Strain Name:
C57BL/6J-MtgxR4628Btlr/Mmmh
Stock Number:
041893-MU
Citation ID:
RRID:MMRRC_041893-MU
Other Names:
R4628 (G1), C57BL/6J-MtgxR4628Btlr
Major Collection:

Gene Information

Slc6a12
Name: solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Synonyms: Gabt2, BGT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14411
Homologene: 128225
Pias3
Name: protein inhibitor of activated STAT 3
Synonyms: Pias3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229615
Homologene: 4447
Kera
Name: keratocan
Synonyms: SLRR2B, CNA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16545
VEGA: 10
HGNC: HGNC:6309
Homologene: 5106
Defb3
Name: defensin beta 3
Synonyms: mBD-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 27358
Bcap29
Name: B cell receptor associated protein 29
Synonyms: Bap29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 12033
VEGA: 12
Homologene: 22411
Nup188
Name: nucleoporin 188
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227699
Homologene: 45683
Pdia3
Name: protein disulfide isomerase associated 3
Synonyms: ERp61, ERp60, ERp57, PDI-Q2, Plca, Erp, Grp58, PDI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14827
HGNC: HGNC:4606
Homologene: 68454
Lcmt1
Name: leucine carboxyl methyltransferase 1
Synonyms: Lcmt, LCMT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 30949
Homologene: 41123
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, RA-GEF-2, Pdzgef2, C030018K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192786
Homologene: 22968
Ankrd12
Name: ankyrin repeat domain 12
Synonyms: ANCO-2, GAC-1, 2900001A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106585
Homologene: 9059
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 360013
Homologene: 7977
Leo1
Name: Leo1, Paf1/RNA polymerase II complex component
Synonyms: LOC235497
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235497
VEGA: 9
Homologene: 133895
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Atxn3
Name: ataxin 3
Synonyms: Sca3, MJD1, 2210008M02Rik, ataxin-3, Mjd, Atx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110616
HGNC: HGNC:7106
Homologene: 3658
Kat14
Name: lysine acetyltransferase 14
Synonyms: 2510008M08Rik, D2Ertd473e, D2Wsu131e, ATAC2, Csrp2bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228714
Homologene: 10745
Stk39
Name: serine/threonine kinase 39
Synonyms: DCHT, SPAK, RF005, Rnl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 53416
Homologene: 22739
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: 5830451P18Rik, Duplin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67772
Homologene: 72405
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170935
Homologene: 15781
Pex5
Name: peroxisomal biogenesis factor 5
Synonyms: ESTM1, PTS1R, Pxr1, peroxisome biogenesis factor 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19305
HGNC: HGNC:9719
Homologene: 270
Ass1
Name: argininosuccinate synthetase 1
Synonyms: ASS, Ass-1, fold
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11898
HGNC: HGNC:758
Homologene: 6899
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72007
Homologene: 11244
Pemt
Name: phosphatidylethanolamine N-methyltransferase
Synonyms: Pempt, Pempt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18618
HGNC: HGNC:8830
Homologene: 6291
Ube2c
Name: ubiquitin-conjugating enzyme E2C
Synonyms: 1110015A16Rik, D2Ertd695e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68612
Homologene: 5096
Mcm6
Name: minichromosome maintenance complex component 6
Synonyms: Mcmd6, D1Wsu22e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17219
HGNC: HGNC:6949
Homologene: 4322
Hs1bp3
Name: HCLS1 binding protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 58240
VEGA: 12
Homologene: 10980
Rtraf
Name: RNA transcription, translation and transport factor
Synonyms: 2700060E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68045
VEGA: 14
Homologene: 9355
Spring1
Name: SREBF pathway regulator in golgi 1
Synonyms: 2410131K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76792
Homologene: 32599
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: D330020E01Rik, pcy, nephrocystin 3, 3632410F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Itga2
Name: integrin alpha 2
Synonyms: VLA-2 receptor, alpha 2 subunit, CD49B, DX5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212124
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Gm4847
Name: predicted gene 4847
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226604
Homologene: 101040
Lcn5
Name: lipocalin 5
Synonyms: MEP10, mE-RABP, Erabp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13863
Homologene: 7305
Cracr2b
Name: calcium release activated channel regulator 2B
Synonyms: 6330520A15Rik, Efcab4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 213573
Homologene: 45468
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 545030
Homologene: 83473
Ccser1
Name: coiled-coil serine rich 1
Synonyms: 6230405M12Rik, C130092O11Rik, Fam190a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232035
Homologene: 28086
Gm9457
Name: predicted gene 9457
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 669393
Homologene: 131643
Vwa3a
Name: von Willebrand factor A domain containing 3A
Synonyms: E030013G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233813
Homologene: 18607
Uroc1
Name: urocanase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243537
Homologene: 76629
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Duox1
Name: dual oxidase 1
Synonyms: LNOX1, 9930101G15Rik, NOXEF1, THOX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Maz
Name: MYC-associated zinc finger protein (purine-binding transcription factor)
Synonyms: Pur-1, PUR1, SAF-2, SAF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17188
HGNC: HGNC:6914
Homologene: 106451
Arid3a
Name: AT rich interactive domain 3A (BRIGHT-like)
Synonyms: Bright, Dri1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13496
HGNC: HGNC:3031
Homologene: 124247
Akr1c13
Name: aldo-keto reductase family 1, member C13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 27384
Homologene: 121208
Vmn1r124
Name: vomeronasal 1 receptor 124
Synonyms: Gm9500
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 670764
Homologene: 104166
Vmn2r85
Name: vomeronasal 2, receptor 85
Synonyms: EG623734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 623734
Homologene: 129606
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21974
Homologene: 134711
Olfr45
Name: olfactory receptor 45
Synonyms: IB6, MOR253-2, GA_x6K02T2PBJ9-42837030-42837962
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18344
Homologene: 79416
Postn
Name: periostin, osteoblast specific factor
Synonyms: OSF-2, Periostin, Osf2, peri, A630052E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50706
Homologene: 4730
Adamts18
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
Synonyms: E130314N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 208936
Homologene: 65241
Kctd21
Name: potassium channel tetramerisation domain containing 21
Synonyms: EG622320
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 622320
Homologene: 54754
Notch4
Name: notch 4
Synonyms: Int-3, Int3, N4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Olfr339
Name: olfactory receptor 339
Synonyms: GA_x6K02T2NLDC-33116096-33117025, MOR136-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258951
Homologene: 133615
Actn3
Name: actinin alpha 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11474
HGNC: HGNC:165
Homologene: 862
Engase
Name: endo-beta-N-acetylglucosaminidase
Synonyms: D230014K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217364
Homologene: 13666
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226438
Homologene: 130054
Fam98c
Name: family with sequence similarity 98, member C
Synonyms: B230110F21Rik, 1110006G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73833
Homologene: 45483
Lrrc8e
Name: leucine rich repeat containing 8 family, member E
Synonyms: C87354, 1810049O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72267
Homologene: 11817
Ovgp1
Name: oviductal glycoprotein 1
Synonyms: MOGP, muc9, mucin 9, oviductin, Chit5, OGP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12659
HGNC: HGNC:8524
Homologene: 74442
Vmn2r68
Name: vomeronasal 2, receptor 68
Synonyms: EG620697, Vmn2r68-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 620697
Homologene: 115466
Llgl1
Name: LLGL1 scribble cell polarity complex component
Synonyms: Lgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16897
HGNC: HGNC:6628
Homologene: 31220
Colq
Name: collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 102639719
HGNC: HGNC:2226
Alkbh2
Name: alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
Synonyms: Abh2, mABH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231642
Homologene: 18393
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Otud4
Name: OTU domain containing 4
Synonyms: 4930431L18Rik, D8Ertd69e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73945
Homologene: 35370
Krt1
Name: keratin 1
Synonyms: Krt2-1, Krt-2.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16678
VEGA: 15
HGNC: HGNC:6412
Homologene: 38146
Gm9772
Name: predicted gene 9772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100416807
VEGA: 17
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Prl7c1
Name: prolactin family 7, subfamily c, member 1
Synonyms: PLP-O, 1600017N11Rik, Prlpo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67505
Homologene: 137377
AF366264
Name: cDNA sequence AF366264
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 231201
Homologene: 130042
Maml3
Name: mastermind like transcriptional coactivator 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433586
Homologene: 41284
Gpr162
Name: G protein-coupled receptor 162
Synonyms: A-2, Grca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14788
Homologene: 8400
Tmtc2
Name: transmembrane and tetratricopeptide repeat containing 2
Synonyms: D330034A10Rik, 8430438D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 278279
Homologene: 25521
Hsd3b6
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
Synonyms: 3beta-HSD VI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15497
Homologene: 133013
Olfr61
Name: olfactory receptor 61
Synonyms: IH7, MOR253-1, GA_x6K02T2PBJ9-42783826-42784758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18362
Homologene: 79374
BC007180
Name: cDNA sequence BC007180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Srcin1
Name: SRC kinase signaling inhibitor 1
Synonyms: P140, p140Cap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56013
Homologene: 10324
Gm15645
Name: predicted gene 15645
Synonyms: EG626055
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 626055
Ptprv
Name: protein tyrosine phosphatase, receptor type, V
Synonyms: mOST-PTP, Esp, OST-PTP, OST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13924
Homologene: 7306
Vmn1r57
Name: vomeronasal 1 receptor 57
Synonyms: Gm7519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 665150
Homologene: 41799
Rmi1
Name: RecQ mediated genome instability 1
Synonyms: 4932432N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74386
VEGA: 13
Homologene: 41601
BC022960
Name: cDNA sequence BC022960
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Gm9804
Name: predicted gene 9804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Gm8894
Name: predicted gene 8894
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 667952
VEGA: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 128,351,548 bp
  • T to C, chromosome 1 at 135,124,131 bp
  • T to C, chromosome 1 at 135,959,730 bp
  • A to T, chromosome 1 at 166,630,395 bp
  • A to G, chromosome 2 at 25,658,063 bp
  • A to G, chromosome 2 at 30,329,346 bp
  • A to T, chromosome 2 at 31,480,988 bp
  • T to A, chromosome 2 at 36,421,857 bp
  • T to A, chromosome 2 at 52,308,350 bp
  • A to T, chromosome 2 at 68,263,201 bp
  • A to T, chromosome 2 at 121,414,139 bp
  • A to G, chromosome 2 at 122,346,252 bp
  • A to G, chromosome 2 at 144,404,220 bp
  • A to G, chromosome 2 at 164,772,173 bp
  • G to A, chromosome 3 at 5,403,476 bp
  • T to C, chromosome 3 at 27,556,128 bp
  • A to T, chromosome 3 at 51,796,470 bp
  • A to G, chromosome 3 at 54,372,157 bp
  • T to C, chromosome 3 at 96,699,820 bp
  • T to G, chromosome 3 at 98,806,579 bp
  • T to A, chromosome 3 at 105,980,323 bp
  • A to T, chromosome 3 at 154,763,687 bp
  • C to T, chromosome 5 at 114,124,226 bp
  • G to C, chromosome 5 at 118,259,414 bp
  • T to C, chromosome 5 at 143,382,875 bp
  • T to A, chromosome 6 at 61,311,646 bp
  • A to T, chromosome 6 at 90,355,328 bp
  • T to A, chromosome 6 at 121,351,992 bp
  • T to C, chromosome 6 at 124,403,120 bp
  • C to T, chromosome 6 at 124,861,442 bp
  • T to A, chromosome 7 at 5,220,973 bp
  • T to A, chromosome 7 at 21,260,377 bp
  • T to C, chromosome 7 at 29,155,268 bp
  • A to G, chromosome 7 at 85,234,465 bp
  • A to G, chromosome 7 at 97,347,575 bp
  • A to G, chromosome 7 at 105,764,499 bp
  • T to A, chromosome 7 at 120,793,375 bp
  • T to A, chromosome 7 at 123,410,812 bp
  • G to T, chromosome 7 at 127,025,347 bp
  • A to T, chromosome 7 at 139,680,927 bp
  • C to T, chromosome 7 at 140,638,384 bp
  • T to A, chromosome 7 at 140,691,378 bp
  • C to A, chromosome 7 at 141,464,739 bp
  • T to A, chromosome 8 at 4,233,981 bp
  • T to G, chromosome 8 at 4,813,013 bp
  • T to A, chromosome 8 at 13,836,625 bp
  • A to T, chromosome 8 at 19,295,140 bp
  • T to A, chromosome 8 at 79,639,968 bp
  • C to T, chromosome 8 at 113,773,168 bp
  • A to T, chromosome 9 at 75,445,697 bp
  • A to G, chromosome 9 at 104,003,058 bp
  • G to T, chromosome 9 at 108,113,235 bp
  • T to C, chromosome 10 at 79,931,158 bp
  • G to T, chromosome 10 at 80,015,188 bp
  • A to G, chromosome 10 at 97,609,631 bp
  • A to T, chromosome 10 at 105,303,650 bp
  • C to T, chromosome 10 at 130,425,366 bp
  • A to T, chromosome 11 at 54,619,912 bp
  • C to A, chromosome 11 at 59,983,572 bp
  • A to T, chromosome 11 at 60,709,985 bp
  • G to A, chromosome 11 at 77,824,136 bp
  • T to A, chromosome 11 at 97,548,926 bp
  • C to T, chromosome 11 at 118,484,905 bp
  • T to C, chromosome 12 at 8,336,357 bp
  • C to T, chromosome 12 at 31,626,807 bp
  • T to C, chromosome 12 at 49,401,757 bp
  • T to A, chromosome 12 at 101,923,078 bp
  • G to T, chromosome 13 at 4,197,870 bp
  • T to C, chromosome 13 at 27,778,082 bp
  • A to G, chromosome 13 at 58,409,136 bp
  • A to G, chromosome 13 at 95,763,329 bp
  • A to G, chromosome 13 at 114,877,693 bp
  • T to G, chromosome 14 at 16,409,189 bp
  • T to A, chromosome 14 at 19,817,087 bp
  • C to A, chromosome 14 at 31,544,022 bp
  • A to T, chromosome 14 at 33,102,558 bp
  • T to C, chromosome 14 at 52,206,915 bp
  • A to C, chromosome 14 at 55,420,309 bp
  • T to A, chromosome 15 at 55,449,833 bp
  • C to T, chromosome 15 at 101,846,187 bp
  • T to C, chromosome 17 at 22,007,207 bp
  • C to A, chromosome 17 at 34,570,185 bp
  • T to C, chromosome 17 at 65,985,994 bp
  • T to A, chromosome 18 at 25,120,129 bp
  • T to C, chromosome 19 at 4,861,303 bp
  • T to C, chromosome X at 169,369,278 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4628 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041893-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.