Strain Name:
C57BL/6J-MtgxR4424Btlr/Mmmh
Stock Number:
041696-MU
Citation ID:
RRID:MMRRC_041696-MU
Other Names:
R4424 (G1), C57BL/6J-MtgxR4424Btlr
Major Collection:

Gene Information

Hfe
Name: homeostatic iron regulator
Synonyms: MR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15216
HGNC: HGNC:4886
Homologene: 88330
Ppp1r16b
Name: protein phosphatase 1, regulatory subunit 16B
Synonyms: ANKRD4, Wdt4, C130078N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228852
Homologene: 9194
Mindy3
Name: MINDY lysine 48 deubiquitinase 3
Synonyms: 1810041E18Rik, 5830410F13Rik, 2310047O13Rik, Fam188a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66960
Homologene: 11478
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alpha-fodrin, Spna-2, 2610027H02Rik, Spna2, alphaII-spectrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20740
Homologene: 2353
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Ppat
Name: phosphoribosyl pyrophosphate amidotransferase
Synonyms: 5730454C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231327
HGNC: HGNC:9238
Homologene: 68272
Mtmr12
Name: myotubularin related protein 12
Synonyms: C730015A02Rik, Pip3ap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268783
Homologene: 10403
Rnmt
Name: RNA (guanine-7-) methyltransferase
Synonyms: 2610002P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67897
Homologene: 2816
Clcn7
Name: chloride channel, voltage-sensitive 7
Synonyms: ClC-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26373
HGNC: HGNC:2025
Homologene: 56546
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Aimp1
Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Synonyms: Emap2, AIMP1/p43, 9830137A06Rik, Scye1, EMAPII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13722
Homologene: 31260
Zbtb40
Name: zinc finger and BTB domain containing 40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230848
Homologene: 8912
Lin54
Name: lin-54 DREAM MuvB core complex component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231506
Homologene: 18212
Arfgap1
Name: ADP-ribosylation factor GTPase activating protein 1
Synonyms: ARF1 GAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228998
Homologene: 5517
Atp5a1
Name: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Synonyms: Atpm, D18Ertd206e, Mom2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11946
HGNC: HGNC:823
Homologene: 2985
Msh6
Name: mutS homolog 6
Synonyms: Msh6, GTBP, Gtmbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17688
VEGA: 17
HGNC: HGNC:7329
Homologene: 149
Syvn1
Name: synovial apoptosis inhibitor 1, synoviolin
Synonyms: Hrd1, 1200010C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74126
Homologene: 32700
Nxf1
Name: nuclear RNA export factor 1
Synonyms: Tip associated protein, TAP, Mex67, Mvb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 53319
HGNC: HGNC:8071
Homologene: 38176
Arid3b
Name: AT rich interactive domain 3B (BRIGHT-like)
Synonyms: Bdp, Dri2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56380
Homologene: 4721
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 252972
Homologene: 9905
Jun
Name: jun proto-oncogene
Synonyms: c-jun, Junc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16476
HGNC: HGNC:6204
Homologene: 1679
Pik3ap1
Name: phosphoinositide-3-kinase adaptor protein 1
Synonyms: BCAP, 1810044J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83490
VEGA: 19
Homologene: 12848
Cep164
Name: centrosomal protein 164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214552
Homologene: 51110
Myo6
Name: myosin VI
Synonyms: Tlc, Myo6rsv, rsv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Zcchc14
Name: zinc finger, CCHC domain containing 14
Synonyms: Bdg29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 142682
Homologene: 9037
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 58178
Homologene: 10967
Glce
Name: glucuronyl C5-epimerase
Synonyms: heparan sulfate-glucuronic acid C5-epimerase, Hsepi, C130034A12Rik, 1110017N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 93683
Homologene: 14111
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Psma8
Name: proteasome subunit alpha 8
Synonyms: 2410072D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 73677
VEGA: 18
Homologene: 2086
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234686
Homologene: 136406
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 105242472
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Dll3
Name: delta like canonical Notch ligand 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13389
HGNC: HGNC:2909
Homologene: 7291
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: MyHC-IIa, MHC2A, Myhs-f1, Myhs-f, Myhsf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Impg2
Name: interphotoreceptor matrix proteoglycan 2
Synonyms: PG10.2, IPM200, Spacrcan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224224
Homologene: 9439
Chrnd
Name: cholinergic receptor, nicotinic, delta polypeptide
Synonyms: Achr-4, Acrd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11447
HGNC: HGNC:1965
Homologene: 37340
Krt78
Name: keratin 78
Synonyms: 2310030B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 332131
VEGA: 15
Homologene: 65261
Mapk12
Name: mitogen-activated protein kinase 12
Synonyms: Sapk3, Erk6, P38gamma, Prkm12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 29857
VEGA: 15
HGNC: HGNC:6874
Homologene: 55705
Shc4
Name: SHC (Src homology 2 domain containing) family, member 4
Synonyms: 9930029B02Rik, LOC271849, 6230417E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271849
Homologene: 19567
4933409G03Rik
Name: RIKEN cDNA 4933409G03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227998
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: 1110061H03Rik, SRRP129, CASP11, SIP1, 2610510E10Rik, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72193
VEGA: 15
Homologene: 37957
Thegl
Name: theg spermatid protein like
Synonyms: 1700023E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71868
Homologene: 128474
Zfp687
Name: zinc finger protein 687
Synonyms: 4931408L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 78266
Homologene: 10827
Ankrd16
Name: ankyrin repeat domain 16
Synonyms: D430029B21Rik, 2810455F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320816
Homologene: 19509
Upf3a
Name: UPF3 regulator of nonsense transcripts homolog A (yeast)
Synonyms: 4930546M19Rik, RENT3A, UPF3, 2600001C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67031
Homologene: 23395
Cyp2c29
Name: cytochrome P450, family 2, subfamily c, polypeptide 29
Synonyms: AHOH, AHOHase, P450-2C, Ahh-1, Ah-2, Cyp2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13095
HGNC: HGNC:2622
Homologene: 117948
Panx2
Name: pannexin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 406218
HGNC: HGNC:8600
Homologene: 14155
Ankrd37
Name: ankyrin repeat domain 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 654824
Homologene: 35347
Dhrs13
Name: dehydrogenase/reductase (SDR family) member 13
Synonyms: 2610209N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70451
Homologene: 64807
Tex47
Name: testis expressed 47
Synonyms: 4921511H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70920
Homologene: 41723
Olfr971
Name: olfactory receptor 971
Synonyms: GA_x6K02T2PVTD-33539896-33540819, MOR171-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258607
VEGA: 9
Homologene: 133635
Galnt2l
Name: polypeptide N-acetylgalactosaminyltransferase 2-like
Synonyms: Gm20388
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Art2b
Name: ADP-ribosyltransferase 2b
Synonyms: Rt6-2, Rt-6, Rt6, ART2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11872
Homologene: 113756
Fpr2
Name: formyl peptide receptor 2
Synonyms: E330010I07Rik, Fpr-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14289
HGNC: HGNC:3827
Homologene: 74395
Hoxd13
Name: homeobox D13
Synonyms: Hox-4.8, spdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15433
HGNC: HGNC:5136
Homologene: 20147
Mrpl41
Name: mitochondrial ribosomal protein L41
Synonyms: MRP-L27, Rpml27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107733
Homologene: 13036
Cstdc3
Name: cystatin domain containing 3
Synonyms: Gm4758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 209324
VEGA: 16
HGNC: HGNC:2481
Homologene: 86375
Apol11b
Name: apolipoprotein L 11b
Synonyms: A330102K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328563
Homologene: 129975
Nrl
Name: neural retina leucine zipper gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18185
VEGA: 14
HGNC: HGNC:8002
Homologene: 4501
Rpl31-ps17
Name: ribosomal protein L31, pseudogene 17
Synonyms: Gm16382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 673582
Csl
Name: citrate synthase like
Synonyms: 1700007H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71832
VEGA: 10
Homologene: 7131
Pcdhga1
Name: protocadherin gamma subfamily A, 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93709
HGNC: HGNC:8696
Homologene: 56824
Ighv1-66
Name: immunoglobulin heavy variable 1-66
Synonyms: Gm16901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380824
Mroh6
Name: maestro heat-like repeat family member 6
Synonyms: Gm19570
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223645
Homologene: 90414
Cfap91
Name: cilia and flagella associated protein 91
Synonyms: Spata26, 4932425I24Rik, Maats1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320214
Homologene: 33470
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 87,195,790 bp
  • T to A, chromosome 2 at 11,784,404 bp
  • A to G, chromosome 2 at 12,348,199 bp
  • T to C, chromosome 2 at 24,974,406 bp
  • T to A, chromosome 2 at 29,988,436 bp
  • C to T, chromosome 2 at 30,029,709 bp
  • A to T, chromosome 2 at 68,615,147 bp
  • A to T, chromosome 2 at 74,669,957 bp
  • G to T, chromosome 2 at 125,652,522 bp
  • C to T, chromosome 2 at 158,757,254 bp
  • C to A, chromosome 2 at 180,981,076 bp
  • G to A, chromosome 3 at 95,009,128 bp
  • A to T, chromosome 3 at 132,667,492 bp
  • A to T, chromosome 4 at 76,102,963 bp
  • A to G, chromosome 4 at 95,050,847 bp
  • A to T, chromosome 4 at 136,998,694 bp
  • G to T, chromosome 5 at 7,305,364 bp
  • A to G, chromosome 5 at 76,915,214 bp
  • T to C, chromosome 5 at 77,054,536 bp
  • G to T, chromosome 5 at 100,446,560 bp
  • T to C, chromosome 5 at 120,542,518 bp
  • T to C, chromosome 7 at 28,296,291 bp
  • T to A, chromosome 7 at 101,579,922 bp
  • C to A, chromosome 8 at 13,796,573 bp
  • A to G, chromosome 8 at 45,997,787 bp
  • T to C, chromosome 8 at 105,337,351 bp
  • G to A, chromosome 8 at 121,651,941 bp
  • A to G, chromosome 8 at 123,288,793 bp
  • A to T, chromosome 9 at 39,840,356 bp
  • A to T, chromosome 9 at 45,779,704 bp
  • A to T, chromosome 9 at 57,833,868 bp
  • A to G, chromosome 9 at 62,060,253 bp
  • A to G, chromosome 9 at 80,288,038 bp
  • T to A, chromosome 10 at 99,758,591 bp
  • A to T, chromosome 11 at 67,192,725 bp
  • G to T, chromosome 11 at 78,037,125 bp
  • T to G, chromosome 11 at 104,736,114 bp
  • C to T, chromosome 12 at 54,701,612 bp
  • A to T, chromosome 12 at 115,593,537 bp
  • A to T, chromosome 13 at 23,706,883 bp
  • A to G, chromosome 14 at 55,501,471 bp
  • G to A, chromosome 14 at 55,522,218 bp
  • T to C, chromosome 15 at 12,230,314 bp
  • G to T, chromosome 15 at 75,892,756 bp
  • A to G, chromosome 15 at 77,637,933 bp
  • G to T, chromosome 15 at 89,068,220 bp
  • A to G, chromosome 15 at 89,145,373 bp
  • G to A, chromosome 15 at 96,418,428 bp
  • T to C, chromosome 15 at 101,947,940 bp
  • A to G, chromosome 16 at 15,773,739 bp
  • G to A, chromosome 16 at 15,836,082 bp
  • A to G, chromosome 16 at 36,312,589 bp
  • G to T, chromosome 16 at 38,320,365 bp
  • G to A, chromosome 16 at 56,260,025 bp
  • C to T, chromosome 17 at 17,893,132 bp
  • T to C, chromosome 17 at 25,160,176 bp
  • T to A, chromosome 17 at 87,990,789 bp
  • T to A, chromosome 18 at 12,519,872 bp
  • A to G, chromosome 18 at 14,721,190 bp
  • T to C, chromosome 18 at 37,662,579 bp
  • A to G, chromosome 18 at 68,311,671 bp
  • T to A, chromosome 18 at 77,780,066 bp
  • C to T, chromosome 19 at 6,049,921 bp
  • A to G, chromosome 19 at 8,766,764 bp
  • G to T, chromosome 19 at 39,287,176 bp
  • G to A, chromosome 19 at 41,375,881 bp
  • G to A, chromosome 19 at 46,269,784 bp
  • T to C, chromosome 19 at 50,378,941 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4424 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041696-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.