Strain Name:
C57BL/6J-MtgxR4656Btlr/Mmmh
Stock Number:
041916-MU
Citation ID:
RRID:MMRRC_041916-MU
Other Names:
R4656 (G1), C57BL/6J-MtgxR4656Btlr
Major Collection:

Gene Information

Col2a1
Name: collagen, type II, alpha 1
Synonyms: Del1, Col2a-1, Col2a, Col2, M100856, Rgsc856, Lpk, M100413, Rgsc413
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12824
HGNC: HGNC:2200
Homologene: 55607
Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 22427
Homologene: 6659
Spns1
Name: spinster homolog 1
Synonyms: 2210013K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73658
Homologene: 41530
Mif4gd
Name: MIF4G domain containing
Synonyms: 1110014L05Rik, 2310075G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69674
Homologene: 41389
Pdzd2
Name: PDZ domain containing 2
Synonyms: 4930537L06Rik, LOC223364, A930022H17Rik, Pdzk3, Gm21706
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68070
Homologene: 23393
Egln2
Name: egl-9 family hypoxia-inducible factor 2
Synonyms: SM-20, Ier4, 0610011A13Rik, Phd1, Hif-p4h-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 112406
Homologene: 14204
Shroom3
Name: shroom family member 3
Synonyms: D5Ertd287e, Shrm, Shrm3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 27428
Homologene: 9263
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22222
Homologene: 7582
Gigyf1
Name: GRB10 interacting GYF protein 1
Synonyms: Perq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57330
HGNC: HGNC:9126
Homologene: 57145
Ago3
Name: argonaute RISC catalytic subunit 3
Synonyms: argonaute 3, eIF2C3, C130014L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214150
Homologene: 49799
Smg1
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase
Synonyms: C130002K18Rik, 5430435M13Rik, 2610207I05Rik, SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233789
Homologene: 56697
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19386
VEGA: 10
Homologene: 87808
Gabpb2
Name: GA repeat binding protein, beta 2
Synonyms: 9430006E19Rik, Gabpb2-1, A430024B14Rik, 1810015F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213054
Homologene: 34921
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Polr3f
Name: polymerase (RNA) III (DNA directed) polypeptide F
Synonyms: 3110032A07Rik, 2810411G20Rik, RPC39, RPC6, 3010019O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70408
Homologene: 4722
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: ZWS1, 5430414H02Rik, E330005K07Rik, peroxisome biogenesis factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Armc10
Name: armadillo repeat containing 10
Synonyms: 2810037C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67211
Homologene: 12097
Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Synonyms: cytochrome P450 subfamily I, polypeptide 1, P450-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13076
VEGA: 9
HGNC: HGNC:2595
Homologene: 68062
Ace2
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Synonyms: 2010305L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 70008
Homologene: 41448
Megf9
Name: multiple EGF-like-domains 9
Synonyms: 4933405H16Rik, Egfl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230316
HGNC: HGNC:3234
Homologene: 18209
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22767
Homologene: 56456
Tars
Name: threonyl-tRNA synthetase
Synonyms: ThrRS, D15Wsu59e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110960
VEGA: 15
Homologene: 11852
Vezf1
Name: vascular endothelial zinc finger 1
Synonyms: db1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22344
Homologene: 5175
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Brd3
Name: bromodomain containing 3
Synonyms: RINGL3, ORFX, 2410084F24Rik, Fsrg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67382
HGNC: HGNC:1104
Homologene: 81801
Rbm14
Name: RNA binding motif protein 14
Synonyms: p16, 1300007E16Rik, PSP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56275
Homologene: 4614
Usp6nl
Name: USP6 N-terminal like
Synonyms: TRE2NL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98910
Homologene: 6879
Gpr107
Name: G protein-coupled receptor 107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277463
Homologene: 81077
Gnl2
Name: guanine nucleotide binding protein-like 2 (nucleolar)
Synonyms: Ngp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230737
Homologene: 6858
Eda2r
Name: ectodysplasin A2 receptor
Synonyms: 9430060M22Rik, Xedar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245527
Homologene: 11033
Nhlrc3
Name: NHL repeat containing 3
Synonyms: 8030451K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 212114
Homologene: 35239
Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Synonyms: H+K+-transporting alpha 1, H+/K+-ATPase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11944
HGNC: HGNC:819
Homologene: 68081
Mcoln1
Name: mucolipin 1
Synonyms: 2210015I05Rik, mucolipidin, TRPML1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94178
Homologene: 10744
Grpr
Name: gastrin releasing peptide receptor
Synonyms: bombesin receptor, GRP-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 14829
HGNC: HGNC:4609
Homologene: 21098
Pramel32
Name: PRAME like 32
Synonyms: C87499
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381590
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Casp1
Name: caspase 1
Synonyms: ICE, Caspase-1, interleukin 1 beta-converting enzyme, Il1bc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12362
VEGA: 9
HGNC: HGNC:1499
Homologene: 133272
4931406B18Rik
Name: RIKEN cDNA 4931406B18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74054
Homologene: 105741
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Taf5l
Name: TATA-box binding protein associated factor 5 like
Synonyms: 1110005N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102162
Homologene: 8676
Slc22a29
Name: solute carrier family 22. member 29
Synonyms: D630002G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 236293
Homologene: 77136
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Oas3
Name: 2'-5' oligoadenylate synthetase 3
Synonyms: 2'-5' oligoadenylate synthetase-like 10, Oasl10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246727
HGNC: HGNC:8088
Homologene: 4510
Itgal
Name: integrin alpha L
Synonyms: LFA-1, Cd11a, Ly-21, Ly-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Tdrd12
Name: tudor domain containing 12
Synonyms: 2410070K17Rik, G1-476-14, ecat8, 2410004F06Rik, EG434165, repro23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71981
Homologene: 87053
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215772
Homologene: 100289
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Shc2
Name: SHC (Src homology 2 domain containing) transforming protein 2
Synonyms: ShcB, Sli
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216148
Homologene: 19127
Txlnb
Name: taxilin beta
Synonyms: Mdp77, 2310001N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 378431
Homologene: 44534
Krt13
Name: keratin 13
Synonyms: Krt-1.13, K13, Krt1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16663
HGNC: HGNC:6415
Homologene: 40740
Vmn2r66
Name: vomeronasal 2, receptor 66
Synonyms: F830104D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233437
Homologene: 115466
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: 1110036I10Rik, VRL3, Nh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246788
Homologene: 17040
Disp2
Name: dispatched RND tramsporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214240
Homologene: 24916
Olfr390
Name: olfactory receptor 390
Synonyms: GA_x6K02T2P1NL-3938806-3939741, MOR135-26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258344
Homologene: 115483
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218165
VEGA: 13
Homologene: 125376
Ces2h
Name: carboxylesterase 2H
Synonyms: Gm5744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 436059
HGNC: HGNC:1864
Homologene: 128645
Gsdma
Name: gasdermin A
Synonyms: H312E, Gsdm, Gsdm1, Gsdma1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57911
Homologene: 10962
Cfap410
Name: cilia and flagella associated protein 410
Synonyms: D10Jhu13e, 1810043G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67884
HGNC: HGNC:1260
Homologene: 3619
Dcaf7
Name: DDB1 and CUL4 associated factor 7
Synonyms: 2610037L01Rik, 1700012F10Rik, Wdr68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71833
Homologene: 55930
BC051076
Name: cDNA sequence BC051076
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243090
Slco6d1
Name: solute carrier organic anion transporter family, member 6d1
Synonyms: 4921511I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70866
Homologene: 86643
Plch1
Name: phospholipase C, eta 1
Synonyms: PLCeta1, Plcl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 269437
Homologene: 88833
Slco4c1
Name: solute carrier organic anion transporter family, member 4C1
Synonyms: SLC21A20, PRO2176, OATP4C1, OATP-M1, OATP-H, C330017E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227394
Homologene: 62654
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74682
Homologene: 10814
Slc5a9
Name: solute carrier family 5 (sodium/glucose cotransporter), member 9
Synonyms: SGLT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230612
Homologene: 17081
Ces1b
Name: carboxylesterase 1B
Synonyms: Gm5158
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382044
HGNC: HGNC:1863
Homologene: 117484
Marchf1
Name: membrane associated ring-CH-type finger 1
Synonyms: 2900024D24Rik, March1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72925
Homologene: 113749
Skint1
Name: selection and upkeep of intraepithelial T cells 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 639781
Homologene: 87538
Nr1h4
Name: nuclear receptor subfamily 1, group H, member 4
Synonyms: RIP14, FXR, HRR1, Rxrip14, Fxr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20186
HGNC: HGNC:7967
Homologene: 3760
Nipal2
Name: NIPA-like domain containing 2
Synonyms: 9330161F08Rik, Npal2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223473
VEGA: 15
Homologene: 41586
Irx2
Name: Iroquois homeobox 2
Synonyms: IRX6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16372
Homologene: 56490
Rmi2
Name: RecQ mediated genome instability 2
Synonyms: LOC381034, A630055G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223970
Homologene: 17543
Olfr607
Name: olfactory receptor 607
Synonyms: GA_x6K02T2PBJ9-6182881-6181898, MOR33-3P, EG546989, Gm15121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546989
Homologene: 78211
Ifi204
Name: interferon activated gene 204
Synonyms: p204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15951
HGNC: HGNC:5395
Homologene: 115929
Serpina3k
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3K
Synonyms: contrapsin, Spi-2, D12Rp54, RP54, Spi2, MMSpi2, MMCM2, alpha-1 antiproteinase, 1300001I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20714
HGNC: HGNC:16
Homologene: 111129
Ceacam9
Name: carcinoembryonic antigen-related cell adhesion molecule 9
Synonyms: mmCGM8, Cea-5, Cea5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26368
Homologene: 74987
Mroh9
Name: maestro heat-like repeat family member 9
Synonyms: 4921528O07Rik, Armc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78258
Homologene: 123521
Gm14149
Name: predicted gene 14149
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100038513
Gm12715
Name: predicted gene 12715
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100039940
Gm13070
Name: predicted gene 13070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 105247219
Olfr908
Name: olfactory receptor 908
Synonyms: GA_x6K02T2PVTD-32216179-32217111, MOR165-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258872
VEGA: 9
Homologene: 74149
Uqcrb
Name: ubiquinol-cytochrome c reductase binding protein
Synonyms: QP-C, 2210415M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67530
Homologene: 38164
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 96,841,245 bp
  • T to C, chromosome 1 at 98,423,203 bp
  • A to T, chromosome 1 at 163,066,024 bp
  • C to A, chromosome 1 at 173,760,361 bp
  • A to G, chromosome 2 at 6,441,162 bp
  • A to G, chromosome 2 at 27,454,394 bp
  • C to T, chromosome 2 at 31,214,249 bp
  • T to C, chromosome 2 at 118,790,563 bp
  • A to G, chromosome 2 at 120,926,013 bp
  • A to T, chromosome 2 at 144,536,336 bp
  • A to T, chromosome 2 at 151,230,764 bp
  • A to G, chromosome 3 at 53,463,080 bp
  • G to T, chromosome 3 at 63,704,177 bp
  • A to G, chromosome 3 at 95,188,941 bp
  • T to C, chromosome 4 at 70,448,767 bp
  • T to C, chromosome 4 at 88,629,965 bp
  • A to C, chromosome 4 at 103,563,664 bp
  • C to A, chromosome 4 at 111,891,744 bp
  • A to G, chromosome 4 at 112,021,477 bp
  • C to T, chromosome 4 at 125,040,997 bp
  • G to T, chromosome 4 at 126,363,752 bp
  • A to G, chromosome 4 at 149,906,410 bp
  • G to A, chromosome 5 at 3,604,880 bp
  • A to G, chromosome 5 at 21,661,550 bp
  • G to A, chromosome 5 at 87,964,675 bp
  • C to T, chromosome 5 at 92,964,391 bp
  • T to G, chromosome 5 at 120,777,471 bp
  • C to A, chromosome 5 at 137,525,215 bp
  • T to G, chromosome 6 at 48,454,076 bp
  • C to T, chromosome 7 at 16,723,649 bp
  • A to G, chromosome 7 at 27,159,193 bp
  • T to G, chromosome 7 at 30,719,948 bp
  • T to C, chromosome 7 at 35,485,254 bp
  • T to A, chromosome 7 at 43,501,141 bp
  • A to G, chromosome 7 at 85,011,996 bp
  • C to T, chromosome 7 at 103,460,488 bp
  • A to T, chromosome 7 at 118,212,951 bp
  • G to T, chromosome 7 at 126,374,302 bp
  • T to A, chromosome 7 at 127,322,553 bp
  • T to C, chromosome 8 at 3,511,768 bp
  • A to T, chromosome 8 at 33,335,991 bp
  • A to G, chromosome 8 at 48,293,726 bp
  • C to T, chromosome 8 at 54,681,399 bp
  • T to A, chromosome 8 at 66,386,419 bp
  • C to G, chromosome 8 at 93,057,414 bp
  • A to T, chromosome 8 at 105,014,639 bp
  • T to C, chromosome 8 at 123,998,105 bp
  • C to T, chromosome 9 at 5,304,324 bp
  • A to T, chromosome 9 at 38,516,556 bp
  • T to C, chromosome 9 at 57,702,610 bp
  • A to G, chromosome 9 at 66,394,711 bp
  • A to C, chromosome 10 at 10,405,306 bp
  • A to T, chromosome 10 at 17,815,276 bp
  • A to G, chromosome 10 at 58,453,422 bp
  • G to A, chromosome 10 at 77,981,616 bp
  • A to T, chromosome 10 at 79,621,169 bp
  • A to G, chromosome 10 at 89,498,253 bp
  • T to A, chromosome 11 at 73,295,414 bp
  • A to T, chromosome 11 at 73,787,511 bp
  • A to G, chromosome 11 at 88,074,667 bp
  • T to C, chromosome 11 at 98,673,081 bp
  • C to A, chromosome 11 at 100,119,363 bp
  • T to C, chromosome 11 at 106,053,798 bp
  • G to T, chromosome 11 at 115,608,337 bp
  • T to A, chromosome 12 at 9,016,619 bp
  • T to C, chromosome 12 at 76,031,373 bp
  • C to A, chromosome 12 at 104,345,273 bp
  • G to A, chromosome 13 at 40,015,388 bp
  • T to C, chromosome 13 at 66,901,539 bp
  • T to C, chromosome 13 at 72,631,298 bp
  • A to T, chromosome 15 at 11,394,264 bp
  • A to G, chromosome 15 at 12,385,711 bp
  • A to T, chromosome 15 at 34,577,568 bp
  • C to T, chromosome 15 at 97,976,176 bp
  • A to G, chromosome 16 at 10,835,322 bp
  • T to C, chromosome 19 at 4,811,435 bp
  • C to A, chromosome 19 at 8,218,300 bp
  • G to A, chromosome 19 at 9,004,855 bp
  • T to A, chromosome X at 97,341,633 bp
  • T to A, chromosome X at 163,514,996 bp
  • T to C, chromosome X at 164,153,114 bp
  • T to G, chromosome Y at 729,626 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4656 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041916-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.