Strain Name:
C57BL/6J-MtgxR4616Btlr/Mmmh
Stock Number:
041827-MU
Citation ID:
RRID:MMRRC_041827-MU
Other Names:
R4616 (G1), C57BL/6J-MtgxR4616Btlr
Major Collection:

Gene Information

Casq2
Name: calsequestrin 2
Synonyms: ESTM52, Csq2, cCSQ, cardiac calsequestrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12373
HGNC: HGNC:1513
Homologene: 20330
Gria2
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2)
Synonyms: Glur2, Glur-2, GluR2, GluA2, GluR-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14800
HGNC: HGNC:4572
Homologene: 20225
Sort1
Name: sortilin 1
Synonyms: Ntr3, neurotensin receptor 3, 2900053A11Rik, sortilin, Ntsr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20661
Homologene: 136097
Mfap4
Name: microfibrillar-associated protein 4
Synonyms: 1110007F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76293
HGNC: HGNC:7035
Homologene: 134529
Aopep
Name: aminopeptidase O
Synonyms: ApO, 2010111I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72061
HGNC: HGNC:1361
Homologene: 66273
Psmd3
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Synonyms: Tstap91a, AntP91a, Psd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 22123
HGNC: HGNC:9560
Homologene: 2102
Tbc1d22a
Name: TBC1 domain family, member 22a
Synonyms: D15Ertd781e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223754
VEGA: 15
HGNC: HGNC:1309
Homologene: 105406
Rbm27
Name: RNA binding motif protein 27
Synonyms: Psc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225432
VEGA: 18
Homologene: 35410
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Usp53
Name: ubiquitin specific peptidase 53
Synonyms: mbo, Phxr3, Sp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99526
Homologene: 34521
Clec16a
Name: C-type lectin domain family 16, member A
Synonyms: 4932416N17Rik, curt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74374
Homologene: 71019
Myo9a
Name: myosin IXa
Synonyms: C130068I12Rik, 4732465J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Aldh16a1
Name: aldehyde dehydrogenase 16 family, member A1
Synonyms: 2410004H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69748
Homologene: 34938
Stard5
Name: StAR-related lipid transfer (START) domain containing 5
Synonyms: 18B7-T7(GS), 2310058G22Rik, D7Ertd152e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 170460
Homologene: 11346
Arhgef17
Name: Rho guanine nucleotide exchange factor (GEF) 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 207212
Homologene: 129601
Chn2
Name: chimerin 2
Synonyms: 4930557O16Rik, 1700026N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69993
HGNC: HGNC:1944
Homologene: 31213
Erbb3
Name: erb-b2 receptor tyrosine kinase 3
Synonyms: HER3, Erbb3r, Erbb-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13867
HGNC: HGNC:3431
Homologene: 20457
Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Synonyms: P450-1, cytochrome P450 subfamily I, polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13076
VEGA: 9
HGNC: HGNC:2595
Homologene: 68062
Mtmr4
Name: myotubularin related protein 4
Synonyms: ESTM44, FYVE-DSP2, ZFYVE11, FYVE zinc finger phosphatase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 170749
HGNC: HGNC:7452
Homologene: 3440
Pomgnt1
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase
Synonyms: 0610016I07Rik, 4930467B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68273
Homologene: 9806
Gm7102
Name: predicted gene 7102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 633057
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
Homologene: 55776
Bcl2a1a
Name: B cell leukemia/lymphoma 2 related protein A1a
Synonyms: A1, Hbpa1, Bfl-1, Bcl2a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12044
HGNC: HGNC:991
Homologene: 2988
Dsg3
Name: desmoglein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13512
VEGA: 18
HGNC: HGNC:3050
Homologene: 55513
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80892
Homologene: 23477
Adgrf5
Name: adhesion G protein-coupled receptor F5
Synonyms: 8430401C09Rik, Gpr116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224792
VEGA: 17
Homologene: 9065
Mrgbp
Name: MRG/MORF4L binding protein
Synonyms: 1600027N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 73247
Homologene: 10104
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC5A, PC6, PC5/6A, b2b585Clo, b2b1549Clo, SPC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Olfr594
Name: olfactory receptor 594
Synonyms: GA_x6K02T2PBJ9-5935234-5936169, MOR32-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258246
Homologene: 17480
Gpld1
Name: glycosylphosphatidylinositol specific phospholipase D1
Synonyms: 6330541J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14756
HGNC: HGNC:4459
Homologene: 1152
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: Spnb5, EG640524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 640524
Homologene: 41150
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Acod1
Name: aconitate decarboxylase 1
Synonyms: Irg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16365
Homologene: 35405
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 628444
Homologene: 129683
4931417E11Rik
Name: RIKEN cDNA 4931417E11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 66740
Homologene: 75225
Pdzrn3
Name: PDZ domain containing RING finger 3
Synonyms: 1110020C07Rik, LNX3, Semcap3, semaphorin cytoplasmic domain-associated protein 3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 55983
Homologene: 10328
Mep1a
Name: meprin 1 alpha
Synonyms: Mep-1a, Mep-1, Mep1, meprin A alpha-subunit, meprin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545477
Homologene: 129594
Agbl2
Name: ATP/GTP binding protein-like 2
Synonyms: Ccp2, Ccp2, A430081C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 271813
Homologene: 11715
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Gm20547
Name: predicted gene 20547
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Tnfrsf11a
Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Synonyms: Rank, TRANCE-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21934
Homologene: 2848
Phkg2
Name: phosphorylase kinase, gamma 2 (testis)
Synonyms: 1500017I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68961
HGNC: HGNC:8931
Homologene: 47915
Vsig1
Name: V-set and immunoglobulin domain containing 1
Synonyms: 1700062D20Rik, 4930405J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 78789
Homologene: 12703
Ifit1bl1
Name: interferon induced protein with tetratricpeptide repeats 1B like 1
Synonyms: Gm14446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 667373
Homologene: 78213
Vmn1r209
Name: vomeronasal 1 receptor 209
Synonyms: Gm11315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 432736
Homologene: 110880
Fam90a1a
Name: family with sequence similarity 90, member A1A
Synonyms: C86695
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 97476
Homologene: 135718
Olfr38
Name: olfactory receptor 38
Synonyms: 18A, GA_x6K02T2P3E9-4797841-4796888, MOR257-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258988
HGNC: HGNC:8246
Homologene: 72050
4930447C04Rik
Name: RIKEN cDNA 4930447C04 gene
Synonyms: Six6os1, Six6as
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 75801
Homologene: 49922
Pkd2l1
Name: polycystic kidney disease 2-like 1
Synonyms: PCL, Pkdl, TRPP3, polycystin-L, PKD2L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 329064
HGNC: HGNC:9011
Homologene: 22946
Frmd3
Name: FERM domain containing 3
Synonyms: 4.1O, 9430066I12Rik, EPB41L4O, P410
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242506
Homologene: 16012
Adh6a
Name: alcohol dehydrogenase 6A (class V)
Synonyms: 1810009C16Rik, Adh5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69117
Homologene: 66291
Tox2
Name: TOX high mobility group box family member 2
Synonyms: LOC269389, RxHMG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269389
Homologene: 13155
Gm8214
Name: predicted gene 8214
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Gpr20
Name: G protein-coupled receptor 20
Synonyms: A430106B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239530
HGNC: HGNC:4475
Homologene: 3870
Ptger3
Name: prostaglandin E receptor 3 (subtype EP3)
Synonyms: Pgerep3, EP3, Ptgerep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19218
HGNC: HGNC:9595
Homologene: 105703
Slc35a5
Name: solute carrier family 35, member A5
Synonyms: D16Ertd450e, D730043G07Rik, 1010001J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74102
Homologene: 9930
Rdh16
Name: retinol dehydrogenase 16
Synonyms: Rdh6, cis-retinol/androgen dehydrogenase 1, CRAD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19683
Homologene: 129514
Igkv8-21
Name: immunoglobulin kappa variable 8-21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 620400
Ighv1-82
Name: immunoglobulin heavy variable 1-82
Synonyms: Gm16747
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100775175
Ighv2-9
Name: immunoglobulin heavy variable 2-9
Synonyms: Gm16700
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 640046
Maff
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17133
VEGA: 15
HGNC: HGNC:6780
Homologene: 7825
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 105,821,533 bp
  • T to C, chromosome 1 at 153,166,169 bp
  • T to C, chromosome 1 at 183,681,897 bp
  • T to A, chromosome 2 at 90,793,961 bp
  • T to A, chromosome 2 at 120,048,757 bp
  • T to C, chromosome 2 at 153,982,988 bp
  • T to C, chromosome 2 at 163,320,647 bp
  • A to T, chromosome 2 at 180,585,314 bp
  • T to C, chromosome 3 at 5,413,067 bp
  • A to T, chromosome 3 at 80,706,897 bp
  • A to G, chromosome 3 at 102,145,459 bp
  • A to T, chromosome 3 at 108,355,541 bp
  • A to T, chromosome 3 at 122,959,120 bp
  • A to T, chromosome 3 at 138,324,947 bp
  • T to C, chromosome 3 at 157,567,294 bp
  • T to C, chromosome 4 at 74,187,872 bp
  • T to A, chromosome 4 at 116,154,890 bp
  • A to G, chromosome 5 at 89,038,561 bp
  • G to T, chromosome 6 at 42,762,418 bp
  • G to A, chromosome 6 at 54,290,403 bp
  • A to T, chromosome 6 at 70,315,157 bp
  • A to G, chromosome 6 at 73,469,269 bp
  • G to T, chromosome 6 at 101,152,009 bp
  • A to G, chromosome 6 at 108,481,223 bp
  • A to G, chromosome 7 at 42,012,438 bp
  • T to C, chromosome 7 at 45,148,788 bp
  • G to T, chromosome 7 at 83,633,281 bp
  • A to G, chromosome 7 at 100,882,485 bp
  • C to T, chromosome 7 at 103,220,422 bp
  • C to T, chromosome 7 at 127,577,620 bp
  • C to A, chromosome 8 at 21,963,846 bp
  • T to C, chromosome 9 at 57,701,756 bp
  • T to C, chromosome 9 at 59,821,649 bp
  • C to T, chromosome 9 at 88,957,453 bp
  • A to T, chromosome 10 at 127,801,513 bp
  • G to A, chromosome 10 at 128,572,770 bp
  • C to A, chromosome 11 at 61,485,509 bp
  • T to C, chromosome 11 at 87,610,935 bp
  • T to C, chromosome 11 at 98,682,926 bp
  • T to C, chromosome 12 at 72,902,485 bp
  • G to T, chromosome 12 at 113,879,219 bp
  • T to C, chromosome 12 at 115,952,660 bp
  • A to T, chromosome 13 at 22,805,965 bp
  • G to A, chromosome 13 at 24,984,816 bp
  • G to A, chromosome 13 at 63,298,751 bp
  • C to T, chromosome 14 at 103,055,345 bp
  • A to G, chromosome 15 at 6,491,463 bp
  • T to C, chromosome 15 at 73,695,736 bp
  • A to G, chromosome 15 at 79,357,698 bp
  • A to G, chromosome 15 at 86,235,685 bp
  • T to A, chromosome 16 at 10,644,883 bp
  • A to T, chromosome 16 at 45,144,292 bp
  • T to A, chromosome 17 at 34,859,068 bp
  • T to C, chromosome 17 at 43,452,440 bp
  • C to T, chromosome 17 at 43,486,241 bp
  • T to C, chromosome 18 at 12,504,397 bp
  • T to C, chromosome 18 at 20,531,559 bp
  • T to C, chromosome 18 at 32,003,487 bp
  • T to A, chromosome 18 at 42,301,775 bp
  • T to G, chromosome 19 at 17,560,750 bp
  • T to C, chromosome 19 at 34,594,610 bp
  • C to A, chromosome 19 at 44,154,134 bp
  • C to T, chromosome 19 at 61,175,926 bp
  • G to T, chromosome X at 140,926,386 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4616 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041827-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.