Strain Name:
C57BL/6J-MtgxR4710Btlr/Mmmh
Stock Number:
042019-MU
Citation ID:
RRID:MMRRC_042019-MU
Other Names:
R4710 (G1), C57BL/6J-MtgxR4710Btlr
Major Collection:

Strain Information

Lamb1
Name: laminin B1
Synonyms: Lamb-1, C81607, C80098, D130003D08Rik, Lamb1-1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16777
HGNC: HGNC:6486
Homologene: 1722
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: RNCAM, R4B12 antigen, Ncam-2, Ocam
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Lias
Name: lipoic acid synthetase
Synonyms: MGC7254, mLip1, 4933425M12Rik, 2900022L22Rik, 7a5ex
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 79464
Homologene: 4997
Rnf220
Name: ring finger protein 220
Synonyms: 5730503K05Rik, 4931406I20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66743
Homologene: 10036
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: 5830434P21Rik, Bat2l
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227723
Homologene: 106649
Dclre1c
Name: DNA cross-link repair 1C
Synonyms: 9930121L06Rik, Artemis, Art
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227525
Homologene: 32547
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: LOC380993, Zfp406, Zfat1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 380993
Homologene: 16829
Snrnp200
Name: small nuclear ribonucleoprotein 200 (U5)
Synonyms: U5-200KD, HELIC2, A330064G03Rik, Ascc3l1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320632
Homologene: 5859
Coro7
Name: coronin 7
Synonyms: 0610011B16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78885
Homologene: 11573
Mphosph6
Name: M phase phosphoprotein 6
Synonyms: C86426, 1110001M01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68533
HGNC: HGNC:7214
Homologene: 38100
Kcnk1
Name: potassium channel, subfamily K, member 1
Synonyms: TWIK-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16525
HGNC: HGNC:6272
Homologene: 1691
Nbr1
Name: NBR1, autophagy cargo receptor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17966
HGNC: HGNC:6746
Homologene: 7438
Zfp719
Name: zinc finger protein 719
Synonyms: C630016O21Rik, mszf6, 9430094P17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210105
Cntn2
Name: contactin 2
Synonyms: Tax, TAG-1, axonin, D130012K04Rik, TAG1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Zbtb20
Name: zinc finger and BTB domain containing 20
Synonyms: 1300017A20Rik, D16Wsu73e, Zfp288, A930017C21Rik, 7330412A13Rik, HOF
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56490
Homologene: 9226
Fabp3
Name: fatty acid binding protein 3, muscle and heart
Synonyms: H-FABP, Fabph-4, Fabph-1, Fabph4, Fabph1, Mdgi, Fabp3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14077
HGNC: HGNC:3557
Homologene: 68379
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Ndel1
Name: nudE neurodevelopment protein 1 like 1
Synonyms: 2600006O07Rik, mNudel
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 83431
Homologene: 32567
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: VIa, sema, Sema6A-1, Semaq, A730020P05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20358
Homologene: 32426
Ap1b1
Name: adaptor protein complex AP-1, beta 1 subunit
Synonyms: beta-prime adaptin, Adtb1, b2b1660Clo
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11764
HGNC: HGNC:554
Homologene: 21972
Mta2
Name: metastasis-associated gene family, member 2
Synonyms: mmta2, Mta1l1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 23942
HGNC: HGNC:7411
Homologene: 3480
Maea
Name: macrophage erythroblast attacher
Synonyms: 1110030D19Rik, Gid9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59003
Homologene: 4298
Rae1
Name: ribonucleic acid export 1
Synonyms: MNRP41, MNRP, 41, D2Ertd342e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66679
HGNC: HGNC:9828
Homologene: 2676
Gnl2
Name: guanine nucleotide binding protein nucleolar 2
Synonyms: Ngp-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230737
Homologene: 6858
Sost
Name: sclerostin
Synonyms: 5430411E23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74499
Homologene: 11542
Cd209b
Name: CD209b antigen
Synonyms: SIGNR1, mSIGNR1, 1810030I22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69165
Homologene: 84858
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Inhba
Name: inhibin beta-A
Synonyms: activin beta-A
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16323
VEGA: 13
HGNC: HGNC:6066
Homologene: 1653
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Or6d13
Name: olfactory receptor family 6 subfamily D member 13
Synonyms: GA_x54KRFPKN04-58174409-58175392, MOR119-3, Olfr213
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258020
Homologene: 74186
Rnf112
Name: ring finger protein 112
Synonyms: bfp, Zfp179, neurolastin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22671
Homologene: 5176
Commd3
Name: COMM domain containing 3
Synonyms: D2Ertd542e, Bup
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12238
Homologene: 15693
Kansl1l
Name: KAT8 regulatory NSL complex subunit 1-like
Synonyms: C430010P07Rik, 1110028C15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68691
Homologene: 27376
Slc25a48
Name: solute carrier family 25, member 48
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 328258
Homologene: 27065
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637908
Homologene: 104040
Adamts18
Name: ADAM metallopeptidase with thrombospondin type 1 motif 18
Synonyms: E130314N14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 208936
Homologene: 65241
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71872
Homologene: 70273
Or10ag53
Name: olfactory receptor family 10 subfamily AG member 53
Synonyms: GA_x6K02T2Q125-48736906-48737886, MOR273-4P, MOR273-4P, MOR264-20, Olfr1530-ps1, Olfr1115
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258294
Homologene: 27114
H2-Q2
Name: histocompatibility 2, Q region locus 2
Synonyms: H-2Q2, Gm11132
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15013
Homologene: 128352
Bpifb6
Name: BPI fold containing family B, member 6
Synonyms: LOC228796, Bpil3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228796
Homologene: 18375
Tas2r104
Name: taste receptor, type 2, member 104
Synonyms: Tas2r4, T2R04, mGR04, mt2r45
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387340
Homologene: 130072
Or5h19
Name: olfactory receptor family 5 subfamily H member 19
Synonyms: GA_x54KRFPKG5P-55265713-55264787, MOR183-8, Olfr187
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258319
Homologene: 133069
F11
Name: coagulation factor XI
Synonyms: plasma thromboplastin antecedent, FXI, Cf11, 1600027G01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Smtn
Name: smoothelin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 29856
Homologene: 8482
Hmgxb3
Name: HMG box domain containing 3
Synonyms: 2510002C16Rik, A630042L21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 106894
VEGA: 18
Homologene: 44229
Vmn2r4
Name: vomeronasal 2, receptor 4
Synonyms: EG637053
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 637053
Homologene: 129754
Traf3ip2
Name: TRAF3 interacting protein 2
Synonyms: Act1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103213
HGNC: HGNC:1343
Homologene: 15885
Prkn
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkin, Park2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50873
HGNC: HGNC:8607
Homologene: 3355
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: YSPL3, SVCT2, Slc23a1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54338
Homologene: 68440
Or9a2
Name: olfactory receptor family 9 subfamily A member 2
Synonyms: GA_x6K02T2P3E9-5780974-5781915, MOR120-1, Olfr459
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258569
Homologene: 83448
Fkbp7
Name: FK506 binding protein 7
Synonyms: FKBP23
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14231
HGNC: HGNC:3723
Homologene: 22568
Gimd1
Name: GIMAP family P-loop NTPase domain containing 1
Synonyms: Gm5549
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 433653
Homologene: 47516
Kcnk9
Name: potassium channel, subfamily K, member 9
Synonyms: Task3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223604
VEGA: 15
HGNC: HGNC:6283
Homologene: 56758
Bag4
Name: BCL2-associated athanogene 4
Synonyms: 2410112I15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67384
HGNC: HGNC:940
Homologene: 31270
Erg
Name: ETS transcription factor
Synonyms: D030036I24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13876
HGNC: HGNC:3446
Homologene: 15848
Dpp4
Name: dipeptidylpeptidase 4
Synonyms: THAM, Dpp-4, Cd26
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13482
HGNC: HGNC:3009
Homologene: 3279
Or2t46
Name: olfactory receptor family 2 subfamily T member 46
Synonyms: GA_x6K02T2NKPP-844642-843680, MOR275-5, MOR275-11_p, Olfr325
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258261
Homologene: 133015
Or4c3d
Name: olfactory receptor family 4 subfamily C member 3D
Synonyms: A16, GA_x6K02T2Q125-51484508-51483600, MOR235-1, Olfr140
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57272
Homologene: 41379
Ifi213
Name: interferon activated gene 213
Synonyms: E030037K03Rik, Pydc4, Pyr-A
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 623121
HGNC: HGNC:5395
Homologene: 115929
Mdfi
Name: MyoD family inhibitor
Synonyms: I-mf, I-mfa
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17240
HGNC: HGNC:6967
Homologene: 21150
Sgms1
Name: sphingomyelin synthase 1
Synonyms: SMS1, 9530058O11Rik, SMS1gamma, SMS1beta, SMS1alpha2, SMS1alpha1, Tmem23
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 208449
Homologene: 27040
Dnaaf3
Name: dynein, axonemal assembly factor 3
Synonyms: 6030429G01Rik, b2b1739Clo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 436022
Homologene: 16205
Ctf1
Name: cardiotrophin 1
Synonyms: CT-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13019
HGNC: HGNC:2499
Homologene: 1016
Larp7-ps
Name: La ribonucleoprotein 7, transcriptional regulator, pseudogene
Synonyms: Gm12666
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68280
Sox18
Name: SRY (sex determining region Y)-box 18
Synonyms: Sry-related HMG-box gene 18, Ragl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20672
Homologene: 7546
Gm5526
Name: predicted pseudogene 5526
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 433297
Stk-ps1
Name: serine/threonine kinase, pseudogene 1
Synonyms: LOC240091, LOC333716, Gm318
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 545204
Homologene: 141143
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 45,857,419 bp
  • A to T, chromosome 1 at 58,255,638 bp
  • G to A, chromosome 1 at 66,801,496 bp
  • T to A, chromosome 1 at 132,528,225 bp
  • G to A, chromosome 1 at 173,567,172 bp
  • T to C, chromosome 2 at 3,440,861 bp
  • A to G, chromosome 2 at 18,674,282 bp
  • T to A, chromosome 2 at 32,193,857 bp
  • T to C, chromosome 2 at 52,260,598 bp
  • A to G, chromosome 2 at 62,360,315 bp
  • G to A, chromosome 2 at 76,663,254 bp
  • A to G, chromosome 2 at 76,752,084 bp
  • T to A, chromosome 2 at 87,252,040 bp
  • T to C, chromosome 2 at 90,052,150 bp
  • G to A, chromosome 2 at 112,766,301 bp
  • T to C, chromosome 2 at 127,226,133 bp
  • T to C, chromosome 2 at 132,056,709 bp
  • T to A, chromosome 2 at 153,908,516 bp
  • G to T, chromosome 2 at 173,015,392 bp
  • A to G, chromosome 2 at 181,670,895 bp
  • A to G, chromosome 3 at 64,409,780 bp
  • T to C, chromosome 3 at 132,634,848 bp
  • T to C, chromosome 4 at 92,190,975 bp
  • C to T, chromosome 4 at 117,289,214 bp
  • T to A, chromosome 4 at 125,053,459 bp
  • C to T, chromosome 4 at 130,312,387 bp
  • C to T, chromosome 5 at 33,368,690 bp
  • A to G, chromosome 5 at 65,397,727 bp
  • G to T, chromosome 6 at 41,771,508 bp
  • C to A, chromosome 6 at 84,097,715 bp
  • T to C, chromosome 6 at 116,540,650 bp
  • A to T, chromosome 6 at 121,641,303 bp
  • T to A, chromosome 6 at 131,685,444 bp
  • A to T, chromosome 7 at 4,526,494 bp
  • T to A, chromosome 7 at 12,601,202 bp
  • A to T, chromosome 7 at 28,094,961 bp
  • C to T, chromosome 7 at 43,590,232 bp
  • C to A, chromosome 7 at 127,717,080 bp
  • T to C, chromosome 8 at 3,924,215 bp
  • C to A, chromosome 8 at 11,409,462 bp
  • C to T, chromosome 8 at 25,769,488 bp
  • T to C, chromosome 8 at 45,250,146 bp
  • A to G, chromosome 8 at 113,706,926 bp
  • T to A, chromosome 8 at 117,801,902 bp
  • T to A, chromosome 8 at 126,029,528 bp
  • C to T, chromosome 10 at 39,639,260 bp
  • G to A, chromosome 11 at 3,524,663 bp
  • A to G, chromosome 11 at 5,031,664 bp
  • A to T, chromosome 11 at 58,581,722 bp
  • T to C, chromosome 11 at 61,449,831 bp
  • A to G, chromosome 11 at 68,845,337 bp
  • A to G, chromosome 11 at 69,478,077 bp
  • T to A, chromosome 11 at 84,392,337 bp
  • C to T, chromosome 11 at 101,575,275 bp
  • G to A, chromosome 11 at 101,966,844 bp
  • A to G, chromosome 12 at 31,282,583 bp
  • T to C, chromosome 13 at 16,026,483 bp
  • C to T, chromosome 13 at 56,463,566 bp
  • A to T, chromosome 15 at 68,180,282 bp
  • A to G, chromosome 15 at 72,512,975 bp
  • G to A, chromosome 15 at 91,699,927 bp
  • T to G, chromosome 16 at 4,634,933 bp
  • G to T, chromosome 16 at 43,610,676 bp
  • T to A, chromosome 16 at 59,036,275 bp
  • T to A, chromosome 16 at 81,465,706 bp
  • T to C, chromosome 16 at 95,390,034 bp
  • A to C, chromosome 17 at 11,854,833 bp
  • A to G, chromosome 17 at 35,343,302 bp
  • A to G, chromosome 17 at 36,397,670 bp
  • T to A, chromosome 17 at 47,824,586 bp
  • T to C, chromosome 18 at 47,270,683 bp
  • G to A, chromosome 18 at 61,137,475 bp
  • T to A, chromosome 19 at 8,949,153 bp
  • C to T, chromosome 19 at 32,160,137 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4710 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042019-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.