Strain Name:
C57BL/6J-MtgxR4943Btlr/Mmmh
Stock Number:
042540-MU
Citation ID:
RRID:MMRRC_042540-MU
Other Names:
R4943 (G1), C57BL/6J-MtgxR4943Btlr
Major Collection:

Gene Information

Atg7
Name: autophagy related 7
Synonyms: Apg7l, 1810013K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74244
Homologene: 4662
Mycn
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Synonyms: N-myc, Nmyc, Nmyc-1, Nmyc1, bHLHe37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18109
HGNC: HGNC:7559
Homologene: 3922
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: D630035I23Rik, 5430433L24Rik, TRIP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108829
Homologene: 3129
Mybl1
Name: myeloblastosis oncogene-like 1
Synonyms: G1-419-6, repro9, A-myb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17864
HGNC: HGNC:7547
Homologene: 32045
Cops4
Name: COP9 signalosome subunit 4
Synonyms: COP9 complex S4, D5Ertd774e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26891
Homologene: 8067
Zdbf2
Name: zinc finger, DBF-type containing 2
Synonyms: 4930431J08Rik, 9330107J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73884
Homologene: 52868
Tex21
Name: testis expressed gene 21
Synonyms: tsec-2, 4931406F04Rik, 4931412D23Rik, 4931421K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 80384
VEGA: 12
Homologene: 10510
Rapgef2
Name: Rap guanine nucleotide exchange factor (GEF) 2
Synonyms: 5830453M24Rik, nRapGEP, CNRasGEF, RA-GEF-1, Pdzgef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76089
Homologene: 35477
Dtx4
Name: deltex 4, E3 ubiquitin ligase
Synonyms: RNF155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 207521
VEGA: 19
Homologene: 27781
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: 9430080K19Rik, Nik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Auts2
Name: autism susceptibility candidate 2
Synonyms: 2700063G02Rik, D830032G16Rik, A730011F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319974
Homologene: 22907
Zfhx3
Name: zinc finger homeobox 3
Synonyms: A230102L03Rik, Sci, WBP9, Atbf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Etl4
Name: enhancer trap locus 4
Synonyms: 6620402G01Rik, E330027G05Rik, Etl-4, 9430077C05Rik, Sickle tail, Skt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 208618
Homologene: 10477
Nup205
Name: nucleoporin 205
Synonyms: 3830404O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70699
Homologene: 45971
Akap13
Name: A kinase (PRKA) anchor protein 13
Synonyms: PROTO-LBC, AKAP-Lbc, PROTO-LB, 5830460E08Rik, 5730522G15Rik, 1700026G02Rik, Ht31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Xpo4
Name: exportin 4
Synonyms: B430309A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57258
Homologene: 10733
Srrm2
Name: serine/arginine repetitive matrix 2
Synonyms: SRm300, 5033413A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75956
Aen
Name: apoptosis enhancing nuclease
Synonyms: 2700083B06Rik, Isg20l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68048
Homologene: 23382
Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: MLTKalpha, MLTKbeta, Zak, B230120H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65964
Homologene: 32331
Nat10
Name: N-acetyltransferase 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98956
Homologene: 6785
Dhx8
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 8
Synonyms: RNA helicase, Ddx8, mDEAH6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217207
HGNC: HGNC:2749
Homologene: 3628
Thbs1
Name: thrombospondin 1
Synonyms: TSP-1, Thbs-1, TSP1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Tdp2
Name: tyrosyl-DNA phosphodiesterase 2
Synonyms: D13Ertd656e, Ttrap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56196
Homologene: 9591
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: A730020P05Rik, Semaq, Sema6A-1, sema, VIa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20358
Homologene: 32426
Nktr
Name: natural killer tumor recognition sequence
Synonyms: 5330401F18Rik, D9Wsu172e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Zfp65
Name: zinc finger protein 65
Synonyms: Zfp71-rs1, KRAB5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 235907
Homologene: 87875
D16Ertd472e
Name: DNA segment, Chr 16, ERATO Doi 472, expressed
Synonyms: 1700010I10Rik, 2310009O17Rik, E330003K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67102
Homologene: 9696
Med23
Name: mediator complex subunit 23
Synonyms: Sur2, ESTM7, X83317, 3000002A17Rik, Crsp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Dcun1d5
Name: DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
Synonyms: 3110001A18Rik, 4833420K19Rik, D430047L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76863
VEGA: 9
Homologene: 9028
Tmem207
Name: transmembrane protein 207
Synonyms: LOC224058, 100043057
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 100043057
VEGA: 16
Homologene: 52611
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: LTRPC2, Trrp7, TRPC7, 9830168K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28240
Homologene: 20709
Ern2
Name: endoplasmic reticulum (ER) to nucleus signalling 2
Synonyms: Ire1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26918
Homologene: 22687
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Ftsj3
Name: FtsJ RNA methyltransferase homolog 3 (E. coli)
Synonyms: Epcs3, D11Ertd400e, C79843
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56095
Homologene: 5451
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, LOC245827, EMI2, mKIAA0811
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: Ccp4, Nna1-l1, EG244071
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244071
Homologene: 17552
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 192188
Homologene: 23022
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Wdr64
Name: WD repeat domain 64
Synonyms: 4930415O10Rik, 4930511H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75820
Homologene: 51634
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: MyHC-IIa, Myhsf1, Myhs-f1, MHC2A, Myhs-f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546981
Homologene: 115466
Olfr898
Name: olfactory receptor 898
Synonyms: MOR170-3, GA_x6K02T2PVTD-32037624-32038565
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258871
VEGA: 9
Homologene: 133654
Zfp947
Name: zinc finger protein 947
Synonyms: Gm4769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210853
Homologene: 133253
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241263
Homologene: 19381
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, 9430063L05Rik, 4732458A06Rik, D130016K21Rik, Usmg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83679
Homologene: 66961
Nt5dc1
Name: 5'-nucleotidase domain containing 1
Synonyms: 6030401B09Rik, Nt5c2l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319638
Homologene: 16281
Cldn10
Name: claudin 10
Synonyms: D14Ertd728e, Cldn10a, Cldn10b, 6720456I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 58187
HGNC: HGNC:2033
Homologene: 5076
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231589
Homologene: 129606
Calr3
Name: calreticulin 3
Synonyms: Crt2, 1700031L01Rik, calsperin, 6330586I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73316
Homologene: 57091
Zfp976
Name: zinc finger protein 976
Synonyms: 9830147E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 208111
Homologene: 134004
Gm5581
Name: predicted gene 5581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
2210408I21Rik
Name: RIKEN cDNA 2210408I21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72371
Homologene: 89234
Tm9sf1
Name: transmembrane 9 superfamily member 1
Synonyms: MP70, 1200014D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 74140
Homologene: 4671
Olfr1509
Name: olfactory receptor 1509
Synonyms: GA_x6K02T2RJGY-534312-533386, MOR83, MOR244-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57271
HGNC: HGNC:8297
Homologene: 41378
Aldh18a1
Name: aldehyde dehydrogenase 18 family, member A1
Synonyms: 2810433K04Rik, Pycs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56454
HGNC: HGNC:9722
Homologene: 2142
Myom3
Name: myomesin family, member 3
Synonyms: 8430427K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242702
Homologene: 19432
Klk14
Name: kallikrein related-peptidase 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 317653
HGNC: HGNC:6362
Homologene: 69348
Kif4-ps
Name: kinesin family member 4, pseudogene
Synonyms: Kif4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74947
Kif28
Name: kinesin family member 28
Synonyms: Gm1305, LOC383592
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 383592
Homologene: 130945
Nme3
Name: NME/NM23 nucleoside diphosphate kinase 3
Synonyms: non-metastatic cells 3, protein expressed in, 1810009F08Rik, Ndk3, DR-nm23, Nm23-M3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 79059
HGNC: HGNC:7851
Homologene: 20562
Gm10447
Name: predicted gene 10447
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Hectd2
Name: HECT domain E3 ubiquitin protein ligase 2
Synonyms: A630025O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226098
Homologene: 6280
Cpne4
Name: copine IV
Synonyms: 4933406O10Rik, 3632411M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74020
HGNC: HGNC:2317
Homologene: 26078
P4ha2
Name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
Synonyms: P4hl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18452
HGNC: HGNC:8547
Homologene: 55806
Actl9
Name: actin-like 9
Synonyms: 1700029I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69481
Homologene: 77642
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70719
Homologene: 69120
Aadacl4fm5
Name: AADACL4 family member 5
Synonyms: LOC329993, Gm438
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329993
Homologene: 135765
Stac2
Name: SH3 and cysteine rich domain 2
Synonyms: 24b2, 24b2/STAC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217154
Homologene: 17131
Rbms3
Name: RNA binding motif, single stranded interacting protein
Synonyms: 8430436O14Rik, 6720477E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 207181
Homologene: 49388
Rwdd2b
Name: RWD domain containing 2B
Synonyms: ORF5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 53858
HGNC: HGNC:1302
Homologene: 9654
Olfr630
Name: olfactory receptor 630
Synonyms: GA_x6K02T2PBJ9-6483085-6482126, MOR17-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259102
Homologene: 133674
2510039O18Rik
Name: RIKEN cDNA 2510039O18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77034
Homologene: 12668
Pxdc1
Name: PX domain containing 1
Synonyms: 1300014I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66895
Homologene: 12051
Zfp703
Name: zinc finger protein 703
Synonyms: 1110032O19Rik, End2, Csmn1, Zeppo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 353310
Homologene: 81391
Prokr1
Name: prokineticin receptor 1
Synonyms: Pkr1, EG-VEGFR1, Gpr73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58182
HGNC: HGNC:4524
Homologene: 10968
Gm26919
Name: predicted gene, 26919
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Homologene: 134227
Olfr106-ps
Name: olfactory receptor 106, pseudogene
Synonyms: GA_x6K02T2PSCP-1855511-1856437, Olfr106, MOR250-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 257925
Vmn1r227
Name: vomeronasal 1 receptor 227
Synonyms: V1re6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171229
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 9,681,851 bp
  • A to G, chromosome 1 at 40,019,594 bp
  • G to T, chromosome 1 at 63,302,914 bp
  • G to A, chromosome 1 at 175,720,316 bp
  • T to C, chromosome 1 at 179,713,951 bp
  • G to A, chromosome 2 at 20,807,281 bp
  • G to A, chromosome 2 at 21,827,157 bp
  • T to C, chromosome 2 at 31,335,492 bp
  • G to A, chromosome 2 at 72,371,918 bp
  • A to G, chromosome 2 at 103,721,862 bp
  • A to T, chromosome 2 at 118,113,449 bp
  • A to G, chromosome 3 at 38,980,173 bp
  • A to T, chromosome 3 at 79,064,547 bp
  • A to T, chromosome 3 at 97,755,511 bp
  • T to C, chromosome 4 at 135,814,274 bp
  • T to A, chromosome 4 at 144,777,720 bp
  • T to A, chromosome 4 at 147,945,098 bp
  • T to C, chromosome 5 at 14,712,637 bp
  • A to T, chromosome 5 at 100,547,426 bp
  • C to A, chromosome 5 at 109,175,049 bp
  • T to A, chromosome 5 at 131,440,156 bp
  • G to A, chromosome 5 at 137,457,890 bp
  • A to G, chromosome 6 at 35,224,639 bp
  • A to C, chromosome 6 at 87,581,824 bp
  • A to C, chromosome 6 at 114,697,084 bp
  • A to T, chromosome 6 at 130,676,200 bp
  • A to G, chromosome 6 at 131,167,125 bp
  • A to T, chromosome 7 at 42,612,422 bp
  • G to A, chromosome 7 at 43,692,077 bp
  • T to A, chromosome 7 at 75,749,240 bp
  • G to A, chromosome 7 at 76,420,016 bp
  • T to A, chromosome 7 at 78,902,361 bp
  • A to T, chromosome 7 at 86,165,497 bp
  • A to T, chromosome 7 at 103,755,296 bp
  • C to T, chromosome 7 at 122,173,258 bp
  • C to A, chromosome 8 at 26,979,591 bp
  • A to T, chromosome 8 at 72,431,377 bp
  • T to C, chromosome 8 at 108,948,317 bp
  • T to C, chromosome 9 at 7,186,844 bp
  • C to T, chromosome 9 at 38,349,628 bp
  • A to T, chromosome 9 at 105,019,773 bp
  • G to C, chromosome 9 at 116,678,505 bp
  • T to A, chromosome 9 at 121,719,954 bp
  • T to A, chromosome 10 at 24,875,669 bp
  • T to C, chromosome 10 at 34,310,391 bp
  • T to A, chromosome 10 at 67,096,263 bp
  • C to A, chromosome 10 at 77,966,007 bp
  • A to G, chromosome 10 at 80,026,503 bp
  • T to C, chromosome 10 at 86,954,162 bp
  • A to T, chromosome 11 at 53,456,389 bp
  • A to G, chromosome 11 at 54,129,525 bp
  • T to C, chromosome 11 at 55,279,033 bp
  • G to T, chromosome 11 at 67,197,317 bp
  • G to T, chromosome 11 at 98,041,572 bp
  • T to A, chromosome 11 at 101,737,700 bp
  • A to G, chromosome 11 at 106,249,518 bp
  • A to T, chromosome 12 at 12,937,079 bp
  • A to G, chromosome 12 at 76,221,700 bp
  • C to T, chromosome 12 at 101,149,217 bp
  • T to A, chromosome 13 at 24,838,265 bp
  • C to A, chromosome 13 at 34,639,006 bp
  • T to A, chromosome 13 at 67,710,980 bp
  • C to A, chromosome 13 at 77,245,327 bp
  • C to G, chromosome 14 at 52,450,594 bp
  • T to C, chromosome 14 at 55,641,168 bp
  • T to C, chromosome 14 at 57,638,240 bp
  • G to A, chromosome 14 at 118,788,313 bp
  • C to T, chromosome 16 at 26,517,853 bp
  • A to T, chromosome 16 at 78,575,989 bp
  • T to C, chromosome 16 at 87,434,534 bp
  • A to T, chromosome 17 at 20,735,361 bp
  • A to C, chromosome 17 at 22,145,832 bp
  • T to C, chromosome 17 at 23,822,415 bp
  • A to G, chromosome 17 at 24,896,723 bp
  • G to A, chromosome 17 at 33,433,085 bp
  • G to T, chromosome 17 at 37,395,025 bp
  • A to C, chromosome 18 at 47,287,545 bp
  • A to G, chromosome 19 at 12,501,060 bp
  • T to G, chromosome 19 at 36,604,247 bp
  • G to A, chromosome 19 at 40,574,328 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4943 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042540-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.