase 5
Synonyms: 6330514A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216166
Homologene: 28072
Trim30d
Name: tripartite motif-containing 30D
Synonyms: TRIM30-3, Trim79
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 209387
Homologene: 114426
Zscan4d
Name: zinc finger and SCAN domain containing 4D
Synonyms: EG545913
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 545913
Homologene: 85986
Prl3b1
Name: prolactin family 3, subfamily b, member 1
Synonyms: Pl-2, Pl2, mplII, PL, prolactin-like, Csh2, mPL-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18776
HGNC: HGNC:9445
Homologene: 7476
Esd
Name: esterase D/formylglutathione hydrolase
Synonyms: Es-10, Esd, Es10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13885
HGNC: HGNC:3465
Homologene: 55623
Slc17a1
Name: solute carrier family 17 (sodium phosphate), member 1
Synonyms: Npt1, NAPI-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20504
Homologene: 48324
Cpeb4
Name: cytoplasmic polyadenylation element binding protein 4
Synonyms: 4930447D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67579
Homologene: 12736
Nphp1
Name: nephronophthisis 1 (juvenile) homolog (human)
Synonyms: nephrocystin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 53885
HGNC: HGNC:7905
Homologene: 229
Tex36
Name: testis expressed 36
Synonyms: 4930404H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73808
Homologene: 67014
Smim35
Name: small integral membrane protein 35
Synonyms: BC049352
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 408059
Homologene: 136435
2810408A11Rik
Name: RIKEN cDNA 2810408A11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70419
Homologene: 49883
Rbpjl
Name: recombination signal binding protein for immunoglobulin kappa J region-like
Synonyms: RBP-J kappa-like, RBP-L, Rbpsuhl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19668
Homologene: 7512
Myl2
Name: myosin, light polypeptide 2, regulatory, cardiac, slow
Synonyms: MLC-2v, MLC-2, Mlc2v, Mylpc, Gm32672
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17906
HGNC: HGNC:7583
Homologene: 55462
Gm26919
Name: predicted gene, 26919
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Homologene: 134227
Trav6-4
Name: T cell receptor alpha variable 6-4
Synonyms: Gm13945
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100126463
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 75,530,229 bp
  • T to C, chromosome 1 at 93,322,108 bp
  • C to T, chromosome 1 at 138,071,251 bp
  • A to T, chromosome 1 at 150,104,094 bp
  • G to T, chromosome 2 at 26,393,335 bp
  • T to C, chromosome 2 at 64,953,603 bp
  • C to T, chromosome 2 at 65,151,073 bp
  • A to G, chromosome 2 at 76,951,396 bp
  • T to A, chromosome 2 at 89,171,200 bp
  • T to C, chromosome 2 at 92,370,612 bp
  • A to T, chromosome 2 at 120,339,333 bp
  • A to G, chromosome 2 at 127,768,169 bp
  • A to C, chromosome 2 at 127,829,676 bp
  • G to T, chromosome 2 at 131,240,450 bp
  • A to G, chromosome 2 at 164,408,337 bp
  • A to T, chromosome 3 at 37,030,025 bp
  • A to G, chromosome 3 at 73,051,206 bp
  • T to A, chromosome 3 at 108,942,765 bp
  • A to G, chromosome 4 at 41,395,287 bp
  • T to C, chromosome 4 at 58,840,751 bp
  • A to G, chromosome 4 at 63,550,032 bp
  • T to A, chromosome 4 at 115,756,477 bp
  • T to C, chromosome 5 at 14,233,703 bp
  • T to C, chromosome 5 at 33,360,488 bp
  • A to G, chromosome 5 at 34,660,981 bp
  • A to T, chromosome 5 at 122,106,738 bp
  • A to G, chromosome 5 at 144,174,781 bp
  • C to T, chromosome 6 at 30,098,542 bp
  • G to A, chromosome 6 at 53,604,534 bp
  • A to G, chromosome 6 at 91,500,011 bp
  • T to C, chromosome 6 at 123,823,023 bp
  • A to G, chromosome 6 at 130,697,948 bp
  • A to T, chromosome 7 at 5,454,137 bp
  • A to G, chromosome 7 at 11,162,508 bp
  • A to T, chromosome 7 at 30,360,042 bp
  • A to G, chromosome 7 at 46,287,801 bp
  • A to G, chromosome 7 at 104,472,558 bp
  • A to C, chromosome 7 at 133,587,382 bp
  • T to C, chromosome 8 at 3,610,162 bp
  • A to G, chromosome 8 at 71,315,135 bp
  • C to A, chromosome 8 at 104,594,944 bp
  • T to C, chromosome 8 at 122,865,158 bp
  • T to C, chromosome 8 at 124,545,136 bp
  • T to A, chromosome 9 at 45,068,231 bp
  • G to T, chromosome 9 at 45,244,128 bp
  • T to C, chromosome 9 at 106,435,038 bp
  • C to T, chromosome 9 at 110,574,243 bp
  • C to A, chromosome 9 at 118,557,259 bp
  • T to A, chromosome 9 at 122,747,515 bp
  • T to C, chromosome 10 at 5,805,255 bp
  • T to C, chromosome 10 at 18,783,684 bp
  • T to C, chromosome 10 at 41,561,140 bp
  • C to T, chromosome 10 at 80,360,467 bp
  • T to A, chromosome 11 at 31,927,757 bp
  • A to G, chromosome 11 at 49,216,272 bp
  • T to A, chromosome 11 at 62,219,331 bp
  • T to C, chromosome 11 at 69,900,411 bp
  • T to C, chromosome 11 at 80,353,645 bp
  • C to A, chromosome 11 at 85,059,127 bp
  • G to T, chromosome 11 at 100,433,059 bp
  • T to C, chromosome 12 at 44,562,540 bp
  • T to A, chromosome 12 at 114,564,970 bp
  • G to C, chromosome 13 at 21,428,329 bp
  • T to C, chromosome 13 at 23,887,977 bp
  • G to T, chromosome 13 at 24,803,411 bp
  • A to G, chromosome 13 at 27,249,467 bp
  • C to T, chromosome 13 at 74,158,886 bp
  • A to T, chromosome 13 at 102,737,258 bp
  • T to C, chromosome 14 at 53,454,699 bp
  • T to C, chromosome 14 at 74,742,077 bp
  • T to C, chromosome 14 at 101,458,783 bp
  • A to T, chromosome 15 at 26,311,103 bp
  • T to A, chromosome 15 at 65,856,610 bp
  • T to C, chromosome 16 at 49,065,025 bp
  • A to G, chromosome 16 at 91,558,018 bp
  • T to A, chromosome 17 at 30,662,052 bp
  • T to A, chromosome 18 at 37,342,135 bp
  • T to A, chromosome 18 at 44,858,198 bp
  • T to C, chromosome 19 at 43,811,119 bp
  • G to A, chromosome 19 at 55,919,036 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4580 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041599-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.